191 research outputs found
Analytic provenance as constructs of behavioural markers for externalizing thinking processes in criminal intelligence analysis
Studying how analysts use interaction in visualization systems is an important part of evaluating how well these interactions support analysis needs, like generating insights or performing tasks. Analytic Provenance commonly known as interaction histories contains information about the sequence of choices that analysts make when exploring data or performing a task. This research work presents a compositional reductionist approach as a way of externalizing analyst’s thinking processes by using markers of analytical behaviour extracted from such interaction histories. Set of Behavioural Markers (BMs) have been identified through a workshop with domain experts and a systematic literature review to use them as cognitive attributes of imagination, insight, transparency, fluidity and rigour to enhance performance in criminal intelligence analysis. A low level semantic action sequence computation also has been proposed as a detection approach of identified BMs and found from computation that BMs can act as bridge between human cognition and computation through semantic interaction. This research work has addressed problems of existing qualitative experiments to extract these BMs through cognitive task analysis and found that the proposed computational technique can be a supplementary approach for validating experimental results
Modelling creativity: identifying key components through a corpus-based approach
Creativity is a complex, multi-faceted concept encompassing a variety of related aspects, abilities, properties and behaviours. If we wish to study creativity scientifically, then a tractable and well-articulated model of creativity is required. Such a model would be of great value to researchers investigating the nature of creativity and in particular, those concerned with the evaluation of creative practice. This paper describes a unique approach to developing a suitable model of how creative behaviour emerges that is based on the words people use to describe the concept. Using techniques from the field of statistical natural language processing, we identify a collection of fourteen key components of creativity through an analysis of a corpus of academic papers on the topic. Words are identified which appear significantly often in connection with discussions of the concept. Using a measure of lexical similarity to help cluster these words, a number of distinct themes emerge, which collectively contribute to a comprehensive and multi-perspective model of creativity. The components provide an ontology of creativity: a set of building blocks which can be used to model creative practice in a variety of domains. The components have been employed in two case studies to evaluate the creativity of computational systems and have proven useful in articulating achievements of this work and directions for further research
A Standardised Procedure for Evaluating Creative Systems: Computational Creativity Evaluation Based on What it is to be Creative
Computational creativity is a flourishing research area, with a variety of creative systems being produced and developed. Creativity evaluation has not kept pace with system development with an evident lack of systematic evaluation of the creativity of these systems in the literature. This is partially due to difficulties in defining what it means for a computer to be creative; indeed, there is no consensus on this for human creativity, let alone its computational equivalent. This paper proposes a Standardised Procedure for Evaluating Creative Systems (SPECS). SPECS is a three-step process: stating what it means for a particular computational system to be creative, deriving and performing tests based on these statements. To assist this process, the paper offers a collection of key components of creativity, identified empirically from discussions of human and computational creativity. Using this approach, the SPECS methodology is demonstrated through a comparative case study evaluating computational creativity systems that improvise music
Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model
<p>Abstract</p> <p>Background</p> <p>Skin manifestations of Tuberous Sclerosis Complex (TSC) cause significant morbidity. The molecular mechanism underlying TSC is understood and there is evidence that systemic treatment with rapamycin or other mTOR inhibitors may be a useful approach to targeted therapy for the kidney and brain manifestations. Here we investigate topical rapamycin in a mouse model for TSC-related tumors.</p> <p>Methods</p> <p>0.4% and 0.8% rapamycin ointments were applied to nude mice bearing subcutaneous, TSC-related tumors. Topical treatments were compared with injected rapamycin and topical vehicle. Rapamycin levels in blood and tumors were measured to assess systemic drug levels in all cohorts.</p> <p>Results</p> <p>Treatment with topical rapamycin improved survival and reduced tumor growth. Topical rapamycin treatment resulted in systemic drug levels within the known therapeutic range and was not as effective as injected rapamycin.</p> <p>Conclusion</p> <p>Topical rapamycin inhibits TSC-related tumor growth. These findings could lead to a novel treatment approach for facial angiofibromas and other TSC skin lesions.</p
Individual differences in the use of the response scale determine valuations of hypothetical health states: an empirical study
Background. The effects of socio-demographic characteristics of the respondent, including age, on valuation scores of hypothetical health states remain inconclusive. Therefore, we analyzed data from a study designed to discriminate between the effects of respondents' age and time preference on valuations of health states to gain insight in the contribution of individual response patterns to the variance in valuation scores. Methods. A total of 212 respondents from three age g
Creativity as development : discourse, ideology and practice
What the new global policy imaginary of "creativity" has amounted to is, on the one hand, a profoundly disintegrated research landscape with a heavy interest in creative “industries” (Cho, Liu, & Ho, 2018) and, on the other hand, an approach to development framed by a somewhat more general and hegemonic global ideology on culture, the arts, and development (Garner, 2016; Stupples, 2014). This “ideology” is mediated by global or UN-level policy and indeed specific to an age in which the neoliberal global economy has established an unprecedented degree of certitude and political consensus across the world on how we develop a prosperous society. Creativity has become a powerful signifier around which a rhetoric of dynamic trade, growth, and opportunity has evolved, and is subject to a broad assessment in this chapter
Programa de intervención en representaciones de creatividad y motivación académica de adolescentes
Creativity and its promotion are widespread concerns in education. However, few efforts have been made to implement
intervention programs designed to promote creativity and other related aspects (e.g., academic motivation). The Future Problem Solving
Program International (FPSPI), aimed for training creativity representations and creative problem solving skills in young people, has
been one of the most implemented programs. This intervention’s materials and activities were adapted for Portuguese students, and
a longitudinal study was conducted. The program was implemented during four months, in weekly sessions, by thirteen teachers.
