US encouragement of a military coup in Venezuela is dangerous for both countries

Publicly condoning military action and using economic sanctions to provoke it will only exacerbate Venezuelan suffering and further damage the tattered reputation of the US on democracy and human-rights issues in the Western Hemisphere, writes Timothy M. Gill (University of North Carolina, Wilmington)

Diminishing Global Power, Downgrading Human Rights: Making Sense of American Foreign Policy under Donald Trump

President Donald Trump has generated much confusion concerning his foreign policy approach, and he has often displayed contradictory positions on an array of issues. Trump has, for example, praised authoritarian leaders in Eastern Europe, but condemned them in Latin America. The purpose of this paper is to make sense of Trump’s foreign policy approach, and its novelties and continuities, by putting his administration into comparative-historical focus alongside Bush II and Obama. I analyze their foreign policy approach by using Michael Mann’s IEMP model of power to draw out their distinctive qualities. Similar to Mann’s own analysis of Bush II, I show that Trump has prioritized the expansion of military power. Obama also utilized military force, but he sought to regain global support lost under Bush II by speaking the language of multilateralism, and opening up relations with former foes, particularly Cuba and Iran. Unlike Bush II and Obama, Trump has pursued some entirely divergent global policies, particularly involving his global trade war and bellicose rhetoric. Yet, similar to Bush, Trump has exacerbated the retreat from multilateral institutions by working to institutionalize them. Finally, I point out that the global ramifications of U.S. anti-globalism at this historical juncture differ from when Bush II occupied the White House. With the U.S. moving towards more isolationist policies, we can expect both China and Russia to accumulate global power relative to the U.S. and displace the U.S. as a hegemonic power in some areas of the world

Diminishing Global Power, Downgrading Human Rights: Making Sense of American Foreign Policy under Donald Trump

Scholars have remained puzzled about the direction that President Donald Trump might take the U.S. at the global level. Throughout his campaign, Trump often articulated contradictory ideas concerning his foreign policy approach. Trump evidenced warmth towards authoritarian leaders in Eastern Europe, but condemned them in Latin America. The purpose of this paper is to make sense of Trump’s foreign policy approach, and its novelties and continuities, by putting his administration into comparative-historical focus alongside Bush II and Obama. I analyze their foreign policy approach by using Michael Mann’s IEMP model of power to draw out their distinctive qualities. Similar to Mann’s own analysis of Bush II, I show that Trump has prioritized the expansion of military power. Obama also utilized military force, but he sought to regain global support lost under Bush II by speaking the language of multilateralism, and opening up relations with former foes, particularly Cuba and Iran. Unlike Bush II and Obama, Trump has pursued some entirely divergent global policies, particularly involving his global trade war and bellicose rhetoric. Yet, similar to Bush, Trump has exacerbated the retreat from multilateral institutions by working to institutionalize them. Finally, I point out that the global ramifications of U.S. anti-globalism at this historical juncture differ from when Bush II occupied the White House. With the U.S. moving towards more isolationist policies, we can expect both China and Russia to accumulate global power relative to the U.S. and displace the U.S. as a hegemonic power in some areas of the world

“Post-Western” diplomacy and the Venezuela crisis

Attempts by the Organization of American States to suspend Venezuela may not succeed. But as the Trump administration reshapes its relationship with multilateral institutions, there will be opportunities for “post-Western” diplomacy from within the region and beyond, write David Smilde and Timothy M. Gill

Two Decades of Imperial Failure: Theorizing U.S. Regime Change Efforts in Venezuela from Bush II to Trump

Former Venezuelan President Hugo Chávez ushered in the Pink Tide and the rise of the left in Latin America at the turn of the 21st century. Chávez initially won presidential elections in 1998 based on the promise of participatory democracy and tackling economic inequality, and thereafter by championing 21st Century Socialism. From the beginning, Chávez challenged U.S. global leadership by condemning its vision for the world and by cultivating an anti-imperial nexus of allies. This pattern has continued under current President Nicolás Maduro. In response, the U.S. has opposed the Venezuelan socialists throughout three successive presidential administrations: Bush II, Obama, and Trump. Taking influence from Michael Mann’s IEMP model of social power, we detail the ideological, economic, military, and political strategies these administrations have used to undermine the Venezuelan government and assist right-wing opposition parties and civil society groups in Venezuela. While Bush II and Obama primarily sought to depose Chávez by bolstering right-wing political parties and groups that aimed to unseat Chávez at the ballot box, Trump has recognized a parallel government open to an extra-legal change of government and openly called for coercive regime change through a military coup d’état

