25 research outputs found
Spectral footprints of impurity scattering in graphene nanoribbons
We report a detailed investigation of the interplay between size quantization
and local scattering centers in graphene nanoribbons, as seen in the local
density of states. The spectral signatures, obtained after Fourier
transformation of the local density of states, include characteristic peaks
that can be related to the transverse modes of the nanoribbon. In armchair
ribbons, the Fourier transformed density of states of one of the two
inequivalent sublattices takes a form similar to that of a quantum channel in a
two-dimensional electron gas, modified according to the differences in
bandstructure. After addition of the second sublattice contribution, a
characteristic modulation of the pattern due to superposition is obtained,
similar to what has been obtained in spectra due to single impurity scattering
in large-area graphene. We present analytic results for the electron propagator
in armchair nanoribbons in the Dirac approximation, including a single
scattering center within a T-matrix formulation. For comparison, we have
extended the investigation with numerics obtained with an atomistic recursive
Green's function approach. The spectral signatures of the atomistic approach
include the effects of trigonal warping. The impurity induced oscillations in
the local density of states are not decaying at large distance in few-mode
nanoribbons.Comment: 21 pages, 12 figure
Destroyed quantum Hall effect in graphene with [0001] tilt grain boundaries
The reason why the half-integer quantum Hall effect (QHE) is suppressed in
graphene grown by chemical vapor deposition (CVD) is unclear. We propose that
it might be connected to extended defects in the material and present results
for the quantum Hall effect in graphene with [0001] tilt grain boundaries
connecting opposite sides of Hall bar devices. Such grain boundaries contain
5-7 ring complexes that host defect states that hybridize to form bands with
varying degree of metallicity depending on grain boundary defect density. In a
magnetic field, edge states on opposite sides of the Hall bar can be connected
by the defect states along the grain boundary. This destroys Hall resistance
quantization and leads to non-zero longitudinal resistance. Anderson disorder
can partly recover quantization, where current instead flows along returning
paths along the grain boundary depending on defect density in the grain
boundary and on disorder strength. Since grain sizes in graphene made by
chemical vapor deposition are usually small, this may help explain why the
quantum Hall effect is usually poorly developed in devices made of this
material.Comment: 5 pages, 4 figure
KIMOD 1.0 Documentation of NIER´s Dynamic Macroeconomic General Equilibrium Model of the Swedish Economy
KIMOD 1.0 is an annual large-scale macroeconomic model2 of the Swedish economy and is the result of a project that started in 2002 at the National Institute of Economic Research (NIER) in Sweden. In 2003, the model was used for the first time in policy analysis (see NIER, 2003) and from 2004 onwards it has also been applied for forecasting purposes. In November 2005, the time had come to document the first official version of the model, KIMOD 1.0. This document is a resulting part of the documentation project.
Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome
Objective Quantitative Structure-Activity Relationship (QSAR) models can predict adverse drug reactions (ADRs), and thus provide early warnings of potential hazards. Timely identification of potential safety concerns could protect patients and aid early diagnosis of ADRs among the exposed. Our objective was to determine whether global spontaneous reporting patterns might allow chemical substructures associated with Stevens-Johnson Syndrome (SJS) to be identified and utilized for ADR prediction by QSAR models
An Interoperability Platform Enabling Reuse of Electronic Health Records for Signal Verification Studies
Depending mostly on voluntarily sent spontaneous reports, pharmacovigilance studies are hampered by low quantity and quality of patient data. Our objective is to improve postmarket safety studies by enabling safety analysts to seamlessly access a wide range of EHR sources for collecting deidentified medical data sets of selected patient populations and tracing the reported incidents back to original EHRs. We have developed an ontological framework where EHR sources and target clinical research systems can continue using their own local data models, interfaces, and terminology systems, while structural interoperability and Semantic Interoperability are handled through rule-based reasoning on formal representations of different models and terminology systems maintained in the SALUS Semantic Resource Set. SALUS Common Information Model at the core of this set acts as the common mediator. We demonstrate the capabilities of our framework through one of the SALUS safety analysis tools, namely, the Case Series Characterization Tool, which have been deployed on top of regional EHR Data Warehouse of the Lombardy Region containing about 1 billion records from 16 million patients and validated by several pharmacovigilance researchers with real-life cases. The results confirm significant improvements in signal detection and evaluation compared to traditional methods with the missing background information
