Performance of boilers equipped with vapor-pump (BEVP) system equipped with a novel air-flue gas total heat exchanger

Because of high humidity and nonlinearity of flue gas, waste heat from flue gas is hard to recovery. Boilers equipped with vapor-pump system is developed to solve the problem caused by high humidity. In this system, double spray towers subsystem is equipped to realize total heat waste heat recovery. However, caused by nonlinearity, limited waste heat recovery efficiency is just 83 % (1 segment) and 93 % (2 segment). Further, based on boilers equipped with vapor-pump (BEVP) system, enthalpy wheel system is developed to solve the problem caused by nonlinearity. However, enthalpy wheel system cannot solve the problem completely. In this article, a novel air-flue gas total heat exchanger is put forward to achieve full waste heat recovery. In this system, waste heat recovery efficiency limit is up to 100 %. Then, the limit condition of total heat transfer process is discussed. Performance of the total heat exchanger is discussed and compared to double spray towers system and enthalpy wheel system. As the result, considering heat transfer temperature difference, the total heat exchanger total heat transfer efficiency of the total heat exchanger is 7 % higher than 2-segment BEVP system and 10 % higher than enthalpy wheel system.</p

The impact of mouth breathing on dentofacial development: A concise review

Mouth breathing is one of the most common deleterious oral habits in children. It often results from upper airway obstruction, making the air enter completely or partially through oral cavity. In addition to nasal obstruction caused by various kinds of nasal diseases, the pathological hypertrophy of adenoids and/or tonsils is often the main etiologic factor of mouth breathing in children. Uncorrected mouth breathing can result in abnormal dental and maxillofacial development and affect the health of dentofacial system. Mouth breathers may present various types of growth patterns and malocclusion, depending on the exact etiology of mouth breathing. Furthermore, breathing through the oral cavity can negatively affect oral health, increasing the risk of caries and periodontal diseases. This review aims to provide a summary of recent publications with regard to the impact of mouth breathing on dentofacial development, describe their consistencies and differences, and briefly discuss potential reasons behind inconsistent findings

Syntheses and luminescent properties of a series of new lanthanide azelates

A series of new lanthanide azelates [Ln(aze)(Haze)(H2O)]·H2O {Ln = La (1a), Ce (1b), Pr (1c); H2aze = azelaic acid}, [Ln2(aze)3(phen)2]·H2O [Ln = Nd (2a), Er (2b); phen = 1,10-phenanthroline], [Sm(aze)(Haze)(phen)]·2H2O (3), [Gd(aze)(phen)2]·ClO4 (4) and (Hphen)[Tb2(aze)2(phen)4]·3ClO4 (5) were hydrothermally prepared and structurally characterized.1a-c are isostructural and show 3-D framework based on 1-D infinite [Ln-O-Ln]n chain. 2a-b exhibit sql layer, while 3 displays 1-D chain, where phen ligands locate at both sides of the chain. The Ln3+ ions of 4 and 5 are connected by aze2− into two different types of rare cationic 1-D chains. The luminescent investigations show that both 2a and 2b exhibit interesting NIR luminescence and 5 displays a good potentiality as a luminescent sensor targeted for Fe3+ ion. Of particular interest, lanthanide azelates have not been to date documented, while this work presents the only examples of lanthanide azelates exhibiting luminescent properties. The magnetic properties of some lanthanide azelates were also investigated.publishe

Association between adenotonsillar hypertrophy and dentofacial characteristics of children seeking for orthodontic treatment: A cross-sectional study

ObjectiveTo compare the dentofacial characteristics of children with and without adenoid and/or tonsillar hypertrophy.MethodsA consecutive sample of orthodontic patients aged 6-12 that took pre-treatment lateral cephalograms were included in this study. Those with history of previous orthodontic treatment, adenoidectomy or tonsillectomy, or craniofacial anomalies were excluded. The diagnosis of adenoid and tonsillar hypertrophy was based on Fujioka's and Baroni's methods, according to which the subjects were divided into four groups: the adenoid hypertrophy only (AHO) group; tonsillar hypertrophy only (THO) group; combined adenoid and tonsillar hypertrophy (AH+TH) group; and no adenoid or tonsillar hypertrophy (NH) group. Cephalograms were used for skeletal and dental measurement. Data were analyzed using one-way ANOVA, LSD post-hoc tests and Chi-square test.ResultsA total of 598 patients were included. Compared with the NH group, the THO group had significantly larger SNB angle (P&lt;0.001), as well as significantly smaller ANB angle (P&lt;0.001) and Wits value (P=0.001). The U1-L1 angle of AHO group was significantly smaller than that in the NH group (P=0.035). The proportion of adenoid hypertrophy in Class II patients was significantly higher than that in Class III patients (P=0.001). The proportion of tonsillar hypertrophy in Class III patients was significantly higher than that in Class I patients (P&lt;0.001) and Class II patients (P&lt;0.001).ConclusionOver 80% of children seeking orthodontic treatment had either adenoid or tonsillar hypertrophy. Children with adenoid hypertrophy tend to have skeletal Class II malocclusion, while those with tonsillar hypertrophy tend to have skeletal Class III malocclusion

A machine learning-based radiomics model for prediction of tumor mutation burden in gastric cancer

