212 research outputs found

    E-textbooks and connectivity: proposing an analytical framework

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    This paper is concerned with the development of e-textbooks. We claim that analysis (and design) of e-textbooks requires the development of a specific frame. Digital affordances provide particular opportunities (e.g. in terms of interactions between users) that require specific considerations for their analysis, as teachers and students use them for their individual and collective purposes. In this study, we develop a framework for mathematics e-textbook analysis, based on the notion of “connectivity.” We introduce criteria to assess the different aspects of connectivity and build an analysis grid for e-textbooks. We illustrate the framework proposed by analyzing 2 commonly used French grade 10 mathematics e-textbooks. The results of the analyses show that there are major differences between the 2 e-textbooks in terms of connectivity, which can be related to differences in their design. Beyond these 2 examples, we claim that focusing on connectivity is a useful and relevant way of analyzing e-textbooks, as it can provide a window into issues of interactivity, both practically and cognitively

    Le sorgho

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    Denrée alimentaire de base et source importante de nourriture pour les animaux, le sorgho est cultivé dans les zones arides, semi-arides et tempérées. Totalement illustré, ce livre porte sur tous les aspects de la culture du sorgho (biologie, génétique et vulnérabilité face aux animaux nuisibles) et sur ses fonctions écologiques. Son texte révisé et mis à jour décrit également les systÚmes de récolte et la transformation pour la consommation humaine

    Giving new sorghum variety options to resource-poor farmers in Nicaragua through participatory varietal selection

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    In the dry areas of Nicaragua, white-grain sorghum is an important subsistence crop for resource-poor farmers. From 2002 to 2007, participatory varietal selection (PVS) was implemented in three regions with the aim of identifying new varieties matching small farmers' needs. This paper describes the general approach, the partnership and the methods used to identify farmers' selection criteria (FSC), as well as the evaluation of new germplasm using the scoring method. Data analysis involved relating farmers' evaluation data to agronomic data and farmers' selection decisions (FSD), using Spearman correlations and the chi-square test. In the three regions, higher grain yield and good grain quality for making tortillas were identified as the two main FSCs for both the 'tortillero' and 'millĂłn' sorghum types; the ranking of the other important FSC differed between the sites and the sorghum types. Our data shows that farmers' scores for earliness were highly correlated with breeder's observations while farmers' assessments of grain yield were correlated with measured yield in half the cases, depending on their knowledge of the crop. The study shows that in evaluating grain quality the farmers used several specific traits which were not considered by breeders. Overall appreciation, grain yield and grain quality were the key farmers' criteria that contributed to FSD. The PVS work enabled breeders to obtain a better understanding of farmers' criteria as well as identifying new progenitors, which should be useful for the sorghum breeding schemes in Central America in the future. Furthermore, by exploring wide genetic diversity, it was possible to release several farmer-preferred and high-performing varieties within a fairly short period

    New sources of resistance to sorghum midge in Burkina Faso

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    New sources of midge (Stenodiplosis sorghicola) resistance among local Sorghum bicolor cultivars were determined in experiments carried out from 1996-99 in Burkina Faso. Two hundred local landraces from Burkina Faso and other West African countries were screened for midge resistance. The 40 best cultivars were tested with resistant and susceptible controls during the 1999 rainy seasons, in midge-infested sites Kouaré and Farako-Bù. The average percentage of midge-damaged spikelets in Kouaré varied from 0% in ICSV 745 to 45.3% in susceptible landrace 439. At Farako-Bù, the percentage of damaged spikelets varied from 0.4% in ICSV 745 to 31.8% on the susceptible control Sariaso 10. Cultivar Tenlopieno had the highest percentage of damaged spikelets in both locations, but showed low visual midge damage scores

    Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate

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    Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease among the elderly. To understand pathogenesis and to test therapies, animal models that faithfully reproduce key pathological PD hallmarks are needed. As a prelude to developing a model of PD, we tested the tropism, efficacy, biodistribution, and transcriptional impact of canine adenovirus type 2 (CAV-2) vectors in the brain of Microcebus murinus, a nonhuman primate that naturally develops neurodegenerative lesions. We show that introducing helper-dependent (HD) CAV-2 vectors results in long-term, neuron-specific expression at the injection site and in afferent nuclei. Although HD CAV-2 vector injection induced a modest transcriptional response, no significant adaptive immune response was generated. We then generated and tested HD CAV-2 vectors expressing LRRK2 (leucine-rich repeat kinase 2) and LRRK2 carrying a G2019S mutation (LRRK2G2019S), which is linked to sporadic and familial autosomal dominant forms of PD. We show that HD-LRRK2G2019S expression induced parkinsonian-like motor symptoms and histological features in less than 4 months

    Bridging knowing and proving in mathematics An essay from a didactical perspective

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    Text of a talk at the conference "Explanation and Proof in Mathematics: Philosophical and Educational Perspective" held in Essen in November 2006International audienceThe learning of mathematics starts early but remains far from any theoretical considerations: pupils' mathematical knowledge is first rooted in pragmatic evidence or conforms to procedures taught. However, learners develop a knowledge which they can apply in significant problem situations, and which is amenable to falsification and argumentation. They can validate what they claim to be true but using means generally not conforming to mathematical standards. Here, I analyze how this situation underlies the epistemological and didactical complexities of teaching mathematical proof. I show that the evolution of the learners' understanding of what counts as proof in mathematics implies an evolution of their knowing of mathematical concepts. The key didactical point is not to persuade learners to accept a new formalism but to have them understand how mathematical proof and statements are tightly related within a common framework; that is, a mathematical theory. I address this aim by modeling the learners' way of knowing in terms of a dynamic, homeostatic system. I discuss the roles of different semiotic systems, of the types of actions the learners perform and of the controls they implement in constructing or validating knowledge. Particularly with modern technological aids, this model provides a basis designing didactical situations to help learners bridge the gap between pragmatics and theory

