Chemical characterization of an encapsulated red wine powder and its effects on neuronal cells

Red wine polyphenols are known for their implications for human health protection, although they suffer from high instability. For this reason, a red wine powder was prepared by freeze-drying encapsulation in maltodextrin/arabic gum matrix, and its composition was determined by means of high-performance liquid chromatography coupled quadrupole time-of-flight mass spectrometry (HPLC-MS-QTOF). More than thirty polyphenols, including anthocyanins, flavanols, flavonols, phenolic acids and stilbenoids, were identified. Some of the main quantified polyphenols were: malvidin-3-O-glucoside, malvidin 3-O-(6”-acetyl-glucose), petunidin-3-O-glucoside, quercetin-3-O-glucuronide, syringenin-3-O-glucoside, epicatechin, gallic acid and syringic acid. The biological activity of this de-alcoholized and encapsulated red wine on human neuroblastoma SH-SY5Y cells was studied. The results showed that the encapsulated red wine powder has active redox properties, as verified by performing reactive oxygen species (ROS) analysis utilizing a neuronal model. This could help explain its action against the neurotoxicity induced by 6-hydroxydopamine (6-OHDA).Fil: Rocha Parra, Diego Fernando. Consejo Superior de Investigaciones Científicas. Instituto de Ciencia y Tecnologia de Alimentos y Nutrición; España. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chirife, Jorge. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Zamora, María Clara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: de Pascual Teresa, Sonia. Consejo Superior de Investigaciones Científicas. Instituto de Ciencia y Tecnologia de Alimentos y Nutrición; Españ

Modelización fotorrealística de emplazamientos de interés cultural

Peer Reviewe

Standardization of a new photodiagnosis method based on LEDs for patients with solar urticaria sensitive to visible light

Standard methods for photodiagnosis of solar urticaria are based in exposure of patient skin to different polychromatic UV and visible sources where minimal urticarial doses for different spectral bands (UVB and UVA) are established. Classical photodiagnosis devices are based in solar simulation and use of UVB and UVA enhanced fluorescent lamps. In case of visible US photodiagnosis, US patient skin is exposed for 15 min to a slight projector, provided with halogen lamp, at a distance of 15 cms and presence of erythema and/or wheals is determined as positive reaction. Slights projector is from several years almost out of market due to use of new projection digital technologies and new visible light emerging technologies are good candidates for their substitution as photodiagnosis tool. The objective of the present work is to analyze photodiagnosis of visible light solar urticaria with using a LED device in comparison to normal slight projector exposure protocol. A total of twenty patients, from 7 different photodiagnosis units have participated in the study. Patients, with SU positive to visible light (with or without to UV radiation) following the standard photodiagnosis protocols were included in the study. Slight projector used in all photodiagnosis units were of similar characteristics and irradiance at 15 cm distance, as well as total dose of visible light after 15 min were calculated for each halogen lamp device. LED exposure was performed in parallel in a closed zone of the back of the patients. For LED photodiagnosis a prototype from University of Málaga (Spain) has been developed consisting in a black box provided with 4 holes of 12 mm diameter in which each hole white warm of a LED of 1 W is emitted. Thus, each LEDs dose is controlled independently and the device allows establishing, as well as for UVB and UVA normal protocols a MUD also under visible light. In that case, maximal visible light dose is reached in less than 5 min compared to 15 min under exposure to slight projector. All patients were positive to LED warm visible light with presence of erythema and / or wheals in parallel to the exposure to the slight projector. A MUD to visible light has been established with significant variations between patients which reveals different grade to visible light sensibilization. In conclusion, a new technology of illumination based in LEDs can be used in photodiagnosis of SU.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Las Ordenanzas de las Aguas de Granada.

Sin resume

Los gremios granadinos a través de sus ordenanzas.

Sin resume

Historia general de los religiosos descalzos del orden de los ermitaños del gran padre, y doctor de la Iglesia San Agustin, de la Congregacion de España, y de las Indias

Copia digital : Junta de Castilla y León. Consejería de Cultura y Turismo, 2014Sign. : []4, 2[parágrafo]-3[parágrafo]4, 2A-2Z4, 3A-3Z4, 4A-4B4, 5C6.Grab. calcográfico en [parágrafo]3 de "Valls Del. Sculp. Barcin."Texto a dos col.Port. con orla tip.Port. frontispicia grab. calc. "Pº a Villa franca Sculptor Regis, scupsit Matriti, 1663

Historia de la prodigiosissima imagen de Nuestra Señora del Niño Perdido : venerada en el ... colegio de Jesus de Nazareno de Agustinos Descalzos, en la Villa de Caudièl ... ; añadese ... la vida del ... Hermano Juan de la Virgen del Niño Perdido

ÍndiceSign. : [sol]-4[sol]4, A-Lll4Letras iniciales decoradas, frisos tip. y viñetas xilApostillas marginales y reclamosLas h. de grab representan a la Virgen del Niño Perdido y el escudo de D. Antonio del Valle Monsoriu, y Landà

