551 research outputs found
Susceptibility of Selected Ericaceous Ornamental Host Species to Phytophthora ramorum
We assessed disease reactions of 51 species or varieties of ericaceous ornamental hosts to two isolates of Phytophthora ramorum, the causal agent of sudden oak death. Inoculation was performed with an A2 mating type U.S. isolate from rhododendron and the P. ramorum type culture of A1 mating type from Germany. For only one host were statistically significant differences in disease observed between the two isolates. Several different inoculation methods were compared. The 51 hosts tested varied widely in susceptibility, ranging from 0% to over 90% leaf area infected. Two cultivars of Vaccinium macrocarpon (cranberry) showed no disease, while three cultivars of Kalmia latifolia (mountain laurel) were all highly susceptible. The results indicate that many ornamental hosts grown in the United States are susceptible to P. ramorum under artificial inoculation conditions. Inoculum density studies with two susceptible host species showed that P. ramorum is capable of producing disease symptoms over sporangium concentrations ranging from 100 to 5,000 sporangia per ml. Mean numbers of chlamydospores forming in host tissue of 21 hosts ranged from 2 to over 900 chlamydospores per 6-mm-diameter leaf disk. Whether hosts showing susceptiblity under the experimental conditions used in this study would become infected with P. ramorum in the presence of inoculum under natural conditions is unknown
The Relationship Antecedents of Smoking (RAS) Scale: A new scale to assess couple-focused triggers to smoke.
The purpose of this pilot study is to assess the reliability and construct validity of a measure of relationship-focused antecedents for smoking (RAS). The scale includes both positively-valenced items (e.g.. âI feel like smoking when I am relaxing with my partnerâ) and negatively-valenced items (e.g., âI feel like smoking when my partner criticizes meâ). Participants included 123 individuals who smoke cigarettes with co-habitating smoking (n=63) or non-smoking (n=60) romantic partners. Participants completed the RAS and a series of measures associated with smoking outcomes. Principal component analysis with varimax rotation resulted in a 2-component solution. The RAS showed excellent internal consistency for the total scale (α=.96) and for the positive (α=.88) and negative (α=.97) subscales. Higher positive subscale scores were associated with lower motivation to quit while higher negative scores were associated with lower relationship satisfaction and dyadic efficacy to quit. Higher scores on both subscales were related to higher social motives, dependence motives, and social outcome expectances. Participants with smoking partners reported higher positive subscale scores and lower negative subscale scores. The RAS may be helpful in the design of smoking cessation interventions for couples
Individual Differences in Eye-Movements During Reading: Working Memory and Speed-of-Processing Effects
Mathematical models of eye-movement control do not yet incorporate individual differences as a source of variation in reading. These models nonetheless provide an excellent foundation for describing and explaining how and why patterns of eye-movements differ across readers (e.g., Rayner et al., 2006). We focus in this article on two aspects of individual variation: global processing speed (e.g., Salthouse, 1996) and working-memory capacity (e.g., Just & Carpenter, 1992). Using Hierarchical Linear Modeling (HLM) (Raudenbush & Bryk, 2001), we tested the extent to which overall reading speed and working-memory capacity moderate the degree to which syntactic and semantic information affect fixation times. We found that working-memory capacity interacted with sentence-characteristic variables only when processing speed was not included in the model
Interleukin-3 greatly expands non-adherent endothelial forming cells with pro-angiogenic properties
Circulating endothelial progenitor cells (EPCs) provide revascularisation for cardiovascular disease and the expansion of these cells opens up the possibility of their use as a cell therapy. Herein we show that interleukin-3 (IL3) strongly expands a population of human non-adherent endothelial forming cells (EXnaEFCs) with low immunogenicity as well as pro-angiogenic capabilities in vivo, making their therapeutic utilisation a realistic option. Non-adherent CD133âș EFCs isolated from human umbilical cord blood and cultured under different conditions were maximally expanded by day 12 in the presence of IL3 at which time a 350-fold increase in cell number was obtained. Cell surfacemarker phenotyping confirmed expression of the hematopoietic progenitor cellmarkers CD133, CD117 and CD34, vascular cell markers VEGFR2 and CD31, dim expression of CD45 and absence of myeloid markers CD14 and CD11b. Functional experiments revealed that EXnaEFCs exhibited classical properties of endothelial cells (ECs), namely binding of Ulex europaeus lectin, up-take of acetylated-low density lipoprotein and contribution to EC tube formation in vitro. These EXnaEFCs demonstrated a pro-angiogenic phenotype within two independent in vivo rodent models. Firstly, a Matrigel plug assay showed increased vascularisation in mice. Secondly, a rat model of acute myocardial infarction demonstrated reduced heart damage as determined by lower levels of serum creatinine and a modest increase in heart functionality. Taken together, these studies show IL3 as a potent growth factor for human CD133âș cell expansion with clear pro-angiogenic properties (in vitro and in vivo) and thusmay provide clinical utility for humans in the future.Lachlan M. Moldenhauer, Michaelia P. Cockshell, Lachlan Frost, Kate A. Parham, Denis Tvorogov, Lih Y. Tan, Lisa M. Ebert, Katie Tooley, Stephen Worthley, Angel F. Lopez, Claudine S. Bonde
School performance in Australia: is there a role for quasi-markets?
