Eye enucleation and exenteration in -cattle: a retrospective study of 38 cases (2013-2020).

INTRODUCTION The study aimed to describe clinical indications for eye enucleation and exenteration, the occurrence of complications and long-term outcome in cattle, and examine owners' attitude towards enucleation and exenteration and their satisfaction with the surgical outcome. Medical records from the two veterinary teaching hospitals in Switzerland were reviewed to identify cattle that underwent unilateral enucleation or exenteration between January 2013 and December 2020. Data extracted included medical history, ocular examination, clinical diagnosis, surgical procedure including anesthesia, suture material and pattern used, complications, and treatment thereof. Long-term follow-up was evaluated via national animal database inquiries to determine survival time and via owners' interviews with the use of a standardized questionnaire that included questions regarding the occurrence of complications and reason for culling, production performances and perceived quality of life after surgery, concerns, factors affecting the decision to proceed with surgery, and general satisfaction with the outcome. Descriptive statistics, Fisher's exact tests and unpaired t-test were used to summarize the data and assess association between variables. Association was considered significant if p < 0,05. Thirty-eight cases were identified, with a median age of 5 years. More than half of the cases (55,3 %) were diagnosed with non-neoplastic ocular lesions represented by severe trauma with loss of globe content, globe rupture with history of infectious keratoconjunctivitis or hypopyon, or congenital malformations. The remaining cases were diagnosed with neoplastic lesions, including ocular squamous cell carcinoma (OSCC), melanoma, or sarcoma. Complications following surgery were reported in 29 % of cases and included postoperative infection and recurrence of OSCC. There was no significant association between ocular diagnosis and the occurrence of postoperative complications or survival time. Surgery did not seem to influence the animals' postoperative production performance or the perceived quality of life. Most owners (92 %) were satisfied with the surgical outcome. The occurrence of postoperative complications leading to increased overall costs and culling was the main reason for lower owner satisfaction

Parameterized Post-Newtonian coefficients for Brans-Dicke gravity with d+1 dimensions

We present calculations of Post-Newtonian parameters for Brans-Dicke tensor-scalar gravity in an arbitrary number of compact extra dimensions in both the Jordan and Einstein conformal frames. We find that the parameter gamma, which measures the amount of spacetime curvature per unit mass, becomes a function of omega, the coefficient of the scalar kinetic term in the Brans-Dicke Lagrangian. Experiment has placed strong constraints on gamma which require that omega become negative in the Jordan frame for any number of extra dimensions, highlighting that this formulation is not physical. We also confirm the well-known result that a compact extra dimension can be equivalently viewed as a massless scalar `dilaton.' In the Einstein frame, we find that the behavior of gamma as constrained by experiment replicates that which is predicted by string theory.Comment: 9 pages, accepted in Classical and Quantum Gravit

Adsorption of fullerene and azafullerene on Cu(111) studied by electron energy loss spectroscopy

Fullerene and azafullerene films were studied by electron energy loss spectroscopy in reflection geometry. Compared to C60, (C59N)2 multilayers show additional vibrational modes that are characteristic of the dimer structure. The (C59N)2 is semiconductor-like and giant optically allowed excitonic transitions are found in the gap in drastic contrast with C60. The azafullerene monolayer on Cu(111) no longer shows the presence of dimers, indicating monomer adsorption. Similarly to C60, azafullerene molecules in contact with the metal substrate receive a transferred charge between two and three electrons. However, the C59N appears more covalently bound to Cu because it decomposes when heated above 660 K while C60 only desorbs.

Permian-Triassic red-stained albitized profiles in the granitic basement of the NE Spain: evidence for deep alteration related to the Triassic Palaeosurface

Extensive areas of the Variscan granitic basement in NE Spain display profiles of red-stained albitized facies characterized by albitization of Ca-plagioclase, chloritization of biotite and microclinization of orthoclase, along with the alteration of igneous quartz to secondary CL-dark quartz. These profiles have a geopetal structure beneath the Triassic unconformity, with a very intense and pervasive alteration in the upper part that progressively decreases with depth to 150-200 m where the alteration is restricted to the walls of fractures. The red albitized facies contains secondary maghemite and hematite that indicate oxidizing conditions. Dating of microclinized orthoclase and secondary monazite that have formed in the red-stained albitized facies yielded K-Ar and U-Th-Pbtotal ages of 240 and 250 Ma, respectively, suggesting that the alteration developed during the Permian-Triassic period. The geopetal disposition of the red albitized profile with respect to the Triassic unconformity, its large regional extent, and the fracture-controlled alteration in the lower part of the profile indicate groundwater interaction. The δ18O values of albitized plagioclase (+ 11¿), microclinized orthoclase (+ 13¿), and secondary CL-dark quartz (+ 12¿) suggest that the alteration temperature was about 55 °C. This 'low' temperature suggests that the alteration occurred during interaction of the granitic rocks with Na-rich fluids below a surficial weathering mantle on the Permian-Triassic palaeosurface. The latter is possibly related to Triassic evaporitic environments in long-lasting, stable landscapes in which Na-rich solutions infiltrated deep regional groundwaters

Solutions of multigravity theories and discretized brane worlds

We determine solutions to 5D Einstein gravity with a discrete fifth dimension. The properties of the solutions depend on the discretization scheme we use and some of them have no continuum counterpart. In particular, we find that the neglect of the lapse field (along the discretized direction) gives rise to Randall-Sundrum type metric with a negative tension brane. However, no brane source is required. We show that this result is robust under changes in the discretization scheme. The inclusion of the lapse field gives rise to solutions whose continuum limit is gauge fixed by the discretization scheme. We find however one particular scheme which leads to an undetermined lapse reflecting the reparametrization invariance of the continuum theory. We also find other solutions, with no continuum counterpart with changes in the metric signature or avoidance of singularity. We show that the models allow a continuous mass spectrum for the gravitons with an effective 4D interaction at small scales. We also discuss some cosmological solutions.Comment: 19 page

