Shock interactions, turbulence, and the origin of the stellar mass spectrum

Supersonic turbulence is an essential element in understanding how structure within interstellar gas is created and shaped. In the context of star formation, many computational studies show that the mass spectrum of density and velocity fluctuations within dense clouds, as well as the distribution of their angular momenta, trace their origin to the statistical and physical properties of gas that is lashed with shock waves. In this article, we review the observations, simulations, and theories of how turbulent-like processes can account for structures we see in molecular clouds. We then compare traditional ideas of supersonic turbulence with a simpler physical model involving the effects of multiple shock waves and their interaction in the interstellar medium. Planar intersecting shock waves produce dense filaments, and generate vortex sheets that are essential to create the broad range of density and velocity structure in clouds. As an example, the lower mass behaviour of the stellar initial mass function can be traced to the tendency of a collection of shock waves to build-up a log-normal density distribution (or column density). Vorticity - which is essential to produce velocity structure over a very broad range of length scales in shocked clouds - can also be generated by the passage of curved shocks or intersecting planar shocks through such media. Two major additional physical forces affect the structure of star forming gas - gravity and feedback processes from young stars. Both of these can produce power-law tails at the high mass end of the IMF.Comment: 20 pages, 5 figures, to appear in theme issue "Turbulent Mixing" of the Philosophical Transactions of the Royal Society A, Snezhana I. Abarzhi, Serge Gauthier, and Katepalli R. Sreenivasan (Guest Editors), accepted for publicatio

The changing GMC population in galaxy interactions

This is the final version. Available from OUP via the DOI in this recordWith the advent of modern observational efforts providing extensive giant molecular cloud catalogues, understanding the evolution of such clouds in a galactic context is of prime importance. While numerous previous numerical and theoretical works have focused on the cloud properties in isolated discs, few have looked into the cloud population in an interacting disc system. We present results of the first study investigating the evolution of the cloud population in galaxy experiencing an M51-like tidal fly-by using numerical simulations including star formation, interstellar medium cooling, and stellar feedback. We see the cloud population shift to large unbound clouds in the wake of the companion passage, with the largest clouds appearing as fleeting short-lived agglomerations of smaller clouds within the tidal spiral arms, brought together by large-scale streaming motions. These are then sheared apart as they leave the protection of the spiral arms. Clouds appear to lead diverse lives, even within similar environments, with some being born from gas shocked by filaments streaming into the spiral arms, and others from effectively isolated smaller colliding pairs. Overall, this cloud population produces a shallower mass function than the disc in isolation, especially in the arms compared to the inter-arm regions. Direct comparisons to M51 observations show similarities between cloud populations, though models tailored to the mass and orbital models of M51 appear necessary to precisely reproduce the cloud population

Conversion of Amides into Esters by the Nickel-Catalyzed Activation of Amide C-N Bonds

The amide function is ubiquitous in natural compounds as well as in man-made molecules and materials. It is generally very stable and poorly reactive owing to its resonance-stabilized C–N group that imparts a planar geometry to amides. In contrast, carboxylic esters are generally reactive under a variety of mild conditions; therefore, it is not surprising that a number of direct methods are available to the chemist for converting esters into amides (amino-de-alkoxylation reaction) but very few for achieving the opposite transformation. Recently, Professors Neil Garg and Ken Houk from the University of California, Los Angeles (UCLA, USA) reported in Nature a groundbreaking method for converting amides into esters with a high degree of efficiency

Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins

Delivery is a stressful and risky event menacing the newborn. The mother-dependent respiration has to be replaced by autonomous pulmonary breathing immediately after delivery. If delayed, it may lead to deficient oxygen supply compromising survival and development of the central nervous system. Lack of oxygen availability gives rise to depletion of NAD+ tissue stores, decrease of ATP formation, weakening of the electron transport pump and anaerobic metabolism and acidosis, leading necessarily to death if oxygenation is not promptly re-established. Re-oxygenation triggers a cascade of compensatory biochemical events to restore function, which may be accompanied by improper homeostasis and oxidative stress. Consequences may be incomplete recovery, or excess reactions that worsen the biological outcome by disturbed metabolism and/or imbalance produced by over-expression of alternative metabolic pathways. Perinatal asphyxia has been associated with severe neurological and psychiatric sequelae with delayed clinical onset. No specific treatments have yet been established. In the clinical setting, after resuscitation of an infant with birth asphyxia, the emphasis is on supportive therapy. Several interventions have been proposed to attenuate secondary neuronal injuries elicited by asphyxia, including hypothermia. Although promising, the clinical efficacy of hypothermia has not been fully demonstrated. It is evident that new approaches are warranted. The purpose of this review is to discuss the concept of sentinel proteins as targets for neuroprotection. Several sentinel proteins have been described to protect the integrity of the genome (e.g. PARP-1; XRCC1; DNA ligase IIIα; DNA polymerase β, ERCC2, DNA-dependent protein kinases). They act by eliciting metabolic cascades leading to (i) activation of cell survival and neurotrophic pathways; (ii) early and delayed programmed cell death, and (iii) promotion of cell proliferation, differentiation, neuritogenesis and synaptogenesis. It is proposed that sentinel proteins can be used as markers for characterising long-term effects of perinatal asphyxia, and as targets for novel therapeutic development and innovative strategies for neonatal care

AusTraits, a curated plant trait database for the Australian flora

We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge

Butyrylcholinesterase K variant associated with higher enzyme activity in the temporal cortex of elderly patients.

There is evidence to suggest an involvement of the K variant of the butyrylcholinesterase gene (BCHE) in dementia. We have examined the relationship between BCHE genotype and butyrylcholinesterase (BuChE) activity in autopsy brain tissue. We studied 164 autopsy cases, 144 with dementia and 20 controls, including 13 K homozygotes and 48 K heterozygotes, from three centres: Newcastle, Oxford and London. Mean BuChE activity in temporal cortex was 37% higher in K homozygotes than in wild-type homozygotes. Linear regression analysis, controlling for gender, diagnosis, age at death and study centre, showed that the number of BCHE-K alleles was associated with increasing BuChE activity (p=0.009)