Maternal childhood trauma and postpartum well-being in a Turkish sample: The path from attachment to alexithymia

Childhood traumas predispose adult individuals to develop insecure attachment styles in close relationships and alexithymia features causing limitations in emotional capacity. For new mothers, postpartum is a period in itself that may increase mood problems such as depression and anxiety and mothers may question their efficacy in their maternal role. Thus, the purpose of the current research was to examine the relationship between maternal childhood trauma, mood problems, and self-efficacy via serial mediation of insecure attachment styles and alexithymia. A sample of postpartum Turkish mothers with healthy singleton infants (N = 63, Mage = 29.19) participated in the research. Mothers filled out the Childhood Trauma Questionnaire-Short Form, the Perceived Maternal Parenting Self-Efficacy Tool, CES-Depression Scale, the State-Trait Anxiety Inventory, the Experiences in Close Relationships Inventory-II, and the Toronto Alexithymia Scale during a home visit when the infants were one month old. In statistical analyses, the PROCESS macro for serial multiple mediation was applied. The results indicated that the relationship between maternal childhood trauma and postpartum depression and anxiety was serially mediated by anxious attachment and, in turn, alexithymia. On the other hand, the serial mediator roles of insecure attachment styles and alexithymia on the relationship between maternal childhood trauma and postpartum self-efficacy were not significant; rather, the direct effect of maternal childhood trauma on postpartum self-efficacy was significant. Findings suggest anxious, rather than avoidant, attachment, and alexithymia as intervention targets to buffer the effects of maternal childhood trauma on postpartum mood problems and self-efficacy, which may consequently prevent the intergenerational transmission of risk

Bilişsel psikoterapi sürecinde ilişkisel değişkenlerin incelenmesi: bağlanma biçimleri, kişiserarası şemalar ve terapötik ittifak

TÜBİTAK SOBAG Proje01.01.200

Discriminant Validity And Reliability Of The Turkish Version Of Informant Questionnaire On Cognitive Decline In The Elderly (Iqcode-T)

The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) has been used as a measure of cognitive decline in different cultures. The purpose of the study was to establish the validity and reliability of the Turkish version of IQCODE (IQCODE-T) and the ability of the questionnaire to distinguish between older adults with DSM-IV-TR dementia (n = 100) and healthy control participants (n = 60). In addition, the power of the IQCODE-T to distinguish between patients with depression and dementia was investigated. The Mini-Mental State Examination (MMSE) was performed on all participants and the IQCODE-T was administered to their informants. The IQCODE-T, which was not associated with age or education of the patients, significantly differentiated patients with dementia and controls. The IQCODE-T also correctly classified 73% of depressed patients as "non-demented". Because it is easy to administer, not associated with age/education and yields fewer false-positive results than the MMSE in depression, the IQCODE-T can be used in the detection of dementia.WoSScopu

Scientific and Ethical Evaluation of Obesity Weight Loss Competition Programs Broadcasted in the Media

Obezite yaşam kalitesini düşüren multifaktöriyel kronik bir hastalık olup tüm dünyada hızla yayılmaktadır. Günümüzde gelişmekte olan ülkeler başta olmak üzere, pek çok ülkede obezite ile mücadele konusunda politikalar geliştirilmekte, ulusal eylem planları hazırlanmaktadır. Ülkemizde de Sağlık Bakanlığı tarafından Türkiye Sağlıklı Beslenme ve Hareketli Hayat Programı başlatılmıştır. Ulusal programın Obezitenin Önlenmesine Yönelik Çalışmalar başlığı altında medya haberleri ve reklamlarda, yeterli ve dengeli beslenme ve düzenli fiziksel aktivitenin desteklenmesi hususu ele alınmış ve medyada yer alan gıda reklamlarına ve tanıtıcı faaliyetlere yönelik yasal düzenlemeleri güncellemek ve toplumu bilgilendirici bilimsel içerikli programların yayınlanmasını teşvik etmek iki ana hedef olarak belirlenmiştir. Bu kapsamda medyada, televizyon kanallarında yayınlanan morbid obezlere yönelik zayıflama yarışma programlarının bilimsel ve etik açıdan değerlendirilmesi ve gereksinme duyulan mevzuatın hazırlanmasına yönelik önerilerin bildirilmesi amaçlanmıştır. Yazılı ve görsel medyada ve internette web sitelerinde zaman zaman yayınlanan zayıflama yarışma programları bilimsel gerçeklere uygun olmadığı gibi etik ilkelerle de bağdaşmamaktadır.Obesity is a multi-factorial chronic disease, which decreases the quality of life and it spreads very fast all over the world. Today, particularly in the developed countries, obesity prevention policies have been developed and national action plans are prepared. In our country Healthy Nutrition and Active Life Program was also implemented by Ministry of Health. Under the title of Interventions for obesity prevention of the national program, supporting adequate and balanced nutrition and active life in media news and advertisements are considered. Two main targets are stated for this item. To update legal arrangements on food advertisements and introductory activities took place in the media and to encourage broadcasting of the informative scientific programs on adequate and balanced diet and physical activity. Within this scope, evaluating weight-loss competition programs that appear on TV channels from scientific and ethic aspects and to present advices for preparing legal regulation that required on this issue are targeted. Weight-loss competition programs that were sometimes broadcasted in media and internet web sites are not only based on scientific facts but also ethical issues

