Online encoder-decoder anomaly detection using encoder-decoder architecture with novel self-configuring neural networks & pure linear genetic programming for embedded systems

Recent anomaly detection techniques focus on the use of neural networks and an encoder-decoder architecture. However, these techniques lead to trade offs if implemented in an embedded environment such as high heat management, power consumption and hardware costs. This paper presents two related new methods for anomaly detection within data sets gathered from an autonomous mini-vehicle with a CAN bus. The first method which to the best of our knowledge is the first use of encoder-decoder architecture for anomaly detection using linear genetic programming (LGP). Second method uses self-configuring neural network that is created using evolutionary algorithm paradigm learning both architecture and weights suitable for embedded systems. Both approaches have the following advantages: it is inexpensive regarding resource use, can be run on almost any embedded board due to linear register machine advantages in computation. The proposed methods are also faster by at least one order of magnitude, and it includes both inference and complete training

Case Report: Extreme Levels of Serum S-100B in a Patient with Chronic Subdural Hematoma.

The protein S-100B is a biomarker increasingly used within neurosurgery and neurointensive care. As a relatively sensitive, yet unspecific, indicator of CNS pathology, potential sources of error must be clearly understood when interpreting serum S-100B levels. This case report studied the course of a 46-year-old gentleman with a chronic subdural hemorrhage, serum S-100B levels of 22 μg/l, and a history of malignant melanoma. Both intra- and extra-cranial sources of S-100B are evaluated and imply an unclear contribution of several sources to the total serum concentration. Potential sources of error when interpreting serum concentrations of S-100B are discussed

Lärares uppfattning av hur undervisningen i svenska och engelska påverkas av en-till-en

Sammanfattning: Tillgången till informationsteknik har ökat i skolan, bland annat har distributionsmodellen en-till-en – en dator till varje elev och lärare – blivit allt vanligare. Detta innebär förändringar för undervisningen och ställer lärare inför nya utmaningar och situationer. Av det skälet har lärarperspektivet lyfts fram i denna uppsats som syftar till att undersöka hur lärare uppfattar att undervisningen i svenska och/eller engelska påverkas av en-till-en. Denna påverkan har även ställts i relation till de ämnesdidaktiska synsätt som finns inom respektive ämne. Metoden är en kombination av intervjuer och klassrumsobservationer. Undersökningen har genomförts vid en kommunal gymnasieskola i Göte- borgsregionen och omfattar tio lärarintervjuer samt nio klassrumsobservationer. Materialet har bearbetats utifrån en fenomenografisk forskningsansats. Resultatet redovisas utifrån uppsatsens frågeställningar, under vardera frågeställ- ningen presenteras de uppfattningskategorier som gått att urskilja. Lärarnas sätt att erfara teknikens påverkan har delats in i fyra kategorier: lärare och elever får tillgång till ett smidigt arbetsredskap, lärarens kontroll över ämnesin- nehållet utmanas, tillgängligheten i tid och rum utmanar det fysiska klassrummets betydelse och digitalt material kan gestaltas på annat sätt och i andra aktiviteter. Lärarnas uppfattningar kring teknikens påverkan på deras ämnesdidak- tiska synsätt har delats in i tre kategorier: oförändrat, förstärkt och förskjutet ämnesdidaktiskt synsätt. Lärarna ger även uttryck för att pedagogiska aspekter utöver de ämnesdidaktiska frågorna påverkas av tekniken: lärarens ledar- skap utmanas och lärarens fostransuppdrag aktualiseras i ett nytt sammanhang. Resultatet diskuteras i relation till TPACK som är en modell för att beskriva teknikens relation till ämnesdidaktik. Resultatet diskuteras även i relation till forskning om ämnesdidaktiska synsätt och forskning om undervisning i en-till-en-miljöer. Studiens slutsatser pekar på att tekniken har blivit en självklar del i lärarnas sätt att erfara undervisningen i en-till-en-miljön. Däremot är tekniken inte alltid en integrerad del av lärarnas sätt att erfara undervisningens syfte och mål. Detta tyder på att det kan finnas ett behov av didaktisk reflektion kring hur teknik kan användas på ett sätt som tydligare samspelar med undervisningens ämnesinnehåll och didaktiska synsätt och tydligare tillvaratar de kvaliteter som en-till-en kan inne- bära i språkundervisning

Increased use of ruins through secured masonry and comfortable climate

This paper presents a unique scientific research project, funded by the KK-foundation in Sweden together with several companies participating in the project. A primary goal is to find methods to examine and take care of open masonry constructions thereby enabling an increased use of them in a safe and comfortable way without diminishing their cultural values. A second goal is to establish a long-term cooperation/network of researchers, conservators, engineers, antiquarians and craftsmen that can keep and develop the knowledge. The project takes place in year 2010 and 2011. This paper presents a model of cooperation as well as the ongoing experiment and expected results. The project is divided into three major parts:1) Description and assessment of historic masonry as load bearing structures. 2) Assessment of stone and mortar in old masonry and finding the methods to secure and preserve them. 3) The climate in the ruin with respect to comfort and preservation. The goals for the different parts of this research project are to find the best possible solutions of how to: a) Evaluate the construction of complex masonry structures to enable new additions that are appropriate with respect to statics. b) Find efficient methods to evaluate and conserve the status of the materials (stone, mortar) and walls in old masonry to grant safe accessibility. c) Create a comfortable climate in an open masonry structure without closing it. These three research areas all focus on the historic masonry which at the same time forms the climate shell, the bearer of plaster and the historical setting to the activities that are to take place in the ruin

