The CMS Phase-1 pixel detector upgrade

The CMS detector at the CERN LHC features a silicon pixel detector as its innermost subdetector. The original CMS pixel detector has been replaced with an upgraded pixel system (CMS Phase-1 pixel detector) in the extended year-end technical stop of the LHC in 2016/2017. The upgraded CMS pixel detector is designed to cope with the higher instantaneous luminosities that have been achieved by the LHC after the upgrades to the accelerator during the first long shutdown in 2013–2014. Compared to the original pixel detector, the upgraded detector has a better tracking performance and lower mass with four barrel layers and three endcap disks on each side to provide hit coverage up to an absolute value of pseudorapidity of 2.5. This paper describes the design and construction of the CMS Phase-1 pixel detector as well as its performance from commissioning to early operation in collision data-taking.Peer reviewe

Less Bone Loss With Maraviroc- Versus Tenofovir-Containing Antiretroviral Therapy in the AIDS Clinical Trials Group A5303 Study

Background. There is a need to prevent or minimize bone loss associated with antiretroviral treatment (ART) initiation. We compared maraviroc (MVC)- to tenofovir disoproxil fumarate (TDF)–containing ART

“Lingering effects” of discrimination: tracing persistence over time in local populations

The broad principle that historical injustice may call for corrective remedies in today’s world poses new and interesting challenges for applied demographers. I illustrate applications of demographic analysis to examine how former policies and practices produced effects that persist (or linger on) among members of a contemporary population. Such effects involve populations at different times and places and posit causal mechanisms that can be examined and evaluated. Applying standard demographic concepts and thinking to these issues can clarify and sharpen public understanding of whether past experiences still matter and precisely for whom, and whether proposed corrective remedies under the law are feasible. Copyright Springer Science+Business Media B.V. 2006Discrimination, Minority political participation, Racial segregation, Residential choice,