Detrital-zircon geochronology and provenance of the Ocloyic synorogenic clastic wedge, and Ordovician accretion of the Argentine Precordillera terrane

The Precordillera terrane in northwestern Argentina is interpreted to be anexotic (Laurentian) continental fragment that was accreted to western Gondwanaduring the Ordovician. One prominent manifestation of the subductionand collision process is a Middle?Upper Ordovician clastic wedge, which overliesa passive-margin carbonate-platform succession in the Precordillera. U/Pbages of detrital zircons from sandstones within the clastic wedge, as well as zirconsfrom clasts within conglomerates, provide documentation for the compositionof the sediment provenance. The ages of detrital zircons are consistentvertically through the succession, as well as laterally along and across strike ofthe Precordillera, indicating a single, persistent sediment source throughoutdeposition of the clastic wedge. The dominant mode (~1350?1000 Ma) of thedetrital-zircon ages corresponds to the ages of basement rocks in the WesternSierras Pampeanas along the eastern side of the Precordillera. A secondarymode (1500?1350 Ma) corresponds in age to the Granite-Rhyolite province ofLaurentia, an age range which is not known in ages of basement rocks of theWestern Sierras Pampeanas; however, detritus from Granite-Rhyolite-age rocksin the basement of the Precordillera was available through recycling of synriftand passive-margin cover strata. Igneous clasts in the conglomerates haveages (647?614 Ma) that correspond to the ages of minor synrift igneous rocks inthe nearby basement massifs; the same ages are represented in a minor mode(~750?570 Ma) of detrital-zircon ages. A quartzite clast in a conglomerate, aswell as parts of the population of detrital zircons, indicates the importanceof a source in the metasedimentary cover of the leading edge of the Precordillera.The Famatina continental-margin magmatic arc reflects pre-collisionsubduction of Precordillera lithosphere beneath the western Gondwana margin;however, no detrital zircons have ages that correspond to Famatina arcmagmatism, indicating that sedimentary detritus from the arc may have beentrapped in a forearc basin and did not reach the foreland. The indicators ofsedimentary provenance for the foreland deposits are consistent with subductionof the Precordillera beneath western Gondwana, imbrication of basementrocks from either the Precordillera or Gondwana into an accretionary complex,and recycling of deformed Precordillera cover rocks.Fil: Thomas, William A.. Geological Survey of Alabama; Estados UnidosFil: Astini, Ricardo Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Ciencias de la Tierra. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones en Ciencias de la Tierra; ArgentinaFil: Mueller, Paul A.. Florida State University; Estados UnidosFil: McClelland, William C.. University of Iowa; Estados Unido

Cell cycle regulation of a Xenopus Wee1-like kinase

Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner. The addition of exogenous Wee1 protein to Xenopus cell cycle extracts results in a dose-dependent delay of mitotic initiation that is accompanied by enhanced tyrosine phosphorylation of Cdc2. The activity of the Wee1 protein is highly regulated during the cell cycle: the interphase, underphosphorylated form of Wee1 (68 kDa) phosphorylates Cdc2 very efficiently, whereas the mitotic, hyperphosphorylated version (75 kDa) is weakly active as a Cdc2-specific tyrosine kinase. The down-modulation of Wee1 at mitosis is directly attributable to phosphorylation, since dephosphorylation with protein phosphatase 2A restores its kinase activity. During interphase, the activity of this Wee1 homolog does not vary in response to the presence of unreplicated DNA. The mitosis-specific phosphorylation of Wee1 is due to at least two distinct kinases: the Cdc2 protein and another activity (kinase X) that may correspond to an MPM-2 epitope kinase. These studies indicate that the down-regulation of Wee1-like kinase activity at mitosis is a multistep process that occurs after other biochemical reactions have signaled the successful completion of S phase

Aircraft and ground vehicle friction correlation test results obtained under winter runway conditions during joint FAA/NASA Runway Friction Program

Aircraft and ground vehicle friction data collected during the Joint FAA/NASA Runway Friction Program under winter runway conditions are discussed and test results are summarized. The relationship between the different ground vehicle friction measurements obtained on compacted snow- and ice-covered conditions is defined together with the correlation to aircraft tire friction performance under similar runway conditions

