Effects of weight loss on ventricular systolic and diastolic functions and left ventricular mass assessed by tissue doppler imaging in obese geriatric women: preliminary report

Background and aims: Obesity is one of the most common diseases in the world. Particularly in elderly subjects, the effects of weight loss on cardiac functions have not been previously investigated by means of pulsed wave tissue doppler imaging (PWTDI). Using PWTDI, we examined the effects of weight loss on cardiac functions and left ventricular (L V) mass in obese geriatric women. Methods: Thirteen obese women aged 66-83 years (mean age 71.2+/-4.9 yrs) with a body mass index 35.6-49 kg/m(2) (mean body mass index 39.9+/-4.3 kg/m(2)) were evaluated by echocardiography and PWTDI. Only subjects with uncomplicated obesity were included. All measurements, including anthropometric variables, systolic and diastolic indices, and LV Mass, were made before and after a 6-month Orlistat plus hypocaloric diet. Myocardial systolic wave (Sm) velocity, isovolumic acceleration (IVA), myocardial precontraction time (PCTm) and the PCTm to contraction time (CTm) ratio were calculated as systolic indices. Early diastolic wave (Em), late diastolic wave (Am), Em to Am ratio, myocardial relaxation time (RTm), deceleration time (DT) and isovolumic relaxation time (IVRT) were determined as diastolic measurements. Results: Subjects lost an average of 8.4+/-1.2 kg. LV mass decreased significantly after weight loss (p<0.001). In addition, IVRT decreased significantly (p=0.038). Only RTm decreased significantly (p=0.016), whereas other PWTDI parameters of LV remained the same. In the right ventricle, Sm velocity, IVA, Em, and Am velocities were similar. However, the PCTm to Am ratio decreased significantly (p=0.006), and the Em to Am ratio increased (p=0.04) and RTm decreased significantly (p=0.016) after weight loss. Conclusions: In obese geriatric women, weight loss improves ventricular diastolic functions and decreases LV mass. It also contributes to partial improvement in right ventricular systolic function. (Aging Clin Exp Res 2010; 22: 206-211) (C) 2010, Editrice Kurti

Knowledge levels of pulse oximetry usage among pediatricward nurses' and physicians'

Oksijen saturasyonunun sürekli izlenmesi hastanındegerlendirilmesi üzerine önemli etkiler yapmaktadır. Pulse oksimetre ile ilgili bilgi eksikligi saglık profesyonellerinin hasta bakımındaki kararlarını etkileyebilir, yanlıs kararların verilmesine neden olabilir. Bu arastırma, pediatri kliniklerinde çalısan hemsire ve doktorların pulse oksimetre kullanımı ile ilgili bilgi düzeyini belirlemek amacıyla yürütülmüstür. Tanımlayıcı tipteki arastırma, Denizli Devlet Hastanesi, Servergazi Devlet Hastanesi ve Pamukkale ÜniversitesiArastırma ve Uygulama Hastanelerinin pulse oksimetre kullanılan pediatri kliniklerinde yürütülmüstür. Arastırmanın evrenini bu kliniklerde çalısan 61 hemsire ve doktor olusturmustur. Arastırmaya katılmayı kabul eden 48 katılımcı örneklemi olusturmustur. Verilerin toplanmasında arastırmacılar tarafından gelistirilen anket formu kullanılmıstır.Verilerin analizi SPSS 11.0 istatistik programında, sayı-yüzde dagılımları ve testi kullanılarak yapılmıstır. Katılımcıların %75'ini doktorlar, %25'ini hemsireler olusturmustur. Arastırmaya katılan hemsire ve doktorların %29.2'si yenidogan yogunbakım ünitesinde çalısmaktadır. Katılımcıların %60.4'ü pulse oksimetre ile ilgili bir egitim almamıs, bilgileri klinik çalısma sırasında informal egitimle elde ettigini belirtmistir. Pulse oksimetre neyi ölçer sorusuna katılımcıların %85.4'ü dogru cevap vermistir. Pulse oksimetre degerini etkileyen bazı faktörlerle ilgili sorular degerlendirildiginde, katılımcıların %41.7'si tırnak cilasının, %18.8'i aneminin, %22.9'u parlak ısıgın etkisini dogru cevaplamıstır. Katılımcıların %8.3'ü karbonmonoksit zehirlenmesi, %22.9'u kardiyak disritmi durumunda pulse oksimetre degerindeki degisimi dogru cevaplamıstır. Çalısma sonucunda, pediatri kliniklerinde pulse oksimetre ile çalısan hemsire ve doktorların, pulse oksimetre kullanımına ve degerlendirilmesine iliskin ilgi düzeyleri yeterli bulunmamıstır.Continuous monitoring of oxygen saturation has a significant effect on patient assessment. Health care professionals' knowledge deficits on pulse oximetry can affect decisions involving patient care and may cause incorrect decisions. This study was conducted for the purpose of determining the knowledge level about pulse oximetry use of nurses and physicians who work in pediatric wards. This descriptive study was conducted on pediatric wards of Denizli State Hospital, Servergazi State Hospital and Pamukkale University Research and Training Hospital which use pulse oximetry. The research population consisted of 61 nurses and physicians who work on these wards. The study sample was 48 of these who agreed to participate.Aquestionnaire developed by the researchers was used for data collection. Number-percentage distribution and Chi square test were used in the data analysis with the SPSS 11.0 statistical program. Of the participants 75% were physicians and 25% nurses; 29.2% of the participating nurses and physicians worked in newborn intensive care units. The majority (60.4%) of the participants had not received any formal education about the use of pulse oximetry but had been informally trained on its use during clinical practice.To the question about what pulse oximetry is measuring, 85.4% of the participants answered correctly. In the analysis of questions about some factors that can affect pulse oximetry values it was determined that 41.7% correctly answered nail polish, 18.8% anemia, and 22.9% bright light. For conditions which change pulse oximetry values 8.3% correctly answered carbon monoxide poisoning and 22.9% cardiac dysrhythmia. The knowledge level of nurses and physicians working on pediatric wards about the use and evaluation of pulse oximetry is inadequate

