Biomarker Toksisitas: Paparan Logam Tingkat Molekuler

Sebuah buku yang menyajikan solusi bagi siapapun yang mempelajari konsep-konsep bahaya paparan logam pada kesehatan manusia

Protein Lendir Bekicot Achatina Fullica Ferussac (Achasin) Galur Jawa Sebagai Cairan Antibakteri

Hak Paten Protein Lendir Bekicot Achatina Fullica Ferussac (Achasin) Galur Jawa Sebagai Cairan Antibakter

Microbiological Studies on the Production of Antimicrobial Agent by Saponin Aloe vera Linn against Streptococcus sanguinis

vitro against Streptococcus sanguinis. Streptococcus sanguinis, is a gram-positive bacteria mostly found in dental plaque. Mechanical plaque control by brushing is the most effective method for controlling plaque and also gingivitis. Saponins Aloe vera L, natural materials for the treatment and prevention of disease is a strong surface active compounds, considered as, one of the toothpaste composition and more acceptable by the body. Saponins or SLS induce to Streptococcus sanguinis bacteria and the minimal bactericidal concentrations determined by dilution method. The TEM is used, to evaluate the essential cellular function of Streptococcus sanguinis inhibited by the primary saponin-target interaction, whether they induce cell death (bactericidal drugs) or merely inhibit cell growth (bacteriostatic drugs). The variation morphological changes of bacterial cell, which is attributed to a whole cell wall with opaque cytoplasmic, cell wall separated from plasma membrane, plasma membrane rupture and event the cell wall peeled off revealed on the assays. Saponin Aloe vera L., extract was active against Streptococcus sanguinis with minimal inhibitory concentration value of 3.125%. The control group SLS killed Streptococcus sanguinis with minimal inhibitory concentration value of 0.78% in all repetitions. Saponin fraction Aloe vera L. can inhibit the growth of Streptococcus sanguinis at concentration of at least 3.125%

Phytochemicals potential of Cyperus rotundus Linn. root extract Kalimantan for treatment of Oral mucosa traumatic ulcer: "Healing process enhancement with Cyperus rotundus L. root"

Abstract: Cyperus(C.) rotundus Linn(L.) root extract Kalimantan have been shown empirically for decades as a medicine for the treatment of toothache, swollen gums and thrush in the Island of Borneo (Kalimantan). This study was aimed to analyze the phytoconstituents of C. rotundus L. root extract and the effect of its concentration in inducing the expression of TGF-β 1 and the fibroblasts proliferation in the healing process of oral mucosa traumatic ulcer in Wistar rats. Materials and Methods: This was an experimental study with randomized post test only control group design. The gel extract of C. rotundus L. based 3% Natrium carboxymethyl celluose (CMC-Na) made by maceration method was used as treatment group while gel-based 3% CMC-Na was used for control group. Fortyeight rats were divided equally into two groups. Twenty-four rats were observed on day 5 and 24 others on day 7. Histological evaluation was performed by Hematoxylin Eosin (HE) stai ning for fibroblast and Immunohistochemistry(IHC) staining for TGF-β 1. Statistical analysis was performed using One Way Anova and Post Hoc Tukey's Honestly Significant Difference (HSD) test. Results:C. rotundus L. gel extract showed significant difference between the groups as a whole and between each group. The 4% was the best concentration compared to 2% and 8% of C. rotundus L. based 3% CMC-Na. There were strong correlation between TGF-β 1 expression and the number of fibroblasts. Conclusion: The concentration of four percent C. rotundus L. root extract Kalimantan, effectively increases the expression of TGF-?1, triggers migration and increases the proliferation of fibroblasts, which ultimately increases the amount of fibroblasts in the wound area

Analysis of Dentist’s Working Posture and Lactic Acid Level on the Risk of Musculoskeletal Disorders

the aims of study was to determine the relationship betweenthe working osture and leatie acid levels on the risk of MSDs of dentist working in the health center surabaya

