Innovaatiotalouden moderni/koloniaalisuus : The modern/coloniality of innovation economy

Innovaatiotaloudella ja kolonialismilla vaikuttaisi ensisilmäyksellä olevan hyvin vä-hän tekemistä keskenään. Innovaatiot assosioituvat Schumpeteriin, Piilaaksoon ja digitaalisiin teknologioihin – kolonialismi purjeveneisiin ja Kolumbukseen. Esitän tässä kirjoituksessa, että kolonialismintutkimus tarjoaa hedelmällisiä lähtökohtia innovaatiotalouden ymmärtämiseen. Anibal Quijanon käsite moderni/koloniaali-suus on yksi toimiva tapa jäsentää innovaatiotalouden ja kolonialismin suhdettaNon peer reviewe

“I, Post-Palestinian Entrepreneur” : Transformations of subalternity in the “start-up nation” of Israel

This is an explorative case study on the transformations of the hegemonic self and the subaltern other in the spaces of Israel’s globalising economy. Inspired by the works of Saskia Sassen, the thesis is based on a premise that the modern binary categories of difference may transform in the spaces of global, destabilising the hegemonic state. To study this possibility, thesis collects individual imaginaries of difference from Israel where the state has started to integrate the Palestinians of Israel into the centre of Israel’s start-up economy and the key operations of global capital. The thesis deploys an innovative research design that approaches difference as imaginary, made in the living interaction of materialities, myths and creative sense-making. The data of the study consists of individual narrations of difference, collected from Israeli-Palestinian entrepreneurs and Jewish public officials who work together at the entrepreneurial spaces in Israel. The findings of the thesis demonstrate that the Palestinians of Israel who are included into the entrepreneurial space, seek to reject their Palestinian identity and past in order to escape from the national hegemonic conditions. Through analysing the sense-making of Israeli Palestinians, the thesis demonstrates that the entrepreneurial space systematically expels knowledges of otherness that do not fit into the binary logic of modernity. The thesis concludes that in essence, the entrepreneurial intervention is a tool for reproducing the modern emancipatory image of self through the inclusion of the other. At the entrepreneurial site, it is not fear but the hope of emancipation that motivates Palestinians of Israel to detach from Palestinian narratives and spaces. Zionism, it seems, is able to re-institute its binary categories of difference from within the hope that the global brings. The results of the thesis help to understand the hegemonic dynamics through which Zionism and global capital expand together into subaltern consciousness and spaces of political As imaginaries of entrepreneurial knowledge economy are expanding not just in Israel but throughout the globe, the findings of the thesis may open up analytical possibilities also elsewhere

Altered expiratory flow dynamics at peak exercise in adult men with well-controlled type 1 diabetes.

Peer reviewe

Cowpox with Severe Generalized Eruption, Finland

Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies. The hemagglutinin gene of the isolate clustered with a Russian cowpox virus strain, and more distantly, with other cowpox and vaccinia virus strains. The patient’s dog had orthopoxvirus-specific antibodies, indicating a possible transmission route

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C

Protein kinase C (PKC) isoforms play a pivotal role in the regulation of numerous cellular functions, making them extensively studied and highly attractive drug targets. Utilizing the crystal structure of the PKC delta C1B domain, we have developed hydrophobic isophthalic acid derivatives that modify PKC functions by binding to the C1 domain of the enzyme. In the present study, we aimed to improve the drug-like properties of the isophthalic acid derivatives by increasing their solubility and enhancing the binding affinity. Here we describe the design and synthesis of a series of multisubstituted pyrimidines as analogs of C1 domain - targeted isophthalates and characterize their binding affinities to the PKC alpha isoform. In contrast to our computational predictions, the scaffold hopping from phenyl to pyrimidine core diminished the binding affinity. Although the novel pyrimidines did not establish improved binding affinity for PKC alpha compared to our previous isophthalic acid derivatives, the present results provide useful structure-activity relationship data for further development of ligands targeted to the C1 domain of PKC.Peer reviewe

Quantification and valuation of ecosystem services to optimize sustainable re-use for low-productive drained peatlands

LIFEPeatLandUse (LIFE12 ENV/FI/000150) 2013 – 2018, LAYMAN’S REPORT201

Palestine +100: Stories from a century after the Nakba Edited by Basma Ghalayini. (review-essay, Antti Tarvainen) : Stories from a century after the Nakba

Political theory has been historically rich with commentaries taking the form of utopias. The collection reviewed here revisits this genre through short stories using sci-fi projects as entry points. Written by 12 Palestinian writers, Palestine +100 poses the question of what utopia means for the colonized. The book offers crucial insights into how utopia, as a mode of political theorizing, could leave behind its Eurocentric parochialism and construct alternatives to it.Peer reviewe