394 research outputs found

    From risk-based health surveillance to health promotion: an evidence-based experience in a health care setting.

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    Health surveillance’s aim consists in different aspects: (i) to ensure worker’s health, (ii) to comply regulation, (iii) to detect health changes at their onset, (iv) to reduce cost, (v) to provide a fitness for job judgement, (vi) to provide a medical baseline and (vii) to be part of a preventive programme. Some of these aspects are perceived as benefits from the different stakeholders. Employers indicated as benefits worker’s satisfaction improvement, cost reduction, relationship improvement, early detection of health changes5. The study showed some other benefits: an improvement in worker’s satisfaction, an improvement in the relationship between stakeholders (even though based on qualitative data only), an early detection of health changes in few cases and a sickness absence reduction after influenza vaccination programme

    Nuove applicazioni per le unità abitative in emergenza: tecnologie e tecniche della tradizione costruttiva andina amazonica

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    This work reports the result of a research activity conducted in Bolivia in the year 2020, in synergy between Bolivian Polytechnic University School "Josè Maria Nunez del Prado", University of Naples Federico II and Pegaso Telematic University. In particular, the research had as its object the study of a housing unit suitable for coping with the floods that frequently afflict some Bolivian peasant populations. During the research, much attention was initially paid to the historical, political, socio-economic aspects and to the cultural and traditional characteristics of the ethnic groups that make up the population of Bolivia; subsequently, the morphology and hydrography of the Bolivian territory were examined, as well as the climate, the trend of rainfall and the El Niño and La Niña phenomena that often cause floods with serious risks for the populations, especially rural ones. Having completed these first two phases of the research, the authors moved on to the study of the traditional construction characteristics of rural architecture, paying particular attention to the basic construction materials used in the peasant areas of Bolivia, in particular to raw earth and bamboo, as well as the principles and rules that regulate the construction of rural housing in Bolivia. For rural architecture, the traditional Pawichi house and the traditional dwellings of the indigenous Chiquitana population were examined in detail. Only after having acquired all these important aspects, the research became interested in the design of a new rural house which, respecting Bolivian cultural traditions, would be able to cope with floods and reduce the risks associated with them. In the design of this new emergency housing unit, the authors focused their attention not only on the compositional and functional aspects of the housing unit, but also on the constructive aspects by designing new structural elements such as the pillars made with five bamboo canes suitably linked together. with knots of the Andean construction tradition. The composition of the housing unit proposed by the authors is governed by a basic 4x4 module that can be full, or delimited by infill and window frames, or empty, or without surrounding infill elements to allow the creation of the traditional place for socialization, the Punilla. Never as in this case have, I been particularly happy with the invitation formulated by the authors, and in particular by the young researchers, Francesca Volpe and Emanuele La Mantia, to present their work. In fact, I was able to see the procedural quality of the research and the intelligent design procedure that led to the definition of a housing prototype of great interest for the Andean populations

    The Grizzly, October 1, 1982

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    Professors Leave on Sabbatical • New Record Breaker Theme is Photograph • McNamara Displays Hoop Skill • Letter to a Confused Freshman • Ursinus Welcomes New Dean • Letters to the Editor • Opinion: Campus Crime has got to Stop! • It Takes a Trained Eye • GOP\u27s Strategy in \u2782 • The Who Rock JFK • Magnificent Noise • Roving Reporter: What do You Consider to be the Most Positive Aspect of Ursinus College? • I\u27m Turning Japanese • Field Hockey Team Wins 5th Straight • 1982 Ursinus Grizzly Football Stats • Grizzlies Capture First Win! • Grizzlies to Play in Newly Formed Conference • X-Country Streak Broken • Soccer Suffers Setback • Girls\u27 Volleyball Lose Twohttps://digitalcommons.ursinus.edu/grizzlynews/1083/thumbnail.jp

    The Grizzly, September 24, 1982

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    Crime Comes to Collegeville: Attempted Assault on Main Street • New Advising System for Freshmen Students • Union Program Board Projects VCR Movies • McNamara to Speak at Ursinus Gym • What? More New Faculty? • Speech Exemption Exam Set • Writing Center Opens • Time for Action • Name That Tune! • In the Limelight • USGA Notes • Forum Review • Kohler Exhibits at Myrin • Brown Sets X-country Record • Volleyball Team Keeps Their Winning Ways • Field Hockey Tops Gettysburg in O.T. • U.C. Soccer Wins Their First • Grizzlies Look Tough in 6-6 Tiehttps://digitalcommons.ursinus.edu/grizzlynews/1082/thumbnail.jp

    A new hexapeptide from the leader peptide of rMnSOD enters cells through the oestrogen receptor to deliver therapeutic molecules

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    A 24-amino acid leader peptide of a new human recombinant manganese superoxide dismutase can enter cells and carry molecules. Here, we demonstrated that six of the 24 amino acids penetrate cells through a particular gate represented by a specific amino acid sequence of the oestrogen receptor (ER). We analysed the internalization of the synthetic hexapeptide and the cytotoxic activity of the hexapeptide conjugated to cisplatin on a cell line panel. In most cell lines, the hexapeptide delivered an amount of cisplatin that was 2 to 8 times greater than that released by cisplatin when the drug was used alone. This increased delivery increases the therapeutic index of cisplatin and reduces side effects caused by a high dosage or long-term treatment times. We may consider this hexapeptide a new molecular carrier to deliver molecules with therapeutic activity into ER+ cells for diagnostic purposes and clinical or immune therapy
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