Dentist’s Working Posture and Glucosa Level on the Risk of Musculoskeletal Disorders

Introduction: Ergonomics good work is important so that workability, efficiency and a high level of clinical treatment can be maintained throughout the working life of a dentist. The success of the application ensures high productivity, avoid illness and injury, and improve satisfaction among dentist. On the other hand, the application of which is not suitable can cause musculoskeletal disorders related to work. MSD prevalence of dentists in the world is quite high, in India 78%, and Turkey reached 94%. The aim of the study was to determine the relationship between the dentist’s working posture and levels of glucose on the risk of MSD among dentist in the Surabaya Health Center. Method: The study design was an analytical observational with cross sectional approach conducted at the working dentist, filled maxillary posterior teeth. The sampling technique was using cluster random sampling with sample number of 19 subjects. RULA method was used to analyzed working posture of the subject while MSD complaint were recorded using Nordic Body Map. Data are coded and entered into the tabulation prior to analysis using a statistical test to see the correlation. Basic statistics are calculated, including the prevalence rate. Results and discussion: There was a relationship between the glucose levels with Nordic Body Map with significant value p= 0.025. While the significant relationship between the Dentist’t working posture and Nordic Body Map was p=0.012

Effects of Occupational Environmental Controls on the Level of Co, Ni and Cr among Dental Technicians

Dental laboratory technicians may be exposed to metal alloys that are used in the production of crowns, bridges and removable partial dentures. The aim of this study was to assess whether dental technicians are occupationally exposed to Cobalt, Nickel and Chromium by analyzing the concentration of Cobalt, Nickel and Chromium in the blood level and to investigate the effects of occupational environmental controls associated with dental prostheses production in dental laboratories in East Java Indonesia. Result found shows that the concentration of Cobalt, Nickel and Chromium in the blood level of dental technicians are higher than the certified reference material level recommended. The concentration of Cobalt, Nickel and Chromium in the dental technicians’ blood level are 27 μg/L, 37 μg/L and 117 μg/L respectively. Although 50% of dental laboratories surveyed had ventilator and air dust respirator, almost all of the technicians did not do personal occupational environmental controls correctly

Correlation between working position of dentists and malondialdehyde concentration with musculoskeletal complaints

Background: Musculoskeletal complainstof dentists have become common issues in dentistry since the awkward positions during treating the patients; such as position of a dentist who bends towards the patient, moving abruptly, twisting the body from a side to another side. All those movements are done several times in long term. Such high level of activity without sufficient recovery time may lead to an oxidative stress, so it will affect on the musculoskeletal and concentration of malondialdehyde (MDA) in blood. Purpose: The purpose of this study was to identify the correlation between MDA concentration on the risk of musculoskeletal complaint on dentist with working position of maxilla dental patching at community health center(Puskesmas) in Surabaya. Method: This study was observational analytics using cross sectional approach with cluster random sampling technique. The total samples were 19. Musculoskeletal complains assesment is conducted using a Nordic body map questionaire that devided into 4 scores. Working position of samples were asseses using Ovako working posture analysis (OWAS). Bloos sampling was conducted to examine the concentration of MDA. Result: From data analysis result using Spearman correlation test, it was found that there was a significant correlation between working position and musculoskeletal complaint using Spearman correlation test and the p value obtained was<0.05. This research also found that there was a significant correlation between malondialdehyde concentration and musculoskeletal complaint using Pearson correlation test and the p value obtained was <0.05. Conclusion: There was a correlation between working positions of dentists and musculoskeletal complaints. There was a correlation between working position and MDA concentration with the musculoskeletal complaints

Analysis of Dentist’s Working Posture and Lactic Acid Level on the Risk of Musculoskeletal Disorders

the aims of study was to determine the relationship betweenthe working osture and leatie acid levels on the risk of MSDs of dentist working in the health center surabaya