263 research outputs found
Strategies and challenges to facilitate situated learning in virtual worlds post-Second Life
Virtual worlds can establish a stimulating environment to support a situated learning approach in which students simulate a task within a safe environment. While in previous years Second Life played a major role in providing such a virtual environment, there are now more and more alternative—often OpenSim-based—solutions deployed within the educational community. By drawing parallels to social networks, we discuss two aspects: how to link individually hosted virtual worlds together in order to implement context for immersion and how to identify and avoid “fake” avatars so people behind these avatars can be held accountable for their actions
The Academics Athletics Trade-off: Universities and Intercollegiate Athletics
This analysis focuses on several key issues in the Football Bowl Subdivision (FBS). The intrinsic benefits of athletic programs are discussed in the first section. Trends in graduation rates and academic performance among athletes and how they correlate with the general student body are discussed in the second section. Finally, an overview of the revenues and expenses of athletic department budgets are discussed in an effort to gain a better understanding of the allocation of funds to athletics. In spite of recent growth in revenues and expenses, the athletic department budget comprises on average only 5 percent of the entire university budget at an FBS school, though spending and revenues have increased dramatically in recent years. In the grand scheme of things, American higher education faces several other, arguably more pressing, areas of reform. However, athletics is a significant and growing dimension of higher education that warrants in-depth examination
Risk sharing arrangements for pharmaceuticals: potential considerations and recommendations for European payers
<p>Abstract</p> <p>Background</p> <p>There has been an increase in 'risk sharing' schemes for pharmaceuticals between healthcare institutions and pharmaceutical companies in Europe in recent years as an additional approach to provide continued comprehensive and equitable healthcare. There is though confusion surrounding the terminology as well as concerns with existing schemes.</p> <p>Methods</p> <p>Aliterature review was undertaken to identify existing schemes supplemented with additional internal documents or web-based references known to the authors. This was combined with the extensive knowledge of health authority personnel from 14 different countries and locations involved with these schemes.</p> <p>Results and discussion</p> <p>A large number of 'risk sharing' schemes with pharmaceuticals are in existence incorporating both financial-based models and performance-based/outcomes-based models. In view of this, a new logical definition is proposed. This is "<it>risk sharing' schemes should be considered as agreements concluded by payers and pharmaceutical companies to diminish the impact on payers' budgets for new and existing schemes brought about by uncertainty and/or the need to work within finite budgets</it>". There are a number of concerns with existing schemes. These include potentially high administration costs, lack of transparency, conflicts of interest, and whether health authorities will end up funding an appreciable proportion of a new drug's development costs. In addition, there is a paucity of published evaluations of existing schemes with pharmaceuticals.</p> <p>Conclusion</p> <p>We believe there are only a limited number of situations where 'risk sharing' schemes should be considered as well as factors that should be considered by payers in advance of implementation. This includes their objective, appropriateness, the availability of competent staff to fully evaluate proposed schemes as well as access to IT support. This also includes whether systematic evaluations have been built into proposed schemes.</p
Exploring motivations for the use of bitcoin technology
This paper presents an exploratory study focusing on user experience with Bitcoin technology. We describe interviews with 9 Bitcoin users and report findings related to users’ motivations for buying and using bitcoins. Our initial findings capture three main motivations such as Bitcoin’s predicted role in a monetary revolution, users’ increased empowerment, and their perception of real value of Bitcoin currency. We conclude with reflections on the value of these findings for HCI researchers
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Spectators’ Negotiations of Risk, Masculinity and Performative Mobilities at the TT Races
