Storm-time changes of geomagnetic field at MAGSAT altitudes (325-550 Km) and their comparison with changes at ground locations

The values of H, X, Y, Z at MAGSAT altitudes were first expressed as residuals delta H, delta X, delta Y, delta Z after subtracting the model HMD, XMD, YMD, ZMC. The storm-time variations of H showed that delta H (Dusk) was larger (negative) than delta H (Dawn) and occurred earlier, indicating a sort of hysteresis effect. Effects at MAGSAT altitudes were roughly the same (10% accuracy) as at ground, indicating that these effects were mostly of magnetospheric origin. The delta Y component also showed large storm-time changes. The latitudinal distribution of storm-time delta H showed north-south asymmetries varying in nature as the storm progressed. It seems that the central plane of the storm-time magnetospheric ring current undergoes latitudinal meanderings during the course of the storm

Development of Zwitterionic Hydrophilic Liquid Chromatography (ZICⓇHILIC-MS) metabolomics method for Shotgun analysis of human urine

Urine is a product of the body’s metabolism and the majority of the metabolic products exiting via the renal system are rendered polar in order to be water soluble. Resolution of urinary metabolites for metabolomic studies requires the development of HPLC separation techniques that match this feature of biological chemistry. ZIC –HILIC is an ideal candidate to take forward resolution of such metabolites where reverse phase is unable to give adequate separation. Metabolomic data has to be processed by Shotgun multivariate analysis to sift through thousands of analytes and their variables such as ion intensity. In the development of ZIC-HILIC separation with mass spectrometric (IT-ToF) detection, methodological variability have to be minimized so that any Shotgun data analysis does not reveal potential biomarker analytes that are artifacts or are adversely affected of the separation and detection technique. Here, we report the development of a ZIC-HILIC mass spectrometry method that is suitable for SIMCA P+ data analysis of urine. Variables such as resolution, run reproducibility and sample storage temperature were evaluated in tandem with SIMCA P+ data analysis and quality control pre-processing. The developed method couples quality control runs that pre-process and exclude analytes that are insufficiently robust for further candidate biomarker studies. This meant labile analytes that could not be reproduced in 70% of QC runs (which are pools of all samples run that day) were excluded. However, urine samples stored at 4°C for more than 9 months will contain metabolites that will alter and produce small molecule marker artifacts when compared to samples stored at -20°C. In conclusion, the developed method is a robust method of ZIC-HILIC mass spectrometry shotgun analysis suitable for urinary metabolome discovery of robust biomarkers

Convergence Guarantees for Discrete Mode Approximations to Non-Markovian Quantum Baths

Non-Markovian effects are important in modeling the behavior of open quantum systems arising in solid-state physics, quantum optics as well as in study of biological and chemical systems. The non-Markovian environment is often approximated by discrete bosonic modes, thus mapping it to a Lindbladian or Hamiltonian simulation problem. While systematic constructions of such modes have been previously proposed, the resulting approximation lacks rigorous and general convergence guarantees. In this letter, we show that under some physically motivated assumptions on the system-environment interaction, the finite-time dynamics of the non-Markovian open quantum system computed with a sufficiently large number of modes is guaranteed to converge to the true result. Furthermore, we show that this approximation error typically falls off polynomially with the number of modes. Our results lend rigor to classical and quantum algorithms for approximating non-Markovian dynamics

Results of an aqueous source term model for a radiological risk assessment of the Drigg LLW Site, U.K.

A radionuclide source term model has been developed which simulates the biogeochemical evolution of the Drigg low level waste (LLW) disposal site. The DRINK (DRIgg Near field Kinetic) model provides data regarding radionuclide concentrations in groundwater over a period of 100,000 years, which are used as input to assessment calculations for a groundwater pathway. The DRINK model also provides input to human intrusion and gaseous assessment calculations through simulation of the solid radionuclide inventory. These calculations are being used to support the Drigg post closure safety case. The DRINK model considers the coupled interaction of the effects of fluid flow, microbiology, corrosion, chemical reaction, sorption and radioactive decay. It represents the first direct use of a mechanistic reaction-transport model in risk assessment calculations

Interface Pattern Selection Criterion for Cellular Structures in Directional Solidification