Increased use of ruins through secured masonry and comfortable climate

This paper presents a unique scientific research project, funded by the KK-foundation in Sweden together with several companies participating in the project. A primary goal is to find methods to examine and take care of open masonry constructions thereby enabling an increased use of them in a safe and comfortable way without diminishing their cultural values. A second goal is to establish a long-term cooperation/network of researchers, conservators, engineers, antiquarians and craftsmen that can keep and develop the knowledge. The project takes place in year 2010 and 2011. This paper presents a model of cooperation as well as the ongoing experiment and expected results. The project is divided into three major parts:1) Description and assessment of historic masonry as load bearing structures. 2) Assessment of stone and mortar in old masonry and finding the methods to secure and preserve them. 3) The climate in the ruin with respect to comfort and preservation. The goals for the different parts of this research project are to find the best possible solutions of how to: a) Evaluate the construction of complex masonry structures to enable new additions that are appropriate with respect to statics. b) Find efficient methods to evaluate and conserve the status of the materials (stone, mortar) and walls in old masonry to grant safe accessibility. c) Create a comfortable climate in an open masonry structure without closing it. These three research areas all focus on the historic masonry which at the same time forms the climate shell, the bearer of plaster and the historical setting to the activities that are to take place in the ruin

Increased use of ruins through secured masonry and comfortable climate

This paper presents a unique scientific research project, funded by the KK-foundation in Sweden together with several companies participating in the project. A primary goal is to find methods to examine and take care of open masonry constructions thereby enabling an increased use of them in a safe and comfortable way without diminishing their cultural values. A second goal is to establish a long-term cooperation/network of researchers, conservators, engineers, antiquarians and craftsmen that can keep and develop the knowledge. The project takes place in year 2010 and 2011. This paper presents a model of cooperation as well as the ongoing experiment and expected results. The project is divided into three major parts:1) Description and assessment of historic masonry as load bearing structures. 2) Assessment of stone and mortar in old masonry and finding the methods to secure and preserve them. 3) The climate in the ruin with respect to comfort and preservation. The goals for the different parts of this research project are to find the best possible solutions of how to: a) Evaluate the construction of complex masonry structures to enable new additions that are appropriate with respect to statics. b) Find efficient methods to evaluate and conserve the status of the materials (stone, mortar) and walls in old masonry to grant safe accessibility. c) Create a comfortable climate in an open masonry structure without closing it. These three research areas all focus on the historic masonry which at the same time forms the climate shell, the bearer of plaster and the historical setting to the activities that are to take place in the ruin

Recrystallization of waxy maize starch during manufacturing of starch microspheres for drug delivery: Influence of excipients

The formation of ordered structure, such as crystallites, in starch was studied by means of differential scanning calorimetry (DSC). The influence of time/temperature treatment and additives such as polyethylene glycol (PEG), bovine serum albumin (BSA) and a carbonate buffer on the formation was investigated. The experiments were planned with a CCC (Central Composite Circumscribed) design. For all three investigated systems it could be concluded that the incubation time at 6 °C was the decisive factor for the amount of ordered structure obtained during the incubation, while the incubation time at 37 °C was the decisive factor for the thermal stability of the crystallites as expressed by Ton, Tm and Tc. The additives seemed to mainly affect the nucleation phase of crystallization process. The additives decreased the time required in order to obtain a certain level of ordering in the incubated starch samples. The carbonate buffer decreased the amount of ordered structure in starch as judged by DSC enthalpy values, while increasing the melting temperature of these structures. The additives PEG and BSA lowered the melting temperatures of the starch in the systems but increased the enthalpy values. By optimization procedure a specific amount of ordered structure with desired thermal characteristics could be predicted

Exploring gender dysphoria and related outcomes in a prospective cohort study : protocol for the Swedish Gender Dysphoria Study (SKDS)

INTRODUCTION: There has been a drastic increase in the reported number of people seeking help for gender dysphoria in many countries over the last two decades. Yet, our knowledge of gender dysphoria and related outcomes is restricted due to the lack of high-quality studies employing comprehensive approaches. This longitudinal study aims to enhance our knowledge of gender dysphoria; different aspects will be scrutinised, focusing primarily on the psychosocial and mental health outcomes, prognostic markers and, secondarily, on the underlying mechanisms for its origin. METHODS AND ANALYSIS: The Swedish Gender Dysphoria Study is an ongoing multicentre longitudinal cohort study with 501 registered participants with gender dysphoria who are 15 years old or older. Participants at different phases of their clinical evaluation process can enter the study, and the expected follow-up duration is three years. The study also includes a comparison group of 458 age- and county-matched individuals without gender dysphoria. Data on the core outcomes of the study, which are gender incongruence and experienced gender dysphoria, body satisfaction and satisfaction with gender-affirming treatments, as well as other relevant outcomes, including mental health, social functioning and life satisfaction, are collected via web surveys. Two different research visits, before and after starting on gender-affirming hormonal treatment (if applicable), are planned to collect respective biological and cognitive measures. Data analysis will be performed using appropriate biostatistical methods. A power analysis showed that the current sample size is big enough to analyse continuous and categorical outcomes, and participant recruitment will continue until December 2022. ETHICS AND DISSEMINATION: The ethical permission for this study was obtained from the Local Ethical Review Board in Uppsala, Sweden. Results of the study will be presented at national and international conferences and published in peer-reviewed journals. Dissemination will also be implemented through the Swedish Gender Dysphoria Study network in Sweden