This paper explores the particular assemblage of place, event and individual identity performances that occur each year in the Isle of Man in and through the TT (Tourist Trophy) motorcycle races. These road races are associated with a high degree of risk for the racers and the confluence of over 30,000 visitors and 10,000 motorcycles also presents potential risks for spectators and residents alike. Both motorcycling and risk-taking have been associated with particular forms of masculinity, notably hegemonic, working class and youthful masculinities. Using detailed surveys of spectators we argue that the TT races, while undoubtedly
dominated by men and predicated on a cultural privileging of speed and skill, are grounded in varying combinations of determinate and reflexive attitudes to risk, reflecting the performance of a variety of gendered, ‘biker’ and wider identity-based positionalities. Findings also highlight a particular inter-relation of mobilities and place identities at the TT races and bring to light the highly significant and under-researched embodied, performative and emotional mobilities of spectators. The conceptual and methodological importance of (a) situated research of both mobilities and gender in specific place-temporalities and (b) wider surveys of motorcyclists to complement ethnographic studies of small cohorts are also stressed
Nature documentaries as catalysts for change: Mapping out the 'Blackfish Effect'
It is essential for us to understand what drives human behaviour if we want to tackle anthropogenic damage to the environment. Popular media can play an important role in shaping public attitudes, behaviours and norms towards wildlife, and documentaries in particular have become an increasingly prominent tool for social change. There is, however, a need for robust impact evaluation both in documentary-making and in conservation, to refine future interventions. The 2013 documentary Blackfish portrayed human–orca interactions at the US-based marine park, SeaWorld. Following its release, SeaWorld suffered financial difficulties and the company underwent structural changes, including a cessation of its orca breeding programme. These impacts have often been attributed to the Blackfish documentary, but little evidence has been provided to justify these claims. We combined an analysis of stock market data and semi-structured interviews with 26 key informants to build an in-depth contribution analysis. We used General Elimination Methodology, a qualitative impact evaluation methodology to build an understanding of the impact of Blackfish. We found a consensus among stakeholder groups that Blackfish induced negative publicity for SeaWorld and a change in people's perceptions of captivity. As a result, attendance at the park decreased and the market value of the company dropped. Blackfish catalysed a whole movement against marine mammal captivity. There were three key factors that led to its impact: the support from major distribution channels which allowed it to reach major audiences, emotional impact of the content and timing of its release. Blackfish benefitted from a perfect storm, building upon decades of activism to create an appropriate cultural climate for its release in 2013
US public opinion regarding proposed limits on resident physician work hours
<p>Abstract</p> <p>Background</p> <p>In both Europe and the US, resident physician work hour reduction has been a source of controversy within academic medicine. In 2008, the Institute of Medicine (IOM) recommended a reduction in resident physician work hours. We sought to assess the American public perspective on this issue.</p> <p>Methods</p> <p>We conducted a national survey of 1,200 representative members of the public via random digit telephone dialing in order to describe US public opinion on resident physician work hour regulation, particularly with reference to the IOM recommendations.</p> <p>Results</p> <p>Respondents estimated that resident physicians currently work 12.9-h shifts (95% CI 12.5 to 13.3 h) and 58.3-h work weeks (95% CI 57.3 to 59.3 h). They believed the maximum shift duration should be 10.9 h (95% CI 10.6 to 11.3 h) and the maximum work week should be 50 h (95% CI 49.4 to 50.8 h), with 1% approving of shifts lasting >24 h (95% CI 0.6% to 2%). A total of 81% (95% CI 79% to 84%) believed reducing resident physician work hours would be very or somewhat effective in reducing medical errors, and 68% (95% CI 65% to 71%) favored the IOM proposal that resident physicians not work more than 16 h over an alternative IOM proposal permitting 30-h shifts with ≥5 h protected sleep time. In all, 81% believed patients should be informed if a treating resident physician had been working for >24 h and 80% (95% CI 78% to 83%) would then want a different doctor.