Thermal behaviors of light unflavored tensor mesons in the framework of QCD sum rule

In this study, we investigate the sensitivity of the masses and decay constants of the light $f_{2}(1270)$ and $a_{2}(1320)$ tensor mesons to the temperature using QCD sum rule approach. In our calculations, we take into account the additional operators appearing in operator product expansion at finite temperature. It is obtained that at deconfinement temperature the decay constants and masses decrease with amount of $6\%$ and $96\%$ compared to their vacuum values, respectively. Our results on the masses at zero temperature are consistent with the vacuum sum rules predictions as well as the experimental data.Comment: 4 Pages and 1 Table, Prepared for the proceeding of the 4th International Conference on Hadron Physics (TROIA'14

Thermal QCD Sum Rules Study of Vector Charmonium and Bottomonium States

We calculate the masses and leptonic decay constants of the heavy vector quarkonia, $J/\psi$ and $\Upsilon$ mesons at finite temperature. In particular, considering the thermal spectral density as well as additional operators coming up at finite temperature, the thermal QCD sum rules are acquired. Our numerical calculations demonstrate that the masses and decay constants are insensitive to the variation of temperature up to $T\cong 100 ~MeV$, however after this point, they start to fall altering the temperature. At deconfinement temperature, the decay constants attain roughly to 45% of their vacuum values, while the masses are diminished about 12%, and 2.5% for $J/\psi$ and $\Upsilon$ states, respectively. The obtained results at zero temperature are in good consistency with the existing experimental data as well as predictions of the other nonperturbative models. Considerable decreasing in the values of the decay constants can be considered as a sign of the quark gluon plasma phase transition.Comment: 14 Pages, 8 Figures and 2 Table

Drug-resistant HIV-1 protease regains functional dynamics through cleavage site coevolution

Drug resistance is caused by mutations that change the balance of recognition favoring substrate cleavage over inhibitor binding. Here, a structural dynamics perspective of the regained wild-type functioning in mutant HIV-1 proteases with coevolution of the natural substrates is provided. The collective dynamics of mutant structures of the protease bound to p1-p6 and NC-p1 substrates are assessed using the Anisotropic Network Model (ANM). The drug-induced protease mutations perturb the mechanistically crucial hinge axes that involve key sites for substrate binding and dimerization and mainly coordinate the intrinsic dynamics. Yet with substrate coevolution, while the wild-type dynamic behavior is restored in both p1-p6 ((LP) (1\u27F)p1-p6D30N/N88D) and NC-p1 ((AP) (2) (V)NC-p1V82A) bound proteases, the dynamic behavior of the NC-p1 bound protease variants (NC-p1V82A and (AP) (2) (V)NC-p1V82A) rather resemble those of the proteases bound to the other substrates, which is consistent with experimental studies. The orientational variations of residue fluctuations along the hinge axes in mutant structures justify the existence of coevolution in p1-p6 and NC-p1 substrates, that is, the dynamic behavior of hinge residues should contribute to the interdependent nature of substrate recognition. Overall, this study aids in the understanding of the structural dynamics basis of drug resistance and evolutionary optimization in the HIV-1 protease system

Thermal properties of light tensor mesons via QCD sum rules

The thermal properties of $f_{2}(1270)$, $a_{2}(1320)$ and $K_2^*(1430)$ light tensor mesons are investigated in the framework of QCD sum rules at finite temperature. In particular, the masses and decay constants of the light tensor mesons are calculated taking into account the new operators appearing at finite temperature. The numerical results show that at the point which the temperature-dependent continuum threshold vanishes, the decay constants decrease with amount of $(70-85)\%$ compared to their vacuum values, while the masses diminish about $(60-72)\%$ depending on the kinds of the mesons under consideration. The results obtained at zero temperature are in good consistency with the experimental data as well as existing theoretical predictions.Comment: 11 Pages, 3 Figures and 1 Tabl

Investigating the Effect of Drugs of Chloramphenicol and Gentamicin on Acanthamoeba genotype T3 Causing keratitis Isolated from Environmental samples in vitro