The Subject Language Use In Year 8 TIMSS-Test Questions : A Comparison Of Language Uses In Science And Mathematics
In this study we want to make a contribution by making a comparison between the subject languages in mathematics and science based on linguistic theories about language and language function. Through this theoretical foundation in this present study we also have the opportunity to analyze the language function and thus we can also discuss the language's role in teaching. The aim of this study is to compare and thus gain more knowledge of grammatical features in subject language in science and mathematics and how these grammatical features are used to express meaning. To fulfil this purpose, science and mathematics items from Trends in International Mathematics and Science Study (TIMSS) 2011, grade eight, have been analysed from a functional perspective on language. Empirical studies that compare language use in different subjects are sparsely present (Österholm & Bergqvist, 2013) but there are studies pointing out that how language are used to express meaning varies between different school subjects (e.g. Fang & Schleppegrell, 2008; Schleppegrell, 2004). These linguistic differences have been highlighted as arguments for a more differentiated language-based teaching of subjects, leaning on disciplinary literacy (Shanahan & Shanahan, 2008). In order to conduct such a language-based teaching of subjects, an awareness of the different functions in the language used in various school subject is of great importance. One example of a comparative language study is the corpus study conducted by Ribeck (2015) where the language in Swedish teaching materials in science is analyzed, and compared with teaching materials in social science and with textbooks in mathematics. However, Ribeck does not make a direct analysis of mathematical subject language, her focus is rather on the language used in natural science compared to social science. There are also studies that focuses on the language use within subjects. Here it appears that the subject language is used differently and has different functions in different content areas within school mathematics (e.g. Bergvall, 2016) as well as within the different school science subjects, e.g. biology, physics, chemistry and earth science (e.g. Persson, 2016).  This study draws on a social semiotic perspective and systemic functional linguistics (SFL) (Halliday & Matthiessen, 2004). A point of departure is the perspective that different registers of language are used in different social contexts, which in this study is defined as the two school subjects science and mathematics. Grounded in SFL and the three meta-functions ideational, interpersonal and textual function the meaning dimension model of analysis was developed in a previous research project (Bergvall et al., 2016; Persson et al., 2016). Four central meaning dimensions, packing, precision, personification and presentation, were condensed from previous research regarding academic language and language use in the school subjects science and mathematics. The meaning dimensions can be used as measures of how grammatical features are used in various types of texts in order to express meaning. Packing and precision are regarded as aspects of the ideational meta-function. Packing is a measure of the information density in a text and precision is a measure of how and to what extent the given information in the text is specified. Personification, as an aspect of the interpersonal meta-function, is a measure of how personal relations between the reader and the text are expressed. The last meaning dimension, presentation, concerns how the information is structured in the text and is regarded as an aspect of the textual meta-function. In the present study, the four meaning dimensions are used to describe and compare the language and its function in science and mathematics items in TIMSS 2011. Method By the use of a quantitative method all items in mathematics and science from the Swedish version of TIMSS 2011, grade eight were analyzed. This material consists of 197 items in science and 217 items in mathematics. The language in these items have been analyzed for word class, word length and number of words per items by a computer based automatic parsing. For this parsing Extensible Markup Language (XML) was used. Some other linguistic features, i.e. passive forms and subordinate clauses, were identified manually. Since the meaning dimensions are used as a base for the linguistic analysis, the results will possibly be generally applicable also for other European languages, although the analysis was conducted on the Swedish version of TIMSS items. Packing was measured by calculating the number of