130 research outputs found
Student’s Learning Profile as a Tool of Personal Learning Logistics
Increase of complexity and uncertainty as well as demand for personalization (including in education) urges universities to pay attention to educational subjectivity and its development; to transfer towards individual / collective-individual educational navigation and flexible systems of educational programs management (including formation of temporary learning groups, supply of required educational resources in due time, protocols of appraisal and mutual offset of educational results), what determines the relevance of the research. Usage of logistic approach enables to distinguish the pedagogical and management objectives of educational activity organization as well as to facilitate personalization of education. The article considers an educational profile as an instrument of personal educational logistics in digital educational environment, presents the preliminary terms “digital track”, “portfolio”, “profile”. The authors also dwell on the requirements to educational profiles development and scenarios of handling them in digital educational environment taking into account domestic and global experience of educational profiles’ implementation
Long-term results of treatment of right-sided colon cancer with mesocolic excision and D3-lymph node dissection
Aim of investigation. To estimate efficacy of D3-lymph node dissection with mesocolic excision in comparison to standard surgical technique of right hemicolectomy for right colon cancer in long-term terms.Methods. Comparative analysis of the long-term results of treatment of right colon cancer at I–III stages with D2- and D3-lymph node dissections was carried out. Traditional right hemicolectomy with D2-lymph node dissection was applied in 132 patients (control group). Patients after right hemicolectomy with D3-lymph node dissection, mesocolic excision with «notouch» principles have been included to the main group (n=64). Groups were comparable by demographic and clinical features, and also by stage of local neoplastic spread.Results. Significant differences in general cumulative 5-years survival rate (69 and 86% respectively, р=0,043) and 5-years cancer-specific survival rate (91 and 71% respectively, р=0,014) have been revealed between control and main groups. Among patients with involved lymph nodes (III stage) overall 5-years survival rate after standard surgery (58%) was worse, than after right hemicolectomy with D3-lymph node dissection (83%, p=0,042). In patients with D2-lymph node dissection the involvement of regional lymph nodes was significant prognostic factor deteriorating overall 5-years survival rate (p=0,039) while at D3-lymph node dissection this factor had no effect on the prognosis (p=0,535).Conclusion. At right colon cancer of I–III stages D3-lymph node dissection is the major factor significantly improving overall 5-years survival rate. Extended lymph node dissection is the factor levelling negative prognostic effect of metastatic lymph node involvement which can be accomplished by prevention of local lymphogenic relapse of tumor
An introduction to description logics and query rewriting
This chapter gives an overview of the description logics underlying the OWL 2 Web Ontology Language and its three tractable profiles, OWL 2 RL, OWL 2 EL and OWL 2 QL. We consider the syntax and semantics of these description logics as well as main reasoning tasks and their computational complexity. We also discuss the semantical foundations for fist-order and datalog rewritings of conjunctive queries over knowledge bases given in the OWL2 profiles, and outline the architecture of the ontology-based data access system Ontop
Follicular Occlusion Syndrome — a Possible Option of Follicular-Retension Origin of Pilonidal Sinus
Аim: to analyze and evaluate the clinical and morphological manifestations of pilonidal sinus disease (PSD) as a part of follicular occlusion syndrome (FOS).Materials and methods. In the Clinic of Coloproctology and Minimally Invasive Surgery, 80 patients with PSD underwent surgeries from November 2018 to December 2019: 62 (77.5 %) patients — with primary PSD, 18 (22.5 %) — with recurrence of the disease.Results. There were 80 patients, 6 patients (9.7 %) with primary and one (5.6 %) patient with recurrent cyst had concomitant manifestations of follicular occlusion syndrome. Thus, the frequency of combination of PSD with other variants of FOS course amounted to 8.8 %. Hidradenitis suppurativa of axillary and inguinal areas was found in 5 out of 7 patients. Acne conglobata, as one of the components of FOS, was noted in three patients. Dissecting cellulitis of the scalp was diagnosed in one patient. Follicular occlusion triad was observed in two patients. Follicular occlusion tetrad was not noted in any observation. All patients were treated with excision of the pilonidal sinus disease with local tissue-plasty of the defect. At present, no recurrences have been noted in any of the cases, and the mean follow-up time was 14 ± 5.6 months (6–27 months). PSD as a manifestation of follicular occlusion syndrome is characterized by a more cranial and more superficial location of the cavity in the sacrococcygeal region. According to the data of histologic examination of patients with FOS, the morphologic picture is identical with patients with isolated PSD. All patients with confirmed FOS have received pathogenetic local and conservative therapy. After the therapy remission of combined diseases is noted.Conclusion. Deroofing of the lining of the cavity, often used in dermatologic practice, along with complex treatment within the framework of multidisciplinary (together with a dermatologist) management of patients with FOS, looks promising
General Terminology Induction in OWL
Abstract. Automated acquisition, or learning, of ontologies has attracted re-search attention because it can help ontology engineers build ontologies and give domain experts new insights into their data. However, existing approaches to on-tology learning are considerably limited, e.g. focus on learning descriptions for given classes, require intense supervision and human involvement, make assump-tions about data, do not fully respect background knowledge. We investigate the problem of general terminology induction, i.e. learning sets of general class in-clusions, GCIs, from data and background knowledge. We introduce measures that evaluate logical and statistical quality of a set of GCIs. We present methods to compute these measures and an anytime algorithm that induces sets of GCIs. Our experiments show that we can acquire interesting sets of GCIs and provide insights into the structure of the search space.
