Nuevos nematicidas: valoración de residuos de la producción semiindustrial de aceites esenciales

PublishedEste trabajo ha sido financiado por fondos de del MINECO al Proyecto CTQ2012-38219-C03-0

Peroxidase expression in a cereal cyst nematode (Heterodera avenae) resistant hexaploid wheat line.

The incompatible interaction between plant and pathogen is often determined by the hypersensitive reaction (HR). This response is associated with accumulation of reactive oxygen species (ROS), which results in adverse growth conditions for pathogens. Two major mechanisms involving either NADPH oxidases or peroxidases have been proposed for generation of ROS. Peroxidases (PER, EC 1.11.1.7), present in all land plants, are members of a large multigenic family with high number of isoforms involved in a broad range of physiological processes. PER genes, which are expressed in nematode feeding sites, have been identified in several plant species (Zacheo et al. 1997). A strong correlation between HR and PER activities at four and seven days post nematode infection, was detected in roots of wheat lines carrying Cre2, Cre5 (from Ae. ventricosa) or Cre7 (from Ae. triuncialis) Heterodera avenae resistance genes (Andrés et al. 2001; Montes et al. 2003, 2004). We have studied changes in root of peroxidase mRNAs levels after infection by H. avenae of a wheat/Ae. ven¬tricosa introgression line (H-93-8) carrying Cre2 (Delibes et al. 1993). We also report and classify the predicted protein sequences derived from complete peroxidase transcripts

Effectiveness of a mental health stepped-care programme for healthcare workers with psychological distress in crisis settings: a multicentre randomised controlled trial

The dataset that supports the findings of this study are available upon reasonable request at the Universidad Autónoma de Madrid data repository, e‐cienciaDatos in https://doi.org/10.21950/HN1HNOArtículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMEvidence-based mental health interventions to support healthcare workers (HCWs) in crisis settings are scarce. Objective To evaluate the capacity of a mental health intervention in reducing anxiety and depression symptoms in HCWs, relative to enhanced care as usual (eCAU), amidst the COVID-19 pandemic. Methods We conducted an analyst-blind, parallel, multicentre, randomised controlled trial. We recruited HCWs with psychological distress from Madrid and Catalonia (Spain). The intervention arm received a stepped-care programme consisting of two WHO-developed interventions adapted for HCWs: Doing What Matters in Times of Stress (DWM) and Problem Management Plus (PM+). Each intervention lasted 5 weeks and was delivered remotely by non-specialist mental health providers. HCWs reporting psychological distress after DWM completion were invited to continue to PM+. The primary endpoint was self-reported anxiety/depression symptoms (Patient Health Questionnaire-Anxiety and Depression Scale) at week 21. Findings Between 3 November 2021 and 31 March 2022, 115 participants were randomised to stepped care and 117 to eCAU (86% women, mean age 37.5). The intervention showed a greater decrease in anxiety/depression symptoms compared with eCAU at the primary endpoint (baseline-adjusted difference 4.4, 95% CI 2.1 to 6.7; standardised effect size 0.8, 95% CI 0.4 to 1.2). No serious adverse events occurred. Conclusions Brief stepped-care psychological interventions reduce anxiety and depression during a period of stress among HCWs. Clinical implications Our results can inform policies and actions to protect the mental health of HCWs during major health crises and are potentially rapidly replicable in other settings where workers are affected by global emergenciesThe RESPOND project was funded by the European Commission under Horizon 2020 - the Framework Programme for Research and Innovation (2014– 2020) (grant number: 101016127). The work of RM was funded by the State Plan for Scientific and Technical Research and Innovation 2021–2023 of the Spanish Agencia Estatal de Investigación (FJC2021-047610-I), the Acción Estratégica en Salud programme of the Instituto de Salud Carlos III (CD22/00061), and the Centro de Investigación Biomédica en Red (CB/07/09/0013). The work of MF-N was funded by the Acción Estratégica en Salud programme of the Instituto de Salud Carlos III (CD20/00036

Characterization of the Chilean Public Procurement Ecosystem Using Social Network Analysis

Indexación: Scopus.'Mercado Público' is a Chilean electronic platform used for purchasing processes by Chilean public organizations for the last two decades. The main aim of this study is to characterize the Chilean public procurement ecosystem by using social network analysis to detect the main communities of suppliers based on who awarded the tenders. To do this, we use a methodology that first represents the bidder-supplier relationship as a bipartite graph using purchase order information. Then we project the bipartite graph onto a monopartite graph of suppliers. We end by detecting the main supplier communities using a modularity algorithm. When we applied this methodology to the large tender segment in the Chilean public procurement market over a period of four years, we successfully detected the five largest communities and the micro and small companies which had the greatest rate of participation over time.https://ieeexplore.ieee.org/document/914958

Reproductive Biology of Common Small Pelagic Fishes in Manila Bay, Philippines

Reproductive biology of the three dominant species (Sardinella gibbosa, Sardinella fimbriata, and Rastrelliger kanagurta) were studied in Manila Bay from January 2014 to December 2015. The data were collected from landed catch (coming from gillnet, lift net, purse seine, ringnet, and trawl) and during the actual trawl fishing survey. A total of 2,383 Sardinella gibbosa, 2,334 Sardinella fimbriata, and 549 Rastrelliger kanagurta were analyzed by pooling the two years data. The overall female to male ratio conformed to the expected 1:1 sex ratio. These species spawn throughout the year with major peak in March and April and minor peak in October to December for Sardinella gibbosa; with major peak in February to May and minor peak in October to December for Sardinella fimbriata; and for Rastrelliger kanagurta, with major peak in October to December and minor peak in May and June. The GSI values correlate with the maturation of the gonads of these species. The length at maturity (Lm50) was calculated at 12.75 cm in males and 13.25 cm in females for S. gibbosa; 12.25 cm in males and 12.75 cm in females for S. fimbriata; and 25.5 cm in males and 24.5 cm in females for R. kanagurta

