Halothane hepatitis with renal failure treated with hemodialysis and exchange transfusion

A 38-year-old white female, hepatitis B antigen negative, developed fluminating hepatic failure associated with oliguria and severe azotemia after two halothane anesthesia and without exposure to other hepatotoxic drugs or blood transfusions. She was treated with multiple hemodialysis and exchange blood transfusion. The combined treatment corrected the uremic abnormalities and improved her level of consciousness. The liver and kidney function gradually improved, and she made a complete recovery, the first recorded with hepatic and renal failure under these post-anesthetic conditions. Further evaluation of this combined treatment used for this patient is warranted. © 1974 The Japan Surgical Society

An updated survey of globular clusters in M31. II Newly discovered bright and remote clusters

We present the first results of a large spectroscopic survey of candidate globular clusters located in the extreme outskirts of the nearby M31 galaxy. We obtained low resolution spectra of 48 targets selected from the XSC of 2MASS, as in Galleti et al. (2005). The observed candidates have been robustly classified according to their radial velocity and by verifying their extended/point-source nature from ground-based optical images. Among the 48 observed candidates clusters we found 5 genuine remote globular clusters. One of them has been already identified independently by Mackey et al. (2007), their GC1; the other four are completely new discoveries: B516, B517, B518, B519. The newly discovered clusters lie at projected distance 40 kpc<~R_p<~100 kpc from the center of M31, and have absolute integrated magnitude -9.5<M_V<-7.5. For all the observed clusters we have measured the strongest Lick indices and we have obtained spectroscopic metallicity estimates. Mackey-GC1, Martin-GC1, B517 and B518 have spectra typical of old and metal poor globular clusters ([Fe/H]<~ -1.3); B519 appears old but quite metal-rich ([Fe/H]~-0.5); B516 presents very strong Balmer absorption lines: if this is indeed a cluster it should have a relatively young age (likely <2 Gyr). The present analysis nearly doubles the number of M31 globulars at R_p> 40 kpc. At odds with the Milky Way, M31 appears to have a significant population of very bright globular clusters in its extreme outskirts.Comment: 16 pages including 6 pages published only in the electronic edition of the Journal. Accepted for publication in A&

Global metallicity of globular cluster stars from colour-magnitude diagrams

We have developed an homogeneous evolutionary scenario for H- and He-burning low-mass stars by computing updated stellar models for a wide metallicity and age range (0.0002$\le Z \le$0.004 and 9$\le t(Gyr) \le$15, respectively) suitable to study globular clusters. This theoretical scenario allows us to provide self-consistent predictions about the dependence of selected observational features of the colour-magnitude diagram, such as the brightness of the Turn Off (TO), Zero Age Horizontal Branch (ZAHB) and Red Giant Branch bump (BUMP), on the cluster metallicity and age. Taking into account these predictions, we introduce a new observable based on the visual magnitude difference between the TO and the ZAHB, and the TO and the RGB-bump, given by $A=\Delta M_V$(TO-BUMP)$-0.566\Delta M_V$(TO-ZAHB). We show that the parameter $A$ does not depend at all on the cluster age, whereas it does strongly depend on the cluster global metallicity. The calibration of the parameter $A$ as a function of $Z$ is then provided, as based on our evolutionary models. We tested the reliability of this result by also considering stellar models computed by other authors,employing different input physics. Eventually, we present clear evidence that the variation of $\Delta M_V$(TO-BUMP) with $\Delta M_V$(TO-ZAHB) does supply a powerful probe of the global metal abundance, at least when homogeneous theoretical frameworks are adopted. We provide an estimate of the global metallicity of 36 globular clusters in the Milky Way, based on our {\it A-Z} calibration, and a large observational database of Galactic GCs. By considering the empirical [Fe/H] scales by both Zinn & West (1984) and Carretta & Gratton (1997), we are also able to provide an estimate of the GC $\alpha-$element enhancement.Comment: 10 pages, 10 figures, in press on MNRA

Ursinus College Alumni Journal, March 1964

Standing room only • New student facilities building • Campaign receipts reach $285,765 at mid-March • Matching gifts • Mid-year report of 1964 Loyalty Fund campaign • Income while you live . . . benefaction when you die • Cutting campus • John Fitzgerald Kennedy • Eccentricities of our political life • A bitter dramatic example • Crisis of conscience in Dallas • Student reaction to November 22-25 • Two recipients for 1964 alumni award • The class of 1911 • The alumni album: C. Richard Snyder, \u2729; William D. Reimert, \u2724; Wainright E. H. Diehl, \u2751; Marguerite Goldthwaite Godshall, \u2732; Franklin E. Morris, \u2741; J. William Ditter, Jr., \u2743; Robert Poole, III, \u2750; Bain and Edwards\u27 sons: football foes • Nominees for alumni association offices • Class notes • Weddings • Births • Necrology • Regionalshttps://digitalcommons.ursinus.edu/alumnijournal/1079/thumbnail.jp