Recent changes to the organisation of Australia's education system have raised the possibility of implementing wide-ranging market reforms. In this article we discuss the scope for introducing reforms similar to the United Kingdom's 'quasi-market' model. We discuss the role of school league tables in providing signals and incentives in a quasi-market. Specifically, we compare a range of unadjusted and model-based league tables of primary school performance in Queensland's public education system. These comparisons indicate that model-based tables which account for socio-economic status and student intake quality vary significantly from the unadjusted tables
Early stressful experiences are associated with reduced neural responses to naturalistic emotional and social content in children
How do childrenâs experiences relate to their naturalistic emotional and social processing? Because children can struggle with tasks in the scanner, we collected fMRI data while 4-to-11-year-olds watched a short film with positive and negative emotional events, and rich parent-child interactions (n = 70). We captured broad, normative stressful experiences by examining socioeconomic status (SES) and stressful life events, as well as childrenâs more proximal experiences with their parents. For a sub-sample (n = 30), parenting behaviors were measured during a parent-child interaction, consisting of a picture book, a challenging puzzle, and free play with novel toys. We characterized positive parenting behaviors (e.g., warmth, praise) and negative parenting behaviors (e.g., harsh tone, physical control). We found that higher SES was related to greater activity in medial orbitofrontal cortex during parent-child interaction movie events. Negative parenting behaviors were associated with less activation of the ventral tegmental area and cerebellum during positive emotional events. In a region-of-interest analysis, we found that stressful life events and negative parenting behaviors were associated with less activation of the amygdala during positive emotional events. These exploratory results demonstrate the promise of using movie fMRI to study how early experiences may shape emotional, social, and motivational processes
What makes you not a Buddhist? : a preliminary mapping of values
This study sets out to establish which Buddhist values contrasted with or were shared by adolescents from a non-Buddhist population. A survey of attitude toward a variety of Buddhist values was fielded in a sample of 352 non-Buddhist schoolchildren aged between 13 and 15 in London. Buddhist values where attitudes were least positive concerned the worth of being a monk/nun or meditating, offering candles & incense on the Buddhist shrine, friendship on Sangha Day, avoiding drinking alcohol, seeing the world as empty or impermanent and Nirvana as the ultimate peace. Buddhist values most closely shared by non-Buddhists concerned the Law of Karma, calming the mind, respecting those deserving of respect, subjectivity of happiness, welfare work, looking after parents in old age and compassion to cuddly animals. Further significant differences of attitude toward Buddhism were found in partial correlations with the independent variables of sex, age and religious affiliation. Correlation patterns paralleled those previously described in theistic religions. Findings are applied to spiritual, moral, social and cultural development and for the teaching of religious to pupils of no faith adherence. The study recommends that quantitative psychometrics employed to conceptualize Buddhist values by discriminant validity in this study could be extended usefully to other aspects of the study of Buddhism, particularly in quest of validity in the conceptualization of Buddhist identity within specifically Buddhist populations
Policy Feedback and the Politics of the Affordable Care Act
There is a large body of literature devoted to how âpolicies create politicsâ and how feedback effects from existing policy legacies shape potential reforms in a particular area. Although much of this literature focuses on selfâreinforcing feedback effects that increase support for existing policies over time, Kent Weaver and his colleagues have recently drawn our attention to selfâundermining effects that can gradually weaken support for such policies. The following contribution explores both selfâreinforcing and selfâundermining policy feedback in relationship to the Affordable Care Act, the most important healthâcare reform enacted in the United States since the midâ1960s. More specifically, the paper draws on the concept of policy feedback to reflect on the political fate of the ACA since its adoption in 2010. We argue that, due in part to its sheer complexity and fragmentation, the ACA generates both selfâreinforcing and selfâundermining feedback effects that, depending of the aspect of the legislation at hand, can either facilitate or impede conservative retrenchment and restructuring. Simultaneously, through a discussion of partisan effects that shape Republican behavior in Congress, we acknowledge the limits of policy feedback in the explanation of policy stability and change
Critical Race Theory and Education: racism and anti-racism in educational theory and praxis
What is Critical Race Theory (CRT) and what does it offer educational researchers and practitioners outside the US? This paper addresses these questions by examining the recent history of antiracist research and policy in the UK. In particular, the paper argues that conventional forms of antiracism have proven unable to keep pace with the development of increasingly racist and exclusionary education polices that operate beneath a veneer of professed tolerance and diversity. In particular, contemporary antiracism lacks clear statements of principle and theory that risk reinventing the wheel with each new study; it is increasingly reduced to a meaningless slogan; and it risks appropriation within a reformist âcan doâ perspective dominated by the de-politicized and managerialist language of school effectiveness and improvement. In contrast, CRT offers a genuinely radical and coherent set of approaches that could revitalize critical research in education across a range of inquiries, not only in self-consciously "multicultural" studies. The paper reviews the developing terrain of CRT in education, identifying its key defining elements and the conceptual tools that characterise the work. CRT in education is a fast changing and incomplete project but it can no longer be ignored by the academy beyond North America
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