1,189 research outputs found
Inferring undesirable behavior from P2P traffic analysis
While peer-to-peer (P2P) systems have emerged in popularity in recent years, their large-scale and complexity make them difficult to reason about. In this paper, we argue that systematic analysis of traffic characteristics of P2P systems can reveal a wealth of information about their behavior, and highlight potential undesirable activities that such systems may exhibit. As a first step to this end, we present an offline and semi-automated approach to detect undesirable behavior. Our analysis is applied on real traffic traces collected from a Point-of-Presence (PoP) of a national-wide ISP in which over 70% of the total traffic is due to eMule, a popular P2P file-sharing system. Flow-level measurements are aggregated into "samples" referring to the activity of each host during a time interval. We then employ a clustering technique to automatically and coarsely identify similar behavior across samples, and extensively use domain knowledge to interpret and analyze the resulting clusters. Our analysis shows several examples of undesirable behavior including evidence of DDoS attacks exploiting live P2P clients, significant amounts of unwanted traffic that may harm network performance, and instances where the performance of participating peers may be subverted due to maliciously deployed servers. Identification of such patterns can benefit network operators, P2P system developers, and actual end-user
Diploptene δ13C values from contemporary thermokarst lake sediments show complex spatial variation
Cryospheric changes in northern high latitudes are linked to significant greenhouse gas flux to the atmosphere, for example, methane that originates from organic matter decomposition in thermokarst lakes. The set of pathways that link methane production in sediments, via oxidation in the lake system, to the flux of residual methane to the atmosphere is complex and exhibits temporal and spatial variation. The isotopic signal of bacterial biomarkers (hopanoids, e.g. diploptene) in sediments has been used to identify contemporary ocean-floor methane seeps and, in the geological record, periods of enhanced methane production (e.g. the PETM). The biomarker approach could potentially be used to assess temporal changes in lake emissions through the Holocene via the sedimentary biomarker record. However, there are no data on the consistency of the signal of isotopic depletion in relation to source or on the amount of noise (unexplained variation) in biomarker values from modern lake sediments. We assessed methane oxidation as represented by the isotopic signal of biomarkers from methane oxidising bacteria (MOB) in multiple surface sediment samples in three distinct areas known to emit varying levels of methane in two shallow Alaskan thermokarst lakes. Diploptene was present and had δ13C values lower than -38gâ° in all sediments analysed, suggesting methane oxidation was widespread. However, there was considerable variation in δ13C values within each area. The most 13C-depleted diploptene was found in an area of high methane ebullition in Ace Lake (diploptene δ13C values between -68.2 and -50.1â°). In contrast, significantly higher diploptene δ13C values (between -42.9 and -38.8gâ°) were found in an area of methane ebullition in Smith Lake. δ13C values of diploptene between -56.8 and -46.9gâ° were found in the centre of Smith Lake, where ebullition rates are low but diffusive methane efflux occurs. The small-scale heterogeneity of the samples may reflect patchy distribution of substrate and/or MOB within the sediments. The two ebullition areas differ in age and type of organic carbon substrate, which may affect methane production, transport, and subsequent oxidation. Given the high amount of variation in surface samples, a more extensive calibration of modern sediment properties, within and among lakes, is required before down-core records of hopanoid isotopic signatures are developed. Š Author(s) 2016
Low-Dimensional Assemblies of Magnetic MnFe2O4 Nanoparticles and Direct In Vitro Measurements of Enhanced Heating Driven by Dipolar Interactions: Implications for Magnetic Hyperthermia