    How an improved sorghum variety evolves in a traditional seed system in Mali: Effects of farmers’ practices on the maintenance of phenotype and genetic composition

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    In Africa, it is mostly the informal seed system that ensures farmers’ seed supply. This is partly because the formal seed systems are not always effective in meeting demand for new seed varieties. Sometimes informal seed recycling and exchange of improved sorghum varieties will take place alongside formal initiatives, as is the case in southern Mali. Focusing on one particular village in the Dioïla district, we analyze the efficacy of farmers’ strategies for preserving varietal seed purity and genetic integrity of an improved inbred-line (Soumba variety). Six seed lots of Soumba, recycled for two to six years by farmers using different practices, were collected and assessed in on-station trials in order to compare their agronomic performance and phenotypic purity (off-type plant frequencies) with control versions of the variety. Additionally, 30 panicle samples were randomly collected from five farmer fields sown with recycled Soumba and assessed for phenotypic purity in a progeny nursery and investigated for molecular diversity using 12 SSR markers. A total of 150 panicles from five other non-Soumba varieties were collected in the village in order to investigate eventual gene flow and its potential genetic consequences for the Soumba variety. In fields sown with recycled Soumba seed, between 2% and 14% of plants showed phenotypic deviations from the typical Soumba variety. The progeny nursery and SSR marker analysis verified the presence of the off-type plants observed in the field. The STRUCTURE program revealed admixtures with other varieties in 23% of Soumba plants, confirming the presence of gene flow. Gene diversity values in Soumba samples ranged from 0.006 for the commercial sample to 0.257 for recycled samples. Introgression and contamination were best minimized when (1) farmers had received specific training in seed production, (2) they could take advantage of isolated fields and (3) they could practise true-to-type panicle selection. Farmerswere generally able to maintain the phenotype, as well as sustain or even improve yield performance of their Soumba variety while at the same time genetically enriching their seed stock

    Helping farmers adapt to climate and cropping system change through increased access to sorghum genetic resources adapted to prevalent sorghum cropping systems in Burkina Faso

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    Sorghum (Sorghum bicolor (L.) Moench) is a major staple crop of Burkina Faso where farmers continue to cultivate photoperiod-sensitive guinea landraces as part of the strategy to minimize risk and ensure yield stability. In the Boucle du Mouhoun region, however, sorghum farmers appear to have insufficient varietal choice due to cropping systems having shifted towards more intensive cultivation of cotton and maize, and rainfall patterns having decreased over the past decade. In search for new varietal options that can respond to this changing context, researchers decided to give farmers access to ex-situ national collections along with the opportunity to evaluate recent improved varieties. From 2002 to 2007, researchers and farmers worked closely together to implement on-farm testing, including varietal selection trials, crop management and multi-locational trials. Farmers’ choices tend to differ among groups, villages and years, with the exception of four particular landraces: two originating from a collection carried out in the Mouhoun region more than 30 years previous to this research, and two other landraces that came from the dissimilar agro-ecological zones of Burkina Faso. These four were the most commonly selected landraces out of 36 cultivars that covered both improved and landrace varieties. Farmers’ selection criteria were focused on adaptation to agro-climatic conditions as well as specific grain qualities for processing and consumption. The potential usefulness of each variety was verified via multi-locational trials. The paper also shows that wide dissemination of experimental seed, not just across the Mouhoun region but also at a national scale, was largely achieved through collaboration with a strong farmer organisation in conjunction with farmer training programs focused on the on-farm seed production and the commercialisation of this seed

    Characterization of semi-arid Chadian sweet sorghum accessions as potential sources for sugar and ethanol production

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    Sweet sorghum (Sorghum bicolor (L.) Moench) is an important crop in Chad that plays an economic role in the countryside were stalks are produced mainly for human consumption without any processing. Unfortunately, very little information exists on its genetic diversity and brix content. Studies performed in 2014 and 2015 showed that there were significant variations (p < 0.001) for all assessed quantitative traits. Potential grain yield (0.12–1.67 t ha−1), days to 50% flowering (68.3–126.3 days), and plant height (128.9–298.3 cm) were among traits that exhibited broader variability. Brix content range from 5.5 to 16.7% across accessions, was positively correlated to stalk diameter and plant height, but negatively correlated to moisture content in fresh stalk and potential grain yield. Fresh stalk yield range from 16.8 to 115.7 Mg ha−1, with a mean value of 58.3 Mg ha−1 across accession. Moisture content in fresh stalk range from 33.7 to 74.4% but was negatively correlated to fresh stalk yield. Potential sugar yield range from 0.5 to 5.3 Mg ha−1 across accession with an average of 2.2 Mg ha−1. Theoretical ethanol yield range from 279.5 to 3,101.2 L ha−1 across accession with an average of 1,266.3 L ha−1 which is significantly higher than values reported under similar semiarid conditions. Overall, grain yields were comparatively low. However, two accessions had grain yield of more than 1.5 t ha−1; which is greater than the average 1.0 t ha−1 for local grain sorghum varieties in Chad. These could have multi-purpose uses; grains, sugar and bioenergy production
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