Aetiology of canine infectious respiratory disease complex and prevalence of its pathogens in Europe

The canine infectious respiratory disease complex (CIRDC) is an endemic worldwide syndrome involving multiple viral and bacterial pathogens. Traditionally, Bordetella bronchiseptica (Bb), canine adenovirus type 2 (CAV-2), canine distemper virus (CDV), canine herpesvirus (CHV) and canine parainfluenza virus (CPiV) were considered the major causative agents. Lately, new pathogens have been implicated in the development of CIRDC, namely canine influenza virus (CIV), canine respiratory coronavirus (CRCoV), canine pneumovirus (CnPnV), Mycoplasma cynos and Streptococcus equi subspecies zooepidemicus. To better understand the role of the different pathogens in the development of CIRDC and their epidemiological relevance in Europe, prevalence data were collected from peer-reviewed publications and summarized. Evidence of exposure to Bb is frequently found in healthy and diseased dogs and client-owned dogs are as likely to be infected as kennelled dogs. Co-infections with viral pathogens are common. The findings confirm that Bb is an important cause of CIRDC in Europe. CAV-2 and CDV recovery rates from healthy and diseased dogs are low and the most likely explanation for this is control through vaccination. Seroconversion to CHV can be demonstrated following CIRDC outbreaks and CHV has been detected in the lower respiratory tract of diseased dogs. There is some evidence that CHV is not a primary cause of CIRDC, but opportunistically re-activates at the time of infection and exacerbates the disease. The currently available data suggest that CIV is, at present, neither a prevalent nor a significant pathogen in Europe. CPiV remains an important pathogen in CIRDC and facilitates co-infection with other viral and bacterial pathogens. CnPnV and CRCoV are important new elements in the aetiology of CIRDC and spread particularly well in multi-dog establishments. M. cynos is common in Europe and is more likely to occur in younger and kennelled dogs. This organism is frequently found together with other CIRDC pathogens and is significantly associated with more severe respiratory signs. S. zooepidemicus infection is not common and appears to be a particular problem in kennels. Protective immunity against respiratory diseases is rarely complete, and generally only a reduction in clinical signs and excretion of pathogen can be achieved through vaccination. However, even vaccines that only reduce and do not prevent infection carry epidemiological advantages. They reduce spread, increase herd immunity and decrease usage of antimicrobials. Recommending vaccination of dogs against pathogens of CIRDC will directly provide epidemiological advantages to the population and the individual dog

Evaluation, contrôle et prévention du risque de transmission du virus influenza aviaire à l'homme

Since mid-december 2003, an epizootic of highly pathogenic avian influenza (type A, sub-type H5N1) occurs in eastern and south-eastern Asia. This epizootic is historically unprecedented in its virulence, geographical spread, and economic consequences for the agricultural sector. Implications for human health were registered in Vietnam and in Thailand. This paper summarizes the current knowledge about the risk evaluation of the transmission of avian influenza virus to humans. The current asian epizootic has highlighted the key role of global health information systems and also the need for exhaustive notification of human and animal cases. It reinforces the concept of veterinary public health

Boundary Terms and Junction Conditions for Generalized Scalar-Tensor Theories

We compute the boundary terms and junction conditions for Horndeski's panoptic class of scalar-tensor theories, and write the bulk and boundary equations of motion in explicitly second order form. We consider a number of special subclasses, including galileon theories, and present the corresponding formulae. Our analysis opens up of the possibility of studying tunnelling between vacua in generalized scalar-tensor theories, and braneworld dynamics. The latter follows because our results are independent of spacetime dimension.Comment: 13 pages, Equation corrected. Thanks to Tsutomu Kobayashi for informing us of the typ

Consistent Group and Coset Reductions of the Bosonic String

Dimensional reductions of pure Einstein gravity on cosets other than tori are inconsistent. The inclusion of specific additional scalar and p-form matter can change the situation. For example, a D-dimensional Einstein-Maxwell-dilaton system, with a specific dilaton coupling, is known to admit a consistent reduction on S^2= SU(2)/U(1), of a sort first envisaged by Pauli. We provide a new understanding, by showing how an S^3=SU(2) group-manifold reduction of (D+1)-dimensional Einstein gravity, of a type first indicated by DeWitt, can be broken into in two steps; a Kaluza-type reduction on U(1) followed by a Pauli-type coset reduction on S^2. More generally, we show that any D-dimensional theory that itself arises as a Kaluza U(1) reduction from (D+1) dimensions admits a consistent Pauli reduction on any coset of the form G/U(1). Extensions to the case G/H are given. Pauli coset reductions of the bosonic string on G= (G\times G)/G are believed to be consistent, and a consistency proof exists for S^3=SO(4)/SO(3). We examine these reductions, and arguments for consistency, in detail. The structures of the theories obtained instead by DeWitt-type group-manifold reductions of the bosonic string are also studied, allowing us to make contact with previous such work in which only singlet scalars are retained. Consistent truncations with two singlet scalars are possible. Intriguingly, despite the fact that these are not supersymmetric models, if the group manifold has dimension 3 or 25 they admit a superpotential formulation, and hence first-order equations yielding domain-wall solutions.Comment: Latex, 5 figures, 45 pages, minor correction