Developing a framework for the analysis of power through depotentia

Stakeholder participation in tourism policy-making is usually perceived as providing a means of empowerment. However participatory processes drawing upon stakeholders from traditionally empowered backgrounds may provide the means of removing empowerment from stakeholders. Such an outcome would be in contradiction to the claims that participatory processes improve both inclusivity and sustainability. In order to form an understanding of the sources through which empowerment may be removed, an analytical perspective has been developed deriving from Lukes�s views of power dating from 1974. This perspective considers the concept of depotentia as the removal of �power to� without speculating upon the underlying intent and also provides for the multidimensionality of power to be examined within a single study. The application of this analytical perspective has been tested upon findings of the government-commissioned report of the Countryside and Community Research Unit in 2005. The survey and report investigated the progress of Local Access Forums in England created in response to the Countryside and Rights of Way Act 2000. Consideration of the data from this perspective permits the classification of individual sources of depotentia which can each be addressed and potentially enable stakeholder groups to reverse loss of empowerment where it has occurred

Coupled evolution of nitrogen cycling and redoxcline dynamics on the Yangtze Block across the Ediacaran-Cambrian transition

The authors acknowledge funding support from the NSF FESD and Earth-Life Transitions programs (T.L.), the NASA Astrobiology Institute under Cooperative Agreement No. NNA15BB03A issued through the Science Mission Directorate (T.L.), the key project of the Natural Science Foundation of China (C.-F.C.) (No. 41730424), and the program of China Scholarships Council (Y.C.) (No. 201504910582). Nitrogen and carbon isotope analyses were funded by startup funds from Virginia Tech to B.C.G.The Ediacaran-Cambrian transition is characterized by the evolution of complex eukaryotes and rapid diversification of metazoans. However, linkages between environmental triggers and evolutionary patterns remain unclear. Here, we present high-resolution records of carbon and nitrogen isotopic data (δ13C, δ15N) for a drill core extending from the early Ediacaran Doushantuo Formation to the early Cambrian Jiumenchong Formation, located on the slope of the Yangtze Block. Our data show that sedimentary bulk nitrogen isotope values (δ15Nbulk) decrease progressively from the early Ediacaran to the early Cambrian, broadly concurrent with nitrogen isotope data from other sections throughout the Yangtze Block. During the early Ediacaran, however, δ15Nbulk values from our study are higher (maximum 11.2‰) compared to those from more restricted coeval sections, suggesting a higher degree of denitrification in our slope section. The early Ediacaran δ15Nbulk data from the Yangtze Block may thus provide indirect evidence for an upwelling system that led to a shallower redoxcline in slope environments of the Upper Yangtze region. Widespread light δ15Nbulk values from the early Cambrian (minimum −7.5‰) paired with excess silicate-bound nitrogen throughout much of the Yangtze Block are most parsimoniously interpreted as non-quantitative assimilation of ammonium (NH4+) with relatively high concentrations of NH4+ accumulating in the deep basin. Overall, the spatial and temporal trends in nitrogen cycling across the Yangtze Block suggest that fixed nitrogen was more bioavailable in the Ediacaran-Cambrian Yangtze Basin compared to previously studied Mesoproterozoic sections, although nitrogen speciation in the photic zone may have varied with time. Environmental factors such as oxygen levels and nitrogen bioavailability may have shaped the evolutionary trajectory of life on the Yangtze Block and potentially elsewhere across the Ediacaran-Cambrian transition.PostprintPeer reviewe

Life-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- and Alcohol-Related Deaths Using the Lives Saved Simulation Model.

