3,006 research outputs found
Three-Nucleon Force and the -Mechanism for Pion Production and Pion Absorption
The description of the three-nucleon system in terms of nucleon and
degrees of freedom is extended to allow for explicit pion production
(absorption) from single dynamic de-excitation (excitation) processes.
This mechanism yields an energy dependent effective three-body hamiltonean. The
Faddeev equations for the trinucleon bound state are solved with a force model
that has already been tested in the two-nucleon system above pion-production
threshold. The binding energy and other bound state properties are calculated.
The contribution to the effective three-nucleon force arising from the pionic
degrees of freedom is evaluated. The validity of previous coupled-channel
calculations with explicit but stable isobar components in the
wavefunction is studied.Comment: 23 pages in Revtex 3.0, 9 figures (not included, available as
postscript files upon request), CEBAF-TH-93-0
Methylation landscape in the genome of higher plants of agronomical interest
In eukaryotic cells the methylation of cytosines in DNA is an essential mechanism which is implied in the dynamic organization of the genome structure, in relation to genes expression. Plant genomes contain a significant proportion and variable according to the species, of sequences which are likely to be methylated during the life of the plant. It is known that the establishment and the maintenance of methylation profiles in both genomic areas and specific sequences constitute a crucial mediator in the modulation of genes expression during development. Recent studies have evidenced the implication of epimutations in the adaptation of plants to their environment particularly in response to biotic and abiotic stresses. Recently, the complete mapping of methylation in the genomes of Arabidopsis thaliana and rice provided invaluable information on the distribution of methylation within genes in relation to their expression. The impact of changes in the methylation profiles on the characters of agronomic importance has not been intensively studied yet, whereas this question takes a considerable importance in the context of an increasing food demand and foreseen global climate changes. The METHYLANDSCAPE project proposes to isolate genomic DNA sequences on the basis of their degree of methylation and to connect the variation of their methylation profiles with, on the one hand, the expression of the corresponding genes and, on the other hand, with environmental or developmental processes. Thus, it should be possible to identify genes which expression is differentially controlled by methylation during development and/or in situation of stress, and likely to have an influence on the agronomic value of the plant. The METHYLANDSCAPE partners thus propose to bring signification advances in plant genomics on four original species, by integrating DNA methylation mapping and the relationship between epigenome and transcriptome, up to the generation of methylation-sensitive markers linked with characters of agronomic importance. (Texte intégral
Towards a Mg lattice clock: Observation of the transition and determination of the magic wavelength
We optically excite the electronic state in Mg atoms,
laser-cooled and trapped in a magic-wavelength lattice. An applied magnetic
field enhances the coupling of the light to the otherwise strictly forbidden
transition. We determine the magic wavelength, the quadratic magnetic Zeeman
shift and the transition frequency to be 468.463(207)nm,
-206.6(2.0)MHz/T and 655 058 646 691(101)kHz, respectively. These
are compared with theoretical predictions and results from complementary
experiments. We also developed a high-precision relativistic structure model
for magnesium, give an improved theoretical value for the blackbody radiation
shift and discuss a clock based on bosonic magnesium.Comment: 5 pages, 3 figure
Benchmark calculation for proton-deuteron elastic scattering observables including Coulomb
Two independent calculations of proton-deuteron elastic scattering
observables including Coulomb repulsion between the two protons are compared in
the proton lab energy region between 3 MeV and 65 MeV. The hadron dynamics is
based on the purely nucleonic charge-dependent AV18 potential. Calculations are
done both in coordinate space and momentum space. The coordinate-space
calculations are based on a variational solution of the three-body
Schr\"odinger equation using a correlated hyperspherical expansion for the wave
function. The momentum-space calculations proceed via the solution of the
Alt-Grassberger-Sandhas equation using the screened Coulomb potential and the
renormalization approach. Both methods agree within 1% on all observables,
showing the reliability of both numerical techniques in that energy domain. At
energies below three-body breakup threshold the coordinate-space method remains
favored whereas at energies higher than 65 MeV the momentum-space approach
seems to be more efficient.Comment: Submitted to Phys. Rev.
Practical approximation scheme for the pion dynamics in the three-nucleon system
We discuss a working approximation scheme to a recently developed formulation
of the coupled piNNN-NNN problem. The approximation scheme is based on the
physical assumption that, at low energies, the 2N-subsystem dynamics in the
elastic channel is conveniently described by the usual 2N-potential approach,
while the explicit pion dynamics describes small, correction-type effects.
