Bursty bulk flow turbulence as a source of energetic particles to the outer radiation belt

We report observations of a Bursty Bulk Flow (BBF) penetrating close to the outer edge of the radiation belt. The turbulent BBF braking region is characterized by ion velocity fluctuations, magnetic field (B) variations, and intense electric fields (E). In this event, energetic (>100 keV) electron and ion fluxes are appreciably enhanced. Importantly, fluctuations in energetic electrons and ions suggest local energization. Using correlation distances and other observed characteristics of turbulent E, test-particle simulations support local energization by E that favors higher-energy electrons and leads to an enhanced energetic shoulder and tail in the electron distributions. The energetic shoulder and tail could be amplified to MeV energies by adiabatic transport into the radiation belt where |B| is higher. This analysis suggests that turbulence generated by BBFs can, in part, supply energetic particles to the outer radiation belt and that turbulence can be a significant contributor to particle acceleration

An economic evaluation of Wolbachia deployments for dengue control in Vietnam

INTRODUCTION: Dengue is a major public health challenge and a growing problem due to climate change. The release of Aedes aegypti mosquitoes infected with the intracellular bacterium Wolbachia is a novel form of vector control against dengue. However, there remains a need to evaluate the benefits of such an intervention at a large scale. In this paper, we evaluate the potential economic impact and cost-effectiveness of scaled Wolbachia deployments as a form of dengue control in Vietnam-targeted at the highest burden urban areas. METHODS: Ten settings within Vietnam were identified as priority locations for potential future Wolbachia deployments (using a population replacement strategy). The effectiveness of Wolbachia deployments in reducing the incidence of symptomatic dengue cases was assumed to be 75%. We assumed that the intervention would maintain this effectiveness for at least 20 years (but tested this assumption in the sensitivity analysis). A cost-utility analysis and cost-benefit analysis were conducted. RESULTS: From the health sector perspective, the Wolbachia intervention was projected to cost US$420 per disability-adjusted life year (DALY) averted. From the societal perspective, the overall cost-effectiveness ratio was negative, i.e. the economic benefits outweighed the costs. These results are contingent on the long-term effectiveness of Wolbachia releases being sustained for 20 years. However, the intervention was still classed as cost-effective across the majority of the settings when assuming only 10 years of benefits. CONCLUSION: Overall, we found that targeting high burden cities with Wolbachia deployments would be a cost-effective intervention in Vietnam and generate notable broader benefits besides health gains

An extragalactic supernebula confined by gravity

Little is known about the origins of the giant star clusters known as globular clusters. How can hundreds of thousands of stars form simultaneously in a volume only a few light years across the distance of the sun to its nearest neighbor? Radiation pressure and winds from luminous young stars should disperse the star-forming gas and disrupt the formation of the cluster. Globular clusters in our Galaxy cannot provide answers; they are billions of years old. Here we report the measurement of infrared hydrogen recombination lines from a young, forming super star cluster in the dwarf galaxy, NGC 5253. The lines arise in gas heated by a cluster of an estimated million stars, so young that it is still enshrouded in gas and dust, hidden from optical view. We verify that the cluster contains 4000-6000 massive, hot "O" stars. Our discovery that the gases within the cluster are bound by gravity may explain why these windy and luminous O stars have not yet blown away the gases to allow the cluster to emerge from its birth cocoon. Young clusters in "starbursting" galaxies in the local and distant universe may be similarly gravitationally confined and cloaked from view.Comment: Letter to Natur

Global impacts of a Foreshock Bubble: Magnetosheath, magnetopause and ground-based observations

This research at Imperial College London was funded by STFC Grants ST/I505713/1, ST/K001051/1 and ST/G00725X/1. D.L. Turner is thankful for funding from NASA (THEMIS mission and Grant NNX14AC16G). We acknowledge NASA Contract NAS5-02099 and V. Angelopoulos for the use of data from the THEMIS Mission, specifically C.W. Carlson and J.P. McFadden for the use of ESA data; D. Larson and R.P. Lin for the use of SST data; J.W. Bonnell and F.S. Mozer for the use of EFI data; and K.H. Glassmeier, U. Auster and W. Baumjohann for the use of FGM data provided under the lead of the Technical University of Braunschweig and with financial support through the German Ministry for Economy and Technology and the German Center for Aviation and Space (DLR) under Contract 50 OC 0302

The effect of mixing entire male pigs prior to transport to slaughter on behaviour, welfare and carcass lesions

peer-reviewedData set for article is also provided.Research is needed to validate lesions recorded at meat inspection as indicators of pig welfare on farm. The aims were to determine the influence of mixing pigs on carcass lesions and to establish whether such lesions correlate with pig behaviour and lesions scored on farm. Aggressive and mounting behaviour of pigs in three single sex pens was recorded on Day −5, −2, and −1 relative to slaughter (Day 0). On Day 0 pigs were randomly allocated to 3 treatments (n = 20/group) over 5 replicates: males mixed with females (MF), males mixed with males (MM), and males unmixed (MUM). Aggressive and mounting behaviours were recorded on Day 0 at holding on farm and lairage. Skin/tail lesions were scored according to severity at the farm (Day −1), lairage, and on the carcass (Day 0). Effect of treatment and time on behaviour and lesions were analysed by mixed models. Spearman rank correlations between behaviour and lesion scores and between scores recorded at different stages were determined. In general, MM performed more aggressive behaviour (50.4 ± 10.72) than MUM (20.3 ± 9.55, P < 0.05) and more mounting (30.9 ± 9.99) than MF (11.4 ± 3.76) and MUM (9.8 ± 3.74, P < 0.05). Skin lesion scores increased between farm (Day −1) and lairage (P < 0.001), but this tended to be significant only for MF and MM (P = 0.08). There was no effect of treatment on carcass lesions and no associations were found with fighting/mounting. Mixing entire males prior to slaughter stimulated mounting and aggressive behaviour but did not influence carcass lesion scores. Carcass skin/tail lesions scores were correlated with scores recorded on farm (rskin = 0.21 and rtail = 0.18, P < 0.01) suggesting that information recorded at meat inspection could be used as indicators of pig welfare on farm.This study was part of the PIGWELFIND project funded by the Department of Agriculture, Food and the Marine (DAFM), Ireland

Return of the Great Spaghetti Monster : Learnings from a Twelve-Year Adventure in Web Software Development

The widespread adoption of the World Wide Web has fundamentally changed the landscape of software development. Only ten years ago, very few developers would write software for the Web, let alone consider using JavaScript or other web technologies for writing any serious software applications. In this paper, we reflect upon a twelve-year adventure in web development that began with the development of the Lively Kernel system at Sun Microsystems Labs in 2006. Back then, we also published some papers that identified important challenges in web-based software development based on established software engineering principles. We will revisit our earlier findings and compare the state of the art in web development today to our earlier learnings, followed by some reflections and suggestions for the road forward.Peer reviewe