The correlates of benefit from neoadjuvant chemotherapy before surgery in non-small-cell lung cancer: a metaregression analysis

Background: Although neoadjuvant chemotherapy (NCT) is widely used, it is not clear which subgroup of locally advanced non-small-cell lung cancer (NSCLC) patients should be treated with this approach, and if a particular benefit associated with NCT exists. In this study, we aimed to investigate the potential correlates of benefit from NCT in patients with NSCLC.Methods: All randomized clinical trials (RCTs) utilizing a NCT arm (without radiotherapy) versus a control arm before surgery were included for metaregression analysis. All regression analyses were weighed for trial size. Separate analyses were conducted for trials recruiting patients with different stages of disease. Previously published measures of treatment efficacy were used for the purpose of this study, regardless of being published in full text or abstract form.Results: A total of 14 RCTs, consisting of 3,615 patients, were selected. Histology, stage, various characteristics of the NCT protocol, and different trial features including trial quality score were not associated with the benefit of NCT. However, in trials of stage 3 disease only, there was a greater benefit in terms of reduction in mortality from NCT, if protocols with three chemotherapeutics were used (B = -0.18, t = -5.25, P = 0.006).Conclusions: We think that patients with stage 3 NSCLC are served better with NCT before surgery if protocols with three chemotherapy agents or equally effective combinations are used. In addition, the effect of neoadjuvant chemotherapy is consistent with regard to disease and patient characteristics. This finding should be tested in future RCTs or individual patient data meta-analyses. © 2012 Bozcuk et al.; licensee BioMed Central Ltd

Re-examining the characteristics of pediatric multiple sclerosis in the era of antibody-associated demyelinating syndromes.

Background: The discovery of anti-myelin oligodendrocyte glycoprotein (MOG)-IgG and anti-aquaporin 4 (AQP4)-IgG and the observation on certain patients previously diagnosed with multiple sclerosis (MS) actually have an antibody-mediated disease mandated re-evaluation of pediatric MS series. Aim: To describe the characteristics of recent pediatric MS cases by age groups and compare with the cohort established before 2015. Method: Data of pediatric MS patients diagnosed between 2015 and 2021 were collected from 44 pediatric neurology centers across Turkiye. Clinical and paraclinical features were compared between patients with dis-ease onset before 12 years (earlier onset) and >= 12 years (later onset) as well as between our current (2015-2021) and previous (< 2015) cohorts. Results: A total of 634 children (456 girls) were enrolled, 89 (14%) were of earlier onset. The earlier-onset group had lower female/male ratio, more frequent initial diagnosis of acute disseminated encephalomyelitis (ADEM), more frequent brainstem symptoms, longer interval between the first two attacks, less frequent spinal cord involvement on magnetic resonance imaging (MRI), and lower prevalence of cerebrospinal fluid (CSF)-restricted oligoclonal bands (OCBs). The earlier-onset group was less likely to respond to initial disease-modifying treatments. Compared to our previous cohort, the current series had fewer patients with onset < 12 years, initial presentation with ADEM-like features, brainstem or cerebellar symptoms, seizures, and spinal lesions on MRI. The female/male ratio, the frequency of sensorial symptoms, and CSF-restricted OCBs were higher than reported in our previous cohort. Conclusion: Pediatric MS starting before 12 years was less common than reported previously, likely due to exclusion of patients with antibody-mediated diseases. The results underline the importance of antibody testing and indicate pediatric MS may be a more homogeneous disorder and more similar to adult-onset MS than previously thought