Host/Guest Simulation of Fluorescent Probes Adsorbed into Low-Density Polyethylene, 1. Excimer Formation of 1,3-Di(1-pyrenyl)propane

Molecular dynamics and Rotational Isomer State/Monte Carlo techniques with a Dreiding 1.01 Force Field are employed to study the excimer formation of isolated 1,3-di(1-pyrenyl)propane and the probe adsorbed into a low-density polyethylene (LDPE) matrix model. The probability of formation of each molecular conformer at several temperatures was calculated using these theoretical techniques. Conformational statistical analysis of the four torsion angles (ϕ₁, ϕ₂, θ₁, θ₂) of Py3MPy showed that the angles —C—Cᵃʳ— (ϕ₁, ϕ₂) present two states c ± = ±90°; and the angles —C—C— (θ₁, θ₂), the three trans states = 180°, g ± = ±60°. The correlation of θ₁–θ₂ torsion angles showed that the most probable pairs were g⁺g⁻ and g⁻g⁺ for the excimer-like specimens, although these angles are distorted because of interactions with the polymer matrix. The temperature dependence of the excimer-formation probability revealed that this process was thermodynamically controlled in the isolated case. When the probe was adsorbed into the LDPE matrix, the excimer formation process was reversed at T = 375 K. At T > 375 K, the behavior was similar to the isolated case but, at T < 375 K, excimer formation probability increased with temperature as found experimentally by steady-state fluorescence spectroscopy. This temperature was coincident with the onset of the LDPE melting process, determined experimentally by thermal analysis.The authors wish to thank Brite EuRam programme (BE97-4472) and CAM (07N/0002/1998) for support

Chemical looping combustion of biomass with negative CO2 emissions

CO2 emissions to the atmosphere became an important environmental problem because of the effect on the global warming and consequently, the climate change. The climate change challenge demands a commitment of combined strategies between global institutions, governments and citizens. To reach the objectives set in the Paris Agreement (2015), greenhouse gas emissions need to be reduced. No technology is currently able to achieve the necessary reductions in greenhouse gas emissions on its own. Biomass represents an interesting alternative fuel for heat and power production as a carbon dioxide-neutral fuel. Moreover, if the CO2 generated during biomass combustion process is captured then negative-CO2 emissions would be reached and these are named bioenergy with Carbon Capture and Storage (BECCS) technologies.Chemical Looping Combustion (CLC) came up as one of the most promising CO2 capture technologies thanks to the low energy penalty of the CO2 separation and therefore, low-cost. CLC technologies are based in two interconnected fluidized bed reactors without gas mixing. The combustion takes place in the fuel reactor where the oxygen is supplied by a solid oxygen carrier, normally metal oxides. After being reduced, the oxygen carrier goes to the air reactor without gas mixing between reactors where it is oxidized again in air, and it is able for a new redox cycle starts.The main objective of this thesis is to evaluate the biomass combustion with CLC technologies (bioCLC). The research plan covers studies different at different scales, starting at lab scale, through a 1 kWth pilot plant, to the continuous operation in a 20 kWth plant to demonstrate the viability and optimizing the operation range for different low-cost oxygen carriers and different types of biomass residues.Iron based ores as well as manganese ores has been pointed as promising oxygen carriers because of their reactivity and low cost. Under In Situ Gasification Chemical Looping Combustion (iG-CLC) mode, the performance of the process was studied focusing on the effect of different important operating variables in a 1 kWth CLC unit. Values about 100% of carbon capture efficiency with the three types of biomass were obtained using ores as oxygen carrier and the total oxygen demand was reduced because of the different reactivity of each oxygen carrier and the operating conditions optimization. Also a synthetic iron-manganese mixed able to release molecular oxygen during the CLC process was used. The effect of the several operating variables was also studied finding a high dependency on the air excess and the temperature, both in the air reactor, on the CO2 capture efficiency and the total oxygen demand. About 100% of CO2 capture efficiency achieving values of total oxygen demand about 5%. The use of a mixed Cu-Mn oxide was also studied as a Chemical Looping with Oxygen Uncoupling (CLOU) oxygen carrier. High CO2 capture efficiencies were obtained and close to null total oxygen demand wasachieved.The effect of the operating conditions on the performance of CLC was evaluated in a 20 kWth CLC unit using an iron ore as oxygen carrier. A Spanish biomass residue was tested achieving values close to 100% and total oxygen demands between 15-20% despite the low temperature used, supporting the consideration of the CLC process with biomass (bioCLC) as a promising bioenergy with Carbon Capture (BECCS) technology.One of the aspects to be considered in the combustion of biomass is the formation of NOx and the possible existence of tar in the gaseous product stream. This work compares the results obtained with two different chemical looping combustion modes, iG-CLC and CLOU.All these results show the feasibility of the integration of solid biofuels with CLC technologies achieving a negative emission technology able to produce an energy gain through a BECCS technology.<br /