Design optimization of Halbach array permanent magnet motor to achieve sensorless performance using genetic algorithm

Purpose The purpose of this paper is to investigate Halbach array effects in surface mounted permanent magnet machine (SMPM) in terms of both self-sensing and torque capabilities. A comparison between a conventional SMPM, which has radially magnetized rotor, and a Halbach machine has been carried out. Design/methodology/approach The geometric parameters of the two machines have been optimized using genetic algorithm (GA) with looking Pareto. The performance of the machines’ geometry has been calculated by finite element analysis (FEA) software, and two parametric machine models have been realized in Matlab coupled with the FEA and GA toolboxes. Outer volume of the machine, thus copper loss per volume has been kept constant. The Pareto front approach, which simultaneously considers looks two aims, has been used to provide the trade-off between the torque and sensorless performances. Findings The two machines’ results have been compared separately for each loading condition. According to the results, the superiority of the Halbach machine has been shown in terms of sensorless capability compromising torque performance. Additionally, this paper shows that the self-sensing properties of a SMPM machine should be considered at the design stage of the machine. Originality/value A Halbach machine design optimization has been presented using Pareto optimal set which provides a trade-off comparison between two aims without using weightings. These are sensorless performance and torque capability. There is no such a work about sensorless capability of the Halbach type SMPM in the literature

Observation of Vibrio mediterranei (Pujalte and Garay 1986) / Vibrio shiloi (Kushmaro et al. 2001) bacteria from skin ulcers of the cultured sea cucumber Holothuria poli (Delle Chiaje, 1823)

Skin ulcer syndrome is frequently reported as a serious disease affecting the health, growth and mortality of stocks in sea cucumber aquaculture. In this study, bacteria isolated predominantly from skin ulcers of sea cucumber Holothuria poli (Delle Chiaje, 1823), a new candidate for aquaculture in the Mediterranean, were investigated. Morphological and biochemical tests, and molecular analysis methods were used to examine the dominant bacteria in the lesions of H. poli showing skin ulceration, peristome tumour and visceral ejection symptoms in rearing tanks. Present study is the first report for isolation and identification of Vibrio mediterranei (Pujalte and Garay 1986) (called also Vibrio shiloi Kushmaro et al. 2001) as a predominant gram-negative bacterium in the skin ulcers of H. poli. Reference data provided from the present study would lead to understand possible major pathogens causing skin ulceration syndrome and is crucial for the prophylaxis and treatment of such disease in holothuriculture

Carvacrol alters soluble factors in HCT-116 and HT-29 cell lines

Background/aim: Natural products are popular insights for researchers to investigate promising anti-cancer agents since some of these substances have lesser adverse effects restricting the treatment than traditional chemotherapeutic agents. A well-known monoterpene Carvacrol, widely consumed in Mediterranean cuisine and lower risks of cancer, has efficient anticancer effects. However, the mechanism of action is yet to be discovered.Materials and methods: The investigation aims to illuminate a new perceptive in the role of this substance on colorectal cancer treatment, by the means of differences in a well-defined range of soluble factors. Carvacrol effect on both HT-29 and HCT-116 cell lines was evaluated on proliferation and the IC 50 values were calculated by the RTCA xCELLigence device. Then MAGPIX assay was performed to obtain the changes in soluble factors of the cell lines.Results: The Multiplexing assay suggests some of these factors were altered in favor of surviving and proliferation in aggressive cell line HCT-116 whereas they were altered against these characters in HT-29, were correlated with the increased IC50 concentration of HCT116 in carvacrol treatment.Conclusion: The current study indicates that differences in the levels of these soluble factors could modulate the anticancer effect related to carvacrol

TİP 1 DİYABETİ OLAN ERGENLERDE FİZİKSEL AKTİVİTE SEVİYESİ İLE DEPRESYON, ANKSİYETE, YAŞAM KALİTESİ VE BENLİK SAYGISI ARASINDAKİ İLİŞKİ

Purpose: The aim of this study was to assess the relationship between physical activity (PA) level and depression, anxiety, quality of life, self-esteem and HbA1c in adolescents with type 1 diabetes mellitus (T1DM)

Association of physical activity level with depression, anxiety, and quality of life in children with type 1 diabetes mellitus

Background: Children with type 1 diabetes mellitus (T1DM) have low physical activity levels and are at high risk for psychosocial morbidities, including depression, heightened anxiety and low health-related quality of life (HRQoL)

RELATIONSHIP BETWEEN PHYSICAL ACTIVITY LEVEL AND DEPRESSION, ANXIETY, QUALITY OF LIFE, SELF-ESTEEM, AND HBA1C IN ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS

Purpose: The aim of this study was to assess the relationship between physical activity (PA) level and depression, anxiety, quality of life, self-esteem and HbA1c in adolescents with type 1 diabetes mellitus (T1DM)

Türkiye Cumhuriyeti Diyanet İşleri Başkanlığı tarihi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Yiğit, Aslı

Neuroprotective effects of sinapic acid involve the iron regulatory role on the rotenone-induced Parkinson’s disease model

In the last decades, ferroptosis and its relationship with Parkinson’s disease have gained significant attention. Compounds that affect ferroptosis and iron-dependent pathways in particular, have possible candidates for study in this context.Sinapic acid is an iron-chelator and high antioxidant bioactive phenolic acid. Its neuroprotective action, due to the antioxidant capacity, has been shown in several experimental models.However, the relationship between iron and antioxidant actions is still misunderstood and therefore, in the current study, we tried to investigate the effects of sinapic acid in rotenone-induced Parkinson’s disease with the aspect of ferroptosis and iron-dependent alterations.The Parkinson’s disease model was induced by a single dose intrastriatal and intrategmental rotenone (5µg/µl) injection.Sinapic acid (30mg/ kg) was orally administered during a 28-day period after the Parkinson’s disease model was validated.Our results demonstrated that sinapic acid treatment attenuated rotenone-induced increase of serum transferrin and iron levels.Furthermore, sinapic acid inhibited rotenone-induced heme oxygenase-1(HO-1) increase and decrease of glutathione peroxidase-4 (GPx-4) levels in brain tissue. Also, sinapic acid treatment decreased motor impairment, likely as a result of the ameliorative effects on the tyrosine hydroxylase immunoreactivity loss after the rotenone insult.Our study suggests that the iron regulatory role of sinapic acid possibly plays a role in the protective effect on rotenone-induced neuronal damage