Evaluation of two transport aircraft and several ground test vehicle friction measurements obtained for various runway surface types and conditions. A summary of test results from joint FAA/NASA Runway Friction Program

Tests with specially instrumented NASA Boeing 737 and 727 aircraft together with several different ground friction measuring devices were conducted for a variety of runway surface types and conditions. These tests are part of joint FAA/NASA Aircraft/Ground Vehicle Runway Friction Program aimed at obtaining a better understanding of aircraft ground handling performance under adverse weather conditions and defining relationships between aircraft and ground vehicle tire friction measurements. Aircraft braking performance on dry, wet, snow and ice-covered runway conditions is discussed as well as ground vehicle friction data obtained under similar runway conditions. For a given contaminated runway surface condition, the correlation between ground vehicles and aircraft friction data is identified. The influence of major test parameters on friction measurements such as speed, test tire characteristics, type and amount of surface contaminant, and ambient temperature are discussed. The effect of surface type on wet friction levels is also evaluated from comparative data collected on grooved and ungrooved concrete and asphalt surfaces

The development of a novel, CoA-dependent, organic acid modification system as a link to a biosynthetic pathway for the nylon 6 monomer, 6-aminocaproic acid

The inherently unsustainable production chain of the nylon 6 monomer, 6-aminocaproic acid (6-ACA), has motivated a number of investigations into developing sustainable alternatives. Previous research at UCL developed a biosynthetic pathway from cyclohexanol to 6-ACA. However, the requirement for petroleum-derived cyclohexanol, limited the pathway’s sustainability. Therefore, this investigation aimed to develop a biosynthetic pathway for renewable cyclohexanol production, from an intermediate of central metabolism. The pathway developed here, utilises eight enzymes for the production of cyclohexanol, through the CoA-dependent biotransformation of either shikimate or 3-phosphshikimate. Cyclohexanol production was not fully realised, however, exploring new biosynthetic routes for cyclohexanol production revealed several new enzymes and systems that were characterised and constructed. Four enzymes (MycA1-4), identified in Streptomyces rishiriensis, were recombinantly expressed and assayed. The acyl-CoA reductase, MycA2, showed activity with cyclohex-1-enecarbonyl CoA and 3-hydroxycyclohex-1-enecarbonyl CoA. MycA4, a proposed hydratase/phosphatase, was inactive, attributed to either protein misfolding, or an alternative catalytic mechanism. Combined activity of ChCoADH (Synthrophus aciditrophicus), an acyl-CoA dehydrogenase and BadK (Rhodopseudomonas pseudopalustris), an enoyl-CoA hydratase, facilitated the conversion of cyclohexanecarbonyl CoA into 2-hydroxycyclohexanecarbonyl CoA. Activity analysis of four Hotdog-fold thioesterases, revealed RpaL (Rhodopseudomonas palustris) to have a promiscuous substrate acceptance, and to catalyse the required hydrolysis of 2-hydroxycyclohexanecarbonyl CoA to 2-hydroxycyclohexanocarboxylate. A limited availability of CoA esters prevented the experimental analysis of many enzymatic steps. Resultantly, the CoA ligase, AliA (Rhodopseudomonas pseudopalustris), was screened and found to produce aromatic and alicyclic 4 CoA esters. Finally, a three-module system for the rational production of modified organic acids, via CoA ester intermediates, was tested. By coupling (1) broad AliA activity, (2) CoA modification (ChCoADH/ BadK) and (3) promiscuous RpaL activity, theoretically, a number of modified organic acids could be derived. Initial testing showed this system capable of producing cyclohex-1-enecarboxylate and 2-hydroxycyclohexanecarboxylate from cyclohexanecarboxylate. However, further exploitation of the CoA-utilising enzymes in endogenous metabolism, will undoubtedly expand this systems potential for rationally producing modified organic acids of commercial interest

Comments on the 'China model'

