47 research outputs found
The vulnerability of public spaces: challenges for UK hospitals under the 'new' terrorist threat
This article considers the challenges for hospitals in the United Kingdom that arise from the threats of mass-casualty terrorism. Whilst much has been written about the role of health care as a rescuer in terrorist attacks and other mass-casualty crises, little has been written about health care as a victim within a mass-emergency setting. Yet, health care is a key component of any nation's contingency planning and an erosion of its capabilities would have a significant impact on the generation of a wider crisis following a mass-casualty event. This article seeks to highlight the nature of the challenges facing elements of UK health care, with a focus on hospitals both as essential contingency responders under the United Kingdom's civil contingencies legislation and as potential victims of terrorism. It seeks to explore the potential gaps that exist between the task demands facing hospitals and the vulnerabilities that exist within them
Randomized controlled trial of the effects of aerobic exercise on physical functioning and quality of life in lymphoma patients
Purpose
Lymphoma patients commonly experience declines in physical functioning and quality of life (QoL)
that may be reversed with exercise training.
Patients and Methods
We conducted a randomized controlled trial in Edmonton, Alberta, Canada, between 2005 and
2008 that stratified 122 lymphoma patients by major disease type and current treatment status
and randomly assigned them to usual care (UC; n 62) or 12 weeks of supervised aerobic
exercise training (AET; n 60). Our primary end point was patient-rated physical functioning
assessed by the Trial Outcome Index-Anemia. Secondary end points were overall QoL, psychosocial
functioning, cardiovascular fitness, and body composition.
Results
Follow-up assessment for our primary end point was 96% (117 of 122) at postintervention and
90% (110 of 122) at 6-month follow-up. Median adherence to the supervised exercise program
was 92%. At postintervention, AET was superior to UC for patient-rated physical functioning
(mean group difference, 9.0; 95% CI, 2.0 to 16.0; P .012), overall QoL (P .021), fatigue
(P .013), happiness (P .004), depression (P .005), general health (P .001), cardiovascular
fitness (P .001), and lean body mass (P .008). Change in peak cardiovascular fitness mediated
the change in patient-rated physical functioning. AET did not interfere with chemotherapy
completion rate or treatment response. At 6-month follow-up, AET was still borderline or
significantly superior to UC for overall QoL (P .054), happiness (P .034), and depression
(P .009) without an increased risk of disease recurrence/progression.
Conclusion
AET significantly improved important patient-rated outcomes and objective physical functioning in
lymphoma patients without interfering with medical treatments or response. Exercise training to
improve cardiovascular fitness should be considered in the management of lymphoma patients
Fantastically reasonable: ambivalence in the representation of science and technology in super-hero comics
A long-standing contrast in academic discussions of science concerns its perceived disenchanting or enchanting public impact. In one image, science displaces magical belief in unknowable entities with belief in knowable forces and processes and reduces all things to a single technical measure. In the other, science is itself magically transcendent, expressed in technological adulation and an image of scientists as wizards or priests. This paper shows that these contrasting images are also found in representations of science in super-hero comics, which, given their lowly status in Anglo-American culture, would seem an unlikely place to find such commonality with academic discourse. It is argued that this is evidence that the contrast constitutes an ambivalence arising from the dilemmas that science poses; they are shared rhetorics arising from and reflexively feeding a set of broad cultural concerns. This is explored through consideration of representations of science at a number of levels in the comics, with particular focus on the science-magic constellation, and enchanted and disenchanted imagery in representations of technology and scientists. It is concluded that super-hero comics are one cultural arena where the public meaning of science is actively worked out, an activity that unites “expert” and “non-expert” alike
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
Increasing impact of mental health presentations on New South Wales public hospital emergency departments 1999-2006
Objective: The percentage of mental health (MH) presentations to New South Wales (NSW) EDs in recent years has not been described at the statewide level. Evidence from other states suggests this burden might be increasing. The present study aims to evaluate recent trends in MH presentations to NSW EDs, including geographic variations and the spectrum of MH disorders encountered.
Methods: Data were sourced from the NSW Emergency Department Data Collection, which collates information from routine reporting undertaken in all NSW EDs. The database employs ICD-9 diagnostic descriptors. The present study retrospectively analyses presentations from 1999 to 2006 for patients who received an MH primary discharge diagnosis, as defined by ICD-9. In addition, rates of presentation for poisoning are considered. The percentage of MH presentations to the three largest hospital categories - principal referral, major metropolitan and rural base (i.e. major non-metropolitan) - is examined.
Results: During 1999 and 2006, there were 9 013 357 ED presentations at the study sites. Of these, 3.22% received an MH primary discharge diagnosis. An additional 0.93% received a diagnosis of poisoning. In 2006, there were 15 262 more MH presentations than in 1999, a 49.78% increase. Over this period, total annual ED presentations increased by 201 763 (19.30%). General population growth was 6.31%. Across the state, 32.0% of MH presentations were for psychotic conditions and 68.0% for neurotic illnesses.
Conclusion: Mental health presentations to NSW EDs are increasing. There is a need to review emergency services to accommodate these changes. The reasons for this growth remain unclear and require formal prospective evaluation
Mediastinitis in the intensive care unit patient: a narrative review
International audienc