43 research outputs found
Single-dose pharmacokinetic study comparing the pharmacokinetics of recombinant human chorionic gonadotropin in healthy Japanese and Caucasian women and recombinant human chorionic gonadotropin and urinary human chorionic gonadotropin in healthy Japanese
Soluble tumor necrosis factor (TNF) receptor‐1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor‐β1
Positivo en dopaje por exceso de beta-HCG secundario a seminoma testicular: a propósito de un caso
Treatment of active Crohn's disease with onercept (recombinant human soluble p55 tumour necrosis factor receptor): results of a randomized, open-label, pilot study
Gene Therapy of Collagen-Induced Arthritis by Electrotransfer of Human Tumor Necrosis Factor- α
Parallel nocturnal secretion of melatonin and testosterone in the plasma of normal men
Differences and similarities in the temporal organization of hormone secretion in plasma reflect the activity of CNS pacemakers. One aspect of this activity, the temporal synchronization of the secretion of different hormones is still poorly understood. We report the analysis of melatonin and testosterone plasma concentrations during two nights in 6 normal healthy young men. Blood was collected every 20 min between 2040 and 0640. Plasma testosterone concentrations increased by 1.5- to 2- fold during the second part of the night, and melatonin by 2.5-to 4-fold. In each subject. the individual temporal pattern of melatonin was quite stable over the two nights of sampling. while testosterone profiles showed fluctuations. There was a high degree of parallelism in these two hormones nocturnal secretion. These results, together with previous studies, suggest that melatonin might entrain the nocturnal secretion of testosteron