Evaluación de la dinámica temporal de la materia orgánica en la cuenca de klyazma utilizando monitoreo remoto y qgis trends.earth

El artículo está dedicado al estudio de la dinámica de los procesos biológicos en los paisajes en los limites de la zona de captación. Se eligió como zona modelo la cuenca del río Klyazma (que esta entrando con un afluente de cuarto orden a la cuenca del Volga), que es una combinación bastante compleja de diferentes paisajes. El estudio se basó en datos de teledetección. Se eligieron como parámetros los indicadores de fito-productividad y de carbono del suelo. Se estableció que en los distintos paisajes los procesos biológicos difieren tanto en velocidad como en intensidad y responden de forma ambigua a los cambios en los parámetros climáticos y al cambio en el uso del suelo. Sin embargo, en general, la cuenca hidrográfica, como ecosistema único, mostró suficiente estabilidad en los procesos dinámicos. Esto indica que los ecosistemas naturales holísticos tienen internas propiedades compensatoria

NATURAL-FOCAL DISEASES IN THE VLADIMIR REGION (RUSSIA)

The paper describes a study that monitored the epidemiological situation of a complex of natural-focal diseases in the Vladimir region (Russia), from 1958 to 2012. The morbidity rates of these natural-focal diseases have been differentiated by territory using ArcView 3.1 (GIS software). The activity of natural foci for each zooanthroponosis varied between administrative districts in the region. A schematic map has been compiled; the map reflectsthe danger of infection caused by natural-focal diseases in the Vladimir region. The paperdiscusses the role of the anthropogenic factor in natural-ecosystem development: it likelypromotes the transit and localization rates of carriers. Correlation and regression analysis ofthe data showed that climatic factors such as the average temperatures in July and September in the preceding year influence Lyme disease (Lyme borreliosis) patterns. This is likely related to particular stages in the life cycle of Ixodidae ticks. Using multiple linear regression analysis, a mathematical model for the prediction of Lyme borreliosis patterns has been created

Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re₆Q₈}(CN)₆]^4– (Q = S, Se, Te)

Octahedral rhenium cluster complexes have recently emerged as relevant building blocks for the design of singlet oxygen photosensitizing materials toward biological applications such as blue-light photodynamic therapy. However, their singlet oxygen generation ability as well as biological properties have been studied only superficially. Herein we investigate in detail the singlet oxygen photogeneration, dark and photoinduced cytotoxicity, cellular uptake kinetics, cellular localization and in vitro photoinduced oxidative stress, and photodynamic cytotoxicity of the series of octahedral rhenium cluster complexes [{Re₆Q₈}­(CN)₆]^4–, where Q = S, Se, Te. Our results demonstrate that the selenium-containing complex possesses optimal properties in terms of absorption and singlet oxygen productivity. These features coupled with the cellular internalization and low dark toxicity lead to the first photoinduced cytotoxic effect observed for a molecular [{M₆Q₈}­L₆] complex, making it a promising object for further study in terms of blue-light PDT

Health-status outcomes with invasive or conservative care in coronary disease

BACKGROUND In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or severe ischemia. A secondary objective of the trial was to assess angina-related health status among these patients. METHODS We assessed angina-related symptoms, function, and quality of life with the Seattle Angina Questionnaire (SAQ) at randomization, at months 1.5, 3, and 6, and every 6 months thereafter in participants who had been randomly assigned to an invasive treatment strategy (2295 participants) or a conservative strategy (2322). Mixed-effects cumulative probability models within a Bayesian framework were used to estimate differences between the treatment groups. The primary outcome of this health-status analysis was the SAQ summary score (scores range from 0 to 100, with higher scores indicating better health status). All analyses were performed in the overall population and according to baseline angina frequency. RESULTS At baseline, 35% of patients reported having no angina in the previous month. SAQ summary scores increased in both treatment groups, with increases at 3, 12, and 36 months that were 4.1 points (95% credible interval, 3.2 to 5.0), 4.2 points (95% credible interval, 3.3 to 5.1), and 2.9 points (95% credible interval, 2.2 to 3.7) higher with the invasive strategy than with the conservative strategy. Differences were larger among participants who had more frequent angina at baseline (8.5 vs. 0.1 points at 3 months and 5.3 vs. 1.2 points at 36 months among participants with daily or weekly angina as compared with no angina). CONCLUSIONS In the overall trial population with moderate or severe ischemia, which included 35% of participants without angina at baseline, patients randomly assigned to the invasive strategy had greater improvement in angina-related health status than those assigned to the conservative strategy. The modest mean differences favoring the invasive strategy in the overall group reflected minimal differences among asymptomatic patients and larger differences among patients who had had angina at baseline

Initial invasive or conservative strategy for stable coronary disease

BACKGROUND Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, 121.8 percentage points; 95% CI, 124.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used

Spectroscopy in beauty decays at the LHCb experiment

The beauty hadron decays is unique laboratory to study charmonium and charmonium-like states, such as the $\chi_{c1}(3872)$ meson, other exotic states and the tensor $D$-wave $\Psi_2(3823)$ states. However the nature of many exotic charmonium-like candidates are still unknown. The most recent LHCb results related to b-hadron decays to charmonium states and obtained using large data samples collected during the Run 1 and Run 2 periods are presented. This includes the most precise determination of the mass and width of the $\chi_{c1}(3872)$ state using the $B^{+} \to J/\psi\pi^{+}\pi^{-}K^{+}$ decays, observation of a resonant structure denoted as X(4740) in the $J\psi \phi$ mass spectrum from $B^{0}_{s} \to J/\psi\pi^{+}\pi^{-}K^{+}K^{-}$ decays and the precise measurement of the $B^{0}_{s}$~meson mass.The beauty hadron decays is unique laboratory to study charmonium and charmonium-like states, such as the $\chi_{c1}(3872)$ meson, other exotic states and the tensor D-wave $\psi_2(3823$) states. However the nature of many exotic charmonium-like candidates are still unknown. The most recent LHCb results related to b-hadron decays to charmonium states and obtained using large data samples collected during the Run 1 and Run 2 periods are presented. This includes the most precise determination of the mass and width of the $\chi_{c1}(3872)$ state using the $B^{+} \to J/\psi\pi^{+}\pi^{-}K^{+}$ decays, observation of a resonant structure denoted as X(4740) in the $J/\psi \phi$ mass spectrum from $B^{0}_{s} \to J/\psi\pi^{+}\pi^{-}K^{+}K^{-}$ decays and the precise measurement of the $B^{0}_{s}$ meson mass

Measurement of the Λb0→J/ψΛ\Lambda^0_b\rightarrow J/\psi\Lambda angular distribution and the Λb0\Lambda^0_b polarisation in pppp collisions

International audienceThis paper presents an analysis of the ${\Lambda}_b^0$→ J/ψΛ angular distribution and the transverse production polarisation of ${\Lambda}_b^0$ baryons in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV. The measurements are performed using data corresponding to an integrated luminosity of 4.9 fb$^{−1}$, collected with the LHCb experiment. The polarisation is determined in a fiducial region of ${\Lambda}_b^0$ transverse momentum and pseudorapidity of 1 < p$_{T}$< 20 GeV/c and 2 < η < 5, respectively. The data are consistent with ${\Lambda}_b^0$ baryons being produced unpolarised in this region. The parity-violating asymmetry parameter of the Λ → pπ$^{−}$ decay is also determined from the data and its value is found to be consistent with a recent measurement by the BES III collaboration.[graphic not available: see fulltext