2,252 research outputs found
The Functions of Groups: A Psychometric Analysis of the Group Resources Inventory
What do groups do for their members? A functional model that assumes groups satisfy a number of basic survival, psychological, informational, interpersonal, and collective needs is offered. The authors examined the comprehensiveness of the model by asking members of various types of naturally occurring groups to describe the benefits they gained through membership. Analysis of those descriptions identified 16 key interpersonal functions of groups (such as social comparison, social exchange, social control, social esteem, social identity, and social learning), and individuals\u27 evaluations of the quality of their group were systematically related to their ratings of the group\u27s functionality. The authors discuss possible applications of these findings for improving groups but have concluded that additional work is needed to determine the applicability of the functions model to psychotherapeutic groups
Extension rates across the northern Shanxi Grabens, China, from Quaternary geology, seismicity and geodesy
Discrepancies between geological, seismic and geodetic rates of strain can indicate that rates of crustal deformation, and hence seismic hazard, are varying through time. Previous studies in the northern Shanxi Grabens, at the northeastern corner of the Ordos Plateau in northern China, have found extension rates of anywhere between 0 and 6 mm a−1 at an azimuth of between 95° and 180°. In this paper we determine extension rates across the northern Shanxi Grabens from offset geomorphological features and a variety of Quaternary dating techniques (including new IRSL and Ar-Ar ages), a Kostrov summation using a 700 yr catalogue of historical earthquakes, and recent campaign GPS measurements. We observe good agreement between Quaternary, seismic and geodetic rates of strain, and we find that the northern Shanxi Grabens are extending at around 1–2 mm a−1 at an azimuth of ≈151°. The azimuth of extension is particularly well constrained and can be reliably inferred from catalogues of small earthquakes. We do not find evidence for any substantial variations in extension rate through time, though there is a notable seismic moment rate deficit since 1750. This deficit could indicate complex fault interactions across large regions, aseismic accommodation of deformation, or that we are quite late in the earthquake cycle with the potential for larger earthquakes in the relatively near future
Do dance floor force reduction and static stiffness represent dynamic floor stiffness during dance landings?
Dance training on floors that are not \u27sprung\u27 are assumed to have direct implications for injury. Standards for dance floor manufacture in Europe and North America quantify floor force reduction by measuring the impact forces of drop masses. In addition, many studies of human mechanical adaptations to varied surfaces, have quantified test surfaces using measures of static stiffness. It is unclear whether these methods for the measurement of floor mechanical properties actually reflect dancer requirements or floor behaviour under dancer loading. The aim of this study was to compare the force reduction, static stiffness and dynamic stiffness of a range of dance floors. Dynamic stiffness was measured during dancers performing drop landings. Force reduction highly correlated (p= 0.086) with floors of moderate dynamic stiffness, but was less accurate for high and low stiffness floors. Static stiffness underestimated the dynamic stiffness of the floors. Measurement of floor force reduction using European sports surface standards may provide an accurate representation of dynamic floor stiffness when under load from dancers performing drop landings. The discrepancy between static and dynamic stiffness may be explained by the inertial characteristics of the floor and the rapid loading of the floors during dancer landings. The development of portable systems for measuring floor behaviour under human loads using modern motion capture technologies may be beneficial for improving the quantification of dance floor mechanical properties
Major Depressive Disorder and Factorial Dimensions Among Individuals With Recent-Onset Spinal Cord Injury
Objective: We examine the rates of major depressive disorder, single episode determined by the Inventory to Diagnose Depression (IDD) in a clinical sample of persons with recent-onset spinal cord injury (SCI; Յ52 weeks) participating in an inpatient SCI rehabilitation program. We also analyzed the factor structure of the IDD measure in an attempt to replicate the factor structure reported by Frank et al. (1992), and we examined item endorsement patterns. Design: A retrospective chart review was conducted. Participants were 354 individuals (93 women, 261 men) in an inpatient SCI rehabilitation program. Results: Fifteen percent of the sample met criteria for a major depressive disorder (MDD). A higher rate of depression was observed among women. A "dysphoria" factor accounted for 24% of the variance in the final four-factor model. The four-factor solution explained a total of 35.5% of the variance, with an "anhedonia" factor contributing 4.6%, a "sleep" factor contributing 3.5%, and an "appetite" factor contributing 3.5%, respectively. Items assessing symptoms of insomnia, weight loss, worrying about health, and decreased energy had the highest percentage of endorsement to meet Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria for clinical significance. Conclusions: The rate of single episodes of MDD determined by the IDD parallels the rate observed with the Patient Health Questionnaire-9 (PHQ-9). The factor structure of the IDD was similar to that reported by Frank et al. (1992). Information provided by the IDD about the presence and severity of MDD symptoms can inform interventions for persons with SCI. Keywords: spinal cord injury, depression, assessment, adjustment, factor analysis Impact and Implications • This study replicates and extends important features of the Frank et al. (1992) study of depression among persons with spinal cord injury (SCI) and the factor structure of the Inventory to Diagnose Depression (IDD). • The results provide important information about the rate of major depressive disorder (MDD) among persons with recent-onset SCI, and about gender differences in the rate of MDD and in the reporting of depressed mood. • Clinical practice and research should attend to the full range and profile of symptoms that are used to diagnose MDD in the inpatient SCI rehabilitation setting
Health care system collaboration to address chronic diseases: A nationwide snapshot from state public health practitioners