Magnetic fluid hyperthermia (MFH), the procedure of raising the temperature of tumor cells using magnetic nanoparticles (MNPs) as heating agents, has proven successful in treating some types of cancer. However, the low heating power generated under physiological conditions makes it necessary a high local concentration of MNPs at tumor sites. Here, we report how the in vitro heating power of magnetically soft MnFe2O4 nanoparticles can be enhanced by intracellular low-dimensional clusters through a strategy that includes: (a) the design of the MNPs to retain Neel magnetic relaxation in high-viscosity media, and (b) culturing MNP-loaded cells under magnetic fields to produce elongated intracellular agglomerates. Our direct in vitro measurements demonstrated that the specific loss power (SLP) of elongated agglomerates (SLP = 576 +/- 33 W/g) induced by culturing BV2 cells in situ under a dc magnetic field was increased by a factor of 2 compared to the SLP = 305 +/- 25 W/g measured in aggregates freely formed within cells. A numerical mean-field model that included dipolar interactions quantitatively reproduced the SLPs of these clusters both in phantoms and in vitro, suggesting that it captures the relevant mechanisms behind power losses under high-viscosity conditions. These results indicate that in situ assembling of MNPs into low-dimensional structures is a sound possible way to improve the heating performance in MFH
EnzMetâ˘: An Enzymatic Metallography Reagent for Accurately Delineating Neuronal Boundaries for Segmenting Gap Junction-Coupled Neurons in their Three-dimensional Space
Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 - August 2, 201
Microlensing by natural wormholes: theory and simulations
We provide an in depth study of the theoretical peculiarities that arise in
effective negative mass lensing, both for the case of a point mass lens and
source, and for extended source situations. We describe novel observational
signatures arising in the case of a source lensed by a negative mass. We show
that a negative mass lens produces total or partial eclipse of the source in
the umbra region and also show that the usual Shapiro time delay is replaced
with an equivalent time gain. We describe these features both theoretically, as
well as through numerical simulations. We provide negative mass microlensing
simulations for various intensity profiles and discuss the differences between
them. The light curves for microlensing events are presented and contrasted
with those due to lensing produced by normal matter. Presence or absence of
these features in the observed microlensing events can shed light on the
existence of natural wormholes in the Universe.Comment: 16 pages, 24 postscript figures (3 coloured), revtex style, submitted
to Phys. Rev.
Controlling the dominant magnetic relaxation mechanisms for magnetic hyperthermia in bimagnetic core-shell nanoparticles
We report a simple and effective way to control the heat generation of a magnetic colloid under alternate magnetic fields by changing the shell composition of bimagnetic core-shell Fe 3 O 4 /Zn x Co 1-x Fe 2 O 4 nanoparticles. The core-shell structure constitutes a magnetically-coupled biphase system, with an effective anisotropy that can be tuned by the substitution of Co 2+ by Zn 2+ ions in the shell. Magnetic hyperthermia experiments of nanoparticles dispersed in hexane and butter oil showed that the magnetic relaxation is dominated by Brown relaxation mechanism in samples with higher anisotropy (i.e., larger concentration of Co within the shell) yielding high specific power absorption values in low viscosity media as hexane. Increasing the Zn concentration of the shell, diminishes the magnetic anisotropy, which results in a change to a NĂŠel relaxation that dominates the process when the nanoparticles are dispersed in a high-viscosity medium. We demonstrate that tuning the Zn contents at the shell of these exchange-coupled core/shell nanoparticles provides a way to control the magnetic anisotropy without loss of saturation magnetization. This ability is an essential prerequisite for most biomedical applications, where high viscosities and capturing mechanisms are present. This journal i
Monostable controllers for adaptive behavior
Recent artificial neural networks for machine learning have exploited transient dynamics around globally stable attractors, inspired by the properties of cortical microcolumns. Here we explore whether similarly constrained neural network controllers can be exploited for embodied, situated adaptive behaviour. We demonstrate that it is possible to evolve globally stable neurocontrollers containing a single basin of attraction, which nevertheless sustain multiple modes of behaviour. This is achieved by exploiting interaction between environmental input and transient dynamics. We present results that suggest that this globally stable regime may constitute an evolvable and dynamically rich subset of recurrent neural network configurations, especially in larger networks. We discuss the issue of scalability and the possibility that there may be alternative adaptive behaviour tasks that are more âattractor hungryâ