Teachers received previous training for the program and during the program’s implementation. Intervention participants included
77 Basic and Secondary Education students, and control participants included 78 equivalent students. Pretest-posttest measures of
academic motivation and creativity representations were collected. Results suggest a significant increase, in the intervention group,
in motivation and the appropriate representations of creativity. Practical implications and future research perspectives are presented.A criatividade e sua promoção geram grande preocupação em educação. Contudo, poucos esforços têm existido para
implementar programas destinados a sua promoção e de outros aspetos relacionados (e.g., motivação acadêmica). O Future Problem
Solving Program International (FPSPI), criado para melhorar as representações de criatividade e a resolução criativa de problemas
em jovens, tem sido um dos mais implementados. Os seus materiais e atividades foram adaptados para estudantes portugueses,
efetuando-se um estudo longitudinal. O programa foi implementado durante quatro meses, semanalmente, por treze professores, que
receberam formação antes e durante a implementação. O grupo experimental incluiu 77 estudantes do Ensino Básico e Secundário,
apresentando o grupo de controlo 78 estudantes com características equivalentes. Os dados sobre a motivação e criatividade foram
recolhidos num pré e pós-teste. Os resultados sugerem um aumento significativo na motivação e crenças apropriadas de criatividade
no grupo experimental. Implicações práticas e perspectivas para investigações futuras são apresentadas.La creatividad y su promoción generan gran preocupación en educación. Sin embargo, han sido llevados a cabo pocos
esfuerzos para implementar programas de promoción de la creatividad y otros aspectos (e.g., motivación académica). El Future
Problem Solving Program International (FPSPI), creado para mejorar las representaciones de creatividad y la solución creativa de
problemas en jóvenes, ha sido bastante implementado. Se adaptaron sus materiales y actividades para estudiantes portugueses, y
se desarrolló un estudio longitudinal. El programa se implementó semanalmente durante cuatro meses por trece profesores, que
recibieron formación antes y durante la implementación. El grupo experimental incluyó 77 estudiantes de Educación Primaria y
Secundaria y el grupo de control incluyó 78 estudiantes con características semejantes. Los datos de motivación y creatividad fueron
recogidos en un pre y post-test, sugiriendo un aumento significativo de motivación y creencias apropiadas sobre la creatividad en el
grupo experimental. Se presentan implicaciones prácticas y perspectivas para futuras investigaciones.Fundação para a Ciência e a Tecnologia (FCT) - SFRH/BPD/80825/201
Psychologie der Kreativität
Ein kleiner Streifzug durch die psychologische Kreativitätsforschung befasst sich mit den Möglichkeiten der Erfassung kreativer Prozesse, ihrer Manifestation, den Determinanten, der Frage nach der Notwendigkeit zu kreativem Denken und schließlich Erkenntnissen darüber, wie kreatives Denken gefördert werden kann
Cerebral Blood Flow during Rest Associates with General Intelligence and Creativity
Recently, much scientific attention has been focused on resting brain activity and its investigation through such methods as the analysis of functional connectivity during rest (the temporal correlation of brain activities in different regions). However, investigation of the magnitude of brain activity during rest has focused on the relative decrease of brain activity during a task, rather than on the absolute resting brain activity. It is thus necessary to investigate the association between cognitive factors and measures of absolute resting brain activity, such as cerebral blood flow (CBF), during rest (rest-CBF). In this study, we examined this association using multiple regression analyses. Rest-CBF was the dependent variable and the independent variables included two essential components of cognitive functions, psychometric general intelligence and creativity. CBF was measured using arterial spin labeling and there were three analyses for rest-CBF; namely mean gray matter rest-CBF, mean white matter rest-CBF, and regional rest-CBF. The results showed that mean gray and white matter rest-CBF were significantly and positively correlated with individual psychometric intelligence. Furthermore, mean white matter rest-CBF was significantly and positively correlated with creativity. After correcting the effect of mean gray matter rest-CBF the significant and positive correlation between regional rest-CBF in the perisylvian anatomical cluster that includes the left superior temporal gyrus and insula and individual psychometric intelligence was found. Also, regional rest-CBF in the precuneus was significantly and negatively correlated with individual creativity. Significance of these results of regional rest-CBF did not change when the effect of regional gray matter density was corrected. The findings showed mean and regional rest-CBF in healthy young subjects to be correlated with cognitive functions. The findings also suggest that, even in young cognitively intact subjects, resting brain activity (possibly underlain by default cognitive activity or metabolic demand from developed brain structures) is associated with cognitive functions
The Rough Guide to In Silico Function Prediction, or How To Use Sequence and Structure Information To Predict Protein Function
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