Using the standard separable-expansion method, we obtain a dynamical equation
of the Alt-Grassberger-Sandhas (AGS) type. This is an important result, because
the computational techniques used for solving the normal AGS equation can also
be used to describe the pion dynamics in the 3N system once the matrix
dimension is increased by one component. We have also shown that this
approximation scheme treats the conventional 3N problem once the pion degrees
of freedom are projected out. Then the 3N system is described with an extended
AGS-type equation where the spin-off of the pion dynamics (beyond the 2N
potential) is taken into account in additional contributions to the driving
term. These new terms are shown to reproduce the diagrams leading to modern
3N-force models. We also recover two sets of irreducible diagrams that are
commonly neglected in 3N-force discussions, and conclude that these sets should
be further investigated, because a claimed cancellation is questionable.Comment: 18 pages, including 5 figures, RevTeX, Eps
Unzipping Kinetics of Double-Stranded DNA in a Nanopore
We studied the unzipping kinetics of single molecules of double-stranded DNA
by pulling one of their two strands through a narrow protein pore. PCR analysis
yielded the first direct proof of DNA unzipping in such a system. The time to
unzip each molecule was inferred from the ionic current signature of DNA
traversal. The distribution of times to unzip under various experimental
conditions fit a simple kinetic model. Using this model, we estimated the
enthalpy barriers to unzipping and the effective charge of a nucleotide in the
pore, which was considerably smaller than previously assumed.Comment: 10 pages, 5 figures, Accepted: Physics Review Letter
Generalized isothermic lattices
We study multidimensional quadrilateral lattices satisfying simultaneously
two integrable constraints: a quadratic constraint and the projective Moutard
constraint. When the lattice is two dimensional and the quadric under
consideration is the Moebius sphere one obtains, after the stereographic
projection, the discrete isothermic surfaces defined by Bobenko and Pinkall by
an algebraic constraint imposed on the (complex) cross-ratio of the circular
lattice. We derive the analogous condition for our generalized isthermic
lattices using Steiner's projective structure of conics and we present basic
geometric constructions which encode integrability of the lattice. In
particular, we introduce the Darboux transformation of the generalized
isothermic lattice and we derive the corresponding Bianchi permutability
principle. Finally, we study two dimensional generalized isothermic lattices,
in particular geometry of their initial boundary value problem.Comment: 19 pages, 11 figures; v2. some typos corrected; v3. new references
added, higlighted similarities and differences with recent papers on the
subjec
Fundamental scaling laws of on-off intermittency in a stochastically driven dissipative pattern forming system
Noise driven electroconvection in sandwich cells of nematic liquid crystals
exhibits on-off intermittent behaviour at the onset of the instability. We
study laser scattering of convection rolls to characterize the wavelengths and
the trajectories of the stochastic amplitudes of the intermittent structures.
The pattern wavelengths and the statistics of these trajectories are in
quantitative agreement with simulations of the linearized electrohydrodynamic
equations. The fundamental distribution law for the durations
of laminar phases as well as the power law of the amplitude distribution
of intermittent bursts are confirmed in the experiments. Power spectral
densities of the experimental and numerically simulated trajectories are
discussed.Comment: 20 pages and 17 figure
Why is the three-nucleon force so odd?
By considering a class of diagrams which has been overlooked also in the most
recent literature on three-body forces, we extract a new contribution to the
three-nucleon interaction which specifically acts on the triplet odd states of
the two nucleon subsystem. In the static approximation, this 3N-force
contribution is fixed by the underlying 2N interaction, so in principle there
are no free parameters to adjust. The 2N amplitude however enters in the 3NF
diagram in a form which cannot be directly accessed or constrained by NN
phase-shift analysis. We conclude that this new 3N-force contribution provides
a mechanism which implies that the presence of the third nucleon modifies the
p-wave (and possibly the f-wave) components of the 2N subsystem in the
triplet-isotriplet channels.Comment: 10 Pages, 7 figures, RevTeX, twocolumn, epsf (updated version with
minor changes
A Y2H-seq approach defines the human protein methyltransferase interactome
To accelerate high-density interactome mapping, we developed a yeast two-hybrid interaction screening approach involving short-read second-generation sequencing (Y2H-seq) with improved sensitivity and a quantitative scoring readout allowing rapid interaction validation. We applied Y2H-seq to investigate enzymes involved in protein methylation, a largely unexplored post-translational modification. The reported network of 523 interactions involving 22 methyltransferases or demethylases is comprehensively annotated and validated through coimmunoprecipitation experiments and defines previously undiscovered cellular roles of nonhistone protein methylation
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