The GEM Project: an International Collaboration to Survey Galactic Radiation Emission
The GEM (Galactic Emission Mapping) project is an international collaboration
established with the aim of surveying the full sky at long wavelengths with a
multi-frequency radio telescope. A total of 745 hours of observation at 408 MHz
were completed from an Equatorial site in Colombia. The observations cover the
celestial band , and . Preliminary results of this partial survey will be
discussed. A review of the instrumental setup and a
resolution sky map at 408 MHz is presented.Comment: 6 pages, Plain Latex + 1 (uuencoded) PostScript figure Fig. 1 and
Fig. 2 not included, available from [email protected]
UHECR Acceleration in Dark Matter Filaments of Cosmological Structure Formation
A mechanism for proton acceleration to ~10^21eV is suggested. It may operate
in accretion flows onto thin dark matter filaments of cosmic structure
formation. The flow compresses the ambient magnetic field to strongly increase
and align it with the filament. Particles begin the acceleration by the ExB
drift with the accretion flow. The energy gain in the drift regime is limited
by the conservation of the adiabatic invariant p_perp^2/B. Upon approaching the
filament, the drift turns into the gyro-motion around the filament so that the
particle moves parallel to the azimuthal electric field. In this 'betatron'
regime the acceleration speeds up to rapidly reach the electrodynamic limit
for an accelerator with magnetic field and the orbit radius
(Larmor radius). The periodic orbit becomes unstable and the particle
slings out of the filament to the region of a weak (uncompressed) magnetic
field, which terminates the acceleration.
The mechanism requires pre-acceleration that is likely to occur in structure
formation shocks upstream or nearby the filament accretion flow. Previous
studies identify such shocks as efficient proton accelerators to a firm upper
limit ~10^19.5 eV placed by the catastrophic photo-pion losses. The present
mechanism combines explosive energy gain in its final (betatron) phase with
prompt particle release from the region of strong magnetic field. It is this
combination that allows protons to overcome both the photo-pion and the
synchrotron-Compton losses and therefore attain energy 10^21 eV. A requirement
on accelerator to reach a given E_max placed by the accelerator energy
dissipation \propto E_{max}^{2}/Z_0 due to the finite vacuum impedance Z_0 is
circumvented by the cyclic operation of the accelerator.Comment: 34 pages, 10 figures, to be published in JCA
Magnetic hyperthermia experiments with magnetic nanoparticles in clarified butter oil and paraffin: A thermodynamic analysis
In specific power absorption models for magnetic fluid hyperthermia (MFH) experiments, the magnetic relaxation time of nanoparticles (NPs) is known to be a fundamental descriptor of the heating mechanisms. The relaxation time is mainly determined by the interplay between the magnetic properties of NPs and the rheological properties of NPsâ environment. Although the role of magnetism in MFH has been extensively studied, the thermal properties of the NP medium and their changes during MFH experiments have been underrated so far. Herein, we show that ZnxFe3-xO4 NPs dispersed through different media with phase transition in the temperature range of experiment as clarified butter oil (CBO) and paraffin. These systems show nonlinear behavior of the heating rate within the temperature range of MFH experiments. For CBO, a fast increase at ~306 K is associated with changes in the viscosity (Âż(T)) and specific heat (cp(T)) of the medium at its melting temperature. This increment in the heating rate takes place around 318 K for paraffin. The magnetic and morphological characterization of NPs together with the observed agglomeration of NPs above 306 and 318 K for CBO and paraffin, respectively, indicate that the fast increase in MFH curves could not be associated with the change in the magnetic relaxation mechanism, with NeĂŠl relaxation being dominant. In fact, successive experimental runs performed up to temperatures below and above the CBO and paraffin melting points resulted in different MFH curves due to agglomeration of NPs driven by magnetic field inhomogeneity during the experiments. Our results highlight the relevance of the thermodynamic properties of the system NP-medium for an accurate measurement of the heating efficiency for in vitro and in vivo environments, where the thermal properties are largely variable within the temperature window of MFH experiments
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