The Implementation of Math Technology Supplemental Programs for Elementary Students

Many studies have focused on using technological devices in elementary education; however, more research is needed on the implementation of technology to improve student learning in math. The problem addressed in this study was the lack of information about how teachers implemented and used the new math software programs, Imagine Math and Reflex in their instruction and their perspectives on differences the programs made in students\u27 math learning. The Technological Pedagogical Content Knowledge (TPACK) served as the conceptual framework for this study. The purpose of the study was to understand how teachers are using the new math software programs and to analyze their perspectives on differences they notice in students\u27 math learning and comfort with online math tools after using the programs. This qualitative case study used data from interviews and observations from local teachers to illuminate the positive and negative aspects of implementing the new software programs. The data were coded into theme categories including usage, strengths, concerns, and professional development. The data showed the participants had generally a positive view of integrating the programs and felt the programs were beneficial to students, that the biggest challenges were lack of training and some technological issues, and TPACK changes were more prevalent for program-experienced teachers and limited to center time for those new to the programs. The finding helped identify the gap between what the math technology programs claim and what the programs actually do for teachers and learners. The potential for social change is to accurately capture the programs\u27 benefits to students and the preparation required by teachers for online learning programs and assessments

Holding On: Older Californians With Disabilities Rely on Public Services to Remain Independent

Presents findings from a study of low-income older Californians with disabilities receiving Medicare, Medi-Cal, and In-Home Supportive Services; their unmet physical, mental health, and social needs; and limited care options. Outlines policy implications

Carolyn Halpin-Healy on her experience as Co-Founder and Executive Director of Arts & Minds in conversation with Sara Torres

Arts&Minds is a non-for-prfit organization and its goal is to improve well-being for people living with dementia and their cargivers through meaningful contact with art. They partner with the Studio Museum in Harlem, the New York Historical Sociaty, El Museo del Barrio and the Metropolitan Museum of Art

Physical Activity Effects on Depressive Symptoms in Black Adults

Objectives: Randomized trials found physical activity (PA) effective in decreasing depressive symptoms. Few studies included Black participants. The purpose of this systematic literature review was to determine the effects of PA on depressive symptoms in Black adults. Methods: Articles were abstracted by conducting a computer and hand search of eligible studies. Results: Eight of 13 studies found a significant inverse relationship between PA and depressive symptoms in Black adults. Sources for the heterogeneity were explored. Conclusion: Future studies should include representative samples of Black adults, incorporate a theory which considers multiple levels of influence, account for genetic factors in the etiology of depressive symptoms, include individuals diagnosed with depression and with health conditions which may increase the risk of depressive symptoms, account for intra-group ethnic heterogeneity, measure and differentiate between social support and social network, consider aspects of the physical environment and use standardized measurements of PA

Depressive Symptoms and Walking in African‐Americans

Objective Although increased frequency of physical activity is associated with fewer depressive symptoms in African‐Americans, most studies do not focus on a specific type of activity. Identifying the activity can provide helpful information for designing interventions that focus on depressive symptoms. The objective of this study was to examine the odds of depressive symptoms in relation to walking in African‐Americans. Design and Sample A secondary analysis was performed on the National Survey of American Life. The sample was made up of community‐dwelling African‐American women (n = 1,903) and men (n = 1,075) who did not meet the DSM‐IV‐TR criteria for depression. Measures Walking was measured by self‐reported frequency (i.e., never, rarely, sometimes, often). Depressive symptoms were measured with the Center for Epidemiologic Studies Depression scale. Logistic regression for complex samples was used to examine the odds of depressive symptoms in relation to walking. Results Women who reported often walking had lower odds for depressive symptoms than women who reported never walking (OR = 0.56, 95% CI = 0.38–0.82). Walking frequency was not related to depressive symptoms in men. Conclusions Walking frequency is a modifiable risk factor for elevated depressive symptoms in African‐American women

Leisure-time Physical Activity in Relation to Depressive Symptoms in African-Americans: Results from the National Survey of American Life