</p> <p>Conclusions</p> <p>The American public overwhelmingly favors discontinuation of the 30-h shifts without protected sleep routinely worked by US resident physicians and strongly supports implementation of restrictions on resident physician work hours that are as strict, or stricter, than those proposed by the IOM. Strong support exists to restrict resident physicians' work to 16 or fewer consecutive hours, similar to current limits in New Zealand, the UK and the rest of Europe.</p
The impact of mass gatherings and holiday traveling on the course of an influenza pandemic: a computational model
<p>Abstract</p> <p>Background</p> <p>During the 2009 H1N1 influenza pandemic, concerns arose about the potential negative effects of mass public gatherings and travel on the course of the pandemic. Better understanding the potential effects of temporal changes in social mixing patterns could help public officials determine if and when to cancel large public gatherings or enforce regional travel restrictions, advisories, or surveillance during an epidemic.</p> <p>Methods</p> <p>We develop a computer simulation model using detailed data from the state of Georgia to explore how various changes in social mixing and contact patterns, representing mass gatherings and holiday traveling, may affect the course of an influenza pandemic. Various scenarios with different combinations of the length of the mass gatherings or traveling period (range: 0.5 to 5 days), the proportion of the population attending the mass gathering events or on travel (range: 1% to 50%), and the initial reproduction numbers R<sub>0 </sub>(1.3, 1.5, 1.8) are explored.</p> <p>Results</p> <p>Mass gatherings that occur within 10 days before the epidemic peak can result in as high as a 10% relative increase in the peak prevalence and the total attack rate, and may have even worse impacts on local communities and travelers' families. Holiday traveling can lead to a second epidemic peak under certain scenarios. Conversely, mass traveling or gatherings may have little effect when occurring much earlier or later than the epidemic peak, e.g., more than 40 days earlier or 20 days later than the peak when the initial R<sub>0 </sub>= 1.5.</p> <p>Conclusions</p> <p>Our results suggest that monitoring, postponing, or cancelling large public gatherings may be warranted close to the epidemic peak but not earlier or later during the epidemic. Influenza activity should also be closely monitored for a potential second peak if holiday traveling occurs when prevalence is high.</p
Using NHANES oral health examination protocols as part of an esophageal cancer screening study conducted in a high-risk region of China
<p>Abstract</p> <p>Background</p> <p>The oral health status of rural residents in the People's Republic of China has not been extensively studied and the relationship between poor oral health and esophageal cancer (EC) is unclear. We aim to report the oral health status of adults participating in an EC screening study conducted in a rural high-risk EC area of China and to explore the relationship between oral health and esophageal dysplasia.</p> <p>Methods</p> <p>National Health and Nutrition Examination Survey (NHANES) oral health examination procedures and the Modified Gingival Index (MGI) were used in a clinical study designed to examine risk factors for esophageal cancer and to test a new esophageal cytology sampling device. This study was conducted in three rural villages in China with high rates of EC in 2002 and was a collaborative effort involving investigators from the National Institutes of Health and the Cancer Institute of the Chinese Academy of Medical Sciences.</p> <p>Results</p> <p>Nearly 17% of the study participants aged 40–67 years old were edentulous. Overall, the mean number of adjusted missing teeth (including third molars and retained dental roots) was 13.8 and 35% had 7 contacts or less. Women were more likely to experience greater tooth loss than men. The average age at the time of first tooth loss for those with no posterior functional contacts was approximately 41 years for men and 36 years for women. The mean DMFT (decayed, missing, and filled teeth) score for the study population was 8.5. Older persons, females, and individuals having lower educational attainment had higher DMFT scores. The prevalence of periodontal disease (defined as at least one site with 3 mm of attachment loss and 4 mm of pocket depth) was 44.7%, and 36.7% of the study participants had at least one site with 6 mm or more of attachment loss. Results from a parsimonious multivariate model indicate that participants with poor oral health wemore likely to have esophageal dysplasia (OR = 1.59; 95% CI 1.06, 2.39).</p> <p>Conclusion</p> <p>This report describes the first use of NHANES oral health protocols employed in a clinical study conducted outside of the United States. The extent and severity of poor oral health in this Chinese study group may be an important health problem and contributing factor to the prevalence of EC.</p