Improvements in life expectancy among people living with human immunodeficiency virus (PLWH) receiving antiretroviral treatment in the United States and Canada might differ among key populations. Given the difference in substance use among key populations and the current opioid epidemic, drug- and alcohol-related deaths might be contributing to the disparities in life expectancy. We sought to estimate life expectancy at age 20 years in key populations (and their comparison groups) in 3 time periods (2004-2007, 2008-2011, and 2012-2015) and the potential increase in expected life expectancy with a simulated 20% reduction in drug- and alcohol-related deaths using the novel Lives Saved Simulation model. Among 92,289 PLWH, life expectancy increased in all key populations and comparison groups from 2004-2007 to 2012-2015. Disparities in survival of approximately a decade persisted among black versus white men who have sex with men and people with (vs. without) a history of injection drug use. A 20% reduction in drug- and alcohol-related mortality would have the greatest life-expectancy benefit for black men who have sex with men, white women, and people with a history of injection drug use. Our findings suggest that preventing drug- and alcohol-related deaths among PLWH could narrow disparities in life expectancy among some key populations, but other causes of death must be addressed to further narrow the disparities

Long-term collaboration reaps dividends for clinical research in chronic movement disorders.

Poster presented at the Clinical Trials Symposium, RD&E Exeter, 5/11/15

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium

Importance: There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC). Objective: To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes. Design, Setting, and Participants: This multicenter, prospective, case-control study was conducted by the National Collegiate Athletic Association (NCAA) and the US Department of Defense Concussion Assessment, Research, and Education (CARE) Consortium from February 20, 2015, to May 31, 2018, at 6 CARE Advanced Research Core sites. A total of 504 collegiate athletes with concussion, contact sport control athletes, and non-contact sport control athletes completed clinical testing and blood collection at preseason baseline, the acute postinjury period, 24 to 48 hours after injury, the point of reporting being asymptomatic, and 7 days after return to play. Data analysis was conducted from March 1 to November 30, 2019. Main Outcomes and Measures: Glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase-L1 (UCH-L1), neurofilament light chain, and tau were quantified using the Quanterix Simoa multiplex assay. Clinical outcome measures included the Sport Concussion Assessment Tool-Third Edition (SCAT-3) symptom evaluation, Standardized Assessment of Concussion, Balance Error Scoring System, and Brief Symptom Inventory 18. Results: A total of 264 athletes with concussion (mean [SD] age, 19.08 [1.24] years; 211 [79.9%] male), 138 contact sport controls (mean [SD] age, 19.03 [1.27] years; 107 [77.5%] male), and 102 non-contact sport controls (mean [SD] age, 19.39 [1.25] years; 82 [80.4%] male) were included in the study. Athletes with concussion had significant elevation in GFAP (mean difference, 0.430 pg/mL; 95% CI, 0.339-0.521 pg/mL; P < .001), UCH-L1 (mean difference, 0.449 pg/mL; 95% CI, 0.167-0.732 pg/mL; P < .001), and tau levels (mean difference, 0.221 pg/mL; 95% CI, 0.046-0.396 pg/mL; P = .004) at the acute postinjury time point compared with preseason baseline. Longitudinally, a significant interaction (group × visit) was found for GFAP (F7,1507.36 = 16.18, P < .001), UCH-L1 (F7,1153.09 = 5.71, P < .001), and tau (F7,1480.55 = 6.81, P < .001); the interaction for neurofilament light chain was not significant (F7,1506.90 = 1.33, P = .23). The area under the curve for the combination of GFAP and UCH-L1 in differentiating athletes with concussion from contact sport controls at the acute postinjury period was 0.71 (95% CI, 0.64-0.78; P < .001); the acute postinjury area under the curve for all 4 biomarkers combined was 0.72 (95% CI, 0.65-0.79; P < .001). Beyond SCAT-3 symptom score, GFAP at the acute postinjury time point was associated with the classification of athletes with concussion from contact controls (β = 12.298; 95% CI, 2.776-54.481; P = .001) and non-contact sport controls (β = 5.438; 95% CI, 1.676-17.645; P = .005). Athletes with concussion with loss of consciousness or posttraumatic amnesia had significantly higher levels of GFAP than athletes with concussion with neither loss of consciousness nor posttraumatic amnesia at the acute postinjury time point (mean difference, 0.583 pg/mL; 95% CI, 0.369-0.797 pg/mL; P < .001). Conclusions and Relevance: The results suggest that blood biomarkers can be used as research tools to inform the underlying pathophysiological mechanism of concussion and provide additional support for future studies to optimize and validate biomarkers for potential clinical use in SRC