هذه الدراسة هي تحري عن مدى تاثير بعض الادوية على بعض انماط الاكانثاميبا الممرضة المعزولة من المياه العراقية , وذلك لان مشكلة التكيف البيئي الذي يمتاز بها هذا الكائن اضافة الى كونه مستودعا لكثير من الاحياء المجهرية الممرضة التي تحتمي في داخله هربا من المطهرات والادوية يصعب احيانا علاجها بالعلاجات التقليدية . اذ تم جمع نماذج المياه من مناطق مائية مختلفة في العراق وهي بحيرة دوكان ونهر دجلة ونهر الفرات وبحر النجف بواقع 5 نموذج من كل مصدر . وتم عزل الاكانثاميبا من نماذج المياه على اوساط NNA و PYG . استخدم المجهر المقلوب والمجهر الالكتروني لغرض تحديد معالمها المظهرية , كما استخدم تقنية  PCRوSequencing لتحديد نمطها الوراثي , انتمت العزلات الى النمط الوراثي  T3 المتسببة بالالتهابات القرنية  . بعد ذلك ,  تم علاجها في المختبر باستخدام نوعان من الادوية وهما الـ Chloramphenicol و الـ Gentamicin بثلاث تراكيز مختلفة وهي 0.1 % ,0.3  % و 0.6 % وقورنت كفائتهما التثبيطية مع بعضهما و مع السيطرة الموجبة المتمثلة بعقار الكلورهيكسيدين بتركيز  % 0.2 الموصى به في علاج التهاب القرنية الشوكميبي ,  حيث أظهرت النتائج ان كلا الدواءان لهما تأثير تثبيطي  في نمو الاكانثاميبا. , وان دواء الكلورامفينيكول له تاثير اقوى في تثبيط نمو الاكانثاميبا مقارنة بدواء الجنتاميسين وعقار الكلورهيكسيدين , و انه من الممكن عند استخدامه بتركيز معين ان يكون دواءا بديلا في علاج التهاب القرنية الشوكميبي .This study is an investigation of the drugs effect on some pathogenic Acanthamoeba isolated from Iraqi waters, where the problem of environmental adaptation that characterizes this organism in addition to being a reservoir for many pathogenic microorganisms that take shelter in it to escape disinfectants and medicines is sometimes difficult to treat it with traditional treatments.  Twenty water samples were collected from different water regions in Iraq, namely the Dokan Lake, Tigris River, Euphrates River and Najaf Sea, 5 samples from each source.  Acanthamoeba was isolated from water samples on NNA and PYG media, using an inverted microscope with an electron microscope to determine their phenotypic features. PCR and Sequencing were also used to determine their genotype. The isolates were belonged to the T3 genotype that causes corneal infections. Then two types of drugs were used to treat it, which were Chloramphenicol and Gentamicin at three different concentrations, 0.1%, 0.3% and 0.6% and their inhibitory effect was compared with each other and with the positive control of the Chlorohexidine drug at a concentration of 0.2% which was recommended to treat Acanthamoeba keratitis. The results showed that both drugs have an inhibitory effect against Acanthamoeba growth, and that the chloramphenicol had more effect to inhibit compared with gentamicin and chlorhexidine, and it can be used as an alternative treatment instead of chlorohexidine for treating Acanthamoeba keratitis

Tracking MEP installation works

Previous research has shown that "Scan-vs-BIM" systems are powerful to provide valuable information for tracking structural works (progress, quality, safety). However, the transferability of this capability to other construction areas such as MEP works has not been assessed so far. Comparatively, the construction of MEP systems, in particular pipes and ducts, tends to be more flexible with respect to the positioning of individual components, so that Scan-vs-BIM systems could be defeated when tracking MEP installation works. This paper presents recent results on the feasibility and performance of using a Scan-vs-BIM system to track MEP works. The approach followed is presented and then tested with two real-life challenging case studies were conducted simultaneously but totally independently in Canada and Italy. The results show that, as expected, pipes and ducts tend to be more loosely positioned than structural elements leading to a poorer performance of the Scan-vs-BIM system. Nonetheless, it appears that the system works well to assess the level of conformance of site installation works, providing valuable information for estimating emerging performance metrics like "percent built as-designed". In addition, the proposed system could also be useful to accelerate and thus reduce the cost of delivering as-built BIM models for in the case of new builds

