Valor del índice de resistencia arterial medido por Doppler en la función del injerto renal a mediano y largo plazos

Objective: To evaluate the association between the value of the arterial resistance index (RI) measured by Doppler at the month after transplantation, and the loss of graft. Secondary outcomes of loss greater than or equal to 50% of renal function, eath with functioning graft, biopsy findings (inflammation, hyalinosis, rejection, interstitial fibrosis - tubular atrophy, IFTA) are reported. Methods: A cohort study of 66 patients, who underwent renal transplantation at San José Hospital of Bogotá between October 2007 and April 2011. The RI of the hilar artery was measured by Doppler ultrasound at the month post-transplant. Most patients had follow-up until the second year. We describe the cumulative incidence of renal graft loss, loss greater than or equal to 50% of the glomerular filtration rate. At the second year after transplantation, rejection, IFTA, hyalinosis and documented inflammation were reported in protocol biopsies. Association analysis was performed on the histological outcomes. Results: only 2 cases of renal graft loss were reported, belonging to the group with normal RI (3.8%). At 3 years of follow-up, 5 patients had lost more than 50% of GFR compared to baseline, 4 occurred in patients with RI <0.8, 2 of them (3.7%) ocurred in the first year and only one patient with RI> 0.8 ocurred at 3 years. The median GFR at 3 years of follow-up in both groups is greater than 60 ml / min. In the first year of follow-up 22 (47%) patients with normal RI had IFTA, and 7 (54%) with RI> 0.8 had IFTA. Hyalinosis was reported for 23% with RI> 0.8 and 25.5% with RI <0.8. Conclusion: the outcome of the grafts depends not only on RI, but also on factors such as cold ischemia, induction and maintenance immunosuppressive treatment, degree of incompatibility between donor and recipient. Histopathological changes such as IFTA, inflammation, hyalinosis, were observed in both groups, suggesting that there are other factors stronger than the RI, which correlates with the occurrence of these findings.Objetivo: evaluar la asociación entre el valor del índice de resistencia arterial (IR) medido por doppler al mes postrasplante y la pérdida de injerto. Se reportan los desenlaces secundarios de pérdida mayor o igual al 50% de la función renal, muerte con injerto funcionante, hallazgos de la biopsia (inflamación, hialinosis, rechazo, fibrosis intersticial - atrofia tubular, IFTA, por sus siglas en inglés). Métodos: se realizó un estudio de cohorte de 66 pacientes, que recibieron trasplante renal, del Hospital San José de Bogotá, entre octubre de 2007 y abril de 2011; se midió el IR de la arteria hilar por ecografía doppler al mes postrasplante. La mayoría de los pacientes fueron seguidos hasta el segundo año. Se describe la incidencia acumulada de pérdida del injerto renal, pérdida mayor o igual al 50% de la tasa filtración glomerular; al segundo año postrasplante se reporta el rechazo, IFTA, hialinosis e inflamación documentada en las biopsias de protocolo. Se realizó análisis de asociación en los desenlaces histológicos. Resultados: solo se reportaron 2 casos de pérdida del injerto renal, pertenecientes al grupo con IR normal (3.8%). A los 3 años de seguimiento 5 pacientes habían perdido más del 50% de la TFG respecto a la basal, 4 ocurrieron en los pacientes con IR <0.8, 2 de ellos (3.7%) fueron al primer año y solo un paciente con IR >0.8 a los 3 años. La mediana de la TFG a los 3 años de seguimiento en ambos grupos es mayor de 60 ml/ min. En el primer año de seguimiento 22 (47%) pacientes con IR normal presentaron IFTA y 7 (54%) con IR >0.8 presentaron IFTA; la hialinosis con un 23% para IR >0.8 y 25.5% para IR <0.8. Conclusión: los desenlaces de los injertos no solo dependen del IR, hay otros factores que pueden influir como es el tiempo de isquemia fría, esquema de tratamiento inmunosupresor de inducción y mantenimiento, grado de incompatibilidades entre donante, receptor. Cambios histopatológicos como IFTA, inflamación, hialinosis, se observaron en cualquiera de los 2 grupos, lo que sugiere que hay otros factores más fuertes que el IR, que se correlaciona con la aparición de estos hallazgos

PRODUCCIÓN DE TOMATE EN INVERNADERO CON COMPOSTA Y VERMICOMPOSTA COMO SUSTRATO

The organic production of food is an alternative for consumers that prefer food free of pesticides, synthetic fertilisers, and with a high nutritional value. The purpose of this study was to evaluate substrates prepared with mixtures of compost and vermicompost with sand, at various levels, under greenhouse conditions. The tomato hybrid SUN-7705 (Lycopersicon esculentum Mill) was analized in four substrates that included compost and vermicompost mixed at three different proportions (100, 75 y 50 %). The treatments were distributed in a completely randomised design with a factorial arrangement of 4x3 and five replicates. The greatest average yield (39.811 t ha) was obtained with the compost generated by decomposing bovine manure, corn stover (Zea mays L.), elephant grass (Pennisetum purpureum Schumacher) and black earth (CEMZT) at 75% + sand, and with the vermicompost generated by manure, bahiagrass (Paspalum notatum Flügge) and black earth (VEPT) at 100 and 50% + sand. This yield was greater than that recorded for organic tomato production in the field, without affecting the quality of the fruit