Purpose: To evaluate the potential of machine learning (ML)-based radiomics approach for predicting tumor mutation burden (TMB) in gastric cancer (GC).Methods: The contrast enhanced CT (CECT) images with corresponding clinical information of 256 GC patients were retrospectively collected. Patients were separated into training set (n = 180) and validation set (n = 76). A total of 3,390 radiomics features were extracted from three phases images of CECT. The least absolute shrinkage and selection operator (LASSO) model was used for feature screening. Seven machine learning (ML) algorithms were employed to find the optimal classifier. The predictive ability of radiomics model (RM) was evaluated with receiver operating characteristic. The correlation between RM and TMB values was evaluated using Spearman’s correlation coefficient. The explainability of RM was assessed by the Shapley Additive explanations (SHAP) method.Results: Logistic regression algorithm was chosen for model construction. The RM showed good predictive ability of TMB status with AUCs of 0.89 [95% confidence interval (CI): 0.85–0.94] and 0.86 (95% CI: 0.74–0.98) in the training and validation sets. The correlation analysis revealed a good correlation between RM and TMB levels (correlation coefficient: 0.62, p &lt; 0.001). The RM also showed favorable and stable predictive accuracy within the cutoff value range 6–16 mut/Mb in both sets.Conclusion: The ML-based RM offered a promising image biomarker for predicting TMB status in GC patients

Beneficial Effects and Safety of Corticosteroids Combined with Traditional Chinese Medicine for Pemphigus: A Systematic Review

Objective. To evaluate the beneficial effects and safety of corticosteroids combined with traditional Chinese medicine (TCM) for pemphigus. Methods. Seven electronic databases were searched to identify any potential randomized controlled trials (RCTs) or clinical controlled trials (CCTs) that compared corticosteroids with and without TCM for the treatment of pemphigus, published in any language. Remission of the mucocutaneous lesions, therapeutic duration, dosage of corticosteroids, and specific antibody titers were employed as the main outcome measures. The methodological quality of the included studies was assessed using the Cochrane Handbook for Systematic Review of Interventions and Rev Man 5.1.0 software. Results. Four RCTs with a total of 199 patients were included in the present review. Management with corticosteroids combined with TCM seemed to benefit pemphigus patients in terms of healing of lesions, prevention of complications and relapse, and reduced interferon-gamma (IFN-γ) level. The trials were not of high methodological quality. No study mentioned allocation concealment and blinding. Only one trial reported adverse events, and it indicated that the safety of corticosteroids combined with TCM was uncertain. Conclusion. There is some, albeit weak, evidence to show that combined treatment with corticosteroids with TCM could be of benefit for some patients with pemphigus. The efficacy and safety of this combined treatment should be evaluated further in better designed, fully powered, and confirmatory RCTs

Comprehensive analysis of prognosis of cuproptosis-related oxidative stress genes in multiple myeloma

Introduction: Multiple myeloma (MM) is a highly heterogeneous hematologic malignancy. The patients’ survival outcomes vary widely. Establishing a more accurate prognostic model is necessary to improve prognostic precision and guide clinical therapy.Methods: We developed an eight-gene model to assess the prognostic outcome of MM patients. Univariate Cox analysis, Least absolute shrinkage and selection operator (LASSO) regression, and multivariate Cox regression analyses were used to identify the significant genes and construct the model. Other independent databases were used to validate the model.Results: The results showed that the overall survival of patients in the high-risk group was signifificantly shorter compared with that of those in the low-risk group. The eight-gene model demonstrated high accuracy and reliability in predicting the prognosis of MM patients.Discussion: Our study provides a novel prognostic model for MM patients based on cuproptosis and oxidative stress. The eight-gene model can provide valid predictions for prognosis and guide personalized clinical treatment. Further studies are needed to validate the clinical utility of the model and explore potential therapeutic targets

Impact of pediatric obstructive sleep apnea on the development of Class II hyperdivergent patients receiving orthodontic treatment: A pilot study

Objectives: To conduct a pilot study to determine if the presence of obstructive sleep apnea (OSA) influences the orthodontic treatment outcome of Class II hyperdivergent patients receiving comprehensive orthodontic treatment. Materials and Methods: Patients between the ages of 12 and 14 who received orthodontic treatment at the Hospital of Stomatology, Wuhan University, China, were included in this study. Patients were divided into two groups: the OSA group and the control group, based on the outcome of pretreatment polysomnography findings and lateral cephalometric radiograph examination. Patients in the control group were matched with the OSA group for age, sex, ethnicity, weight, and height. Cephalometric measurements were used to record the skeletal and dental changes from before to after treatment. Data were analyzed using the t-test. Results: Twenty three OSA patients and 23 control patients were included. After comprehensive orthodontic treatment, the mandibular plane angle (SN-GoMe), articular angle (SArGo), sum of Jarabak angles (SUM) and the lower gonial angle (NGoMe) were found to increase significantly in the OSA group but remained unchanged or decreased slightly in the control group (P , .05). In the non-OSA group, the growth pattern became more horizontal. In contrast, in the OSA group the growth pattern became more vertical. Otherwise, similar treatment results were obtained for both groups in terms of sagittal change and occlusion. Conclusions: The presence of OSA in pediatric patients has a deleterious effect on the development of hyperdivergent malocclusions. Early diagnosis and management of pediatric OSA can affect the orthodontic treatment outcome of these patients. (Angle Orthod. 2018;88:560–566.