Theorising how art gallery interventions impact people with dementia and their caregivers

Dementia refers to a variety of diseases that are characterised by cognitive difficulties and an overall decline in daily living skills. Psychologically-informed arts and health programmes may be particularly beneficial ways of improving the lives of people with dementia and their caregivers. This study sought to better understand how programmes at contemporary and traditional art galleries might play a role in the lives of people with dementia. Participants included 12 people with mild to moderate dementia, their 12 caregivers and 4 gallery facilitators. Those with dementia and their caregivers were engaged in art-viewing followed by art-making over an 8 week period. Data, collected through post-intervention interviews with participants, field notes and extensive written communication between the facilitators and research team, were analysed using grounded theory methodology to theorise how gallery-based interventions affect people with dementia and those who care for them. The emerging theory has four primary components: the art gallery is seen as being a physically-valued place that provides intellectual stimulation and offers opportunities for social inclusion that can change how dementia is perceived. These components coalesced to create positive emotional and relational effects for those with dementia and caregivers. The resulting theory has potential implications for the use of gallery-based programmes in dementia care within public health, healthcare and museum/art gallery policy and practice

Viewing and making art together: an eight-week gallery-based intervention for people with dementia and their caregivers

Objectives: This is the first known study that sought to understand the experience of an eight-week art-gallery-based intervention offered at two distinctly different galleries for people with mild to moderate dementia and their carers. The study examined impact on social inclusion, carer burden, and quality of life and daily living activities for a person with dementia. Method: A mixed-methods pre-post design using standardised questionnaires and interviews involved 24 participants (12 with dementia) and compared similar interventions at a traditional and a contemporary art gallery. Qualitative data was analysed using thematic analysis. Results: No significant pre-post difference was found between the traditional or contemporary gallery groups on quantitative measures. There was, however, a non-significant trend towards a reduction in carer burden over the course of the intervention for both gallery groups. Thematic analysis revealed well-being benefits from both traditional and contemporary art gallery sites that included positive social impact resulting from feeling more socially included, self-reports of enhanced cognitive capacities for people with dementia, and an improved quality of life. Conclusion: Participants were unanimous in their enjoyment and satisfaction with the programme, despite the lack of significance from standardised measures. Further consideration of art galleries and museums, as non-clinical community resources for dementia care, is warranted. The interventions at both galleries helped to foster social inclusion and social engagement, enhance the caring relationship between the carers and PWD, support the personhood of PWD, and stimulate cognitive processes of attention and concentration

Muscle protein and glycogen responses to recovery from hypogravity and unloading by tail-cast suspension

Previous studies in this laboratory using the tail-bast hindlimb suspension model have shown that there are specific changes in protein and carbohydrate metabolism in the soleus muscle due to unloading. For example, 6 days of unloading caused a 27% decrease in mass and a 60% increase in glycogen content in the soleus muscle, while the extensor digitorum longus muscle was unaffected. Also, fresh tissue tyrosine and its in vitro release from the muscle are increased in the unloaded soleus, indicating that this condition causes a more negative protein balance. With these results in mind, studies to investigate the effect of hypogravity on protein and carbohydrate metabolism in a number of rat hindlimb muscles were carried out

The impact of viewing and making art on verbal fluency and memory in people with dementia in an art gallery setting

Dementia is a progressive disease characterized by a widespread impairment of mental functioning including cognitive skills. Research has suggested that the arts can have positive effects in terms of physical and mental health for people with a dementia. The present study sought to identify the impact of art-making and art-viewing activities, within the context of a publicly accessible art gallery, on verbal fluency and memory. Thirteen participants diagnosed with early to mid-stage dementia participated, along with their caregivers, in 8-week long art-viewing and art-making groups at an art gallery in the United Kingdom. Audio recordings of sessions were transcribed and analysed using quantitative content analysis. Findings suggested that the interventions described did not negatively affect cognitive ability in the dimensions measured and the data hints that improvements are possible. The results provide support for further controlled studies examining the impact of visual art, aesthetics, and art gallery-based programmes on cognition in people with dementia. Further research is required to address the methodological limitations presented in the current study

Scattering in Multilayered Structures: Diffraction from a Nanohole

The spectral expansion of the Green's tensor for a planar multilayered structure allows us to semi analytically obtain the angular spectrum representation of the field scattered by an arbitrary dielectric perturbation present in the structure. In this paper we present a method to find the expansion coefficients of the scattered field, given that the electric field inside the perturbation is available. The method uses a complete set of orthogonal vector wave functions to solve the structure's vector wave equation. In the two semi-infinite bottom and top media, those vector wave functions coincide with the plane-wave basis vectors, including both propagating and evanescent components. The technique is used to obtain the complete angular spectrum of the field scattered by a nanohole in a metallic film under Gaussian illumination. We also show how the obtained formalism can easily be extended to spherically and cylindrically multilayered media. In those cases, the expansion coefficients would multiply the spherical and cylindrical vector wave functions.Comment: 9 pages, 5 figure