Equation of state for hot dense matter using a relativistic screened hydrogenic model

The study of matter under conditions of high density, pressure, and temperature is a valuable subject for inertial confinement fusion (ICF), astrophysical phenomena, high-power laser interaction with matter, etc. In all these cases, matter is heated and compressed by strong shocks to high pressures and temperatures, becomes partially or completely ionized via thermal or pressure ionization, and is in the form of dense plasma. The thermodynamics and the hydrodynamics of hot dense plasmas cannot be predicted without the knowledge of the equation of state (EOS) that describes how a material reacts to pressure and how much energy is involved. Therefore, the equation of state often takes the form of pressure and energy as functions of density and temperature. Furthermore, EOS data must be obtained in a timely manner in order to be useful as input in hydrodynamic codes. By this reason, the use of fast, robust and reasonably accurate atomic models, is necessary for computing the EOS of a material

L’Artritis reumatoide

Treballs d'Educació Farmacètica als ciutadans. Unitat Docent d'Estades en Pràctiques Tutelades. Facultat de Farmàcia, Universitat de Barcelona. Curs: 2014/2015, Tutors: David Berlana Martin, Ignasi Cardona Pascual i Marian March Pujol.L’artritis reumatoide és una malaltia autoimmunitària que afecta a tots els grups poblacionals, i que cursa amb inflamació de les articulacions. La seva etiologia és encara desconeguda, fet que provoca que sigui un camp d’interès actual d’investigació. El tractament de primera línia consisteix en l’administració d’antiinflamatoris, analgèsics i/o corticoides, per tal de calmar el dolor i controlar la inflamació. A més s’afegeix FAME’s per alentir la progressió de la malaltia. Si amb aquest tractament no és suficient per mantenir un control, es passa al de segona línia que consisteix en l’administració d’anticossos monoclonals (teràpia biològica). Amb l’elaboració d’aquest treball i la realització de les activitats proposades, hem aplicat el rol de farmacèutic en l’educació ciutadana, proporcionant informació als malalts d’artritis per tal de promoure la seva salut. Cal destacar la importància que no només el pacient, sinó també el seu entorn familiar coneguin les característiques i evolució de la malaltia, amb l’objectiu de millorar la qualitat de vida dels malalts

Detailed-level-accounting approach calculation of radiative properties of aluminium plasmas in a wide range of density and temperature

In this work it is accomplished a study of radiative properties of aluminium plasmas. It is analyzed the calculation of spectrally resolved and mean opacities both under NLTE and LTE approaches. Furthermore, the effect of the re-absorption of the radiation in these magnitudes is also examined. The calculations were performed into the detailed-levelaccounting approach including configuration interaction among the levels belonging to the same non-relativistic configuration

Analysis of the influence of the plasma thermodynamic regime in the spectrally resolved and mean radiative opacity calculations of carbon plasmas in a wide range of density and temperature

In this work the spectrally resolved, multigroup and mean radiative opacities of carbon plasmas are calculated for a wide range of plasma conditions which cover situations where corona, local thermodynamic and non-local thermodynamic equilibrium regimes are found. An analysis of the influence of the thermodynamic regime on these magnitudes is also carried out by means of comparisons of the results obtained from collisional-radiative, corona or Saha–Boltzmann equations. All the calculations presented in this work were performed using ABAKO/RAPCAL code

Determination of level populations and radiative properties of optically thin and thick carbon plasmas

In several research fields of current interest such as astrophysics or inertial fusion confinement the knowledge of the interactions between the photons and the plasma particles, i.e. plasma radiative properties, result essential. Thus, for example, the understanding of these plasmas requires properties such as emissivities and opacities both for hydro-simulations and diagnostics. Carbon is one of the most interesting elements under investigation, since it is likely to be a major plasma-facing wall component in ITER, and it plays a major role in inertial fusion scenarios. Also, some laser experiments have focused on the spectrally resolved emission from hydrocarbon systems. Therefore, radiative properties from carbon plasmas must be known and, as a consequence, the theoretical study of these plasmas is a subject of current interest and many efforts are headed. In particular, recent NLTE workshops have focused on comparisons of modelling calculations for specific cases that allow testing the models since there are very few experimental measurements for carbon plasmas. For these reasons it is interesting to characterize them in a wide range of plasma conditions. In a previous work we carried out an exhaustive study of optically thin carbon plasmas under steady state condition in a wide range of electron densities and temperatures given by (1-200) eV and (10 12 -10 22 ) cm -3 respectively [1], where CE, NLTE or LTE regimes are achieved. In this work we analyse the reabsorption radiation effects for homogeneous carbon plasmas in planar geometry by means of the escape factor formalism. We focus our attention on the average ionization and ionic populations as well as the multifrequential and mean opacity. All the calculations presented in this work were performed by using ABAKO code [1] which integrates the RAPCAL code [2] in order to calculate optical properties for a wide range of temperatures and electron number densitie