A novel method for unambiguous ion identification in mixed ion beams extracted from an EBIT

A novel technique to identify small fluxes of mixed highly charged ion beams extracted from an Electron Beam Ion Trap (EBIT) is presented and practically demonstrated. The method exploits projectile charge state dependent potential emission of electrons as induced by ion impact on a metal surface to separate ions with identical or very similar mass-to-charge ratio.Comment: 8 pages, 5 figure

Degenerate ground states and nonunique potentials: breakdown and restoration of density functionals

The Hohenberg-Kohn (HK) theorem is one of the most fundamental theorems of quantum mechanics, and constitutes the basis for the very successful density-functional approach to inhomogeneous interacting many-particle systems. Here we show that in formulations of density-functional theory (DFT) that employ more than one density variable, applied to systems with a degenerate ground state, there is a subtle loophole in the HK theorem, as all mappings between densities, wave functions and potentials can break down. Two weaker theorems which we prove here, the joint-degeneracy theorem and the internal-energy theorem, restore the internal, total and exchange-correlation energy functionals to the extent needed in applications of DFT to atomic, molecular and solid-state physics and quantum chemistry. The joint-degeneracy theorem constrains the nature of possible degeneracies in general many-body systems

NF-κB activation protects oligodendrocytes against inflammation

NF-κB is a key player in inflammatory diseases, including multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). However, the effects of NF-κB activation on oligodendrocytes in MS and EAE remain unknown. We generated a mouse model that expresses IκBαΔN, a super-suppressor of NF-κB, specifically in oligodendrocytes and demonstrated that IκBαΔN expression had no effect on oligodendrocytes under normal conditions (both sexes). Interestingly, we showed that oligodendrocyte-specific expression of IκBαΔN blocked NF-κB activation in oligodendrocytes and resulted in exacerbated oligodendrocyte death and hypomyelination in young, developing mice that ectopically express IFN-γ in the CNS (both sexes). We also showed that NF-κB inactivation in oligodendrocytes aggravated IFN-γ-induced remyelinating oligodendrocyte death and remyelination failure in the cuprizone model (male mice). Moreover, we found that NF-κB inactivation in oligodendrocytes increased the susceptibility of mice to EAE (female mice). These findings imply the cytoprotective effects of NF-κB activation on oligodendrocytes in MS and EAE

Theoretical Description of Two- and Three-Particle Interactions in Single Ionization of Helium by Ion Impact

In this work we calculate doubly differential cross sections (DDCS) for single ionization of helium by highly charged ion impact. We study the importance of two-particle interactions in these processes by considering the cross sections as a function of all two-particle subsystems momenta. Experimental DDCSs were obtained recently from kinematically complete experiments on single ionization of He by 100 MeV/amu C6+ and 3.6 MeV/amu Au24,53+ impact. Furthermore, we evaluated the importance of three-particle interactions by plotting the squared momenta of all three collision fragments simultaneously in a Dalitz plot. Using the first Born and distorted-wave approximations for fully differential cross sections, together with Monte Carlo integration techniques, we were able to reproduce the main features observed in experimental data and to assess the quality of the models implied by the different employed approximations

A Comprehensive New Detector for Detailed Study of the Quark Gluon Plasma, Initial Conditions and Spin Physics at RHIC II

A case is presented for compelling physics at a high luminosity RHIC II collider and a comprehensive new detector system to address this physics. The experimental focus is on detailed jet tomography of the quark gluon plasma (QGP), measuring gluon saturation in the nucleus, investigating the color glass condensate, measuring effects of the QCD vacuum on particle masses, determining the structure and dynamics within the proton, and possible new phenomena. The physics and detector capabilities are introduced.Comment: Proceedings 20th Winter Workshop on Nuclear Dynamics, Trelawny Beach, Jamaica, March 15--20, 2004. 12 pages, 4 figure

Density-potential mappings in quantum dynamics

In a recent letter [Europhys. Lett. 95, 13001 (2011)] the question of whether the density of a time-dependent quantum system determines its external potential was reformulated as a fixed point problem. This idea was used to generalize the existence and uniqueness theorems underlying time-dependent density functional theory. In this work we extend this proof to allow for more general norms and provide a numerical implementation of the fixed-point iteration scheme. We focus on the one-dimensional case as it allows for a more in-depth analysis using singular Sturm-Liouville theory and at the same time provides an easy visualization of the numerical applications in space and time. We give an explicit relation between the boundary conditions on the density and the convergence properties of the fixed-point procedure via the spectral properties of the associated Sturm-Liouville operator. We show precisely under which conditions discrete and continuous spectra arise and give explicit examples. These conditions are then used to show that in the most physically relevant cases the fixed point procedure converges. This is further demonstrated with an example.Comment: 20 pages, 8 figures, 3 table

The Emerging QCD Frontier: The Electron Ion Collider

The self-interactions of gluons determine all the unique features of QCD and lead to a dominant abundance of gluons inside matter already at moderate $x$. Despite their dominant role, the properties of gluons remain largely unexplored. Tantalizing hints of saturated gluon densities have been found in $e$+p collisions at HERA, and in d+Au and Au+Au collisions at RHIC. Saturation physics will have a profound influence on heavy-ion collisions at the LHC. But unveiling the collective behavior of dense assemblies of gluons under conditions where their self-interactions dominate will require an Electron-Ion Collider (EIC): a new facility with capabilities well beyond those In this paper I outline the compelling physics case for $e$+A collisions at an EIC and discuss briefly the status of machine design concepts. of any existing accelerator.Comment: 11 pages, 9 figures, prepared for 20th International Conference on Ultra-Relativistic Nucleus-Nucleus Collisions: Quark Matter 2008 (QM2008), Jaipur, India, 4-10 Feb. 200

Evolution of dopant-induced helium nanoplasmas

Two-component nanoplasmas generated by strong-field ionization of doped helium nanodroplets are studied in a pump-probe experiment using few-cycle laser pulses in combination with molecular dynamics simulations. High yields of helium ions and a pronounced, droplet size-dependent resonance structure in the pump-probe transients reveal the evolution of the dopant-induced helium nanoplasma. The pump-probe dynamics is interpreted in terms of strong inner ionization by the pump pulse and resonant heating by the probe pulse which controls the final charge states detected via the frustration of electron-ion recombination