661 research outputs found
Variable order Mittag-Leffler fractional operators on isolated time scales and application to the calculus of variations
We introduce new fractional operators of variable order on isolated time
scales with Mittag-Leffler kernels. This allows a general formulation of a
class of fractional variational problems involving variable-order difference
operators. Main results give fractional integration by parts formulas and
necessary optimality conditions of Euler-Lagrange type.Comment: This is a preprint of a paper whose final and definite form is with
Springe
The SKA and "High-Resolution" Science
"High-resolution", or "long-baseline", science with the SKA and its
precursors covers a broad range of topics in astrophysics. In several research
areas, the coupling between improved brightness sensitivity of the SKA and a
sub-arcsecond resolution would uncover truly unique avenues and opportunities
for studying extreme states of matter, vicinity of compact relativistic
objects, and complex processes in astrophysical plasmas. At the same time, long
baselines would secure excellent positional and astrometric measurements with
the SKA and critically enhance SKA image fidelity at all scales. The latter
aspect may also have a substantial impact on the survey speed of the SKA, thus
affecting several key science projects of the instrument.Comment: JENAM-2010: Invited talk at JENAM session S7: The Square Kilometre
Array: Paving the way for the new 21st century radio astronomy paradigm; 9
page
Thermoelectric and Structural Properties of Sputtered AZO Thin Films with Varying Al Doping Ratios
Nanomaterials can be game-changers in the arena of sustainable energy production because they may enable highly efficient thermoelectric energy conversion and harvesting. For this purpose, doped thin film oxides have been proven to be promising systems for achieving high thermoelectric performances. In this work, the design, realization, and experimental investigation of the thermoelectric properties exhibited by a set of five Al:ZnO thin films with thicknesses of 300 nm and Al doping levels ranging from 2 to 8 at.% are described. Using a multi-technique approach, the main structural and morphological features of the grown thin films are addressed, as well as the electrical and thermoelectrical transport properties. The results show that the samples exhibited a Seebeck coefficient absolute value in the range of 22-33 mu V/K, assuming their maximum doping level was 8 at.%, while the samples' resistivity was decreased below 2 x 10(-3) Ohm center dot cm with a doping level of 3 at.%. The findings shine light on the perspectives of the applications of the metal ZnO thin film technology for thermoelectrics
Massive Spin-2 States as the Origin of the Top Quark Forward-Backward Asymmetry
We show that the anomalously large top quark forward-backward asymmetry
observed by CDF and D\O\, can naturally be accommodated in models with
flavor-violating couplings of a new massive spin-2 state to quarks. Regardless
of its origin, the lowest-order couplings of a spin-2 boson to fermions are
analogous to the coupling of the graviton to energy/momentum, leading to strong
sensitivity of the effects associated with its virtual exchange to the energy
scales at hand. Precisely due to this fact, the observed dependence of the
asymmetry on the invariant mass fits nicely into the proposed
framework. In particular, we find a vast parameter space which can lead to the
central value for the observed forward-backward asymmetry in the high mass bin,
while being in accord with all of the existing experimental constraints.Comment: added discussion of differential observables at the LHC, matches
version accepted for publication in JHE
Deleterious phases precipitation on superduplex stainless steel UNS S32750: characterization by light optical and scanning electron microscopy
Effects of external nutrient sources and extreme weather events on the nutrient budget of a Southern European coastal lagoon
The seasonal and annual nitrogen (N), phosphorus (P), and carbon (C) budgets of the mesotidal Ria Formosa lagoon, southern Portugal, were estimated to reveal the main inputs and outputs, the seasonal patterns, and how they may influence the ecological functioning of the system. The effects of extreme weather events such as long-lasting strong winds causing upwelling and strong rainfall were assessed. External nutrient inputs were quantified; ocean exchange was assessed in 24-h sampling campaigns, and final calculations were made using a hydrodynamic model of the lagoon. Rain and stream inputs were the main freshwater sources to the lagoon. However, wastewater treatment plant and groundwater discharges dominated nutrient input, together accounting for 98, 96, and 88 % of total C, N, and P input, respectively. Organic matter and nutrients were continuously exported to the ocean. This pattern was reversed following extreme events, such as strong winds in early summer that caused upwelling and after a period of heavy rainfall in late autumn. A principal component analysis (PCA) revealed that ammonium and organic N and C exchange were positively associated with temperature as opposed to pH and nitrate. These variables reflected mostly the benthic lagoon metabolism, whereas particulate P exchange was correlated to Chl a, indicating that this was more related to phytoplankton dynamics. The increase of stochastic events, as expected in climate change scenarios, may have strong effects on the ecological functioning of coastal lagoons, altering the C and nutrient budgets.Portuguese Science and Technology Foundation (FCT) [POCI/MAR/58427/2004, PPCDT/MAR/58427/2004]; Portuguese Science and Technology Foundation (FCT
Clinical and genetic characterization of leukoencephalopathies in adults
Leukodystrophies and genetic leukoencephalopathies are a rare group of disorders leading to progressive degeneration of cerebral white matter. They are associated with a spectrum of clinical phenotypes dominated by dementia, psychiatric changes, movement disorders and upper motor neuron signs. Mutations in at least 60 genes can lead to leukoencephalopathy with often overlapping clinical and radiological presentations. For these reasons, patients with genetic leukoencephalopathies often endure a long diagnostic odyssey before receiving a definitive diagnosis or may receive no diagnosis at all. In this study, we used focused and whole exome sequencing to evaluate a cohort of undiagnosed adult patients referred to a specialist leukoencephalopathy service. In total, 100 patients were evaluated using focused exome sequencing of 6100 genes. We detected pathogenic or likely pathogenic variants in 26 cases. The most frequently mutated genes were NOTCH3, EIF2B5, AARS2 and CSF1R. We then carried out whole exome sequencing on the remaining negative cases including four family trios, but could not identify any further potentially disease-causing mutations, confirming the equivalence of focused and whole exome sequencing in the diagnosis of genetic leukoencephalopathies. Here we provide an overview of the clinical and genetic features of these disorders in adults
Behavioral and Autonomic Responses to Acute Restraint Stress Are Segregated within the Lateral Septal Area of Rats
Background: The Lateral Septal Area (LSA) is involved with autonomic and behavior responses associated to stress. In rats, acute restraint (RS) is an unavoidable stress situation that causes autonomic (body temperature, mean arterial pressure (MAP) and heart rate (HR) increases) and behavioral (increased anxiety-like behavior) changes in rats. The LSA is one of several brain regions that have been involved in stress responses. The aim of the present study was to investigate if the neurotransmission blockade in the LSA would interfere in the autonomic and behavioral changes induced by RS. Methodology/Principal Findings: Male Wistar rats with bilateral cannulae aimed at the LSA, an intra-abdominal datalogger (for recording internal body temperature), and an implanted catheter into the femoral artery (for recording and cardiovascular parameters) were used. They received bilateral microinjections of the non-selective synapse blocker cobalt chloride (CoCl2, 1 mM / 100 nL) or vehicle 10 min before RS session. The tail temperature was measured by an infrared thermal imager during the session. Twenty-four h after the RS session the rats were tested in the elevated plus maze (EPM). Conclusions/Significance: Inhibition of LSA neurotransmission reduced the MAP and HR increases observed during RS. However, no changes were observed in the decrease in skin temperature and increase in internal body temperature observed during this period. Also, LSA inhibition did not change the anxiogenic effect induced by RS observed 24 h later in the EPM. The present results suggest that LSA neurotransmission is involved in the cardiovascular but not the temperatur
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