nouns and the number of long words (>6 characters). Precision in the items were provided by words such as adjectives, adverbs, participles and counting words specifying different attributes in the items. Personification was here measured by the number of personal pronouns and proper names and presentation was measured by the presence of subordinate clauses and passive forms. In order to compensate for the varying length of different items, the number of the different linguistic features were divided by the number of words in the particular item. To enable the adding of different features, each feature is normalized by calculating its z-score. An index was then calculated for each meaning dimension based on the linguistic information on each item. From these indices a comparison between the language uses in the two subjects was possible. In the next step of the analysis each subject were separated into content domains: Algebra, Data & chance, Geometry and Numbers for mathematics items and Biology, Chemistry, Earth science and Physics for science items. This enabled variations of language use within the subjects also to be analyzed. The results were compiled in box-plots diagrams which visualized the distribution of the expressions of the four meaning dimensions in the various content domains. Expected Outcomes Preliminary results show that central traits of the academic language as measured by the four meaning dimensions are used in similar ways in both science and mathematics. The levels of packing, precision and presentation are fairly similar when looking at differences between the subjects. Personification shows the largest differences between the subjects, where mathematics as a whole makes more use of personal pronouns and proper names in the items. When separating the subjects into content domains, Statistics shows the highest level of personification. In this domain it can therefore be concluded that human participants are essential, thus emphasizing that this is a domain that this is an area of relevance for people in general or for the student him/herself. This can be interpreted as signaling the possibility to actively participate and interact in similar situations as described by the items context. On the other hand, in domains such as Algebra, Geometry and Earth science where the content is expressed with a low level of personification, the interpretation is that the content of these domains –at least as expressed in TIMSS items- are more separated from peoples’ everyday lives and thus the students’ own reality. Another result that emerges from the analysis relates to the meaning dimension presentation where we see that the written texts, especially in Algebra, but also in Geometry, Numbers and Earth science, mainly contains short sentences without subordinate clauses. In written academic language, subordinate clauses are a common tool for creating information flow and link different parts of the text (Fang, 2006; Schleppegrell, 2004; Veel, 1997). The lack of subordinate clauses in tasks in certain content areas of TIMSS indicates a subject-specific linguistic form that may require a familiarity with this specific form of language use. References Bergvall, I. (2016). Bokstavligt, bildligt och symboliskt i skolans matematik – en studie om ämnesspråk i TIMSS. [Diss.] Uppsala: Acta Universitatis Upsaliensis. Bergvall, I., Wiksten Folkeryd, J., & Liberg, C. (2016). Linguistic features and their function in different mathematical content areas in TIMSS 2011. Nordic Studies in Mathematics Education, 21(2), 45-68. Fang, Z. (2006). The Language Demands of Science Reading in Middle School, International Journal of Science Education, 28(5) 491-520. Fang, Z., & Schleppegrell, M. J. (2008). Reading in secondary content areas: A language-based pedagogy. Ann Arbor: University of Michigan Press. Halliday, M. A. K., & Matthiessen, C. M. I. M. (2004). An introduction to functional grammar (3.th ed.). London: Arnold. Persson, Tomas (2016). De naturvetenskapliga ämnesspråken. De naturvetenskapliga uppgifterna i och elevers resultat från TIMSS 2011 år 8. [Diss.] Uppsala: Acta Universitatis Upsaliensis. Persson, T., af Geijerstam, Å., & Liberg, C. (2016). Features and functions of scientific language(s) in TIMSS 2011. Nordic Studies in Science Education, 12(2), 176-196. Ribeck, Judy (2015). Steg för steg. Naturvetenskapligt ämnesspråk som räknas. [Diss.] Data linguistica. No. 28, Institutionen för svenska språket, Göteborgs universitet. Shanahan, T., & Shanahan, C. (2008). Teaching disciplinary literacy to adolescents: Rethinking content-area literacy. Harvard Educational Review, 78(1), 40–59. Schleppegrell, M. J. (2004). The language of schooling; a functional linguistics perspective. London: Lawrence Erlbaum Associates. Veel, R. (1997). Learning How to Mean-Scientifically Speaking: Apprenticeship into Scientific Discourse in the Secondary School. In. Christie Frances & Jim R. Martin (Eds.), Genre and Institutions: Social Processes in the Workplace and School, s. 161-195. London: Cassell. Österholm, M. & Bergqvist, E. (2013). What is so special about mathematical texts? Analyses of common claims in research literature and of properties of textbooks. ZDM Mathematics education, 45(5) 751-763
