5 research outputs found
Tunable local polariton modes in semiconductors
We study the local states within the polariton bandgap that arise due to deep
defect centers with strong electron-phonon coupling. Electron transitions
involving deep levels may result in alteration of local elastic constants. In
this case, substantial reversible transformations of the impurity polariton
density of states occur, which include the appearance/disappearance of the
polariton impurity band, its shift and/or the modification of its shape. These
changes can be induced by thermo- and photo-excitation of the localized
electron states or by trapping of injected charge carriers. We develop a simple
model, which is applied to the center in . Further possible
experimental realizations of the effect are discussed.Comment: 7 pages, 3 figure
Characterization of Self-Assembled Polyelectrolyte Complex Nanoparticles Formed from Chitosan and Pectin
Chronic wounds continue to be a global healthcare concern. Thus, the development of new nanoparticle-based therapies that treat multiple symptoms of these “non-healing” wounds without encouraging antibiotic resistance is imperative. One potential solution is to use chitosan, a naturally antimicrobial polycation, which can spontaneously form polyelectrolyte complexes when mixed with a polyanion in appropriate aqueous conditions. The requirement of at least two different polymers opens up the opportunity for us to form chitosan complexes with an additional functional polyanion. In this study, chitosan:pectin (CS:Pec) nanoparticles were synthesized using an aqueous spontaneous ionic gelation method. Systematically, a number of parameters, polymer concentration, addition order, mass ratio, and solution pH, were explored and their effect on nanoparticle formation was determined. The size and surface charge of the particles were characterized, as well as their morphology using transmission electron microscopy. The effect of polymer concentration and addition order on the nanoparticles was found to be similar to that of other chitosan:polyanion complexes. The mass ratio was tuned to create nanoparticles with a chitosan shell and a controllable positive zeta potential. The particles were stable in a pH range from 3.5 to 6.0 and lost stability after 14 days of storage in aqueous media. Due to the high positive surface charge of the particles, the innate properties of the polysaccharides used, and the harmless disassociation of the polyelectrolytes, we suggest that the development of these CS:Pec nanoparticles offers great promise as a chronic wound healing platform