The relation between endothelial dependent flow mediated dilation of the brachial artery and coronary collateral development – a cross sectional study

<p>Abstract</p> <p>Background</p> <p>Endothelial dysfunction is thought to be a potential mechanism for the decreased presence of coronary collaterals. The aim of the study was to investigate the association between systemic endothelial function and the extent of coronary collaterals.</p> <p>Methods</p> <p>We investigated the association between endothelial function assessed via flow mediated dilation (FMD) of the brachial artery following reactive hyperemia and the extent of coronary collaterals graded from 0 to 3 according to Rentrop classification in a cohort of 171 consecutive patients who had high grade coronary stenosis or occlusion on their angiograms.</p> <p>Results</p> <p>Mean age was 61 years and 75% were males. Of the 171 patients 88 (51%) had well developed collaterals (grades of 2 or 3) whereas 83 (49%) had impaired collateral development (grades of 0 or 1). Patients with poor collaterals were significantly more likely to have diabetes (<it>p </it>= 0.001), but less likely to have used statins (<it>p </it>= 0.083). FMD measurements were not significantly different among good and poor collateral groups (11.5 ± 5.6 vs. 10.4 ± 6.2% respectively, <it>p </it>= 0.214). Nitroglycerin mediated dilation was also similar (13.4 ± 5.9 vs. 12.8 ± 6.5%, <it>p </it>= 0.521).</p> <p>Conclusion</p> <p>No significant association was found between the extent of angiographically visible coronary collaterals and systemic endothelial function assessed by FMD of the brachial artery.</p

Ocular Vestibular Evoked Myogen&#289;c Potent&#289;al In Adults (Ovemp) Normal Values

