Managing Diversity and Glass Ceiling Initiatives as National Economic Imperatives

Glass Ceiling ReportGlassCeilingBackground5ManagingDiversity.pdf: 11584 downloads, before Oct. 1, 2020

A Cost-Benefit Analysis of Preserving the Great Barrier Reef

This paper investigates both the economic benefits and costs of protecting Australia’s Great Barrier Reef (GBR). The benefits associated with the Reef come from a 2016 Deloitte Touche Tohmatsu Limited report and quantifies direct economic contributions, nonuse values, and a social, economic, and icon value. The costs of protecting the Reef come from a collection of sources, including the Reef 2050 Long-Term Sustainability Plan, “The Cost and Feasibility of Marine Coastal Restoration”, and a number of annual reports from governmental and non-governmental organizations. By analyzing these documents, the net benefits were calculated. The Great Barrier Reef contributes $6.4 billion to the Australian economy annually, supports 64,000 jobs, and has a total social, economic, and icon value of$56 billion. While there are large monetary benefits associated with the Reef, average costs associated with ensuring the Reef’s survival add up to $264 million annually, and restoration costs of$45,621 for each hectare of reef restored. Of the direct contribution benefits and direct costs, there are net benefits of approximately $6.1 billion each year. However, when looking at the net benefits of restoring the Reef, only 7% of the Reef could be restored while remaining economically efficient. Although the true benefits provided by the Reef are underestimated, and the costs are likely overestimated, the finding of this paper is that the Great Barrier Reef can and should be protected from further damage

FMRI Clustering and False Positive Rates

Recently, Eklund et al. (2016) analyzed clustering methods in standard FMRI packages: AFNI (which we maintain), FSL, and SPM [1]. They claimed: 1) false positive rates (FPRs) in traditional approaches are greatly inflated, questioning the validity of "countless published fMRI studies"; 2) nonparametric methods produce valid, but slightly conservative, FPRs; 3) a common flawed assumption is that the spatial autocorrelation function (ACF) of FMRI noise is Gaussian-shaped; and 4) a 15-year-old bug in AFNI's 3dClustSim significantly contributed to producing "particularly high" FPRs compared to other software. We repeated simulations from [1] (Beijing-Zang data [2], see [3]), and comment on each point briefly.Comment: 3 pages, 1 figure. A Letter accepted in PNA

Hepatic steatosis and fibrosis: Non-invasive assessment

Chronic liver disease is a major cause of morbidity and mortality worldwide and usually develops over many years, as a result of chronic inflammation and scarring, resulting in end-stage liver disease and its complications. The progression of disease is characterised by ongoing inflammation and consequent fibrosis, although hepatic steatosis is increasingly being recognised as an important pathological feature of disease, rather than being simply an innocent bystander. However, the current gold standard method of quantifying and staging liver disease, histological analysis by liver biopsy, has several limitations and can have associated morbidity and even mortality. Therefore, there is a clear need for safe and noninvasive assessment modalities to determine hepatic steatosis, inflammation and fibrosis. This review covers key mechanisms and the importance of fibrosis and steatosis in the progression of liver disease. We address non-invasive imaging and blood biomarker assessments that can be used as an alternative to information gained on liver biopsy

Initial Conditions for Models of Dynamical Systems

The long-time behaviour of many dynamical systems may be effectively predicted by a low-dimensional model that describes the evolution of a reduced set of variables. We consider the question of how to equip such a low-dimensional model with appropriate initial conditions, so that it faithfully reproduces the long-term behaviour of the original high-dimensional dynamical system. Our method involves putting the dynamical system into normal form, which not only generates the low-dimensional model, but also provides the correct initial conditions for the model. We illustrate the method with several examples. Keywords: normal form, isochrons, initialisation, centre manifoldComment: 24 pages in standard LaTeX, 66K, no figure

Hepatocellular carcinoma: Review of disease and tumor biomarkers.

© The Author(s) 2016.Hepatocellular carcinoma (HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative treatments is limited to early stage cancers, diagnosis in non-symptomatic individuals is crucial. International guidelines advise regular surveillance of high-risk populations but the current tools lack sufficient sensitivity for early stage tumors on the background of a cirrhotic nodular liver. A number of novel biomarkers have now been suggested in the literature, which may reinforce the current surveillance methods. In addition, recent metabonomic and proteomic discoveries have established specific metabolite expressions in HCC, according to Warburgs phenomenon of altered energy metabolism. With clinical validation, a simple and non-invasive test from the serum or urine may be performed to diagnose HCC, particularly benefiting low resource regions where the burden of HCC is highest

Reopening Johnson County Hospital: The Beginning of Interprofessional Healthcare Education at ETSU

Johnson County Hospital was a hospital located in Mountain City, TN that existed from 1972 until its final closure in 1998. The hospital faced multiple financial challenges during its existence and was forced to close three times. In 1988 it closed for the penultimate time, and as it had in the past, it counted on the community, local business and local government to reopen the hospital. Three local businessmen were particularly dedicated to reopening the county hospital and reached out to East Tennessee State University (ETSU) and their newly formed College of Medicine. A partnership was formed between the community and ETSU to open a rural campus to educate medical, nursing, public health and allied health students. This rural campus was made a reality through the Kellogg Grant awarded to ETSU in 1991 and was expanded to include graduate medical education in 1996. This collaboration between the community, local businesses, local government and ETSU was able to reopen the hospital in 1992 and jump-started interprofessional education at ETSU which is continued today in the form of the Academic Health Sciences Center and the Interprofessional Education Program