308 research outputs found
Effect of Cu impurities on wet etching of Si(110): formation of trapezoidal hillocks
We simulate the formation of experimentally observed trapezoidal hillocks on etched Si(110) surfaces, describing their generic geometrical shape and analyzing the relative stability and/or reactivity of the key surface sites. In our model, the hillocks are stabilized by Cu impurities in the etchant adsorbing on the surface and acting as pinning agents. A model of random adsorptions will not result in hillock formation since a single impurity is easily removed from the surface. Instead a whole cluster of Cu atoms is needed as a mask to stabilize a hillock. Therefore we propose and analyze mechanisms that drive correlated adsorptions and lead to stable Cu clusters.Peer reviewe
Mechanisms of temporomandibular joint-osteoarthrosis (TMJ-OA) : Biomechanical, histological and biochemical evidences
Condylar resorption in the TMJ or TMJ-OA has been experienced occasionally in daily orthodontic practice and recognized to induce substantial influences on craniofacial morphology and the treatment outcomes. This study was designed to investigate the mechanisms of TMJ-OA by means of biomechanical, histological and biochemical approaches. Biomechanical study with finite element stress analysis revealed an existence of large compressive stresses in the anterior, middle and lateral areas on the condyle and prominent increases in the compressive stresses in association with vertical discrepancy of the craniofacial skeleton. Such skeletal discrepancy, simulated in growing rats by placing a metal plate on the upper molars, produced a decrease in the thickness of cartilage layers and an increase in the number of TRAP-positive cells, both of which lead to degenerative changes in the articular cartilage of the mandibular condyle. Furthermore, excessive tensile stresses, applied to articular chondrocytes with use of the Flexercell Strain Unit, induced an imbalance between matrix metalloproteinases(MMPs) and tissue inhibitors of matrix metalloproteinases(TIMPs), which is assumed to induce lower resistance to external stimuli and degenerative changes leading to the resorption of bone and cartilage. It is thus shown that excessive or imbalanced mechanical loading on the TMJ components from occlusal and skeletal discrepancies induce various degenerative responses of cartilaginous tissues and articular chondrocytes, leading to the destruction of bone or cartilage in TMJ-OA
Identification of 45 New Neutron-Rich Isotopes Produced by In-Flight Fission of a 238U Beam at 345 MeV/nucleon
A search for new isotopes using in-flight fission of a 345 MeV/nucleon 238U
beam has been carried out at the RI Beam Factory at the RIKEN Nishina Center.
Fission fragments were analyzed and identified by using the superconducting
in-flight separator BigRIPS. We observed 45 new neutron-rich isotopes: 71Mn,
73,74Fe, 76Co, 79Ni, 81,82Cu, 84,85Zn, 87Ga, 90Ge, 95Se, 98Br, 101Kr, 103Rb,
106,107Sr, 108,109Y, 111,112Zr, 114,115Nb, 115,116,117Mo, 119,120Tc,
121,122,123,124Ru, 123,124,125,126Rh, 127,128Pd, 133Cd, 138Sn, 140Sb, 143Te,
145I, 148Xe, and 152Ba
The Erotic and the Vulgar: Visual Culture and Organized Labor's Critique of U.S. Hegemony in Occupied Japan
This essay engages the colonial legacy of postwar Japan by arguing that the political cartoons produced as part of the postwar Japanese labor movement’s critique of U.S. cultural hegemony illustrate how gendered discourses underpinned,
and sometimes undermined, the ideologies formally represented by visual artists and the organizations that funded them. A significant component of organized
labor’s propaganda rested on a corpus of visual media that depicted women as icons of Japanese national culture. Japan’s most militant labor unions were propagating anti-imperialist discourses that invoked an engendered/endangered nation that accentuated the importance of union roles for men by subordinating, then eliminating, union roles for women
The Nature of Ultra-Luminous Compact X-Ray Sources in Nearby Spiral Galaxies
Studies were made of ASCA spectra of seven ultra-luminous compact X-ray
sources (ULXs) in nearby spiral galaxies; M33 X-8 (Takano et al. 1994), M81 X-6
(Fabbiano 1988b; Kohmura et al. 1994; Uno 1997), IC 342 Source 1 (Okada et al.
1998), Dwingeloo 1 X-1 (Reynolds et al. 1997), NGC 1313 Source B (Fabbiano &
Trinchieri 1987; Petre et al. 1994), and two sources in NGC 4565 (Mizuno et al.
1999). With the 0.5--10 keV luminosities in the range 10^{39-40} ergs/s, they
are thought to represent a class of enigmatic X-ray sources often found in
spiral galaxies. For some of them, the ASCA data are newly processed, or the
published spectra are reanalyzed. For others, the published results are quoted.