Thermophysical properties of the fe48cr15mo14c15b6y2 alloy in liquid state
In this work, the physical properties of Fe48Cr15Mo14C15B6Y2 alloy in liquid state at high temperature are studied. It was observed that the basic physical characteristics of the alloy, such as viscosity, electrical resistivity, and density, decrease with an increase of the temperature to 1700◦C. An abnormal increasing rate of viscosity for Fe48Cr15Mo14C15B6Y2 alloy in the temperature range from 1360 to 1550◦C was noted. The measurement of the electrical resistivity and density did not reveal any anomalies in the same temperature range. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.This research was funded by of the Ministry of Science and Higher Education of the Russian Federation in the framework of the Increase Competitiveness Program of NUST «MISiS» (grant number K2-2020-046). V.S.T., V.V.K. and V.V.V gratefully acknowledge the financial support made within the framework of state work No. FEUZ-0836-0020. Also, D.S.K. and J.V.I. gratefully acknowledge the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 897815 NanoSurf
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology
<p>Abstract</p> <p>Background</p> <p>Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity and robustness. The richness in bio-ontologies is a prior condition for diverse and efficient reasoning, and hence querying and hypothesis validation. Rigour allows a more consistent maintenance. Modelling such bio-ontologies is, however, a difficult task for bio-ontologists, because the necessary richness and rigour is difficult to achieve without extensive training.</p> <p>Results</p> <p>Analogous to design patterns in software engineering, Ontology Design Patterns are solutions to typical modelling problems that bio-ontologists can use when building bio-ontologies. They offer a means of creating rich and rigorous bio-ontologies with reduced effort. The concept of Ontology Design Patterns is described and documentation and application methodologies for Ontology Design Patterns are presented. Some real-world use cases of Ontology Design Patterns are provided and tested in the Cell Cycle Ontology. Ontology Design Patterns, including those tested in the Cell Cycle Ontology, can be explored in the Ontology Design Patterns public catalogue that has been created based on the documentation system presented (<url>http://odps.sourceforge.net/</url>).</p> <p>Conclusions</p> <p>Ontology Design Patterns provide a method for rich and rigorous modelling in bio-ontologies. They also offer advantages at different development levels (such as design, implementation and communication) enabling, if used, a more modular, well-founded and richer representation of the biological knowledge. This representation will produce a more efficient knowledge management in the long term.</p
Diagnostics and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, the Russian Society of Colorectal Surgeons, the Russian Endoscopic Society and the Scientific Society for the Clinical Study of Human Microbiome)
Aim. The guidelines set out the modern methods of diagnostics and treatment of peptic ulcer and are created for gastroenterologists, primary care physicians, general practitioners, surgeons, endoscopists.Key points. The clinical guidelines contain modern views on the etiology and pathogenesis of peptic ulcer, its clinical features, methods of laboratory and instrumental diagnostics, the main approaches to conservative and surgical treatment. They include the criteria for assessment of the quality of medical care, the algorithm of the doctor's actions, as well as information for the patient.Conclusion. Knowledge of modern methods of diagnostics and therapy of peptic ulcers will contribute to improving the results of its treatment
Obstructed defaecation syndrome: European consensus guidelines on the surgical management.
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