Correlation between obesity and severity of distal radius fractures

Introduction: The incidence of obesity has increased significantly worldwide. Our hypothesis was that patients with obesity have a more severe distal radius fracture and we realized a study to evaluate this correlation between obesity and severity of distal radius fractures caused by low-energy injuries. Materials and methods: A total of 114 patients with distal radius fracture were examined in

Maternal dietary patterns and acute leukemia in infants: results from a case control study in Mexico

BackgroundChildhood cancer is the leading cause of disease-related mortality among children aged 5–14 years in Mexico, with acute leukemia being the most common cancer among infants. Examining the overall dietary patterns allows for a comprehensive assessment of food and nutrient consumption, providing a more predictive measure of disease risk than individual foods or nutrients. This study aims to evaluate the association between maternal dietary patterns during pregnancy and the risk of acute leukemia in Mexican infants.MethodsA hospital-based case–control study was conducted, comparing 109 confirmed acute leukemia cases with 152 age-matched controls. All participants (≤24 months) were identified at hospitals in Mexico City between 2010 and 2019. Data on a posteriori dietary patterns and other relevant variables were collected through structured interviews and dietary questionnaires. Multivariate logistic regression was employed to estimate the association between maternal dietary patterns during pregnancy and the risk of acute leukemia in infants.ResultsThe “Balanced & Vegetable-Rich” pattern, characterized by a balanced consumption of various food groups and higher vegetable intake, exhibited a negative association with acute leukemia when compared to the “High Dairy & Cereals” Pattern (adjusted odds ratio [OR] = 0.51; 95% confidence interval [CI]: 0.29, 0.90). We observed that mothers who gave birth to girls and adhered to a healthy dietary pattern during pregnancy exhibited significantly lower odds of their children developing AL compared to those who gave birth to boys [OR = 0.32 (95% CI 0.11, 0.97)]. Our results underscore the significance of maternal nutrition as a modifiable factor in disease prevention and the importance of prenatal health education

Proyecto Binacional México-España: “Promoviendo y Generando Competencias Digitales para los Profesionales de la Salud”

Póster y vídeo presentados al 22 Congreso Nacional de Hospitales y Gestión Sanitaria celebrado en Málaga el 15-17 de septiembre de 2021Esta investigación ha sido apoyada por beca de la Fundación Pública Andaluza Progreso y Salud, y Fundación FIMABIS, Consejería de Salud de la Junta de Andalucía (EF-0401-2019).YesEsta propuesta se fundamenta en la premisa del Ministerio de Educación del Gobierno de España, la Unión Europea y la UNESCO, donde afirma que, la mayoría del personal de Salud debe reforzar sus habilidades digitales de consulta para mejorar sus buenas prácticas

Transformación digital y formación en competencias. Un proyecto de innovación educativa España-México

Póster y vídeo presentados al VI Congreso Internacional y XII Nacional de la Asociación de Enfermería Comunitaria (AEC). VIII Encuentro Nacional de Tutores y Residentes de Enfermería Familiar y Comunitaria celebrado en Sevilla 27, 28 y 29 de octubre de 2021Esta investigación ha sido apoyada por becas de la fundación pública Andaluza Progreso y Salud, y fundación FIMABIS, Consejería de Salud de la Junta de Andalucía (EF-0401-2019).YesLa crisis sanitaria y el distanciamiento social impuesto por la pandemia, ha puesto en evidencia la urgente necesidad que tienen los profesionales de adquirir competencias digitales, que les faculte para atender las tareas de éstos en el nuevo ecosistema de la información y la comunicación en la actual Sociedad del Conocimiento

Patients with Crohn's disease have longer post-operative in-hospital stay than patients with colon cancer but no difference in complications' rate

BACKGROUNDRight hemicolectomy or ileocecal resection are used to treat benign conditions like Crohn's disease (CD) and malignant ones like colon cancer (CC).AIMTo investigate differences in pre- and peri-operative factors and their impact on post-operative outcome in patients with CC and CD.METHODSThis is a sub-group analysis of the European Society of Coloproctology's prospective, multi-centre snapshot audit. Adult patients with CC and CD undergoing right hemicolectomy or ileocecal resection were included. Primary outcome measure was 30-d post-operative complications. Secondary outcome measures were post-operative length of stay (LOS) at and readmission.RESULTSThree hundred and seventy-five patients with CD and 2,515 patients with CC were included. Patients with CD were younger (median = 37 years for CD and 71 years for CC (P < 0.01), had lower American Society of Anesthesiology score (ASA) grade (P < 0.01) and less comorbidity (P < 0.01), but were more likely to be current smokers (P < 0.01). Patients with CD were more frequently operated on by colorectal surgeons (P < 0.01) and frequently underwent ileocecal resection (P < 0.01) with higher rate of de-functioning/primary stoma construction (P < 0.01). Thirty-day post-operative mortality occurred exclusively in the CC group (66/2515, 2.3%). In multivariate analyses, the risk of post-operative complications was similar in the two groups (OR 0.80, 95%CI: 0.54-1.17; P = 0.25). Patients with CD had a significantly longer LOS (Geometric mean 0.87, 95%CI: 0.79-0.95; P < 0.01). There was no difference in re-admission rates. The audit did not collect data on post-operative enhanced recovery protocols that are implemented in the different participating centers.CONCLUSIONPatients with CD were younger, with lower ASA grade, less comorbidity, operated on by experienced surgeons and underwent less radical resection but had a longer LOS than patients with CC although complication's rate was not different between the two groups