Oküler uyarılmış vestibüler miyojenik potansiyel (OVEMP) yakın zamanda tanımlanmış olup, vestibüler hastalıkların ayırıcı tanısında kullanılan yeni bir test tekniğidir. OVEMP non invaziv olarak göz kürelerinin altına inferior oblik kasına yerleştirilmiş yüzeyel elektrotlarla havayolu veya kemikyolu işitme uyaranları kullanılarak kaydedilen kısa latanslı EMG cevaplarıdır. Bu kayıt vestibülo-oküler refleks yoluyla ortaya çıkan ekstra oküler göz kaslarının kasılmasıyla, utrikül ve süperior vestibüler sinir aktivitesini incelemek için kullanılmaktadır. Bu çalışmanın amacı Gazi Üniversitesi Tıp Fakültesi KBB Hastalıkları Anabilim Dalı Odyoloji Bilim Dalı, Prof. Dr. Necmettin Akyıldız &#288;şitme, Konuşma, Ses ve Denge Bozuklukları Tanı, Tedavi ve Rehabilitasyon Merkezinde, ayırıcı tanı testi olarak kullanılmak üzere kulak şikayeti olmayan erişkin ve gönüllü bireylerin normal verilerini elde etmektir. 66 bireyin 132 kulağından elde edilen normal değerleri belirlenmiştir. Bu bulgulara göre N1 latansı 10,44 msn, P1 latansı 15,26 msn N1-P1 amplitüd 9,82 µV, N1-P1 dalga latansı 4,83 msn olarak bulunmuştur. Bütün değerlerin normal dağılıma uydukları ve bir çan eğrisi oluşturdukları görülmüş ve her bir değişken için ±1 ve ±2 SD sınırları belirlenerek tablolar halinde sunulmuştur.Oculer vestibular-evoked myogenic potential (OVEMP) is a technique that is used for diagnosis of vestibular diseases. OVEMP non-invasive as the inferior oblique muscle beneath the eyeball recorded using surface electrodes placed on the bone or air conducted hearing stimuli are short latency EMG responses. This registration with the extra ocular eye muscle contraction occurring through the vestibulo-ocular reflex, utricular and is used to examine the superior vestibular nerve activity. The goal of this study is to record data of adults without hearing complaints in order to be utilized for determinant diagnosis tests aimed to be used at Gazi University Faculty of Medicine, Department of Otolaryngology, Prof. Dr. Necmettin Akyıldız Center of Diagnosis, Treatment and Rehabilitation of Hearing, Speaking, Sound and Balance Disorders. OVEMP values are obtained from 132 ears of 66 participants. The findings reveal that, N1, P1 and N1-P1 latencies are, respectively, 10,44, 15,26 and 4,83 msn, msn N1-P1 amplitude is 9,28 uV. All values have been found to conform to the normal distribution and histogram. For each variable ±1 SD and ±2 SD limits were determined and these were presented in tables

Analysis of inter-rater reliability of the mammography assessment after image processing

3rd International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO) -- APR 15-17, 2015 -- Grenada, SPAINKurt, Burcin/0000-0001-5781-2382WOS: 000410784400008The aim of this study is to assess whether image processing causes information lost on mammography images. in the study, 50 mammogram from MIAS database (open database of mammograms) are selected: 20 images include mass, 20 images include calcification and 10 normal images. Selected images are read and marked by radiologists. the same radiologists read the enhanced version of images after three months later. in order to assess the consistency, inter-rater reliability statistics are used. Results indicate that image processing on mammography images especially images without calcification does not affect radiologists' evaluation consistency. Also, it is indicated that images including calcifications reduce evaluation consistency of the radiologists and it is decided to use other image processing methods for images with calcifications.Univ Granada, CITIC, BioMed Cent, E Hlth Business Dev BULL S A, Univ Granada, Fac Sci, Dept Comp Architecture & Comp TechnolRepublic of Turkey Science, Technology and Industry Ministry; AKGUN Computer Programs and Services Industry Tic. Ltd. StiThe study is a part of a computer-aided breast cancer diagnosis system which is supported as a SANTEZ project by Republic of Turkey Science, Technology and Industry Ministry and AKGUN Computer Programs and Services Industry Tic. Ltd. Sti