A High-Order, Linear Time-Invariant Model for Application to Higher Harmonic Control and Flight Control System Interaction

This research describes a new methodology for the extraction of a high-order, linear time invariant model, which allows the periodicity of the helicopter response to be accurately captured. This model provides the needed level of dynamic fidelity to permit an analysis and optimization of the AFCS and HHC algorithms. The key results of this study indicate that the closed-loop HHC system has little influence on the AFCS or on the vehicle handling qualities, which indicates that the AFCS does not need modification to work with the HHC system. However, the results show that the vibration response to maneuvers must be considered during the HHC design process, and this leads to much higher required HHC loop crossover frequencies. This research also demonstrates that the transient vibration responses during maneuvers can be reduced by optimizing the closed-loop higher harmonic control algorithm using conventional control system analyses

Second specimen of the Late Cretaceous sauropod dinosaur Diamantinasaurus matildae provides new anatomical information on skull and neck evolution in early titanosaurs and the biogeographic origins of Australian dinosaur faunas

The titanosaurian sauropod dinosaur Diamantinasaurus matildae is represented by two individuals from the Cenomanian–lower Turonian ‘upper’ Winton Formation of central Queensland, north-eastern Australia. The type specimen has been described in detail, whereas the referred specimen, which includes several elements not present in the type series (partial skull, atlas, axis and postaxial cervical vertebrae), has only been described briefly. Herein, we provide a comprehensive description of this referred specimen, including a thorough assessment of the external and internal anatomy of the braincase, and identify several new autapomorphies of D. matildae. Via an expanded data matrix consisting of 125 taxa scored for 552 characters, we recover a close, well-supported relationship between Diamantinasaurus and its contemporary, Savannasaurus elliottorum. Unlike previous iterations of this data matrix, under a parsimony framework we consistently recover Diamantinasaurus and Savannasaurus as early-diverging members of Titanosauria using both equal weighting and extended implied weighting, with the overall topology largely consistent between analyses. We erect a new clade, named Diamantinasauria herein, that also includes the contemporaneous Sarmientosaurus musacchioi from southern Argentina, which shares several cranial features with the referred Diamantinasaurus specimen. Thus, Diamantinasauria is represented in the mid-Cretaceous of both South America and Australia, supporting the hypothesis that some titanosaurians, in addition to megaraptoran theropods and possibly some ornithopods, were able to disperse between these two continents via Antarctica. Conversely, there is no evidence for rebbachisaurids in Australia, which might indicate that they were unable to expand into high latitudes before their extinction in the Cenomanian–Turonian. Likewise, there is no evidence for titanosaurs with procoelous caudal vertebrae in the mid-Cretaceous Australian record, despite scarce but compelling evidence for their presence in both Antarctica and New Zealand during the Campanian–Maastrichtian. These later titanosaurs presumably dispersed into these landmasses from South America before the Campanian (~85 Mya), when seafloor spreading between Zealandia and Australia commenced. Although Australian mid-Cretaceous dinosaur faunas appear to be cosmopolitan at higher taxonomic levels, closer affinities with South America at finer scales are becoming better supported for sauropods, theropods and ornithopods

pShuffle: A Plasmid for in vitro Evolution

Multi-gene shuffling is a powerful method used to combine and optimize attributes of various proteins. Here we report on the design and construction of the plasmid “pShuffle” which is suited for a variety of in vitro DNA-recombination techniques. The multiple cloning site (MCS) of pShuffle was designed to allow for the cloning of genes as well as their expression under control of either a lac- or a T7-promoter. As a specific feature, this MCS allows for the fusion of special linker sequences to both ends of cloned genes. After subsequent DNA-recombination steps, these linkers facilitate reamplification of generated gene variants, and thus may be used to construct clone libraries for activity screenings. The suitability of pShuffle for multi-gene shuffling applications was further shown with a set of styrene monooxygenase genes originating from proteo- and actinobacteria

Electron-hole and plasmon excitations in 3d transition metals: Ab initio calculations and inelastic x-ray scattering measurements

We report extensive all-electron time-dependent density-functional calculations and nonresonant inelastic x-ray scattering measurements of the dynamical structure factor of 3d transition metals. For small wave vectors, a plasmon peak is observed which is well described by our calculations. At large wave vectors, both theory and experiment exhibit characteristic low-energy electron-hole excitations of d character which correlate with the presence of d bands below and above the Fermi level. Our calculations, which have been carried out in the random-phase and adiabatic local-density approximations, are found to be in remarkable agreement with the measured dynamical structure factor of Sc and Cr at energies below the semicore onset energy (M-edge) of these materials.Comment: To appear in Phys. Rev.