Severe ovarian hyperstimulation syndrome in spontaneous pregnancy treated successfully with cabergoline

Ovarian hyperstimulation syndrome (OHSS) is a relatively common complication in infertile patients treated with exogenous gonadotropins. Ovarian hyperstimulation in spontaneous pregnancies is a rare but possible. The pathogenesis of spontaneous OHSS is not well known. Risk factors for OHSS are young age, polycystic ovaries, low body mass index, high gonadotropin dose, increased estradiol and human chorionic gonadotropin levels, multiple pregnancy, OHSS history, molar pregnancy and hypothyroidism. In this report we present a case of severe spontaneous OHSS with a brief summary of the literature. She was hospitalized and treated in the clinic with the diagnosis of severe OHSS accompanying spontaneous pregnancy

Threshold Tolerance of New Genotypes of Pennisetum glaucum (L.) R. Br. to Salinity and Drought

With continued population growth, increasing staple crop production is necessary. However, in dryland areas, this is negatively affected by various abiotic stresses, such as drought and salinity. The field screening of 10 improved genetic lines of pear millet originating from African dryland areas was conducted based on a set of agrobiological traits (i.e., germination rate, plant density, plant maturity rate, forage, and grain yields) in order to understand plant growth and its yield potential responses under saline environments. Our findings demonstrated that genotype had a significant impact on the accumulation of green biomass (64.4% based on two-way ANOVA), while salinity caused reduction in grain yield value. HHVBC Tall and IP 19586 were selected as the best-performing and high-yielding genotypes. HHVBC Tall is a dual purpose (i.e., forage and grain) line which produced high grain yields on marginal lands, with soil salinization up to electrical conductivity (EC) 6–8 dS m−1 (approximately 60–80 mM NaCl). Meanwhile, IP 19586, grown under similar conditions, showed a rapid accumulation of green biomass with a significant decrease in grain yield. Both lines were tolerant to drought and sensitive to high salinity (above 200 mM NaCl). The threshold salinity of HHVBC Tall calculated at the seedling stage was lower than that of IP 19586. Seedling viability of these lines was affected by oxidative stress and membrane peroxidation, and they had decreased chlorophyll and carotenoid biosynthesis. This study demonstrated that ionic stress is more detrimental for the accumulation of green and dry biomass, in combination with increasing the proline and malonic dialdehyde (MDA) contents of both best-performing pearl millet lines, as compared with osmotic stress

A rare case of Double Superior Vena Cava, diagnosed after Central Line placement, in a poly-trauma patient

Health professionals involved in invasive procedures such as central venous catheter placement should have a thorough knowledge of thoracic vascular anatomy. Various developmental anomalies of the large intra-thoracic veins can be incidentally discovered in normal adults. Amongst these congenital anomalies is a duplication of superior vena cava (SVC), which results from failure of the left superior cardinal vein to obliterate. Awareness about this anomaly and its variations is important to help overcome challenges in procedures, as well as avoid complications. In this article, we present a case of incidentally diagnosed double-SVC in an adult polytrauma patient after central line insertion in the Trauma Intensive care Unit.qscienc

Rational design of EDTA-incorporated nanoflowers as novel and effective endodontic disinfection against biofilms

The ethylenediaminetetradiacetic acid (EDTA) is one of the most commonly used irrigation solutions. Although EDTA has a very low antimicrobial property, it is used to remove inorganic part of smear layer in areas of root canal system. Herein, we developed EDTA-incorporated nanoflowers (EDTA NFs), for the first time, as novel and effective irrigation solution with quite high antimicrobial property to provide complete disinfection in root canal system. We both systematically elucidated the formation of the EDTA NFs with various techniques, and their catalytic and antimicrobial activities in the presence of hydrogen peroxide (H2O2) were documented through intrinsic EDTA property and peroxidase-like activities

In Situ Synthesis of Horseradish Peroxidase Nanoflower@Carbon Nanotube Hybrid Nanobiocatalysts with Greatly Enhanced Catalytic Activity

Organic–inorganic hybrid nanoflowers (NFs) consisting of horseradish peroxidase (HRP) and copper II (Cu2+) are successfully synthesized with the involvement of carbon nanotubes (CNTs) by in situ and post-modification methods. Catalytic activities of in situ synthesized HRP-NF@CNT (HRP-NF@CNT-Is) and post-modification-synthesized HRP-NF@CNTs (HRP-NF@CNT-Pm) are systematically examined. The 30 mg CNTs incorporated HRP-NF@CNT-Is (HRP-NF@CNT-30Is) exhibits greatly increased catalytic activity and stability toward 3,3′,5,5′-tetramethylbenzidine (TMB), thanks to the synergistic effect between HRP-NF and CNTs and the peroxidase-like activity of CNTs in the presence of hydrogen peroxide (H2O2). While HRP-NF@CNT-30Is retains almost 85% of its initial activity even after 10 cycles, HRP-NF (without CNTs) loses half of its initial activity at the same experimental conditions. We study how two experimental parameters, the pH values and temperatures, influence the catalytic activity of HRP-NF@CNT-30Is, in addition to the fact that HRP-NF@CNT-30Is is employed to detect the presence of H2O2 and glutathione (GSH) with colorimetric and spectrophotometric readouts. For instance, HRP-NF@CNT-30Is is used to sensitively detect H2O2 in the range of 20 to 300 μM with an LOD of 2.26 μM. The catalytic activity of HRP-NF@CNT-30Is is suppressed in the presence of GSH, and then an obvious color change from blue to nearly colorless is observed. Using this strategy, GSH is also sensitively determined in the range of 20–200 μM with an LOD of 11.2 μM. We expect that HRP-NF@CNTs can be used as a promising and novel nanobiocatalyst for various biomedical and industrial applications in the near future

Correlation Between DTI Findings and Volume of Corpus Callosum in Children with Autism

Background: Autism Spectrum Disorder (ASD) is a complex developmental disorder in which neurological basis is largely unknown. The Corpus Callosum (CC) is the main commissure that connects the cerebral hemispheres. Previous evidence suggests the involvement of the CC in the pathophysiology of autism

Development of a Colorimetric Urease Test Based on Au NPS Capped with Anthocyanin for the Rapid Detection of Helicobacter pylori through Multiple Readouts

In this work, we have reported use of anthocyanin capped gold nanoparticles (Ant@Au NPs)-incorporated colorimetric urease test for rapid, sensitive and economic detection of Helicobacter pylori (H. pylori). This test containing Ant@Au NPs, urea, sodium phosphate buffer (PBS) and sodium azide (NaN3) was prepared at pH 5 with red solution owing to dispersity of Ant@Au NPs, urease enzyme secreted from H. pylori cause production of ammonia (NH3) via hydrolysis of urea, then which makes reaction environment alkaline (pH 8.2). The limit of detection for this Ant@Au NPs based urease test was determined to be to 102 CFU/mL with proportional to increasing incubation time. However, distinct color change was observed with 104 CFU/mL H. pylori suspensions in 15 min. The anthocyanin molecules existing on surface of Ant@Au NPs were easily deprotonated from hydroxyl groups in the alkaline condition, which caused various changes on Ant@Au NPs including quite much negative charges on the surface of Ant@Au NPs analyzed by Zeta potential, aggregation of Ant@Au NPs demonstrated by STEM, DLS and spectrophotometer, and turning the color of test solution to purple evaluated by a naked eye and digital process imaging system