294 research outputs found

    Erosion of metals by multiple impacts with water

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    Investigation determines - relation between impact velocity and minimum number of impacts producing visible erosion, relation between high frequency fatigue stresses and number of cycles to failure, water-hammer stresses relation to high frequency endurance limit, erosion rate as exposure time function, and correlates experimental data with recent theory

    Experimental and analytical investigations on multiple liquid impact erosion

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    Experimental and analytical studies of multiple liquid impact erosion of aluminum and stainless stee

    Cavitation damage in liquid metals technical progress report no. 467-3, 1 apr. - 31 may 1965

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    Cavitation damage resistance of refractory alloys in high temperature liquid sodiu

    Cavitation damage in liquid metals technical progress report, 1 jan. - 31 mar. 1965

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    Temperature effect on rate of cavitation damage of 316 stainless steel in pure liquid sodium at temperatures up to 1500 deg

    Cavitation damage in liquid metals Final report

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    Cavitation damage resistance, high frequency fatigue, and stress corrosion behavior of metals in high temperature liquid sodiu

    Cavitation damage in liquid metals /potassium studies/ Technical progress report 1 Nov. - 31 Dec. 1966

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    Cavitation damage resistance of refractory and stainless steel alloys in liquid potassium at high temperature

    Cavitation damage in liquid metals - Potassium studies Final report

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    Cavitation erosion in high purity liquid potassium at high temperatur

    Prognostic scoring system and risk stratification in patients with emphysematous pyelonephritis: an 11‐year prospective study at a tertiary referral centre

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    Objectives: To define pre‐morbid, clinical, laboratory, and imaging features and identify prognostic factors associated with morbidity and mortality in patients with emphysematous pyelonephritis (EPN) and develop a prognostic scoring system for improving management outcomes. / Patients and Methods: From January 2009 to December 2019, we performed a prospective study of all patients with a suspected diagnosis of EPN referred to a specialist tertiary centre in South India. All patients who underwent non‐contrast computed tomography of the abdomen and those diagnosed with EPN were included in this study. Demographic parameters, imaging, haematological and microbiology results were recorded. Patients were divided into three groups: Group 1, patients who survived without any intervention; Group 2, those who survived with surgical intervention; and Group 3, those who died with or without intervention. A prognostic scoring system was developed from 18 different parameters and risk stratification was developed. The scores were correlated with overall prognosis. / Results: Data from 131 patients with EPN enrolled in the study were analysed: Group 1 (n = 22), Group 2 (n = 102) and Group 3 (n = 7). By using univariate analysis, 10 factors were identified to be significantly associated with prognosis. Diabetes mellitus was the most common comorbidity. Shock at initial admission indicated a poor prognosis and warranted immediate attention (P < 0.001). / Conclusions: A multi‐disciplinary approach, a high index of clinical suspicion, an early diagnosis and administration of culture‐specific antibiotics with identification of prognostic indicators and risk stratification, allows prompt and appropriate medical and surgical treatments that could improve EPN management outcomes

    Evaluation of Heavy- and Medium-Duty On-Road Vehicle Emissions in California\u27s South Coast Air Basin

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    Emission measurements were collected from heavy-duty (HDVs) and medium-duty vehicles (MDVs) at the Peralta weigh station long-term measurement site near Anaheim, CA in 2017. Two Fuel Efficiency Automobile Test units sampled elevated and ground-level exhaust vehicles totaling 2,315 measurements. HDVs (1844 measurements) exhibited historical reductions in fuel specific oxides of nitrogen (NOx) from the 2008 measurements (55%) with increased use of exhaust gas recirculation and selective catalytic reduction systems. However, as these technologies have aged, the in-use benefits have declined. Infrared %opacity measurements of tailpipe soot decreased 14% since 2012 with increased diesel particulate filter (DPF) use, DPF longevity and fleet turnover. 63% of the HDV fleet in 2017 was chassis model year 2011+ compared to only 12% in 2012. The observed MDV fleet (471 measurements) was 1.4 years older than the HDV fleet with average NOx 14% higher. A significant reduction in MDV NOx occurred approximately 2 model years prior to similar HDV reductions (2014 versus 2016 chassis model year). MDV chassis model years 2014+ were able to meet their corresponding NOx laboratory certification standards in-use, whereas HDVs remain slightly above this threshold. Similar MDV NOx emission trends were also observed in data previously collected in Chicago, IL

    Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment

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    Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the USA, accounting for ~40,000 deaths annually. The dismal prognosis for PDAC is largely due to its late diagnosis. Currently, the most sensitive diagnosis of PDAC requires invasive procedures, such as endoscopic ultrasonography, which has inherent risks and accuracy that is highly operator dependent. Here we took advantage of a general characteristic of solid tumors, the acidic microenvironment that is generated as a by-product of metabolism, to develop a novel approach of using pH (Low) Insertion Peptides (pHLIPs) for imaging of PDAC. We show that fluorescently labeled pHLIPs can localize and specifically detect PDAC in human xenografts as well as PDAC and PanIN lesions in genetically engineered mouse models. This novel approach may improve detection, differential diagnosis and staging of PDAC
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