Objective To examine the frequency of leisure-time physical activity (LTPA) in relation to depressive symptoms in a nationally representative sample of African American (AA) women and AA men with guidance by Stokols\u27 Social Ecological Framework. Method A secondary analysis of AA women (n = 1811) and AA men (n = 1038) was performed on the National Survey of American Life, where a four stage national area probability sampling was conducted. Interviews were conducted 2001–2003. Clinically depressed AA were excluded from the current study. LTPA was measured by self-report frequency (never, rarely, sometimes, often) of participation in sports/exercise. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression scale. Logistic regression for complex samples was used to examine the relationship between LTPA and depressive symptoms, adjusting for biopsychobehavioral and sociophysical environmental factors. Results Compared with AA women and AA men who reported never participating in LTPA, the multivariate OR for depressive symptoms in AA women and AA men who reported participating in LTPA often was 0.42 (95% CI = 0.24–0.72) and 0.41 (95% CI = 0.25–0.69) respectively. Conclusion Increased frequency of LTPA was associated with fewer depressive symptoms in a nationally representative sample of non-clinically depressed AAs

Gardening/Yard Work and Depressive Symptoms in African Americans

Background The purpose of this study was to examine the frequency of gardening/yard work in relation to depressive symptoms in African-Americans while controlling for biological and social factors. Methods A secondary analysis was performed on the National Survey of American Life (n = 2,903) using logistic regression for complex samples. Gardening/Yard work was measured by self-reported frequency. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression scale. Results Biological and social factors, not gardening/yard work, were associated with depressive symptoms. Conclusions Biological and social factors may need to be addressed before the association between gardening/yard work and depressive symptoms can be determined

Identification of an Archaeal Presenilin-Like Intramembrane Protease

BACKGROUND: The GXGD-type diaspartyl intramembrane protease, presenilin, constitutes the catalytic core of the γ-secretase multi-protein complex responsible for activating critical signaling cascades during development and for the production of β-amyloid peptides (Aβ) implicated in Alzheimer's disease. The only other known GXGD-type diaspartyl intramembrane proteases are the eukaryotic signal peptide peptidases (SPPs). The presence of presenilin-like enzymes outside eukaryots has not been demonstrated. Here we report the existence of presenilin-like GXGD-type diaspartyl intramembrane proteases in archaea. METHODOLOGY AND PRINCIPAL FINDINGS: We have employed in vitro activity assays to show that MCMJR1, a polytopic membrane protein from the archaeon Methanoculleus marisnigri JR1, is an intramembrane protease bearing the signature YD and GXGD catalytic motifs of presenilin-like enzymes. Mass spectrometry analysis showed MCMJR1 could cleave model intramembrane protease substrates at several sites within their transmembrane region. Remarkably, MCMJR1 could also cleave substrates derived from the β-amyloid precursor protein (APP) without the need of protein co-factors, as required by presenilin. Two distinct cleavage sites within the transmembrane domain of APP could be identified, one of which coincided with Aβ40, the predominant site processed by γ-secretase. Finally, an established presenilin and SPP transition-state analog inhibitor could inhibit MCMJR1. CONCLUSIONS AND SIGNIFICANCE: Our findings suggest that a primitive GXGD-type diaspartyl intramembrane protease from archaea can recapitulate key biochemical properties of eukaryotic presenilins and SPPs. MCMJR1 promises to be a more tractable, simpler system for in depth structural and mechanistic studies of GXGD-type diaspartyl intramembrane proteases

COVID-19 Vaccination Uptake, Infection Rates, and Seropositivity Among Youth Experiencing Homelessness in the United States.

People experiencing homelessness are at greater risk of exposure and poor health outcomes from COVID-19. Yet, little data exists on the prevalence and correlates of COVID-19 among homeless populations. To mitigate the spread and severity, uptake of the COVID-19 vaccine is needed. This can be challenging among youth experiencing homelessness who are more likely to be unvaccinated when compared to stably housed youth