This paper reviews the articles by Pan and by Zhu on the China Model. The review of Pan is critical, that of Zhu sympathetic. Pan is criticised for taking an unquestioning attitude towards state supporting ideologies and failing to adequately account for the effects of changes in family structure and class structure in China over the past 50 years. The reviewer broadly agrees with Zhu's comments about a future steady state economy. The article provides statistical data from the recent economic and demographic histories of China and Japan to back up the general conclusions drawn by Zhu

Regional analysis of trend and step changes observed in hydroclimatic variables around the Colorado River Basin

Recent research has suggested that changes in temperature and precipitation events due to climate change have had a significant impact on the availability and timing of streamflow. In this study, monthly temperature and precipitation data collected over 29 climate divisions covering the entire Colorado River basin and monthly natural flow data from 29 U.S. Geological Survey (USGS) gauge locations along the Colorado River are investigated for trend or step changes using parametric and nonparametric statistical tests. Temperature increases are persistent (at least 10 climate divisions over 6 months in trend analysis) throughout the year over the Colorado River basin, whereas precipitation only notably increased over 17 climate divisions (during trend analysis) during February and remained relatively unchanged otherwise. These results correspond with changes in naturalized streamflow throughout the year. Streamflow increases are recorded between November and February but exhibit a decreasing trend over the traditional peak runoff season (April through July). Under trend analysis, 18 flow stations exhibited increasing trends in January and 19 flow stations exhibited decreasing trends in June. It is likely that increasing temperature trends have affected the character of precipitation in the Colorado River basin, causing a change in the timing of runoff events

Advances in Shock Compression of Mantle Materials and Implications

Hugoniots of lower mantle mineral compositions are sensitive to the conditions where they cross phase boundaries including both polymorphic phase transitions and partial to complete melting. For SiO_2, the Hugoniot of fused silica passes from stishovite to partial melt (73 GPa, 4600 K) whereas the Hugoniot of crystal quartz passes from CaCi_2 structure to partial melt (116 GPa, 4900 K). For Mg_2SiO_4, the forsterite Hugoniot passes from the periclase +MgSiO_3 (perovskite) assemblage to melt before 152 GPa and 4300 K, whereas the wadsleyite Hugoniot transforms first to periclase +MgSiO_3 (post-perovskite) and then melts at 151 GPa and 4160 K. Shock states achieved from crystal enstatite are molten above 160 GPa. High-pressure Grüneisen parameters for molten states of MgSiO_3 and Mg_2SiO_4 increase markedly with compression, going from 0.5 to 1.6 over the 0 to 135 GPa range. This gives rise to a very large (>2000 K) isentropic rise in temperature with depth in thermal models of a primordial deep magma ocean within the Earth. These magma ocean isentropes lead to models that have crystallization initiating at mid-lower mantle depths. Such models are consistent with the suggestion that the present ultra-low velocity zones, at the base of the lowermost mantle, represent a dynamically stable, partially molten remnant of the primordial magma ocean. The new shock melting data for silicates support a model of the primordial magma ocean that is concordant with the Berkeley-Caltech iron core model [1] for the temperature at the center of the Earth

Shock temperatures of preheated MgO

Shock temperature measurements via optical pyrometry are being conducted on single-crystal MgO preheated before compression to 1905–1924 K. Planar shocks were generated by impacting hot Mo(driver plate)-MgO targets with Mo or Ta flyers launched by the Caltech two-stage light-gas gun up to 6.6 km/s. Quasi-brightness temperature was measured with 2–3% uncertainty by a 6-channel optical pyrometer with 3 ns time resolution, over 500–900 nm spectral range. A high-power, coiled irradiance standard lamp was adopted for spectral radiance calibration accurate to 5%. In our experiments, shock pressure in MgO ranged from 102 to 203 GPa and the corresponding temperature varied from 3.78 to 6.53 kK. For the same particle velocity, preheated MgO Hugoniot has about 3% lower shock velocity than the room temperature Hugoniot. Although model shock temperatures calculated for the solid phase exceeded our measurements by ~5 times the uncertainty, there was no clear evidence of MgO melting, up to the highest compression achieved