The Subject Language Use In Year 8 TIMSS-Test Questions : A Comparison Of Language Uses In Science And Mathematics
In this study we want to make a contribution by making a comparison between the subject languages in mathematics and science based on linguistic theories about language and language function. Through this theoretical foundation in this present study we also have the opportunity to analyze the language function and thus we can also discuss the language's role in teaching. The aim of this study is to compare and thus gain more knowledge of grammatical features in subject language in science and mathematics and how these grammatical features are used to express meaning. To fulfil this purpose, science and mathematics items from Trends in International Mathematics and Science Study (TIMSS) 2011, grade eight, have been analysed from a functional perspective on language. Empirical studies that compare language use in different subjects are sparsely present (Österholm & Bergqvist, 2013) but there are studies pointing out that how language are used to express meaning varies between different school subjects (e.g. Fang & Schleppegrell, 2008; Schleppegrell, 2004). These linguistic differences have been highlighted as arguments for a more differentiated language-based teaching of subjects, leaning on disciplinary literacy (Shanahan & Shanahan, 2008). In order to conduct such a language-based teaching of subjects, an awareness of the different functions in the language used in various school subject is of great importance. One example of a comparative language study is the corpus study conducted by Ribeck (2015) where the language in Swedish teaching materials in science is analyzed, and compared with teaching materials in social science and with textbooks in mathematics. However, Ribeck does not make a direct analysis of mathematical subject language, her focus is rather on the language used in natural science compared to social science. There are also studies that focuses on the language use within subjects. Here it appears that the subject language is used differently and has different functions in different content areas within school mathematics (e.g. Bergvall, 2016) as well as within the different school science subjects, e.g. biology, physics, chemistry and earth science (e.g. Persson, 2016).  This study draws on a social semiotic perspective and systemic functional linguistics (SFL) (Halliday & Matthiessen, 2004). A point of departure is the perspective that different registers of language are used in different social contexts, which in this study is defined as the two school subjects science and mathematics. Grounded in SFL and the three meta-functions ideational, interpersonal and textual function the meaning dimension model of analysis was developed in a previous research project (Bergvall et al., 2016; Persson et al., 2016). Four central meaning dimensions, packing, precision, personification and presentation, were condensed from previous research regarding academic language and language use in the school subjects science and mathematics. The meaning dimensions can be used as measures of how grammatical features are used in various types of texts in order to express meaning. Packing and precision are regarded as aspects of the ideational meta-function. Packing is a measure of the information density in a text and precision is a measure of how and to what extent the given information in the text is specified. Personification, as an aspect of the interpersonal meta-function, is a measure of how personal relations between the reader and the text are expressed. The last meaning dimension, presentation, concerns how the information is structured in the text and is regarded as an aspect of the textual meta-function. In the present study, the four meaning dimensions are used to describe and compare the language and its function in science and mathematics items in TIMSS 2011. Method By the use of a quantitative method all items in mathematics and science from the Swedish version of TIMSS 2011, grade eight were analyzed. This material consists of 197 items in science and 217 items in mathematics. The language in these items have been analyzed for word class, word length and number of words per items by a computer based automatic parsing. For this parsing Extensible Markup Language (XML) was used. Some other linguistic features, i.e. passive forms and subordinate clauses, were identified manually. Since the meaning dimensions are used as a base for the linguistic analysis, the results will possibly be generally applicable also for other European languages, although the analysis was conducted on the Swedish version of TIMSS items. Packing was measured by calculating the number of nouns and the number of long words (>6 characters). Precision in the items were provided by words such as adjectives, adverbs, participles and counting words specifying