Designing a Ring Oscillator Using Nanotechnology through Cadence Virtuoso

This paper presents the design and simulation of a ring oscillator using nanotechnology and the Cadence Virtuoso platform. As feature sizes continue to shrink, new design methodologies are required to account for quantum effects that become prominent at the nanoscale. This paper utilizes predictive technology models for a 45nm process to design a three-stage ring oscillator with minimum channel lengths. The ring oscillator design is optimized through careful selection of transistor characteristics and layout considerations. Post-layout simulations demonstrate functionality with oscillation frequency and phase noise matching expected theoretical values. The completed design provides a demonstration of a basic analog circuit block implemented with nanoscale technology. &nbsp

Raga Therapy An Effective Treatment for Stress Management

Delayed encounters with stress are identified with poor individual well-being and related to significant monetary expenses for the general public. Accordingly, the advancement of cost-effective stress prevention or stress management tactics has turned into a vital attempt at recent research endeavors. Music has been appeared to influence physiological, cognitive, and emotional stress-related procedures advantageously. Subsequently, the utilisation of tuning in to music as a financial, non-intrusive, and profoundly acknowledged mediation apparatus has gotten uncommon enthusiasm for the administration of stress and stress-related medical problems. “Raga is the grouping of chosen notes (swaras) that loan suitable ‘temperament’ or feeling in a specific blend. “Raga therapy means healing through the raga. It’s a yoga framework with the help of resonant sounds. Ragatherapy implies curing through the raga. It is the information on the most proficient method to utilise raga for curing [1]”. Symphonies of raga ensure a calming influence on the mind and body. Researchers have found the role of raga therapy in treating stress. In the present research, raga therapy was administered to 74 subjects suffering from stress as an intervention plan. The ISMA questionnaire was administered to them before and after the intervention. Different sequences of ragas were directed to them for 30 min. A significant effect of raga therapy established on stress management

A study on chromium accumulation in Labeo rohita in the river Yamuna ecosystem in Mathura-Agra region in Uttar Pradesh, India

Abstract: The present study revealed the chromium toxicity and its health measures in L. rohita from the Yamuna river at Mathura- Agra region. Samples were taken in triplicate from both sites i.e. Vrindavan (Bihar ghat) and Agra (Renuka Ghat). The study was carried out on Four different organs (i.e. gills, muscles, liver, and kidney) of the fish sample. The sampling was done from Oct 2018 to January 2020. Chromium concentration in different organs of the fish was analyzed by Atomic absorption spectrophotometer(AAS). The average Cr concentration in gills was highest (9.64  mg/l) at the Mathura site followed byAgra sites (7.78 mg/l) for the month of April 2019. The concentration of Cr was highest in samples taken in the month of April 2019 and it was lowest in October 2018. The significantly high Cr concentration values were observed in the Mathura region than the Agra region for both seasons. In all samples, Cr concentration was above the standards stated by WHO except in the Kidney. In the present study, the bioaccumulation factor showed the chromium concentration in the tissues followed the order of gill > liver > muscle > kidney. HPI, MQI, and Pearson’s correlation coefficient analysis were also done in which HPI was observed very high and there was a positive correlation between all the samples.   Keywords:  Chromium, BCF, HPI, MQI, AAS, Fish Organ

Married women migrating from rural Uttar Pradesh and Bihar: juggling family duty and aspirations

This article traces the experiences of accompanying wives who had migrated with their husbands from southern Bihar and Uttar Pradesh and returned to their villages during the COVID-19 pandemic. It dwells on post-marriage migration and work which is an under-researched aspect of women’s migration. Our study offers insights into the ways in which married women navigate power relations within the family as well as their places of work to fulfil their family obligations and personal aspirations. The analysis shows how they juggle multiple family roles as wives, mothers, daughters-in-law and daughters in their decisions related to (im)mobility, work and earning. Theoretically, the article speaks to the production of gendered and racialised work and how these fit into capitalist accumulation, women’s productive and reproductive labour, and the tensions between family duties and personal aspirations. The women in the study were ‘factory’ workers, home-based workers and ‘homeworkers’, all with different subjectivities. Although women’s work and mobility are shaped by patriarchal norms in both states, the women in our study were pushing the boundaries of tradition and asserting their views within the family. Work in cities has given them the means of fulfilling aspirations, especially related to their children’s education