The ASCA spectra of all these seven sources have been described successfully
with so called multi-color disk blackbody (MCD) emission arising from
optically-thick standard accretion disks around black holes. Except the case of
M33 X-8, the spectra do not exhibit hard tails. For the source luminosities not
to exceed the Eddington limits, the black holes are inferred to have rather
high masses, up to ~100 solar masses. However, the observed innermost disk
temperatures of these objects, Tin = 1.1--1.8 keV, are too high to be
compatible with the required high black-hole masses, as long as the standard
accretion disks around Schwarzschild black holes are assumed. Similarly high
disk temperatures are also observed from two Galactic transients with
superluminal motions, GRO 1655-40 and GRS 1915+105. The issue of unusually high
disk temperature may be explained by the black hole rotation, which makes the
disk get closer to the black hole, and hence hotter.Comment: submitted to ApJ, December 199
Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese
Nonalcoholic fatty liver disease (NAFLD) includes a broad range of liver pathologies from simple steatosis to cirrhosis and fibrosis, in which a subtype accompanying hepatocyte degeneration and fibrosis is classified as nonalcoholic steatohepatitis (NASH). NASH accounts for approximately 10-30% of NAFLD and causes a higher frequency of liver-related death, and its progression of NASH has been considered to be complex involving multiple genetic factors interacting with the environment and lifestyle.To identify genetic factors related to NAFLD in the Japanese, we performed a genome-wide association study recruiting 529 histologically diagnosed NAFLD patients and 932 population controls. A significant association was observed for a cluster of SNPs in PNPLA3 on chromosome 22q13 with the strongest p-value of 1.4 × 10(-10) (OR = 1.66, 95%CI: 1.43-1.94) for rs738409. Rs738409 also showed the strongest association (p = 3.6 × 10(-6)) with the histological classifications proposed by Matteoni and colleagues based on the degree of inflammation, ballooning degeneration, fibrosis and Mallory-Denk body. In addition, there were marked differences in rs738409 genotype distributions between type4 subgroup corresponding to NASH and the other three subgroups (p = 4.8 × 10(-6), OR = 1.96, 95%CI: 1.47-2.62). Moreover, a subgroup analysis of NAFLD patients against controls showed a significant association of rs738409 with type4 (p = 1.7 × 10(-16), OR = 2.18, 95%CI: 1.81-2.63) whereas no association was obtained for type1 to type3 (p = 0.41). Rs738409 also showed strong associations with three clinical traits related to the prognosis of NAFLD, namely, levels of hyaluronic acid (p = 4.6 × 10(-4)), HbA1c (p = 0.0011) and iron deposition in the liver (p = 5.6 × 10(-4)).With these results we clearly demonstrated that Matteoni type4 NAFLD is both a genetically and clinically different subset from the other spectrums of the disease and that the PNPLA3 gene is strongly associated with the progression of NASH in Japanese population
The Quiescent Intracluster Medium in the Core of the Perseus Cluster
Clusters of galaxies are the most massive gravitationally-bound objects in
the Universe and are still forming. They are thus important probes of
cosmological parameters and a host of astrophysical processes. Knowledge of the
dynamics of the pervasive hot gas, which dominates in mass over stars in a
cluster, is a crucial missing ingredient. It can enable new insights into
mechanical energy injection by the central supermassive black hole and the use
of hydrostatic equilibrium for the determination of cluster masses. X-rays from
the core of the Perseus cluster are emitted by the 50 million K diffuse hot
plasma filling its gravitational potential well. The Active Galactic Nucleus of
the central galaxy NGC1275 is pumping jetted energy into the surrounding
intracluster medium, creating buoyant bubbles filled with relativistic plasma.
These likely induce motions in the intracluster medium and heat the inner gas
preventing runaway radiative cooling; a process known as Active Galactic
Nucleus Feedback. Here we report on Hitomi X-ray observations of the Perseus
cluster core, which reveal a remarkably quiescent atmosphere where the gas has
a line-of-sight velocity dispersion of 164+/-10 km/s in a region 30-60 kpc from
the central nucleus. A gradient in the line-of-sight velocity of 150+/-70 km/s
is found across the 60 kpc image of the cluster core. Turbulent pressure
support in the gas is 4% or less of the thermodynamic pressure, with large
scale shear at most doubling that estimate. We infer that total cluster masses
determined from hydrostatic equilibrium in the central regions need little
correction for turbulent pressure.Comment: 31 pages, 11 Figs, published in Nature July
Neural Correlates of Face and Object Perception in an Awake Chimpanzee (Pan Troglodytes) Examined by Scalp-Surface Event-Related Potentials
BACKGROUND: The neural system of our closest living relative, the chimpanzee, is a topic of increasing research interest. However, electrophysiological examinations of neural activity during visual processing in awake chimpanzees are currently lacking. METHODOLOGY/PRINCIPAL FINDINGS: In the present report, skin-surface event-related brain potentials (ERPs) were measured while a fully awake chimpanzee observed photographs of faces and objects in two experiments. In Experiment 1, human faces and stimuli composed of scrambled face images were displayed. In Experiment 2, three types of pictures (faces, flowers, and cars) were presented. The waveforms evoked by face stimuli were distinguished from other stimulus types, as reflected by an enhanced early positivity appearing before 200 ms post stimulus, and an enhanced late negativity after 200 ms, around posterior and occipito-temporal sites. Face-sensitive activity was clearly observed in both experiments. However, in contrast to the robustly observed face-evoked N170 component in humans, we found that faces did not elicit a peak in the latency range of 150-200 ms in either experiment. CONCLUSIONS/SIGNIFICANCE: Although this pilot study examined a single subject and requires further examination, the observed scalp voltage patterns suggest that selective processing of faces in the chimpanzee brain can be detected by recording surface ERPs. In addition, this non-invasive method for examining an awake chimpanzee can be used to extend our knowledge of the characteristics of visual cognition in other primate species
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