INTRODUCTION: Until recently, health care systems in the United States often lacked a unified approach to prevent and manage chronic disease. Recent efforts have been made to close this gap through various calls for increased collaboration between public health and health care systems to better coordinate provision of services and programs. Currently, the extent to which the public health workforce has responded is relatively unknown. The objective of this study is to explore health care system collaboration efforts and activities among a population-based sample of state public health practitioners. METHODS: During spring 2013, a national survey was administered to state-level chronic disease public health practitioners. Respondents were asked to indicate whether or not they collaborate with health care systems. Those who reported “yes” were asked to indicate all topic areas in which they collaborate and provide qualitative examples of their collaborative work. RESULTS: A total of 759 respondents (84%) reported collaboration. Common topics of collaboration activities were tobacco, cardiovascular health, and cancer screening. More client-oriented interventions than system-wide interventions were found in the qualitative examples provided. Respondents who collaborated were also more likely to use the Community Guide, use evidence-based decision making, and work in program areas that involved secondary, rather than primary, prevention. CONCLUSION: The study findings indicate a need for greater guidance on collaboration efforts that involve system-wide and cross-system interventions. Tools such as the Community Guide and evidence-based training courses may be useful in providing such guidance
Health-Related Quality of Life of Rural Clients Seeking Telepsychology Services
Sixty million US residents live in rural areas, but health policies and interventions developed from an urban mindset often fail to address the significant barriers to health experienced by these local communities. Telepsychology, or psychological services delivered by distance via technology, is an emerging treatment modality with special implications for underserved rural areas. This study found that a sample of rural residents seeking telepsychology services (n=94) had low health-related quality of life (HRQOL), often due to cooccurring physical and mental health diagnoses including high rates of depression. However, a brief telepsychology treatment delivered to rural clients (n=40) was associated with an improvement in mental health-related quality of life (d = 0.70, P<.001). These results indicate that despite the complex health needs of these underserved communities, telepsychology interventions may help offset the disparities in health service access in rural areas
The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins
BACKGROUND: The NCOA7 gene product is an estrogen receptor associated protein that is highly similar to the human OXR1 gene product, which functions in oxidation resistance. OXR genes are conserved among all sequenced eukaryotes from yeast to humans. In this study we examine if NCOA7 has an oxidation resistance function similar to that demonstrated for OXR1. We also examine NCOA7 expression in response to oxidative stress and its subcellular localization in human cells, comparing these properties with those of OXR1. RESULTS: We find that NCOA7, like OXR1 can suppress the oxidative mutator phenotype when expressed in an E. coli strain that exhibits an oxidation specific mutator phenotype. Moreover, NCOA7's oxidation resistance function requires expression of only its carboxyl-terminal domain and is similar in this regard to OXR1. We find that, in human cells, NCOA7 is constitutively expressed and is not induced by oxidative stress and appears to localize to the nucleus following estradiol stimulation. These properties of NCOA7 are in striking contrast to those of OXR1, which is induced by oxidative stress, localizes to mitochondria, and appears to be excluded, or largely absent from nuclei. CONCLUSION: NCOA7 most likely arose from duplication. Like its homologue, OXR1, it is capable of reducing the DNA damaging effects of reactive oxygen species when expressed in bacteria, indicating the protein has an activity that can contribute to oxidation resistance. Unlike OXR1, it appears to localize to nuclei and interacts with the estrogen receptor. This raises the possibility that NCOA7 encodes the nuclear counterpart of the mitochondrial OXR1 protein and in mammalian cells it may reduce the oxidative by-products of estrogen metabolite-mediated DNA damage
Economic evaluation of a community-based diagnostic pathway to stratify adults for non-alcoholic fatty liver disease: a Markov model informed by a feasibility study
Objectives: To assess the long-term cost-effectiveness of a risk stratification pathway, compared with standard care, for detecting non-alcoholic fatty liver disease (NAFLD) in primary care.
Setting: Primary care general practices in England.
Participants: Adults who have been identified in primary care to have a risk factor for developing NAFLD, that is, type 2 diabetes without a history of excessive alcohol use.
Intervention: A community-based pathway, which utilises transient elastography and hepatologists to stratify patients at risk of NAFLD, has been implemented and demonstrated to be feasible (NCT02037867). Earlier identification could mean earlier treatments, referral to specialist, and enrolment into surveillance programmes.
Design: The impact of earlier detection and treatment with the risk stratification pathway on progression to later stages of liver disease was examined using decision modelling with Markov chains to estimate lifetime health and economic effects of the two comparators.
Data sources: Data from a prospective cross-sectional feasibility study indicating risk stratification pathway and standard care diagnostic accuracies, were combined with a Markov model that comprised the following states: no/mild liver disease, significant liver disease, compensated cirrhosis; decompensated cirrhosis, hepatocellular carcinoma, liver transplant and death. The model data were chosen from up-to-date UK sources, published literature and an expert panel.
Outcome measure: An incremental cost-effectiveness ratio (ICER) indicating cost per quality adjusted life year (QALY) of the risk stratification pathway compared with standard care was estimated.
Results: The risk stratification pathway was more effective than standard care, and cost £2,138 per QALY gained. The ICER was most sensitive to estimates of the rate of fibrosis progression and the effect of treatment on reducing this, and ranged from -£1,895 to £7,032/QALY. The risk stratification pathway demonstrated an 85% probability of cost-effectiveness at the UK willingness-to-pay threshold of £20,000/QALY.
Conclusions: Implementation of a community-based risk stratification pathway is likely to be cost effective
(9R,9aS,12aR,13S)-9,13-Diphenyl-9,9a,12a,13-tetrahydro-9,13-methanotriphenyleno[2,3-c]furan-10,12,14-trione
X-ray crystallography was used to characterise the title compound for the first time, and the 1H NMR, 13C NMR and IR spectroscopic data from earlier reports were also updated.Publisher PDFPeer reviewe
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