Efeitos da terapia ultrassônica de baixa intensidade sobre o infarto agudo do miocárdio em ratos
Introdução. O infarto agudo do miocárdio (IAM) é considerado importante causa de morbidade e mortalidade no mundo e no Brasil. Novas intervenções terapêuticas estão sendo testadas isoladas ou em associação com as já existentes com o intuito de impedir a progressão ou atenuar o remodelamento no coração infartado. Dentre elas destaca-se a aplicação do Ultra-som (US) conjunto com agentes trombolíticos. Entretanto, na aplicação da energia ultrassônica como terapêutica pós-infarto é avaliado somente o seu possível efeito como agente trombolítico, não sendo investigado a sua possível implicação no processo de cicatrização da área infartada e parâmetros funcionais cardíacos. Objetivos. Diante dessas informações, nós objetivamos avaliar os efeitos da terapia ultrassônica transtorácica não-invasiva de baixa intensidade (NITUS) sobre a morfologia e função do músculo cardíaco de ratos infartados cirurgicamente após o 5° e 30° dia. Metodologia. Ratos machos Wistar (200-250g) foram pesados e divididos aleatoriamente em oito grupos com oito animais em cada grupo. Quatro grupos de animais foram submetidos à indução do IAM através da oclusão permanente da artéria coronária descendente anterior esquerda, sendo que dois destes grupos foram sacrificados no 5° dia após o IAM e as cinco aplicações da terapia ultrassônica e os outros dois grupos foram sacrificados no 30° dia após o IAM e as 5 aplicações da terapia ultrassônica. Quatro grupos de animais foram submetidos à cirurgia fictícia (Sham), sendo que dois destes grupos foram sacrificados no 5° dia após a cirurgia fictícia e as 5 aplicações da terapia ultrassônica e os outros dois grupos foram sacrificados no 30° dia após a cirurgia fictícia e as 5 aplicações da terapia ultrassônica. Os parâmetros da terapia ultrassônica foram freqüência de 1MHz, potência de 1W/cm2, modo pulsado e tempo de aplicação de 5 minutos. Para avaliação dos parâmetros funcionais foi realizado registros hemodinâmicos de todos os grupos e após a coleta dos registros os corações foram retirados para análise morfométrica a fim de avaliar a área da cicatriz do infarto. Os corações foram cortados em 4 fatias sendo retirados 3 cortes com espessura de 8 micrômetros da terceira fatia do ápice para a base, e estes foram corados com picrosírius. Foi utilizada uma câmera de vídeo para capturar uma área que contivesse todo o corte. A imagem era capturada com a utilização do programa AMCap e após a captura, esta era arquivada. A imagem arquivada era transferida para o programa ImageJ 1.42q/java no qual era marcada a área da cicatriz. De modo semelhante, era marcada toda a área da parede ventricular, para se obter a relação entre a área da cicatriz e a área total da parede ventricular. Resultados. No que concerne aos parâmetros hemodinâmicos, observamos que 30 dias após o IAM houve redução na pressão diastólica final (PDF) (mmHg) do grupo IAM+US quando comparado com grupo IAM (15±1.9 e 26±1.4; p<0.01 respectivamente). Não houve diferença significativa na área da cicatriz do infarto entre os grupos IAM e IAM+US no 5º. dia após infarto (31.6%±3.1% e 34.5%±1.6, respectivamente). Houve redução da área da cicatriz do infarto no grupo IAM+US quando comparado ao grupo IAM (21.5%±1.4% e 26.2%±1.7%; p<0.05, respectivamente) no 30º dia após IAM. Conclusão. A terapia com US dentro dos parâmetros estabelecidos, reduziu a área da cicatriz do infarto no grupo IAM+US (30 dias) bem como manteve a PDF dentro de valores fisiológicos, provavelmente por exercer influência nas fases inflamatória, proliferativa e de remodelamento, o que favorece um aumento na velocidade da resposta inflamatória por meio da mobilização de células inflamatórias como neutrófilos, macrófagos, ao mesmo tempo em que estimulou à degranulação dos mastócitos, bem como interferiu na mobilização leucocitária
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