Proposing new variables for the identification of strategic groups in franchising

The identification of strategic groups in the Spanish franchising area is the main aim of this study. The authors have added some new strategic variables (not used before) to the study and have classified franchisors between sectors and distribution strategy. The results reveal the existence of four perfectly differentiated strategic groups (types of franchisors). One of the major implications of this study is that the variables that build a strategic group vary depending on the respective sector the network operates in and its distribution strategy. This fact indicates that including sector and distribution strategy is absolutely necessary to achieve good classifications of franchisor type

Parasitoid Increases Survival of Its Pupae by Inducing Hosts to Fight Predators

Many true parasites and parasitoids modify the behaviour of their host, and these changes are thought to be to the benefit of the parasites. However, field tests of this hypothesis are scarce, and it is often unclear whether the host or the parasite profits from the behavioural changes, or even if parasitism is a cause or consequence of the behaviour. We show that braconid parasitoids (Glyptapanteles sp.) induce their caterpillar host (Thyrinteina leucocerae) to behave as a bodyguard of the parasitoid pupae. After parasitoid larvae exit from the host to pupate, the host stops feeding, remains close to the pupae, knocks off predators with violent head-swings, and dies before reaching adulthood. Unparasitized caterpillars do not show these behaviours. In the field, the presence of bodyguard hosts resulted in a two-fold reduction in mortality of parasitoid pupae. Hence, the behaviour appears to be parasitoid-induced and confers benefits exclusively to the parasitoid

Evidence That Descending Cortical Axons Are Essential for Thalamocortical Axons to Cross the Pallial-Subpallial Boundary in the Embryonic Forebrain

Developing thalamocortical axons traverse the subpallium to reach the cortex located in the pallium. We tested the hypothesis that descending corticofugal axons are important for guiding thalamocortical axons across the pallial-subpallial boundary, using conditional mutagenesis to assess the effects of blocking corticofugal axonal development without disrupting thalamus, subpallium or the pallial-subpallial boundary. We found that thalamic axons still traversed the subpallium in topographic order but did not cross the pallial-subpallial boundary. Co-culture experiments indicated that the inability of thalamic axons to cross the boundary was not explained by mutant cortex developing a long-range chemorepulsive action on thalamic axons. On the contrary, cortex from conditional mutants retained its thalamic axonal growth-promoting activity and continued to express Nrg-1, which is responsible for this stimulatory effect. When mutant cortex was replaced with control cortex, corticofugal efferents were restored and thalamic axons from conditional mutants associated with them and crossed the pallial-subpallial boundary. Our study provides the most compelling evidence to date that cortical efferents are required to guide thalamocortical axons across the pallial-subpallial boundary, which is otherwise hostile to thalamic axons. These results support the hypothesis that thalamic axons grow from subpallium to cortex guided by cortical efferents, with stimulation from diffusible cortical growth-promoting factors

A Parasitoid Wasp Induces Overwintering Behaviour in Its Spider Host

Parasites and parasitoids control behaviors of their hosts. However, the origin of the behavior evoked by the parasitic organism has been rarely identified. It is also not known whether the manipulation is universal or host-specific. Polysphinctine wasps, koinobiont ectoparasitoids of several spider species that manipulate host web-spinning activity for their own protection during pupation, provide an ideal system to reveal the origin of the evoked behavior. Larva of Zatypota percontatoria performed species-specific manipulation of theridiid spiders, Neottiura bimaculata and Theridion varians, shortly before pupation. Parasitized N. bimaculata produced a dense web, whereas parasitized T. varians built a cupola-like structure. The larva pupated inside of either the dense web or the cupola-like structure. We discovered that unparasitized N. bimaculata produce an analogous dense web around their eggsacs and for themselves during winter, while T. varians construct an analogous ‘cupola’ only for overwintering. We induced analogous manipulation in unparasitized hosts by altering ambient conditions. We discovered that the behavior evoked by larvae in two hosts was functionally similar. The larva evoked protective behaviors that occur in unparasitized hosts only during specific life-history periods