Self-Similar Blowup Solutions to the 2-Component Camassa-Holm Equations

In this article, we study the self-similar solutions of the 2-component Camassa-Holm equations% \begin{equation} \left\{ \begin{array} [c]{c}% \rho_{t}+u\rho_{x}+\rho u_{x}=0 m_{t}+2u_{x}m+um_{x}+\sigma\rho\rho_{x}=0 \end{array} \right. \end{equation} with \begin{equation} m=u-\alpha^{2}u_{xx}. \end{equation} By the separation method, we can obtain a class of blowup or global solutions for $\sigma=1$ or $-1$. In particular, for the integrable system with $\sigma=1$, we have the global solutions:% \begin{equation} \left\{ \begin{array} [c]{c}% \rho(t,x)=\left\{ \begin{array} [c]{c}% \frac{f\left( \eta\right) }{a(3t)^{1/3}},\text{ for }\eta^{2}<\frac {\alpha^{2}}{\xi} 0,\text{ for }\eta^{2}\geq\frac{\alpha^{2}}{\xi}% \end{array} \right. ,u(t,x)=\frac{\overset{\cdot}{a}(3t)}{a(3t)}x \overset{\cdot\cdot}{a}(s)-\frac{\xi}{3a(s)^{1/3}}=0,\text{ }a(0)=a_{0}% >0,\text{ }\overset{\cdot}{a}(0)=a_{1} f(\eta)=\xi\sqrt{-\frac{1}{\xi}\eta^{2}+\left( \frac{\alpha}{\xi}\right) ^{2}}% \end{array} \right. \end{equation} where $\eta=\frac{x}{a(s)^{1/3}}$ with $s=3t;$ $\xi>0$ and $\alpha\geq0$ are arbitrary constants.\newline Our analytical solutions could provide concrete examples for testing the validation and stabilities of numerical methods for the systems.Comment: 5 more figures can be found in the corresponding journal paper (J. Math. Phys. 51, 093524 (2010) ). Key Words: 2-Component Camassa-Holm Equations, Shallow Water System, Analytical Solutions, Blowup, Global, Self-Similar, Separation Method, Construction of Solutions, Moving Boundar

Steep sharp-crested gravity waves on deep water

A new type of steady steep two-dimensional irrotational symmetric periodic gravity waves on inviscid incompressible fluid of infinite depth is revealed. We demonstrate that these waves have sharper crests in comparison with the Stokes waves of the same wavelength and steepness. The speed of a fluid particle at the crest of new waves is greater than their phase speed.Comment: 4 pages, 2 figures, submitted to Phys. Rev. Let

Gravity travelling waves for two superposed fluid layers, one being of infinite depth: a new type of bifurcation

International audienceIn this paper, we study the travelling gravity waves in a system of two layers of perfect fluids, the bottom one being infinitely deep, the upper one having a finite thickness h. We assume that the flow is potential, and the dimensionless parameters are the ratio between densities ρ = ρ 2 /ρ 1 and λ = gh/c^2. We study special values of the parameters such that λ(1 − ρ) is near 1 − , where a bifurcation of a new type occurs. We formulate the problem as a spatial reversible dynamical system, where U = 0 corresponds to a uniform state (velocity c in a moving reference frame), and we consider the linearized operator around 0. We show that its spectrum contains the entire real axis (essential spectrum), with in addition a double eigenvalue in 0, a pair of simple imaginary eigenvalues ±iλ at a distance O(1) from 0, and for λ(1 − ρ) above 1, another pair of simple imaginary eigenvalues tending towards 0 as λ(1 − ρ) → 1 +. When λ(1 − ρ) ≤ 1 this pair disappears into the essential spectrum. The rest of the spectrum lies at a distance at least O(1) from the imaginary axis. We show in this paper that for λ(1 − ρ) close to 1 − , there is a family of periodic solutions like in the Lyapunov-Devaney theorem (despite the resonance due to the point 0 in the spectrum). Moreover, showing that the full system can be seen as a perturbation of the Benjamin-Ono equation, coupled with a nonlinear oscillation, we also prove the existence of a family of homoclinic connections to these periodic orbits, provided that these ones are not too small

Unlocking value from machines: business models and the industrial internet of things

In this article we argue that the Industrial Internet of Things (IIoT) offers new opportunities and harbors threats that companies are not able to address with existing business models. Entrepreneurship and Transaction Cost Theories are used to explore the conditions for designing nonownership business models for the emerging IIoT with its implications for sharing uncertain opportunities and downsides, and for transforming these uncertainties into business opportunities. Nonownership contracts are introduced as the basis for business model design and are proposed as an architecture for the productive sharing of uncertainties in IIoT manufacturing networks. The following three main types of IIoT-enabled business models were identified: (1) Provision of manufacturing assets, maintenance and repair, and their operation, (2) innovative information and analytical services that help manufacturing (e.g., based on artificial intelligence, big data, and analytics), and (3) new services targeted at end-users (e.g., offering efficient customization by integrating end-users into the manufacturing and supply chain ecosystem)

