Dal flâneur alla flâneuse. Evoluzione di un profilo urbano dal XIX secolo in avanti

Dal flâneur alla flâneuse. Evoluzione di un profilo urbano dal XIX secolo in avantidi Alice TagliabueRELATORI: Prof.ssa Nicoletta Vallorani: Prof. Dino GavinelliCORSO DI LAUREA: Laurea Magistrale in Lingue, Culture e Comunicazione InternazionaleISTITUZIONE ACCADEMICA: Università degli Studi di MilanoANNO ACCADEMICO: 2008/200

Različit, ali isti: uz pomoć DNA identifikacije otkrivena iznenađujuća obojenost primjeraka Sredozemnog morskog puža stražnjoškržnjaka (Mollusca: Nudibranchia)

A peculiar eolid nudibranch showing an unknown chromatic array was found in a rocky bottom of Santa Maria al Bagno, in the Salento peninsula, Ionian Sea (Central Mediterranean Sea). This specimen, initially identified as Piseinotecus sp., was observed in situ and photographed while feeding and laying eggs close to individuals belonging to the Mediterranean Piseinotecus soussi. To assess the identity of this unexpected Piseinotecus ‘white morph’, a DNA identification approach was carried out using mitochondrial cytochrome c oxidase subunit I (COI), as it is the molecular marker mostly used to distinguish nudibranchs species. The molecular analysis unambiguously identified this specimen as Piseinotecus soussi and helped to shed lights on the striking intraspecific colour variability characterizing this rare species.Neobični primjerak eolidnog morskog puža stražnjoškržnjaka s dosad nezabilježenim obojenjem pronađen je na stjenovitom dnu lokaliteta Santa Maria al Bagno na poluotoku Salentu u Jonskom moru (središnje Sredozemno more). Ovaj primjerak, prvobitno identificiran kao Piseinotecus sp., promatran je i fotografiran dok se hranio i polagao jaja u blizini jedinki koje pripadaju sredozemnoj vrsti Piseinotecus soussi. Kako bi se otkrio identitet ovog neobičnog „bijelog oblika“ Piseinotecus sp. primjerka, provedena je identifikacija DNA pomoću mitohondrijske podjedinice citokrom c oksidaze I (COI), budući da je to molekularni marker koji se uglavnom koristi za razlikovanje vrsta stražnjoškržnjaka. Molekularna analiza nedvojbeno je identificirala ovaj primjerak kao Piseinotecus soussi i pomogla da se rasvijetli upečatljiva intraspecifična varijabilnost obojenja koja karakterizira ovu rijetku vrstu

Sediment and bottom water eDNA metabarcoding to support coastal management

Ocean sprawl and climate change exacerbate coastal erosion and flooding, resulting in habitat loss and decreasing biodiversity. To counteract these threats, different coastal defence tools have been developed, with an increasing emphasis on nature-based solutions. However, tracking the impacts of these interventions on marine benthic organisms requires appropriate sampling designs and timely investigation methods due to the dynamic nature of coastal environments. Environmental DNA metabarcoding is a promising, non-invasive, and quick technique to monitor community changes. Here, environmental DNA COI-based metabarcoding data from sediment and bottom water samples were used to characterize benthic communities at three sites along the Emilia-Romagna coast differing in the topology of coastal defence actions (from no defences to groynes and low-crested barriers) and to evaluate the effectiveness of the two sampling matrices in detecting local biodiversity. The findings revealed significant differences in the structure of the benthic communities depending on site, sample type (i.e., sediment versus bottom water), and their interaction. The three sites differ in abiotic characteristic affecting the community composition. Lido di Dante and Riccione showed higher species diversity due to the new type of substrata provided by the hard defence structure, while Foce del Bevano showed the presence of species typical of low impacted areas. Bottom water, hosting more traces of pelagic and nektonic species, showed significantly different species composition compared to sediment samples, suggesting the need to consider both matrices in coastal monitoring

Investigation on the use of fused deposition modeling for the production of IR dosage forms containing Timapiprant

: The present work focused on evaluating the feasibility of fused deposition modeling (FDM) in the development of a dosage form containing Timapiprant (TMP), also known as CHF6532, which is a novel active molecule indicated in the potential treatment of eosinophilic asthma upon oral administration. The resulting product could be an alternative, with potential towards personalization, of immediate release (IR) tablets used in the clinical studies. Formulations based on different polymeric carriers were screened, leading to the identification of a polyvinyl alcohol-based one, which turned out acceptable for versatility in terms of active ingredient content, printability and dissolution performance (i.e. capability to meet the dissolution specification set, envisaging >80% of the drug dissolved within 30 min). Following an in-depth evaluation on the influence of TMP solid state and of the voids volume resulting from printing on dissolution, few prototypes with shapes especially devised for therapy customization were successfully printed and were compliant with the dissolution specification set