A novel difficulty grading system for laparoscopic living donor nephrectomy

Background Several difficulty grading systems have been developed as a useful tool for selecting patients and training surgeons in laparoscopic procedures. However, there is little information on predicting the difficulty of laparoscopic donor nephrectomy (LDN). The aim of this study was to develop a grading system to predict the difficulty of LDN. Methods Data of 1741 living donors, who underwent pure or hand-assisted LDN between 1994 and 2018 were analyzed. Multivariable analyses were performed to identify factors associated with prolonged operative time, defined as a difficulty index with 0 to 8. The difficulty of LDN was classified into three levels based on the difficulty index. Results Multivariable analyses identified that male (odds ratio [OR] 1.69, 95% CI 1.37–2.09, P  28 (OR 1.36, 95% CI 1.08–1.72, P = 0.009), pure LDN (OR 1.99, 95% CI 1.53–2.60, P  Conclusion We developed a novel grading system with simple preoperative donor factors to predict the difficulty of LDN. This grading system may help surgeons in patient selection to advance their experiences and/or teach fellows from simple to difficult LDN

Intensive Care of a Weil's Disease With Multiorgan Failure

Leptospirosis is a commonly encountered type of zoonosis, especially in tropical regions. There is insufficient data regarding its frequency in non-tropical regions such as Turkey. Although leptospirosis presents with a mild icteric form in nearly 90% of cases, it can lead to Weils disease characterized by fever as well as fulminant hepatorenal and respiratory failure, in approximately 5 - 10% of cases. In this case report, we present a patient with Weil's disease, complicated with multiorgan failure

Project Progress Tracking Using Lidar and 4D Design Models

SPR 811Accurate data collected from on-going construction projects assists project field engineers with tracking the progress of construction work. The comparison of as-planned schedules against the as-built status of construction enables the involved parties to determine project performance. Periodic monitoring of project performance enables timely identification of discrepancies between the schedule baseline and project schedule. The rapid identification of discrepancies allows necessary measures to be taken to minimize the impact of a delay on the construction workflow. In transportation projects, the traditional means of acquiring as-built data from a construction site prevents involved parties from receiving the required information from the site in a timely manner. The delay in the communication of information ultimately causes subsequent delays in implementing necessary courses of action targeted toward improving the workflow. Therefore, this project develops a technology-supplemented progress monitoring approach. The technology accurately records as-built data with a high level of detail from a construction worksite within a reasonable period of time using lidar while ensuring the safety of the data collector. The proposed framework utilizes point cloud data obtained using mobile lidar technology and 4D Design Models to identify deviations of the performed work from the planned work. Percentage of Completion (POC) for the as-built bridge elements are calculated and compared with the as-planned POC. The differences between these two POC values for an element, on a particular scan date, are used for assessing the performance of the proposed framework

Successful adult domino living donor liver transplantation in methylmalonic acidemia:case report

Background: Liver transplantation (LT) is a therapeutic option in multiple inherited metabolic diseases (IMDs), including methylmalonic acidemia (MMA), as LT reduces the risk of acute metabolic decompensations and long-term complications associated with these diseases. In certain IMDs, such as maple syrup urine disease (MSUD), domino liver transplant (DLT) is an accepted and safe method which expands the donor pool. However, only one adult case of DLT using an MMA donor liver has been reported; outcome and safety are still unknown and questioned. Case Description: In this case report, we describe our experience with DLT using MMA livers. Two adult MMA patients underwent living donor liver transplant (LDLT); their MMA livers were consecutively transplanted into two patients on the liver transplant waiting list who had limited chance of receiving a liver transplant in the short term due to their low model for end-stage liver disease (MELD) scores. No severe peri- or postoperative complications occurred, however the recipients of the MMA livers biochemically now have mild MMA. Conclusions: DLT using MMA grafts is a feasible strategy to treat end-stage liver disease and expand the donor organ pool. However, the recipient of the MMA domino liver may develop mild MMA which could affect quality of life, and long-term safety remains unclear. Further long-term of outcomes for domino recipients of MMA livers, focusing on quality of life and any metabolic complications of transplantation are needed to better define the risks and benefits