On the development of ‘say’ evidential markers in Japanese : a unified analysis of tte, datte and ndatte construction

Other Versio

Where does pragmatic marker tte come from? On the convergence of to ihite, to ifute and tote in the diachronic development of ‘say’ constructions in Japanese

2012-2013 > Academic research: refereed > Refereed conference paperOther Versio

On the emergence of finite structures from non-finite constructions : evidence from ‘say’ constructions in Japanese

2013-2014 > Academic research: refereed > Refereed conference paperOther Versio

Medication use and the risk of motor vehicle collisions among licensed drivers: A systematic review

OBJECTIVES: Driving under the influence of prescription and over-the-counter medication is a growing public health concern. A systematic review of the literature was performed to investigate which specific medications were associated with increased risk of motor vehicle collision (MVC). METHODS: The a priori inclusion criteria were: 1) studies published from English-language sources on or after January 1, 1960, 2) licensed drivers 15 years of age and older, 3) peer-reviewed publications, master's theses, doctoral dissertations, and conference papers, 4) studies limited to randomized control trials, cohort studies, case-control studies, or case-control type studies 5) outcome measure reported for at least one specific medication, 6) outcome measure reported as the odds or risk of a motor vehicle collision. Fourteen databases were examined along with hand-searching. Independent, dual selection of studies and data abstraction was performed. RESULTS: Fifty-three medications were investigated by 27 studies included in the review. Fifteen (28.3%) were associated with an increased risk of MVC. These included Buprenorphine, Codeine, Dihydrocodeine, Methadone, Tramadol, Levocitirizine, Diazepam, Flunitrazepam, Flurazepam, Lorazepam, Temazepam, Triazolam, Carisoprodol, Zolpidem, and Zopiclone. CONCLUSIONS: Several medications were associated with an increased risk of MVC and decreased driving ability. The associations between specific medication use and the increased risk of MVC and/or affected driving ability are complex. Future research opportunities are plentiful and worthy of such investigation