EFFECT OF PREVIOUS SCORPION BITE ON THE EFFICACY OF INTRATHECALLY ADMINISTERED LEVOBUPIVACAINE IN SUBARACHNOID BLOCK

Objectives: Local anesthetics administered by spinal anesthesia acts through sodium channels. Mutations of sodium channels may be responsible for resistance to local anesthetic agents. The scorpion venom contains neurotoxins that block the sodium channels. In view of the high prevalence of scorpion stings in our region and observation of failure of spinal anesthesia in patients with a history of scorpion stings in routine practice, the present study is planned. Methods: Forty patients of the American Society of Anesthesiologists Grade I or II who were undergoing infraumbilical surgery were divided into two groups as S (patients with h/o scorpion bite) and C (patients with no such history). The subarachnoid block was given with 3.2 ml of injection Levobupivacaine 0.5% heavy using 26 gauzes Quincke spinal needle. A blind observer recorded a sensory block using a needle prick and a motor block using the Bromage scale. Onset of sensory and motorized block, time to peak of sensory, and motor block and its relation to number of scorpion bites were observed in both the groups. Results: The onset of sensory (2.61±1.68 mins) and motor blockade (2.91±1.80 mins) was significantly delayed in Group S (p=0.010 and 0.004, respectively). Time to peak of sensory and motor blockade was also prolonged in Group S (6.45±2.83 mins and 7.8±3.95 mins) compared to Group C (3.60±0.84 mins and 4.56±1.30 mins) which was statistically significant (p<0.05). Patients who had previous scorpion bites (Group S) had a significant failure rate of spinal anesthesia compared to the control group. Conclusion: In this study, it was observed that the patients with scorpion bites had a significant failure rate of spinal anesthesia, suggesting probable resistance to the local anesthetic agents

Productivity of Milch Animals in Small Scale Dairying among Female and Male Headed Households

ABSTRAC

Bioactive compounds and therapeutic properties of Aloe vera- a review

Aloe vera is a popular herbal medicine and worldwide appreciated for its therapeutic potential. From ancient time, it has been used as a home remedy for different health issues. Many researchers have shown its therapeutic potential and there are many citations of characterization of bioactive compounds from it. A wide range of bioactive compounds have been characterized from Aloe vera. It has a wide range of antimicrobial, antioxidant, and antidiabetic properties. Aloe vera can also provide support for carbohydrate and lipid metabolism by maintaining the level of cholesterol and sugar in blood and it can also help to maintain body weight. Due to the presence of higher number of bioactive compounds and prolific therapeutic properties, it is widely used in medicine, cosmetics and food sector. In this review, the characterisation of bioactive compounds from Aloe vera along with the extraction of its gel and encapsulation is reviewed with a discussion on its medicinal properties

Ondansetron exposure during pregnancy is not associated with risk of congenital malformations: evidence from a meta-analysis

Ondansetron is widely used drug for treatment of morning sickness and hyperemesis gravidarum. However, whether exposure to ondansetron during pregnancy is associated with risk of congenital malformations or not remains debatable. The present meta-analysis was performed for published cohort/registry-based studies which evaluated the association between ondansetron exposure and risk of congenital malformations. Major congenital malformations were considered as the primary outcome measure. Specific abnormalities like cardiac malformation, septal defect, cleft lip/palate, hypospadias, and genitourinary abnormalities were considered as secondary outcome measures along with spontaneous abortion/miscarriage, stillbirth, preterm delivery, and low birth weight babies. Pooled analysis was done using the Mantle-Hanzle method, random effect model and were expressed as odds ratio (OR) with 95% CI. Fourteen studies were included in systematic review. There was no significant difference for major congenital malformations [n=12; OR: 1.12 (95% CI: 0.93-1.36), I2=96], septal defect [n=5; OR: 1.39 (95% CI: 1.01-1.91), I2=48%], cleft lip/palate [n=3; OR: 1.11 (95% CI: 0.80-1.53), I2=41%] between ondansetron exposed and control arms. However, a greater number of events were found in control arm than intervention arm for cardiac defect [n=7; OR: 1.26 (95% CI: 1.09-1.45), I2=71%; p=0.002]. We also observed a greater number of events for stillbirth and pre-term labour in control arm than in intervention arm with OR: 1.57 (95% CI: 1.24-1.97); p=0.0001 and OR: 1.33 (95% CI: 1.05-1.69); p=0.02, respectively. This meta-analysis concludes that ondansetron exposure during pregnancy is not associated with any increased risk of major congenital malformations, septal /cardiac defect, cleft lip/palate, spontaneous abortion/miscarriage, stillbirth, pre-term labour and low birth weight babies

Middleware Architecture - History and Adaptation with IEEE 802.11

Communication, which intends to provide a link between any two people, is now moving towards man-to-machine and machine-to-machine connection for transferring different types of data. This transmission scenario, with and ever expanding number of active and passive users, lays the foundation to variety of communication protocols owing to the different types of data which is involved in the process. Within this ever expanding communication arena, Middle-ware can be thought of as a set of hardware and software which is used to connect different platforms with the end-users that are increasing in number day-by-day, with a possible wide spread over any region spanning from few meters to several kilometers. IEEE 802.11 is the set of standards which guides the wireless technology for device implementation and demands seamless integration across the entire protocol stack. This in turn demands an overview of the middleware architecture in broader perspective. This chapter explores the concept of middleware in the existing communication scenario, current trends and future scope