Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility

Despite advances in the field of male reproductive health, idiopathic male infertility, in which a man has altered semen characteristics without an identifiable cause and there is no female factor infertility, remains a challenging condition to diagnose and manage. Increasing evidence suggests that oxidative stress (OS) plays an independent role in the etiology of male infertility, with 30% to 80% of infertile men having elevated seminal reactive oxygen species levels. OS can negatively affect fertility via a number of pathways, including interference with capacitation and possible damage to sperm membrane and DNA, which may impair the sperm’s potential to fertilize an egg and develop into a healthy embryo. Adequate evaluation of male reproductive potential should therefore include an assessment of sperm OS. We propose the term Male Oxidative Stress Infertility, or MOSI, as a novel descriptor for infertile men with abnormal semen characteristics and OS, including many patients who were previously classified as having idiopathic male infertility. Oxidation-reduction potential (ORP) can be a useful clinical biomarker for the classification of MOSI, as it takes into account the levels of both oxidants and reductants (antioxidants). Current treatment protocols for OS, including the use of antioxidants, are not evidence-based and have the potential for complications and increased healthcare-related expenditures. Utilizing an easy, reproducible, and cost-effective test to measure ORP may provide a more targeted, reliable approach for administering antioxidant therapy while minimizing the risk of antioxidant overdose. With the increasing awareness and understanding of MOSI as a distinct male infertility diagnosis, future research endeavors can facilitate the development of evidence-based treatments that target its underlying cause

VARICOCELE INDUCE OXIDATIVE STRESS AND SPERM DNA DAMAGES IN INFERTILES PATIENTS.

76th Scientific Congress of the American-Society-for-Reproductive-Medicine, ELECTR NETWORK, OCT 17-21, 2020International audienc

FOOD WASTAGE BY TUNISIAN HOUSEHOLDS

Food waste (FW) is seen as an obstacle to achieving food and nutrition security andfood systems sustainability. It is known in literature that households are significantcontributors to the total amount of FW. This paper reports on results of an onlinesurvey that was conducted from February to April 2015 with a random sample of281 Tunisian adults. The aim of the survey is to assess the knowledge and relativeimportance of FW; attitudes towards FW; impacts of behaviors regarding food andfood management; quantity and value of FW; as well as barriers and willingness tobehavioral change. The sample was not gender-balanced (71.2% female and 28.8%male). The majority of the respondents was young (70.8% aged between 18 and 34years) and has high education level (95.4% having university and PhD degrees).Food waste is prevalent in Tunisia as about the half of respondents declare thatthey throw food. The most wasted food products are fruits, vegetables, and cerealsand bakery products. Only 42.7% of respondents declared that the economic valueof food waste generated each month is more than 6US$. Most of Tunisianrespondents have a good understanding of food labels that is probably due to thehigh education level of the sample. About 37% of respondents throw weekly atleast 250 g of still consumable food. To reduce FW in Tunisia it is important to seta strategy at all food chain levels. There is also an urgent need to raise people’s andorganizations awareness towards this problem. This article provides a basis for thedevelopment of other more context specific investigations and interventions for theprevention of household FW in Tunisia