The Use of Colorful Semantics to Improve Sentence Construction in Writing Sentences Among Year Four Pupils

This action research was set out to develop pupils' writing skill using colorful semantics. The main two objectives established from the outset were to develop pupils' sentence construction and improve my teaching practice in sentence construction teaching respectively. As the researcher, I conducted this classroom action research to 31 pupils which comprised 17 males and 14 females of Year 4J of SJK(C) Cheng Siu 2 in Malaysia. The data was gathered through pre- writing test and post- writing test, pupils' work as well as teacher's reflective journal. Over the course of four weeks, I introduced colorful semantics to my pupils in accordance to the sequence of ‘who', ‘what doing', ‘what' and ‘where'. As can be induced from the findings, colorful semantics was statistically significant to pupils' sentence construction through the enhancement of pupils' ability to understand words of each sentence part and also to write sentence in the correct order. The findings also depicted that utilization of colorful semantics improved my teaching practice to become a reflective, passionate, and motivational teacher. Therefore, the positive results warrant further research into colorful semantics with suggestions to integrate Information, Communication, and Technology (ICT) into lessons and expose pupils to more sentence types

Adaptive and coupled continuum-molecular mechanics simulations of amorphous materials

A method to reduce the degrees freedom in molecular mechanics simulation is presented. Although the approach is formulated for amorphous materials in mind, it is equally applicable to crystalline materials. The method can be selectively applied to regions where molecular displacements are expected to be small while simultaneously using classical molecular mechanics (MM) for regions undergoing large deformation. The accuracy and computational efficiency of the approach is demonstrated through the simulation of a polymer-like substrate being indented by a rigid hemispherical indentor. The region directly below the indentor is modelled by classical molecular mechanics while the region further away has the degrees of freedom (DOFs) reduced by about 50 times. The results of automatically reverting regions of reduced DOFs back to classical MM also demonstrate the capability of performing adaptive simulations

Dynamic ATR-FTIR and TEM study of the resin-dentin interface in Reactmer Bond

Abstract no. 895published_or_final_versio

Automated targeting approach for synthesis of heat exchanger network (HEN) with trigeneration system

AbstractIn this work, a novel systematic approach for the synthesis of heat exchanger network (HEN) with trigeneration system via multiple cascades automated targeting (MCAT) is presented. The optimisation objective is to locate the minimum total operating cost (TOC) of the system. The minimum hot and cold utilities of the HEN, allocation of utilities and potential power generation as well as the type of fuel can be determined via proposed approach. A case study of formic acid processing plant is solved to illustrate proposed approach

Defining the Incremental Utility of Prostate Multiparametric Magnetic Resonance Imaging at Standard and Specialized Read in Predicting Extracapsular Extension of Prostate Cancer

AbstractMultiparametric magnetic resonance imaging (mpMRI) is increasingly used in staging early prostate cancer (PCa) but remains heavily reader-dependent. We aim to define the incremental utility of mpMRI over clinical parameters in determining the pathologic extracapsular extension (pECE) of PCa interpreted in a standard radiologic setting and when further over-read by a specialized reader. We retrospectively reviewed 120 men with clinically localized PCa undergoing mpMRI and radical prostatectomy. We obtained radiologic prediction of pECE from standard radiologic reports (standard read) and by a specialized reader blinded to clinical and pathologic findings (specialized read). We determined the incremental benefit of standard read and specialized read by sequential addition to a baseline clinical parameters-only logistic regression model predicting pECE. The sensitivity and specificity of standard read were 77% and 44%, respectively, whereas those of specialized read were 86% and 81%. The positive likelihood ratio was 1.7 at baseline, 1.7 adding standard read, and 6.5 adding specialized read. The negative likelihood ratio was 0.6 at baseline, 0.5 adding standard read, and 0.1 adding specialized read. Standard read modestly improved prediction of pECE, whereas specialized read improved it moderately.Patient summaryThe incremental benefit of mpMRI over clinical information is small but increases to moderate with a specialized second opinion. This second opinion may be useful when considering active surveillance, nerve-sparing surgery, or focal therapy

Numerical Simulation of undular bore evolution with chezy friction, 2015

This paper studies and simulates numerically the evolution of undular bore under the effect of damping in the framework of the perturbed extended Korteweg-de Vries equation. Here, we consider Chezy frictional term to be the damping term in the perturbed extended Korteweg-de Vries equation. Numerical simulations show that under the influence of the friction, the undular bore with thick leading wave will transform into KdV-like solitary wave as the leading wave of the undular bore. The amplitude of the "thick" leading wave will remain the same for some time even though there is dissipation effect

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade

Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and therapy-resistance. In vitro, gelsolin has anti-apoptotic and pro-migratory functions and is critical for invasion of some types of tumor cells. We found that gelsolin was highly expressed at tumor borders infiltrating into adjacent liver tissues, as examined by immunohistochemistry. Although gelsolin contributes to lamellipodia formation in migrating cells, the mechanisms by which it induces tumor invasion are unclear. Gelsolin’s influence on the invasive activity of colorectal cancer cells was investigated using overexpression and small interfering RNA knockdown. We show that gelsolin is required for invasion of colorectal cancer cells through matrigel. Microarray analysis and quantitative PCR indicate that gelsolin overexpression induces the upregulation of invasion-promoting genes in colorectal cancer cells, including the matrix-degrading urokinase-type plasminogen activator (uPA). Conversely, gelsolin knockdown reduces uPA levels, as well as uPA secretion. The enhanced invasiveness of gelsolin-overexpressing cells was attenuated by treatment with function-blocking antibodies to either uPA or its receptor uPAR, indicating that uPA/uPAR activity is crucial for gelsolin-dependent invasion. In summary, our data reveals novel functions of gelsolin in colorectal tumor cell invasion through its modulation of the uPA/uPAR cascade, with potentially important roles in colorectal tumor dissemination to metastatic sites

Quantum Magnetization Plateau in Spin-1 Triangular-Lattice Antiferromagnet Ba3_3NiSb2_2O9_9

We report the results of magnetization and specific heat measurements on Ba$_3$NiSb$_2$O$_9$, which is a quasi-two-dimensional spin-1 triangular-lattice antiferromagnet. We observed a nonclassical magnetization plateau at one-third of the saturation magnetization that is driven by spin frustration and quantum fluctuation. Exact diagonalization for a 21-site rhombic cluster was performed to analyze the magnetization process. Experimental and calculated results agree well.Comment: published in Journal of the Physical Society of Japan 80 (2011) 09370

Supersymmetry and Branes in M-theory Plane-waves

We study brane embeddings in M-theory plane-waves and their supersymmetry. The relation with branes in AdS backgrounds via the Penrose limit is also explored. Longitudinal planar branes are originated from AdS branes while giant gravitons of AdS spaces become spherical branes which are realized as fuzzy spheres in the massive matrix theory.Comment: 17 pages, JHEP style, references added, typos correcte