250 research outputs found
Effects of Boundary Conditions on Single-File Pedestrian Flow
In this paper we investigate effects of boundary conditions on one
dimensional pedestrian flow which involves purely longitudinal interactions.
Qualitatively, stop-and-go waves are observed under closed boundary condition
and dissolve when the boundary is open. To get more detailed information the
fundamental diagrams of the open and closed systems are compared using
Voronoi-based measurement method. Higher maximal specific flow is observed from
the pedestrian movement at open boundary condition
Properties of pedestrians walking in line: Stepping behavior
In human crowds, interactions among individuals give rise to a variety of
self-organized collective motions that help the group to effectively solve the
problem of coordination. However, it is still not known exactly how humans
adjust their behavior locally, nor what are the direct consequences on the
emergent organization. One of the underlying mechanisms of adjusting individual
motions is the stepping dynamics. In this paper, we present first quantitative
analysis on the stepping behavior in a one-dimensional pedestrian flow studied
under controlled laboratory conditions. We find that the step length is
proportional to the velocity of the pedestrian, and is directly related to the
space available in front of him, while the variations of the step duration are
much smaller. This is in contrast with locomotion studies performed on isolated
pedestrians and shows that the local density has a direct influence on the
stepping characteristics. Furthermore, we study the phenomena of
synchronization -walking in lockstep- and show its dependence on flow
densities. We show that the synchronization of steps is particularly important
at high densities, which has direct impact on the studies of optimizing
pedestrians flow in congested situations. However, small synchronization and
antisynchronization effects are found also at very low densities, for which no
steric constraints exist between successive pedestrians, showing the natural
tendency to synchronize according to perceived visual signals.Comment: 8 pages, 5 figure
Hyper-systolic processing on APE100\/Quadrics: n-loop computations
We investigate the performance gains from hyper-systolic implementations of n^2-loop problems on the massively parallel computer Quadrics, exploiting its 3-dimensional interprocessor connectivity. For illustration we study the communication aspects of an exact molecular dynamics simulation of n particles with Coulomb (or gravitational) interactions. We compare the interprocessor communication costs of the standard-systolic and the hyper-systolic approaches for various granularities. We predict gain factors as large as 3 on the Q4 and 8 on the QH4 and measure actual performances on these machine configurations. We conclude that it appears feasile to investigate the thermodynamics of a full gravitating n-body problem with O(10000) particles using the new method on a QH4 system
Pedestrian Traffic: on the Quickest Path
When a large group of pedestrians moves around a corner, most pedestrians do
not follow the shortest path, which is to stay as close as possible to the
inner wall, but try to minimize the travel time. For this they accept to move
on a longer path with some distance to the corner, to avoid large densities and
by this succeed in maintaining a comparatively high speed. In many models of
pedestrian dynamics the basic rule of motion is often either "move as far as
possible toward the destination" or - reformulated - "of all coordinates
accessible in this time step move to the one with the smallest distance to the
destination". Atop of this rule modifications are placed to make the motion
more realistic. These modifications usually focus on local behavior and neglect
long-ranged effects. Compared to real pedestrians this leads to agents in a
simulation valuing the shortest path a lot better than the quickest. So, in a
situation as the movement of a large crowd around a corner, one needs an
additional element in a model of pedestrian dynamics that makes the agents
deviate from the rule of the shortest path. In this work it is shown, how this
can be achieved by using a flood fill dynamic potential field method, where
during the filling process the value of a field cell is not increased by 1, but
by a larger value, if it is occupied by an agent. This idea may be an obvious
one, however, the tricky part - and therefore in a strict sense the
contribution of this work - is a) to minimize unrealistic artifacts, as naive
flood fill metrics deviate considerably from the Euclidean metric and in this
respect yield large errors, b) do this with limited computational effort, and
c) keep agents' movement at very low densities unaltered
The Fundamental Diagram of Pedestrian Movement Revisited
The empirical relation between density and velocity of pedestrian movement is
not completely analyzed, particularly with regard to the `microscopic' causes
which determine the relation at medium and high densities. The simplest system
for the investigation of this dependency is the normal movement of pedestrians
along a line (single-file movement). This article presents experimental results
for this system under laboratory conditions and discusses the following
observations: The data show a linear relation between the velocity and the
inverse of the density, which can be regarded as the required length of one
pedestrian to move. Furthermore we compare the results for the single-file
movement with literature data for the movement in a plane. This comparison
shows an unexpected conformance between the fundamental diagrams, indicating
that lateral interference has negligible influence on the velocity-density
relation at the density domain . In addition we test a
procedure for automatic recording of pedestrian flow characteristics. We
present preliminary results on measurement range and accuracy of this method.Comment: 13 pages, 9 figure
Ganglioside composition and histology of a spontaneous metastatic brain tumour in the VM mouse
Glycosphingolipid abnormalities have long been implicated in tumour malignancy and metastasis. Gangliosides are a family of sialic acid-containing glycosphingolipids that modulate cell–cell and cell–matrix interactions. Histology and ganglioside composition were examined in a natural brain tumour of the VM mouse strain. The tumour is distinguished from other metastatic tumour models because it arose spontaneously and metastasizes to several organs including brain and spinal cord after subcutaneous inoculation of tumour tissue in the flank. By electron microscopy, the tumour consisted of cells (15 to 20 μm in diameter) that had slightly indented nuclei and scant cytoplasm. The presence of smooth membranes with an absence of junctional complexes was a characteristic ultrastructural feature. No positive immunostaining was found for glial or neuronal markers. The total ganglioside sialic acid content of the subcutaneously grown tumour was low (12.6 ± 0.9 μg per 100 mg dry wt, n= 6 separate tumours) and about 70% of this was in the form of N-glycolylneuraminic acid. In contrast, the ganglioside content of the cultured VM tumour cells was high (248.4 ± 4.4 μg, n= 3) and consisted almost exclusively of N-acetylneuraminic acid. The ganglioside pattern of the tumour grown subcutaneously was complex, while GM3, GM2, GM1, and GD1a were the major gangliosides in the cultured tumour cells. This tumour will be a useful natural model for evaluating the role of gangliosides and other glycolipids in tumour cell invasion and metastasis. © 2001 Cancer Research Campaign http://www.bjcancer.co
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