The aim of this investigation is to establish key scientific concepts that govern the selection of cellular and dendritic patterns during the directional solidification of alloys. We shall first address scientific concepts that are crucial in the selection of interface patterns. Next, the results of ground-based experimental studies in the Al-4.0 wt % Cu system will be described. Both experimental studies and theoretical calculations will be presented to establish the need for microgravity experiments

Cosmologies with Null Singularities and their Gauge Theory Duals

We investigate backgrounds of Type IIB string theory with null singularities and their duals proposed in hep-th/0602107. The dual theory is a deformed N=4 Yang-Mills theory in 3+1 dimensions with couplings dependent on a light-like direction. We concentrate on backgrounds which become AdS_5 x S^5 at early and late times and where the string coupling is bounded, vanishing at the singularity. Our main conclusion is that in these cases the dual gauge theory is nonsingular. We show this by arguing that there exists a complete set of gauge invariant observables in the dual gauge theory whose correlation functions are nonsingular at all times. The two-point correlator for some operators calculated in the gauge theory does not agree with the result from the bulk supergravity solution. However, the bulk calculation is invalid near the singularity where corrections to the supergravity approximation become important. We also obtain pp-waves which are suitable Penrose limits of this general class of solutions, and construct the Matrix Membrane theory which describes these pp-wave backgrounds.Comment: 43 pages REVTeX and AMSLaTeX. v2: references adde

Successful long distance road transport of green mussel from Calicut to port Okha.

The seeds of green mussel were collected from coastal areas at Elathur (north of Calicut) in the morning hours of 26-11-'83, and after cleaning them thoroughly with sea water, without any prior conditioning, were kept in HDPE tanks of about 300-400 litre capacity. A total of 9,000 seeds were thus collected and transported to Port Okha, The journey started from Calicut on 26-ll-'83 at 1000 hrs and ended at Port Okha on l-12-'83 at 0230 hrs covering a linear distance of 2,300 km. The average size was 24.4 mm in length, 4.6 g in wet weight, 12.8 mm in width and 7.7 mm in breadth, and the transport used was a closed body insulated 10 tonner truck. Water was not changed during the entire journey period from Calicut to Okha. The experience gained in the process of transportation can go a long way in mass transplantation of mussel seeds or allied fish/shellfish seeds in the future

Primordial Magnetic Field Limits from Cosmic Microwave Background Bispectrum of Magnetic Passive Scalar Modes

Primordial magnetic fields lead to non-Gaussian signals in the cosmic microwave background (CMB) even at the lowest order, as magnetic stresses and the temperature anisotropy they induce depend quadratically on the magnetic field. In contrast, CMB non-Gaussianity due to inflationary scalar perturbations arises only as a higher order effect. Apart from a compensated scalar mode, stochastic primordial magnetic fields also produce scalar anisotropic stress that remains uncompensated till neutrino decoupling. This gives rise to an adiabatic-like scalar perturbation mode that evolves passively thereafter (called the passive mode). We compute the CMB reduced bispectrum ($b_{l_{_1}l_{_2}l_{_3}}$) induced by this passive mode, sourced via the Sachs-Wolfe effect, on large angular scales. For any configuration of bispectrum, taking a partial sum over mode-coupling terms, we find a typical value of $l_1(l_1+1)l_3(l_3+1) b_{l_{_1}l_{_2}l_{_3}} \sim 6-9 \times 10^{-16}$, for a magnetic field of $B_0 \sim 3$ nG, assuming a nearly scale-invariant magnetic spectrum . We also evaluate, in full, the bispectrum for the squeezed collinear configuration over all angular mode-coupling terms and find $l_1(l_1+1)l_3(l_3+1) b_{l_{_1}l_{_2}l_{_3}} \approx -1.4 \times 10^{-16}$. These values are more than $\sim 10^6$ times larger than the previously calculated magnetic compensated scalar mode CMB bispectrum. Observational limits on the bispectrum from WMAP7 data allow us to set upper limits of $B_0 \sim 2$ nG on the present value of the cosmic magnetic field of primordial origin. This is over 10 times more stringent than earlier limits on $B_0$ based on the compensated mode bispectrum.Comment: 9 page