Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Search for Exclusive Charmless B Meson Decays with the DELPHI Detector at LEP

Charmless hadronic decays of beauty mesons have been searched for using the data collected with the DELPHI detector at the LEP collider. Several two, three and four-body decay modes have been investigated. Particle identification was used to distinguish the final states with protons, kaons and pions. Three candidate events selected in two-body decay modes are interpreted as evidence for charmless B decays. No excess has been found in higher multiplicity modes and improved upper limits for some of the branching ratios are given.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe

A measurement of the photon structure function F2γ_{2}^{\gamma} at an average Q2^{2} of 12 GeV2^{2}/c4^{4} : results from DELPHI

The hadronic photon structure function F_{2}^{\gamma} has been measured in the Q^{2} range from 4 to 30~GeV^2/c^{4} and down to x values of order 0.001, using data taken with the DELPHI detector at LEP between 1991 and 1993. A comparison is made with several F_{2}^{\gamma} parameterizations with special emphasis on their low x behaviour. A result on the Q^{2} evolution of F_{2}^{\gamma} is presented