different attributes in the items. Personification was here measured by the number of personal pronouns and proper names and presentation was measured by the presence of subordinate clauses and passive forms. In order to compensate for the varying length of different items, the number of the different linguistic features were divided by the number of words in the particular item. To enable the adding of different features, each feature is normalized by calculating its z-score. An index was then calculated for each meaning dimension based on the linguistic information on each item. From these indices a comparison between the language uses in the two subjects was possible. In the next step of the analysis each subject were separated into content domains: Algebra, Data & chance, Geometry and Numbers for mathematics items and Biology, Chemistry, Earth science and Physics for science items. This enabled variations of language use within the subjects also to be analyzed. The results were compiled in box-plots diagrams which visualized the distribution of the expressions of the four meaning dimensions in the various content domains. Expected Outcomes Preliminary results show that central traits of the academic language as measured by the four meaning dimensions are used in similar ways in both science and mathematics. The levels of packing, precision and presentation are fairly similar when looking at differences between the subjects. Personification shows the largest differences between the subjects, where mathematics as a whole makes more use of personal pronouns and proper names in the items. When separating the subjects into content domains, Statistics shows the highest level of personification. In this domain it can therefore be concluded that human participants are essential, thus emphasizing that this is a domain that this is an area of relevance for people in general or for the student him/herself. This can be interpreted as signaling the possibility to actively participate and interact in similar situations as described by the items context. On the other hand, in domains such as Algebra, Geometry and Earth science where the content is expressed with a low level of personification, the interpretation is that the content of these domains –at least as expressed in TIMSS items- are more separated from peoples’ everyday lives and thus the students’ own reality. Another result that emerges from the analysis relates to the meaning dimension presentation where we see that the written texts, especially in Algebra, but also in Geometry, Numbers and Earth science, mainly contains short sentences without subordinate clauses. In written academic language, subordinate clauses are a common tool for creating information flow and link different parts of the text (Fang, 2006; Schleppegrell, 2004; Veel, 1997). The lack of subordinate clauses in tasks in certain content areas of TIMSS indicates a subject-specific linguistic form that may require a familiarity with this specific form of language use. References Bergvall, I. (2016). Bokstavligt, bildligt och symboliskt i skolans matematik – en studie om ämnesspråk i TIMSS. [Diss.] Uppsala: Acta Universitatis Upsaliensis. Bergvall, I., Wiksten Folkeryd, J., & Liberg, C. (2016). Linguistic features and their function in different mathematical content areas in TIMSS 2011. Nordic Studies in Mathematics Education, 21(2), 45-68. Fang, Z. (2006). The Language Demands of Science Reading in Middle School, International Journal of Science Education, 28(5) 491-520. Fang, Z., & Schleppegrell, M. J. (2008). Reading in secondary content areas: A language-based pedagogy. Ann Arbor: University of Michigan Press. Halliday, M. A. K., & Matthiessen, C. M. I. M. (2004). An introduction to functional grammar (3.th ed.). London: Arnold. Persson, Tomas (2016). De naturvetenskapliga ämnesspråken. De naturvetenskapliga uppgifterna i och elevers resultat från TIMSS 2011 år 8. [Diss.] Uppsala: Acta Universitatis Upsaliensis. Persson, T., af Geijerstam, Å., & Liberg, C. (2016). Features and functions of scientific language(s) in TIMSS 2011. Nordic Studies in Science Education, 12(2), 176-196. Ribeck, Judy (2015). Steg för steg. Naturvetenskapligt ämnesspråk som räknas. [Diss.] Data linguistica. No. 28, Institutionen för svenska språket, Göteborgs universitet. Shanahan, T., & Shanahan, C. (2008). Teaching disciplinary literacy to adolescents: Rethinking content-area literacy. Harvard Educational Review, 78(1), 40–59. Schleppegrell, M. J. (2004). The language of schooling; a functional linguistics perspective. London: Lawrence Erlbaum Associates. Veel, R. (1997). Learning How to Mean-Scientifically Speaking: Apprenticeship into Scientific Discourse in the Secondary School. In. Christie Frances & Jim R. Martin (Eds.), Genre and Institutions: Social Processes in the Workplace and School, s. 161-195. London: Cassell. Österholm, M. & Bergqvist, E. (2013). What is so special about mathematical texts? Analyses of common claims in research literature and of properties of textbooks. ZDM Mathematics education, 45(5) 751-763