Contextual Control of Perceptual Behavior

This paper offers an experimental analysis of changes in perception. In doing so, the relative flexibility of a person's perception of color as a product of interacting with other colors will be demonstrated through a matching procedure in a training and testing methodology. The analysis focuses on how setting factors (i.e. color stimuli immediately preceding a test color stimulus) come to affect a person's behavior with respect to the test stimulus. We argue that what is present for a participant in interaction with a stimulus is a history of past interactions with other stimuli. Data obtained from the pilot investigation demonstrated extensive differentiation in responding during testing conditions as compared to training in four of five participants. Questions regarding the way in which pilot participants followed the instructions were raised and as a result a subsequent investigation was conducted to incorporate more explicit instructions and controls for the appearance of colors. Results from this investigation show response differentiation to a lesser extent then in the pilot, however, data obtained more closely resemble the subtle phenomena of perception

Tidally Induced Oscillations and Orbital Decay in Compact Triple-Star Systems

We investigate the nature of tidal effects in compact triple-star systems. The hierarchical structure of a triple system produces tidal forcing at high frequencies unobtainable in binary systems, allowing for the tidal excitation of high frequency p-modes in the stellar components. The tidal forcing exists even for circular, aligned, and synchronized systems. We calculate the magnitude and frequencies of three-body tidal forcing on the central primary star for circular and coplanar orbits, and we estimate the amplitude of the tidally excited oscillation modes. We also calculate the secular orbital changes induced by the tidally excited modes, and show that they can cause significant orbital decay. During certain phases of stellar evolution, the tidal dissipation may be greatly enhanced by resonance locking. We then compare our theory to observations of HD 181068, which is a hierarchical triply eclipsing star system in the Kepler field of view. The observed oscillation frequencies in HD 181068 can be naturally explained by three-body tidal effects. We then compare the observed oscillation amplitudes and phases in HD 181068 to our predictions, finding mostly good agreement. Finally, we discuss the past and future evolution of compact triple systems like HD 181068.Comment: 19 pages, 8 figures, published in MNRA

INDOT Intelligent Road Design and Construction Using 3D Models

This presentation provides an update on INDOT’s e-construction and Intelligent Design and Construction initiatives. This will include a discussion of INDOT’s efforts over the past year to move toward 3D CAD models for roadway design, advancements in digital/electronic construction inspection including further development and refining of inspection checklists, continued development and testing of a mobile inspection application, and demonstration projects for e-ticketing of HMA materials delivery

Does The Hype Exceed The Reality For ERP Applications And Small Manufacturing Companies: A Case Study

This case study describes the implementation of an ERP in a new arena – small manufacturing companies – and explores possible differences compared with successful implementations of ERP’s in larger manufacturing companies. The company that was studied is a small manufacturing company in Maine (less than $10 million in annual sales) that began implementing a small business ERP 12 months ago. Information was collected through interviews and the completion of a questionnaire based on the Stratman-Roth ERP Competence Scales (2002). Results suggest that while this company’s ERP implementation has been more positive than negative, a small company’s limited financial resources and lack of internal experience and expertise in large IT system projects add to the already complex challenges surrounding an ERP implementation

1862-12-18 Timothy Fuller recommends W.A. Huntress and Charles Merrill for commissions

https://digitalmaine.com/cw_me_1st_heavy_corr/1032/thumbnail.jp

LOWER BODY PEAK FORCE BUT NOT POWER IS AN IMPORTANT DISCRIMINATOR OF ELITE SENIOR RUGBY LEAGUE PLAYERS

This investigation determined differences in lower body strength and power between elite junior (17-20 years) and elite senior (open-aged) rugby league athletes. Twenty junior and 25 senior athletes performed an isometric mid-thigh pull, countermovement jump, repeated jump, and broad jump tests during a National Rugby League pre-season. The effects of age (junior vs. senior) and position (adjustables vs. hit-up forwards vs. outside backs) on test results were investigated using a two-way analysis of variance. Cohen’s d effect sizes (ES) and 95% confidence intervals were calculated for pairwise comparisons. Isometric mid-thigh pull absolute peak force was greater for senior players compared to junior players (ES=0.88, p<.05). Countermovement jump absolute peak power was greater for outside backs (ES=1.12) and hit-up forwards (ES=1.23) compared to adjustables (p<.05), greater for senior outside backs compared to junior outside backs (ES=1.53, p<.05), and greater for junior hit-up forwards compared to senior hit-up forwards (ES=1.00, p<.05). This research demonstrated the differences in strength and power of rugby league athletes between playing age and position. Improving lower body strength should be prioritised for athletic development of junior rugby league athletes, with consideration given to requirements across different playing positions

Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition

Inhibition of glycogen synthase kinase 3β (GSK3β) as a consequence of its phosphorylation by protein kinase B/Akt (PKB/Akt) has been implicated in cardiac myocyte hypertrophy in response to endothelin-1 or phenylephrine. We examined the regulation of GSK3α (which we show to constitute a significant proportion of the myocyte GSK3 pool) and GSK3β in cardiac myocytes. Although endothelin increases phosphorylation of GSK3 and decreases its activity, the response is less than that induced by insulin (which does not promote cardiac myocyte hypertrophy). GSK3 phosphorylation induced by endothelin requires signalling through the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade and not the PKB/Akt pathway, whereas the reverse is true for insulin. Cardiac myocyte hypertrophy involves changes in morphology, and in gene and protein expression. The potent GSK3 inhibitor 1-azakenpaullone increases myocyte area as a consequence of increased cell length whereas phenylephrine increases both length and width. Azakenpaullone or insulin promotes AP1 transcription factor binding to an AP1 consensus oligonucleotide, but this was significantly less than that induced by endothelin and derived principally from increased binding of JunB protein, the expression of which was increased. Azakenpaullone promotes significant changes in gene expression (assessed by Affymetrix microarrays), but the overall response is less than with endothelin and there is little overlap between the genes identified. Thus, although GSK3 may contribute to cardiac myocyte hypertrophy in some respects (and presumably plays an important role in myocyte metabolism), it does not appear to contribute as significantly to the response induced by endothelin as has been maintained

Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes

Background: Endothelin-1 stimulates Gq protein-coupled receptors to promote proliferation in dividing cells or hypertrophy in terminally differentiated cardiomyocytes. In cardiomyocytes, endothelin-1 rapidly (within minutes) stimulates protein kinase signaling, including extracellular-signal regulated kinases 1/2 (ERK1/2; though not ERK5), with phenotypic/physiological changes developing from approximately 12 h. Hypertrophy is associated with changes in mRNA/protein expression, presumably consequent to protein kinase signaling, but the connections between early, transient signaling events and developed hypertrophy are unknown. Results: Using microarrays, we defined the early transcriptional responses of neonatal rat cardiomyocytes to endothelin-1 over 4 h, differentiating between immediate early gene (IEG) and second phase RNAs with cycloheximide. IEGs exhibited differential temporal and transient regulation, with expression of second phase RNAs within 1 h. Of transcripts upregulated at 30 minutes encoding established proteins, 28 were inhibited >50% by U0126 (which inhibits ERK1/2/5 signaling), with 9 inhibited 25-50%. Expression of only four transcripts was not inhibited. At 1 h, most RNAs (approximately 67%) were equally changed in total and polysomal RNA with approximately 17% of transcripts increased to a greater extent in polysomes. Thus, changes in expression of most protein-coding RNAs should be reflected in protein synthesis. However, approximately 16% of transcripts were essentially excluded from the polysomes, including some protein-coding mRNAs, presumably inefficiently translated. Conclusion: The phasic, temporal regulation of early transcriptional responses induced by endothelin-1 in cardiomyocytes indicates that, even in terminally differentiated cells, signals are propagated beyond the primary signaling pathways through transcriptional networks leading to phenotypic changes (that is, hypertrophy). Furthermore, ERK1/2 signaling plays a major role in this response

Evidence of Multiple r-Process Sites in the Early Galaxy: New Observations of CS 22892-052

First results are reported of a new abundance study of neutron-capture elements in the ultra-metal-poor (UMP; [Fe/H] = -3.1) halo field giant star CS 22892-052. Using new high resolution, high signal-to-noise spectra, abundances of more than 30 neutron-capture elements (Z>30) have been determined. Six elements in the 40<Z<56 domain (Nb, Ru, Rh, Pd, Ag and Cd) have been detected for the first time in a UMP star. Abundances are also derived for three of the heaviest stable elements (Os, Ir, and Pb). A second transition of thorium, Th{4086}, confirms the abundance deduced from the standard Th{4019} line, and an upper limit to the abundance of uranium is established from the absence of the U{3859} line. As found in previous studies, the abundances of the heavier (Z>=56) stable neutron-capture elements in CS 22892-052 match well the scaled solar system r-process abundance distribution. From the observed Th abundance, an average age of ~= 16 +/- 4 Gyr is derived for cs22892-052, consistent with the lower age limit of ~= 11 Gyr derived from the upper limit on the U abundance. The concordance of scaled solar r-process and CS 22892-052 abundances breaks down for the lighter neutron-capture elements, supporting previous suggestions that different r-process production sites are responsible for lighter and heavier neutron-capture elements.Comment: To be published in the Astrophysical Journal Letter