Genetic Evaluation of Hip Score in UK Labrador Retrievers

Hip dysplasia is an important and complex genetic disease in dogs with both genetic and environmental influences. Since the osteoarthritis that develops is irreversible the only way to improve welfare, through reducing the prevalence, is through genetic selection. This study aimed to evaluate the progress of selection against hip dysplasia, to quantify potential improvements in the response to selection via use of genetic information and increases in selection intensity, and to prepare for public provision of estimated breeding values (EBV) for hip dysplasia in the UK. Data consisted of 25,243 single records of hip scores of Labrador Retrievers between one and four years old, from radiographs evaluated between 2000 and 2007 as part of the British Veterinary Association (BVA) hip score scheme. A natural logarithm transformation was applied to improve normality and linear mixed models were evaluated using ASREML. Genetic correlations between left and right scores, and total hip scores at one, two and three years of age were found to be close to one, endorsing analysis of total hip score in dogs aged one to three as an appropriate approach. A heritability of 0.35±0.016 and small but significant litter effect (0.07±0.009) were estimated. The observed trends in both mean hip score and mean EBV over year of birth indicate that a small genetic improvement has been taking place, approximately equivalent to avoiding those dogs with the worst 15% of scores. Deterministic analysis supported by simulations showed that a 19% greater response could be achieved using EBV compared to phenotype through increases in accuracy alone. This study establishes that consistent but slow genetic improvement in the hip score of UK Labrador Retrievers has been achieved over the previous decade, and demonstrates that progress may be easily enhanced through the use of EBVs and more intense selection

Functional Polymorphisms Associated with Disease-Free Survival in Resected Carcinoma of the Esophagus

Purpose: The aim of this study was to determine whether clinical outcome after surgical resection of esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) could be predicted by functional polymorphisms in different proto-oncogenes and tumor suppressor genes. Experimental De

Single-molecule experiments in biological physics: methods and applications

I review single-molecule experiments (SME) in biological physics. Recent technological developments have provided the tools to design and build scientific instruments of high enough sensitivity and precision to manipulate and visualize individual molecules and measure microscopic forces. Using SME it is possible to: manipulate molecules one at a time and measure distributions describing molecular properties; characterize the kinetics of biomolecular reactions and; detect molecular intermediates. SME provide the additional information about thermodynamics and kinetics of biomolecular processes. This complements information obtained in traditional bulk assays. In SME it is also possible to measure small energies and detect large Brownian deviations in biomolecular reactions, thereby offering new methods and systems to scrutinize the basic foundations of statistical mechanics. This review is written at a very introductory level emphasizing the importance of SME to scientists interested in knowing the common playground of ideas and the interdisciplinary topics accessible by these techniques. The review discusses SME from an experimental perspective, first exposing the most common experimental methodologies and later presenting various molecular systems where such techniques have been applied. I briefly discuss experimental techniques such as atomic-force microscopy (AFM), laser optical tweezers (LOT), magnetic tweezers (MT), biomembrane force probe (BFP) and single-molecule fluorescence (SMF). I then present several applications of SME to the study of nucleic acids (DNA, RNA and DNA condensation), proteins (protein-protein interactions, protein folding and molecular motors). Finally, I discuss applications of SME to the study of the nonequilibrium thermodynamics of small systems and the experimental verification of fluctuation theorems. I conclude with a discussion of open questions and future perspectives.Comment: Latex, 60 pages, 12 figures, Topical Review for J. Phys. C (Cond. Matt

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

Background:Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in FGFR1, FGFR3, FGFR4 and FGFRL1 in the Breast Cancer Association Consortium. Methods:Data were combined from 49 studies, including 53 835 cases and 50 156 controls, of which 89 050 (46 450 cases and 42 600 controls) were of European ancestry, 12 893 (6269 cases and 6624 controls) of Asian and 2048 (1116 cases and 932 controls) of African ancestry. Associations with risk of breast cancer, overall and by disease sub-type, were assessed using unconditional logistic regression. Results:Little evidence of association with breast cancer risk was observed for SNPs in the FGF receptor genes. The strongest evidence in European women was for rs743682 in FGFR3; the estimated per-allele odds ratio was 1.05 (95 confidence interval=1.02-1.09, P=0.0020), which is substantially lower than that observed for SNPs in FGFR2. Conclusion:Our results suggest that common variants in the other FGF receptors are not associated with risk of breast cancer to the degree observed for FGFR2. © 2014 Cancer Research UK