Challenger Society for Marine Science: Increasing opportunity through an equity, diversity, inclusivity, and accessibility working group

The Challenger Society for Marine Science (CSMS) is the learned society for marine scientists based in the United Kingdom, with a membership of over 470 people from >100 institutions, across all academic career stages. Members of the CSMS have been interested in improving the representation of a diverse range of identities in UK marine science, largely driven by their own experiences of inequity in the discipline, such as the challenges faced by women (Hendry et al., 2020). The structural exclusion of individuals by race, sex, ethnicity, social class, disability, sexuality, and the compound sum of these factors can result in a lack of diversity during recruitment and poor retention. Since 2021, CSMS has formed the first UK-wide equity, diversity, inclusion, and accessibility (EDIA) working group for marine scientists, with the aim of coordinating action to address the causes of exclusion and to improve representation across the discipline. The group of 25 volunteers meets each month to discuss a topical agenda, and the chair of the working group sits on the council of CSMS, providing EDIA input from the working group on society-wide strategic decisions

Ketogenic dietary therapies in epilepsy: recommendations of the Italian League against Epilepsy Dietary Therapy Study Group

A stepwise increase in the utilization of ketogenic dietary therapies for drug-resistant epilepsy has been observed in Italy in the last decade, although it is still considered often underused in many centers when compared to other countries. The Dietary Therapy Study Group of the Italian League against Epilepsy proposes practical recommendations to improve shared knowledge and facilitate the application of ketogenic dietary therapies, optimizing its efficacy and tolerability. The experts involved (11 child neuropsychiatrists, two adult neurologists, one psychologist, one pharmacologist, one pediatric endocrinologist, one representative of patients' associations, and three dietitians and clinical nutritionists) responded to a survey on current clinical practice issues and were asked to discuss controversial topics related to supplementation, long-term maintenance, transition, and a multidisciplinary approach to ketogenic dietary therapies. Practical indications for patient selection, diet initiation, management, side effects prevention, and follow-up are provided

Exploiting the Potential of Integrated Public Building Data: Energy Performance Assessment of the Building Stock in a Case Study in Northern Italy

Smart management of urban built environment relies on the availability of data supporting sound policy making and guiding city renovation processes toward more sustainable and performant models. Nevertheless, public managers are unlikely to have comprehensive information on the existing building stock. In addition, tools providing effective insights on potential costs and benefits of retrofit strategies at city/district scale are hardly available. This article describes how data related to existing buildings may be effectively combined together into a so-called Building Information System, and discusses the advantages and shortcomings related to this process. At the same time, the implementation on a real case study in northern Italy demonstrates how the effort due to data harmonization and integration is able to foster applications to support policy makers in the management of the built environment and in the definition of urban sustainability strategies. Building data were harmonized according to the requirements of the international open standard CityGML, therefore facilitating the exchange of building information. The whole project was carried out while considering the characteristics of data sources that are available for each public body in Italy and, as a consequence, it may be replicated to other Italian municipalities

Energy Management of the Smart City through Information Systems and Models

Advanced analysis tools to describe the reality by data collection are fundamental for the development of urban strategies for energy management and refurbishment of the built environment. The smart city concept connects the “parts” of the urban “body” to promote a complex energy balance. The definition of the balance focuses on the time schedule of consumption and production. The possibility to store into sinks and extract energy from sources in a coordinated way can effectively introduce the paradigm of a new urban organism with circular and composite interconnections. GIS environment can provide a suitable data management system on which a smart city can be developed: City Models are customizable repository of buildings information coming from different data sources whose the level of detail of the acquired data can radically differs, ranging from open statistical and standard data to detailed and executive files coming from BIM models. Buildings within the city can be described with different accuracy and accordingly the energy results (and possible strategies and associated costs) could delineate dramatically changing scenarios. The paper analyzes the levels of detail of the building models used to provide the energy assessment of a district (as a sample of a methodological approach) carried out following national standards (UNI). A steady-state performance calculation, based on the method implemented into the national regulation, provides the energy outcome. The results change due to the level of enrichment of the GIS model by data collected from different sources and urban policies could benefit from the definition of an effective strategy of organization and data collection framework to develop and adopt this key management instrument. The combination of GIS, BIM and BEM could be the evolutionary scenario pinpointed in this first stage of analysis