Зв’язок фізичної активності та рівня працездатності студентів університету

Background and Study Aim. Physical activity encompasses a range of behaviors across different domains. A critical aspect is the correlation between the frequency of physical activity and perceived competence in these activities. This study aims to explore the relationship between the levels of physical activity and the self-assessed proficiency in physical activities among university students who opt for health-related elective courses. Material and Methods. This study involved 88 university students enrolled in health-related elective courses, including Spinal Health (SH), Posture Disorder (PD), and Physical Activity in Health Promotion (PAHP). Data collection was conducted using the International Physical Activity Questionnaire-Short Form (IPAQ-SF) and the Physical Activity Efficacy Scale (PAES) surveys. For data analysis, one-way analysis of variance (ANOVA) and the Tukey test, a Post-hoc multiple comparison method, were employed. Results. The study revealed a weak negative correlation between IPAQ-SF and PAES scores. This indicates that as self-confidence and sense of competence increased, the level of physical activity decreased (p&lt;0.05). Participants in the PAHP course exhibited higher levels of physical activity, as reflected in their PAES scores, compared to those enrolled in the SH course (p&lt;0.05). Despite having a lower average income, students in the PAHP course demonstrated higher physical activity levels than those in other courses. Conclusions. The study demonstrated that as levels of physical activity efficacy increase, actual physical activity levels decrease, and vice versa. Furthermore, students enrolled in PAHP courses exhibited improved physical activity scores compared to those in other courses. It was also concluded that the income level of students does not significantly impact their level of physical activity.Передумови та мета дослідження. Фізична активність охоплює низку видів поведінки в різних областях. Критичним аспектом є кореляція між частотою фізичної активності та передбачуваною компетентністю в цій діяльності. Це дослідження має на меті дослідити взаємозв’язок між рівнями фізичної активності та самооцінкою рівня фізичної активності серед студентів університетів, які обирають факультативні курси, пов’язані зі здоров’ям.Матеріал і методи. У цьому дослідженні взяли участь 88 студентів університету, які навчаються на факультативних курсах, пов’язаних зі здоров’ям, зокрема «Здоров’я хребта» (ЗХ), «Порушення постави» (ПД) і «Фізична активність у зміцненні здоров’я» (ФЗД). Збір даних проводився за допомогою Міжнародної короткої форми опитувальника щодо фізичної активності (IPAQ-SF) і опитування Шкали ефективності фізичної активності (PAES). Для аналізу даних використовували односторонній дисперсійний аналіз (ANOVA) і тест Тьюкі, метод множинного порівняння Post hoc.Результати. Дослідження виявило слабку негативну кореляцію між балами IPAQ-SF і PAES. Це свідчить про те, що зі зростанням впевненості в собі та почуття компетентності рівень фізичної активності знижувався (p&lt;0,05). Учасники курсу PAHP продемонстрували вищий рівень фізичної активності, що відображено в їхніх балах PAES, порівняно з тими, хто навчався на курсі SH (p&lt;0,05). Незважаючи на нижчий середній дохід, студенти курсу PAHP продемонстрували вищі рівні фізичної активності, ніж студенти інших курсів.Висновки. Дослідження показало, що зі збільшенням рівня ефективності фізичної активності фактичні рівні фізичної активності знижуються, і навпаки. Крім того, студенти, які навчаються на курсах PAHP, продемонстрували кращі показники фізичної активності порівняно з тими, хто навчався на інших курсах. Також було зроблено висновок, що рівень доходів студентів суттєво не впливає на рівень їх фізичної активності

Can We Determine The Time Elapsed Until The Birth In Preterm Premature Rupture Of Membranes (Pprom) And Preterm Labor (Pte) ? [Preterm Prematur Erken Membran Rupturu (Pprom) Ve Preterm Eylem (Pte)De Doguma Kadar Gecen Sureyi Belirleyebilir Miyiz?]

We aimed to determined; affect of clinical, laboratory, and ultrasonographic factors the time elapsed until the birth in midtrimester PPROM and PTE. Total 448 PPROM and PTE patients were conceived which applicant the Perinatology Department of zekai Tahir Burak Women's Health Education And Research Hospital between 2012-2014 years. PPROM group consisted of 237 patients, PTE group consisted of 211 patients. PPROM and PTE groups were divided into subgroups as cervical culture positive and negative PPROM and PTE groups. Risk factors of until the time of birth was determined by multivariate regression analysis in cervical culture positive PPROM and PTE groups. Cervical length measured by TVUSG=0,907, 95% Cl = 0,823-0,999 (p=0,047) and amniotic fluid index (or= 0,962, 95% Cl= 0,946-0,980 (p [Med-Science 2016; 5(2.000): 468-83

A new seasonal fuzzy time series method based on the multiplicative neuron model and SARIMA

When fuzzy time series include a seasonal component, conventional fuzzy time series models are not sufficient. For such fuzzy time series, lagged variables which are around the period of the time series should also be included in the model. Determining the lagged variables which will be in the forecasting model is a vital issue. Also, defining fuzzy relations is another important issue in the fuzzy time series approach. When the number of fuzzy lagged variables is large, using artificial neural networks to define fuzzy relations makes the operations easier and increases the forecasting accuracy. In this study, in order to deal with the problem of determining the lagged variables, and defining the fuzzy relations, a novel seasonal fuzzy time series approach based on SARIMA and the multiplicative neuron model is proposed. In the proposed method, the SARIMA method is exploited to choose the fuzzy lagged variables and multiplicative neuron model is employed to establish the fuzzy relations. To show the applicability of the proposed method, it is applied to the invoice sum accrued to health service providers. For comparison, the data is also analyzed with other fuzzy time series approaches in the literature. It is observed that the proposed method has the best forecasting accuracy with respect to other methods